메뉴 건너뛰기




Volumn 88, Issue 2, 2008, Pages 196-206

A novel and simple cell-based detection system with a collagen-encapsulated B-lymphocyte cell line as a biosensor for rapid detection of pathogens and toxins

Author keywords

Bacillus cereus; Cell based sensor; Collagen entrapment; Listeria monocytogenes; Ped 2E9 cells; Rapid diagnostics

Indexed keywords

COLLAGEN; COLLAGEN TYPE 1; LISTERIOLYSIN O; TOXIN;

EID: 38549093748     PISSN: 00236837     EISSN: 15300307     Source Type: Journal    
DOI: 10.1038/labinvest.3700703     Document Type: Article
Times cited : (87)

References (58)
  • 2
    • 0034869051 scopus 로고    scopus 로고
    • Modification of the cell based assay for brevetoxins using human cardiac voltage dependent sodium channels expressed in HEK-293 cells
    • Fairey ER, Bottein Dechraoui MY, Sheets MF, et al. Modification of the cell based assay for brevetoxins using human cardiac voltage dependent sodium channels expressed in HEK-293 cells. Biosens Bioelectron 2001;16:579-586.
    • (2001) Biosens Bioelectron , vol.16 , pp. 579-586
    • Fairey, E.R.1    Bottein Dechraoui, M.Y.2    Sheets, M.F.3
  • 3
    • 33645280631 scopus 로고    scopus 로고
    • Electrochemical microbiosensors using living cells
    • Matsue T, Shiku H. Electrochemical microbiosensors using living cells. Electrochemistry 2006;74:107-113.
    • (2006) Electrochemistry , vol.74 , pp. 107-113
    • Matsue, T.1    Shiku, H.2
  • 4
    • 15944402750 scopus 로고    scopus 로고
    • A new recombinant cell-based bioluminescent assay for sensitive androgen-like compound detection
    • Michelini E, Leskinen P, Virta M, et al. A new recombinant cell-based bioluminescent assay for sensitive androgen-like compound detection. Biosens Bioelectron 2005;20:2261-2267.
    • (2005) Biosens Bioelectron , vol.20 , pp. 2261-2267
    • Michelini, E.1    Leskinen, P.2    Virta, M.3
  • 5
    • 0024334532 scopus 로고
    • Whole-cell biosensors for environmental monitoring
    • Rawson DM, Willmer AJ, Turner AP. Whole-cell biosensors for environmental monitoring. Biosensors 1989;4:299-311.
    • (1989) Biosensors , vol.4 , pp. 299-311
    • Rawson, D.M.1    Willmer, A.J.2    Turner, A.P.3
  • 6
    • 0034861854 scopus 로고    scopus 로고
    • A genetically engineered cell-based biosensor for functional classification of agents
    • Aravanis AM, DeBusschere BD, Chruscinski AJ, et al. A genetically engineered cell-based biosensor for functional classification of agents. Biosens Bioelectron 2001;16:571-577.
    • (2001) Biosens Bioelectron , vol.16 , pp. 571-577
    • Aravanis, A.M.1    DeBusschere, B.D.2    Chruscinski, A.J.3
  • 7
    • 0034861828 scopus 로고    scopus 로고
    • Design and demonstration of an automated cell-based biosensor
    • Gray SA, Kusel JK, Shaffer KM, et al. Design and demonstration of an automated cell-based biosensor. Biosens Bioelectron 2001;16:535-542.
    • (2001) Biosens Bioelectron , vol.16 , pp. 535-542
    • Gray, S.A.1    Kusel, J.K.2    Shaffer, K.M.3
  • 8
    • 0037815127 scopus 로고    scopus 로고
    • A B cell-based sensor for rapid identification of pathogens
    • Rider TH, Petrovick MS, Nargi FE, et al. A B cell-based sensor for rapid identification of pathogens. Science 2003;301:213-215.
