Antibacterial evaluations of thiazomycin - A potent thiazolyl peptide antibiotic from Amycolatopsis fastidiosa

Journal of Antibiotics

Volumn 60, Issue 9, 2007, Pages 565-571

  Singh, Sheo B ^a   Occi, James ^a   Jayasuriya, Hiranthi ^a   Herath, Kithsiri ^a   Motyl, Mary ^a   Dorso, Karen ^a   Gill, Charles ^a   Hickey, Emily ^a   Overbye, Karen M ^a   Barrett, John F ^a   Masurekar, Prakash ^a  

^a MERCK RESEARCH LABORATORIES   (United States)

Author keywords

Antibiotics; Natural products; Protein synthesis inhibitors; Thiazolyl peptide

Indexed keywords

AMINOSUGAR; BETA LACTAM; GENOMIC DNA; OXAZOLIDINONE DERIVATIVE; POLYPEPTIDE ANTIBIOTIC AGENT; QUINOLONE DERIVATIVE; RNA 23S; THIAZOMYCIN; UNCLASSIFIED DRUG; VANCOMYCIN; ANTIINFECTIVE AGENT; CYCLOPEPTIDE; PEPTIDE; PROTEIN SYNTHESIS INHIBITOR; RIBOSOME RNA; THIAZOLE DERIVATIVE;

ARTICLE; BACTERIAL GROWTH; BACTERICIDAL ACTIVITY; BACTERIUM ISOLATION; CHEMICAL MODIFICATION; CROSS RESISTANCE; DNA ISOLATION; DRUG EFFICACY; DRUG POTENCY; DRUG RESISTANCE; DRUG SCREENING; DRUG STRUCTURE; GRAM POSITIVE BACTERIUM; GROWTH INHIBITION; IC 50; IN VITRO STUDY; MINIMUM INHIBITORY CONCENTRATION; NONHUMAN; PRIORITY JOURNAL; PROTEIN SYNTHESIS; STAPHYLOCOCCUS AUREUS; ACTINOMYCETALES; ANIMAL; ANTIBIOTIC RESISTANCE; CHEMISTRY; COMPARATIVE STUDY; DRUG EFFECT; ISOLATION AND PURIFICATION; MICROBIOLOGICAL EXAMINATION; MOUSE; MUTATION; STAPHYLOCOCCUS INFECTION;

AMYCOLATOPSIS FASTIDIOSA; BACTERIA (MICROORGANISMS); MUS; POSIBACTERIA; STAPHYLOCOCCUS AUREUS;

ACTINOMYCETALES; ANIMALS; ANTI-BACTERIAL AGENTS; DRUG RESISTANCE, BACTERIAL; MICE; MICROBIAL SENSITIVITY TESTS; MUTATION; PEPTIDES; PEPTIDES, CYCLIC; PROTEIN SYNTHESIS INHIBITORS; RNA, RIBOSOMAL; STAPHYLOCOCCAL INFECTIONS; STAPHYLOCOCCUS AUREUS; THIAZOLES;

EID: 38449116767     PISSN: 00218820     EISSN: None     Source Type: Journal    
DOI: 10.1038/ja.2007.71     Document Type: Article

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