Design and physicochemical properties of new fluorescent ligands of protein kinase C isozymes focused on CH/π interaction

Bioorganic and Medicinal Chemistry

Volumn 16, Issue 2, 2008, Pages 650-657

  Sugimoto, Takuya ^a   Itagaki, Koji ^a   Irie, Kazuhiro ^a  

^a KYOTO UNIVERSITY   (Japan)

Author keywords

CH interaction; Fluorescent probe; Indolactam V; Protein kinase C; Pyrroloindazole ring

Indexed keywords

FLUORESCENT DYE; INDAZOLE DERIVATIVE; INDOLACTAM V; METHYL GROUP; PHOSPHATIDYLSERINE; PROTEIN KINASE C; PROTEIN KINASE C DELTA;

ARTICLE; BINDING AFFINITY; FLUORESCENCE; PHYSICAL CHEMISTRY; PROTEIN DOMAIN; STATISTICAL SIGNIFICANCE; SYNTHESIS;

BINDING SITES; FLUORESCENT DYES; ISOENZYMES; LACTAMS, MACROCYCLIC; LIGANDS; MOLECULAR STRUCTURE; PHORBOL ESTERS; PROTEIN KINASE C; STRUCTURE-ACTIVITY RELATIONSHIP;

EID: 38549107138     PISSN: 09680896     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.bmc.2007.10.045     Document Type: Article

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