    • (2003) Science , vol.301 , pp. 213-215
    • Rider, T.H.1    Petrovick, M.S.2    Nargi, F.E.3
  • 9
    • 0035426409 scopus 로고    scopus 로고
    • Detection of physiologically active compounds using cell-based biosensors
    • Stenger DA, Gross GW, Keefer EW, et al. Detection of physiologically active compounds using cell-based biosensors. Trends Biotechnol 2001;19:304-309.
    • (2001) Trends Biotechnol , vol.19 , pp. 304-309
    • Stenger, D.A.1    Gross, G.W.2    Keefer, E.W.3
  • 10
    • 0034157331 scopus 로고    scopus 로고
    • Cell-based biosensors
    • Ziegler C. Cell-based biosensors. Fresenius J Anal Chem 2000;366:552-559.
    • (2000) Fresenius J Anal Chem , vol.366 , pp. 552-559
    • Ziegler, C.1
  • 11
    • 0345714850 scopus 로고    scopus 로고
    • Shedding light on microbial detection
    • Relman DA. Shedding light on microbial detection. N Engl J Med 2003;349:2162-2163.
    • (2003) N Engl J Med , vol.349 , pp. 2162-2163
    • Relman, D.A.1
  • 12
    • 33746260355 scopus 로고    scopus 로고
    • Genetically engineered pfabA pfabR bacteria: An electrochemical whole cell biosensor for detection of water toxicity
    • Neufeld T, Biran D, Popovtzer R, et al. Genetically engineered pfabA pfabR bacteria: an electrochemical whole cell biosensor for detection of water toxicity. Anal Chem 2006;78:4952-4956.
    • (2006) Anal Chem , vol.78 , pp. 4952-4956
    • Neufeld, T.1    Biran, D.2    Popovtzer, R.3
  • 13
    • 33646106804 scopus 로고    scopus 로고
    • Luminescent yeast cells entrapped in hydrogels for estrogenic endocrine disrupting chemical biodetection
    • Fine T, Leskinen P, Isobe T, et al. Luminescent yeast cells entrapped in hydrogels for estrogenic endocrine disrupting chemical biodetection. Biosens Bioelectron 2006;21:2263-2269.
    • (2006) Biosens Bioelectron , vol.21 , pp. 2263-2269
    • Fine, T.1    Leskinen, P.2    Isobe, T.3
  • 14
    • 3242735677 scopus 로고    scopus 로고
    • Development of a whole-cell-based biosensor for detecting histamine as a model toxin
    • May KM, Wang Y, Bachas LG, et al. Development of a whole-cell-based biosensor for detecting histamine as a model toxin. Anal Chem 2004;76:4156-4161.
    • (2004) Anal Chem , vol.76 , pp. 4156-4161
    • May, K.M.1    Wang, Y.2    Bachas, L.G.3
  • 15
    • 27144464851 scopus 로고    scopus 로고
    • Continuous, noninvasive monitoring of local microscopic inflammation using a genetically engineered cell-based biosensor
    • Meng Y, Kasai A, Hiramatsu N, et al. Continuous, noninvasive monitoring of local microscopic inflammation using a genetically engineered cell-based biosensor. Lab Invest 2005;85:1429-1439.
    • (2005) Lab Invest , vol.85 , pp. 1429-1439
    • Meng, Y.1    Kasai, A.2    Hiramatsu, N.3
  • 16
    • 33846139684 scopus 로고    scopus 로고
    • Hybridoma Ped-2E9 cells cultured under modified conditions can sensitively detect Listeria monocytogenes and Bacillus cereus
    • Banerjee P, Morgan MT, Rickus JL, et al. Hybridoma Ped-2E9 cells cultured under modified conditions can sensitively detect Listeria monocytogenes and Bacillus cereus. Appl Microbiol Biotechnol 2007;73:1423-1434.
