Ketoconazole, an antifungal imidazole, increases the sensitivity of rainbow trout to 17α-ethynylestradiol exposure

Aquatic Toxicology

Volumn 86, Issue 2, 2008, Pages 256-264

  Hasselberg, Linda ^a   Westerberg, Susan ^a   Wassmur, Britt ^a   Celander, Malin C ^a  

^a UNIVERSITY OF GOTHENBURG   (Sweden)

Author keywords

CYP1A; CYP3A; Ethynylestradiol; Fish; Ketoconazole; Vitellogenin

Indexed keywords

11 OXOTESTOSTERONE; BENZYLOXY 4 (TRIFLUOROMETHYL)COUMARIN O DEBENZYLOXYLASE; CYTOCHROME P450 1A; CYTOCHROME P450 3A; ESTRADIOL; ESTROGEN RECEPTOR; ETHINYLESTRADIOL; ETHOXYRESORUFIN DEETHYLASE; KETOCONAZOLE; POLYCLONAL ANTIBODY; TESTOSTERONE; UNCLASSIFIED DRUG; VITELLOGENIN;

ENZYME ACTIVITY; POLLUTION EFFECT; POLLUTION EXPOSURE; SALMONID; STEROID; XENOBIOTICS;

ANIMAL EXPERIMENT; ARTICLE; CONTROLLED STUDY; ENZYME ACTIVITY; ENZYME LINKED IMMUNOSORBENT ASSAY; FEMALE; LOW DRUG DOSE; MALE; NONHUMAN; POLYMERASE CHAIN REACTION; PRIORITY JOURNAL; PROTEIN EXPRESSION; RAINBOW TROUT; SINGLE DRUG DOSE; WESTERN BLOTTING;

ANIMALS; ANTIBODIES; ANTIFUNGAL AGENTS; BLOTTING, WESTERN; CYTOCHROME P-450 CYP1A1; CYTOCHROME P-450 CYP3A; ESTROGENS; ETHINYL ESTRADIOL; FEMALE; GENE EXPRESSION REGULATION; GONADAL HORMONES; KETOCONAZOLE; MALE; MICROSOMES, LIVER; ONCORHYNCHUS MYKISS; RNA, MESSENGER; TIME FACTORS; VITELLOGENINS;

ONCORHYNCHUS MYKISS;

EID: 38549106572     PISSN: 0166445X     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.aquatox.2007.11.006     Document Type: Article

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