    • (2007) Appl Microbiol Biotechnol , vol.73 , pp. 1423-1434
    • Banerjee, P.1    Morgan, M.T.2    Rickus, J.L.3
  • 17
    • 0242300683 scopus 로고    scopus 로고
    • Non-invasive glucose monitoring by NAD(P)H autofluorescence spectroscopy in fibroblasts and adipocytes: A model for skin glucose sensing
    • Evans ND, Gnudi L, Rolinski OJ, et al. Non-invasive glucose monitoring by NAD(P)H autofluorescence spectroscopy in fibroblasts and adipocytes: a model for skin glucose sensing. Diabetes Technol Ther 2003;5:807-816.
    • (2003) Diabetes Technol Ther , vol.5 , pp. 807-816
    • Evans, N.D.1    Gnudi, L.2    Rolinski, O.J.3
  • 18
    • 22144432969 scopus 로고    scopus 로고
    • Glucose-dependent changes in NAD(P)H-related fluorescence lifetime of adipocytes and fibroblasts in vitro: Potential for non-invasive glucose sensing in diabetes mellitus
    • Evans ND, Gnudi L, Rolinski OJ, et al. Glucose-dependent changes in NAD(P)H-related fluorescence lifetime of adipocytes and fibroblasts in vitro: potential for non-invasive glucose sensing in diabetes mellitus. J Photochem Photobiol B 2005;80:122-129.
    • (2005) J Photochem Photobiol B , vol.80 , pp. 122-129
    • Evans, N.D.1    Gnudi, L.2    Rolinski, O.J.3
  • 19
    • 0042510622 scopus 로고    scopus 로고
    • Detection and classification of neurotoxins using a novel short-term plasticity quantification method
    • Gholmieh G, Courellis S, Fakheri S, et al. Detection and classification of neurotoxins using a novel short-term plasticity quantification method. Biosens Bioelectron 2003;18:1467-1478.
    • (2003) Biosens Bioelectron , vol.18 , pp. 1467-1478
    • Gholmieh, G.1    Courellis, S.2    Fakheri, S.3
  • 20
    • 21644487903 scopus 로고    scopus 로고
    • Three-dimensional culture of melanoma cells profoundly affects gene expression profile: A high density oligonucleotide array study
    • Ghosh S, Spagnoli GC, Martin I, et al. Three-dimensional culture of melanoma cells profoundly affects gene expression profile: a high density oligonucleotide array study. J Cell Physiol 2005;204:522-531.
    • (2005) J Cell Physiol , vol.204 , pp. 522-531
    • Ghosh, S.1    Spagnoli, G.C.2    Martin, I.3
  • 21
    • 0026599417 scopus 로고
    • Micropatterned substratum adhesiveness: A model for morphogenetic cues controlling cell behavior
    • Britland S, Clark P, Connolly P, et al. Micropatterned substratum adhesiveness: a model for morphogenetic cues controlling cell behavior. Exp Cell Res 1992;198:124-129.
    • (1992) Exp Cell Res , vol.198 , pp. 124-129
    • Britland, S.1    Clark, P.2    Connolly, P.3
  • 22
    • 0026833080 scopus 로고
    • Micropatterning proteins and synthetic peptides on solid supports: A novel application for microelectronics fabrication technology
    • Britland S, Perez-Arnaud E, Clark P, et al. Micropatterning proteins and synthetic peptides on solid supports: a novel application for microelectronics fabrication technology. Biotechnol Prog 1992;8:155-160.
    • (1992) Biotechnol Prog , vol.8 , pp. 155-160
    • Britland, S.1    Perez-Arnaud, E.2    Clark, P.3
  • 23
    • 0026786001 scopus 로고
    • Cell guidance by micropatterned adhesiveness in vitro
    • Clark P, Connolly P, Moores GR. Cell guidance by micropatterned adhesiveness in vitro. J Cell Sci 1992;103:287-292.
    • (1992) J Cell Sci , vol.103 , pp. 287-292
    • Clark, P.1    Connolly, P.2    Moores, G.R.3
  • 24
    • 0030898088 scopus 로고    scopus 로고
    • A cell-based immunobiosensor with engineered molecular recognition - Part I: Design feasibility
    • Pizziconi VB, Page DL. A cell-based immunobiosensor with engineered molecular recognition - Part I: design feasibility. Biosens Bioelectron 1997;12:287-299.
    • (1997) Biosens Bioelectron , vol.12 , pp. 287-299
    • Pizziconi, V.B.1    Page, D.L.2
  • 27
    • 0031429763 scopus 로고    scopus 로고
    • Biocompatible, glucose-permeable hydrogel for in situ coating of implantable biosensors
    • Quinn CA, Connor RE, Heller A. Biocompatible, glucose-permeable hydrogel for in situ coating of implantable biosensors. Biomaterials 1997;18:1665-1670.
    • (1997) Biomaterials , vol.18 , pp. 1665-1670
    • Quinn, C.A.1    Connor, R.E.2    Heller, A.3
  • 28
    • 33745595659 scopus 로고    scopus 로고
    • Cartilage tissue engineering chondrocytes embedded in using human auricular different hydrogel materials
    • Yamaoka H, Asato H, Ogasawara T, et al. Cartilage tissue engineering chondrocytes embedded in using human auricular different hydrogel materials. J Biomed Mater Res A 2006;78A:1-11.
    • (2006) J Biomed Mater Res A , vol.78 A , pp. 1-11
    • Yamaoka, H.1    Asato, H.2    Ogasawara, T.3
  • 29
    • 0037785275 scopus 로고    scopus 로고
    • Mechanical characterization of collagen fibers and scaffolds for tissue engineering
    • Gentleman E, Lay AN, Dickerson DA, et al. Mechanical characterization of collagen fibers and scaffolds for tissue engineering. Biomaterials 2003;24:3805-3813.
    • (2003) Biomaterials , vol.24 , pp. 3805-3813
    • Gentleman, E.1    Lay, A.N.2    Dickerson, D.A.3
  • 30
    • 33645509724 scopus 로고    scopus 로고
    • Design of a novel fibronectin-mimetic peptide-amphiphile for functionalized biomaterials
    • Mardilovich A, Craig JA, McCammon MQ, et al. Design of a novel fibronectin-mimetic peptide-amphiphile for functionalized biomaterials. Langmuir 2006;22:3259-3264.
    • (2006) Langmuir , vol.22 , pp. 3259-3264
    • Mardilovich, A.1    Craig, J.A.2    McCammon, M.Q.3
  • 33
    • 0028397117 scopus 로고
    • Cell-aggregation and Neurite growth in gels of extracellular-matrix molecules
    • Krewson CE, Chung SW, Dai WG, et al. Cell-aggregation and Neurite growth in gels of extracellular-matrix molecules. Biotechnol Bioeng 1994;43:555-562.
    • (1994) Biotechnol Bioeng , vol.43 , pp. 555-562
    • Krewson, C.E.1    Chung, S.W.2    Dai, W.G.3
  • 34
    • 0033959231 scopus 로고    scopus 로고
    • Immobilization of neural cells in three-dimensional matrices for biosensor applications
    • O'Connor SM, Andreadis JD, Shaffer KM, et al. Immobilization of neural cells in three-dimensional matrices for biosensor applications. Biosens Bioelectron 2000;14:871-881.
    • (2000) Biosens Bioelectron , vol.14 , pp. 871-881
    • O'Connor, S.M.1    Andreadis, J.D.2    Shaffer, K.M.3
  • 35
    • 31044445103 scopus 로고    scopus 로고
    • Human neuroblastoma (SH-SY5Y) cell culture and differentiation in 3-D collagen hydrogels for cell-based biosensing
    • Desai A, Kisaalita WS, Keith C, et al. Human neuroblastoma (SH-SY5Y) cell culture and differentiation in 3-D collagen hydrogels for cell-based biosensing. Biosens Bioelectron 2006;21:1483-1492.
    • (2006) Biosens Bioelectron , vol.21 , pp. 1483-1492
    • Desai, A.1    Kisaalita, W.S.2    Keith, C.3
  • 36
    • 1342264259 scopus 로고    scopus 로고
    • Characterization of 3-D collagen hydrogels for functional cell-based biosensing
    • Mao C, Kisaalita WS. Characterization of 3-D collagen hydrogels for functional cell-based biosensing. Biosens Bioelectron 2004;19:1075-1088.
    • (2004) Biosens Bioelectron , vol.19 , pp. 1075-1088
    • Mao, C.1    Kisaalita, W.S.2
  • 37
    • 30744467461 scopus 로고    scopus 로고
    • Rapid Ped-2E9 cell-based cytotoxicity analysis and genotyping of Bacillus species
    • Gray KM, Banada PP, O'Neal E, et al. Rapid Ped-2E9 cell-based cytotoxicity analysis and genotyping of Bacillus species. J Clin Microbiol 2005;43:5865-5872.
    • (2005) J Clin Microbiol , vol.43 , pp. 5865-5872
    • Gray, K.M.1    Banada, P.P.2    O'Neal, E.3
  • 38
    • 10044232844 scopus 로고    scopus 로고
    • Specific detection of cytopathogenic Listeria monocytogenes using a two-step method of immunoseparation and cytotoxicity analysis
    • Gray KM, Bhunia AK. Specific detection of cytopathogenic Listeria monocytogenes using a two-step method of immunoseparation and cytotoxicity analysis. J Microbiol Methods 2005;60:259-268.
    • (2005) J Microbiol Methods , vol.60 , pp. 259-268
    • Gray, K.M.1    Bhunia, A.K.2
  • 39
    • 0028291713 scopus 로고
    • A six-hour in vitro virulence assay for Listeria monocytogenes using myeloma and hybridoma cells from murine and human sources
    • Bhunia AK, Steele PJ, Westbrook DG, et al. A six-hour in vitro virulence assay for Listeria monocytogenes using myeloma and hybridoma cells from murine and human sources. Microb Pathog 1994;16:99-110.
    • (1994) Microb Pathog , vol.16 , pp. 99-110
    • Bhunia, A.K.1    Steele, P.J.2    Westbrook, D.G.3
  • 40
    • 0031842776 scopus 로고    scopus 로고
    • Alkaline phosphatase release assay to determine cytotoxicity for Listeria species
    • Bhunia AK, Westbrook DG. Alkaline phosphatase release assay to determine cytotoxicity for Listeria species. Lett Appl Microbiol 1998;26:305-310.
    • (1998) Lett Appl Microbiol , vol.26 , pp. 305-310
    • Bhunia, A.K.1    Westbrook, D.G.2
  • 41
    • 0028804979 scopus 로고
    • Frozen stored murine hybridoma cells can be used to determine the virulence of Listeria monocytogenes
    • Bhunia AK, Westbrook DG, Story R, et al. Frozen stored murine hybridoma cells can be used to determine the virulence of Listeria monocytogenes. J Clin Microbiol 1995;33:3349-3351.
    • (1995) J Clin Microbiol , vol.33 , pp. 3349-3351
    • Bhunia, A.K.1    Westbrook, D.G.2    Story, R.3
  • 42
    • 0023261448 scopus 로고
    • Potential use of continuous cell lines to distinguish between pathogenic and nonpathogenic Listeria spp
    • Farber JM, Speirs JI. Potential use of continuous cell lines to distinguish between pathogenic and nonpathogenic Listeria spp. J Clin Microbiol 1987;25:1463-1466.
    • (1987) J Clin Microbiol , vol.25 , pp. 1463-1466
    • Farber, J.M.1    Speirs, J.I.2
  • 43
    • 0037448140 scopus 로고    scopus 로고
    • Hypovirulent Listeria monocytogenes strains are less frequently recovered than virulent strains on PALCAM and Rapid' L. mono media
    • Gracieux P, Roche SM, Pardon P, et al. Hypovirulent Listeria monocytogenes strains are less frequently recovered than virulent strains on PALCAM and Rapid' L. mono media. Int J Food Microbiol 2003;83:133-145.
    • (2003) Int J Food Microbiol , vol.83 , pp. 133-145
    • Gracieux, P.1    Roche, S.M.2    Pardon, P.3
  • 44
    • 0025752604 scopus 로고
    • Cytopathogenic effects in enterocytelike Caco-2 cells differentiate virulent from avirulent Listeria strains
    • Pine L, Kathariou S, Quinn F, et al. Cytopathogenic effects in enterocytelike Caco-2 cells differentiate virulent from avirulent Listeria strains. J Clin Microbiol 1991;29:990-996.
    • (1991) J Clin Microbiol , vol.29 , pp. 990-996
    • Pine, L.1    Kathariou, S.2    Quinn, F.3
  • 45
    • 0035882234 scopus 로고    scopus 로고
    • Assessment of the virulence of Listeria monocytogenes: Agreement between a plaque-forming assay with HT-29 cells and infection of immunocompetent mice
    • Roche SM, Velge P, Bottreau E, et al. Assessment of the virulence of Listeria monocytogenes: agreement between a plaque-forming assay with HT-29 cells and infection of immunocompetent mice. Int J Food Microbiol 2001;68:33-44.
    • (2001) Int J Food Microbiol , vol.68 , pp. 33-44
    • Roche, S.M.1    Velge, P.2    Bottreau, E.3
  • 46
    • 0142028198 scopus 로고    scopus 로고
    • Development of a rapid 1-h fluorescence-based cytotoxicity assay for Listeria species
    • Shroyer ML, Bhunia AK. Development of a rapid 1-h fluorescence-based cytotoxicity assay for Listeria species. J Microbiol Methods 2003;55:35-40.
    • (2003) J Microbiol Methods , vol.55 , pp. 35-40
    • Shroyer, M.L.1    Bhunia, A.K.2
  • 47
    • 0344172829 scopus 로고    scopus 로고
    • Examination of cytopathic effect and apoptosis in Listeria monocytogenes-infected hybridoma B-lymphocyte (Ped-2E9) line in vitro
    • Bhunia AK, Feng X. Examination of cytopathic effect and apoptosis in Listeria monocytogenes-infected hybridoma B-lymphocyte (Ped-2E9) line in vitro. J Microbiol Biotechnol 1999;9:398-403.
    • (1999) J Microbiol Biotechnol , vol.9 , pp. 398-403
    • Bhunia, A.K.1    Feng, X.2
  • 48
    • 33745958826 scopus 로고    scopus 로고
    • Hyperchromatic cytometry principles for cytomics using slide based cytometry
    • Mittag A, Lenz D, Gerstner AO, et al. Hyperchromatic cytometry principles for cytomics using slide based cytometry. Cytometry A 2006;69:691-703.
    • (2006) Cytometry A , vol.69 , pp. 691-703
    • Mittag, A.1    Lenz, D.2    Gerstner, A.O.3
  • 49
    • 33645909883 scopus 로고    scopus 로고
    • Laser scanning cytometry in human brain slices
    • Mosch B, Mittag A, Lenz D, et al. Laser scanning cytometry in human brain slices. Cytometry A 2006;69:135-138.
    • (2006) Cytometry A , vol.69 , pp. 135-138
    • Mosch, B.1    Mittag, A.2    Lenz, D.3
  • 50
    • 0031050462 scopus 로고    scopus 로고
    • Influence of non-essential amino acids on apoptotic and necrotic death of mouse hybridoma cells in batch cultures
    • Fassnacht D, Rössing S, Ghaussy N, et al. Influence of non-essential amino acids on apoptotic and necrotic death of mouse hybridoma cells in batch cultures. Biotechnol Lett 1997;19:35-38.
    • (1997) Biotechnol Lett , vol.19 , pp. 35-38
    • Fassnacht, D.1    Rössing, S.2    Ghaussy, N.3
  • 51
    • 0033587794 scopus 로고    scopus 로고
    • Bcl-2 over-expression reduces growth rate and prolongs G1 phase in continuous chemostat cultures of hybridoma cells
    • Simpson NH, Singh RP, Emery AN, et al. Bcl-2 over-expression reduces growth rate and prolongs G1 phase in continuous chemostat cultures of hybridoma cells. Biotechnol Bioeng 1999;64:174-186.
    • (1999) Biotechnol Bioeng , vol.64 , pp. 174-186
    • Simpson, N.H.1    Singh, R.P.2    Emery, A.N.3
  • 52
    • 16644396584 scopus 로고    scopus 로고
    • Comparison of a visual to a computer-assisted technique for detecting apoptosis
    • Goodyear-Bruch C, Simon K, Hall S, et al. Comparison of a visual to a computer-assisted technique for detecting apoptosis. Biol Res Nurs 2005;6:180-186.
    • (2005) Biol Res Nurs , vol.6 , pp. 180-186
    • Goodyear-Bruch, C.1    Simon, K.2    Hall, S.3
  • 53
    • 26844461472 scopus 로고    scopus 로고
    • A simple technique for quantifying apoptosis in 96-well plates
    • Ribble D, Goldstein NB, Norris DA, et al. A simple technique for quantifying apoptosis in 96-well plates. BMC Biotechnol 2005;5:12.
    • (2005) BMC Biotechnol , vol.5 , pp. 12
    • Ribble, D.1    Goldstein, N.B.2    Norris, D.A.3
  • 54
    • 0345268648 scopus 로고    scopus 로고
    • In vitro study of Listeria monocytogenes infection to murine primary and human transformed B cells
    • Menon A, Shroyer ML, Wampler JL, et al. In vitro study of Listeria monocytogenes infection to murine primary and human transformed B cells. Comp Immunol Microbiol Infect Dis 2003;26:157-174.
    • (2003) Comp Immunol Microbiol Infect Dis , vol.26 , pp. 157-174
    • Menon, A.1    Shroyer, M.L.2    Wampler, J.L.3
  • 55
    • 0037357723 scopus 로고    scopus 로고
    • Integration of cell culture and microfabrication technology
    • Park TH, Shuler ML. Integration of cell culture and microfabrication technology. Biotechnol Prog 2003;19:243-253.
    • (2003) Biotechnol Prog , vol.19 , pp. 243-253
    • Park, T.H.1    Shuler, M.L.2
  • 56
    • 0030334665 scopus 로고    scopus 로고
    • High-density hybridoma perfusion culture. Limitation vs inhibition
    • Banik GG, Heath CA. High-density hybridoma perfusion culture. Limitation vs inhibition. Appl Biochem Biotechnol 1996;61:211-229.
    • (1996) Appl Biochem Biotechnol , vol.61 , pp. 211-229
    • Banik, G.G.1    Heath, C.A.2
  • 57
    • 17144425366 scopus 로고    scopus 로고
    • Evaluation of diffusion in gel entrapment cell culture within hollow fibers
    • Wu DQ, Zhang GL, Shen C, et al. Evaluation of diffusion in gel entrapment cell culture within hollow fibers. World J Gastroenterol 2005;11:1599-1604.
    • (2005) World J Gastroenterol , vol.11 , pp. 1599-1604
    • Wu, D.Q.1    Zhang, G.L.2    Shen, C.3
  • 58
    • 33749367964 scopus 로고    scopus 로고
    • Lymphocyte apoptosis as an immune subversion strategy of microbial pathogens
    • Carrero JA, Unanue ER. Lymphocyte apoptosis as an immune subversion strategy of microbial pathogens. Trends Immunol 2006;27:497-503.
    • (2006) Trends Immunol , vol.27 , pp. 497-503
    • Carrero, J.A.1    Unanue, E.R.2


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.