The MAP kinase JNK-1 of caenorhabditis elegans: Location, activation, and influences over temperature-dependent insulin-like signaling, stress responses, and fitness

Journal of Cellular Physiology

Volumn 214, Issue 3, 2008, Pages 721-729

  Wolf, Marc ^a   Nunes, Frank ^a   Henkel, Arne ^a   Heinick, Alexander ^a   Paul, Rüdiger J ^a  

^a UNIVERSITY OF MÜNSTER   (Germany)

Author keywords

[No Author keywords available]

Indexed keywords

ENZYME ANTIBODY; GREEN FLUORESCENT PROTEIN; INSULIN; MITOGEN ACTIVATED PROTEIN KINASE; STRESS ACTIVATED PROTEIN KINASE; SUPEROXIDE DISMUTASE; SUPEROXIDE DISMUTASE 3; TRANSCRIPTION FACTOR DAF 16; UNCLASSIFIED DRUG; CAENORHABDITIS ELEGANS PROTEIN; DAF 16 PROTEIN, C ELEGANS; DAF-16 PROTEIN, C ELEGANS; HYDROGEN PEROXIDE; ISOENZYME; JNK 1 PROTEIN, C ELEGANS; JNK-1 PROTEIN, C ELEGANS; TRANSCRIPTION FACTOR;

ARTICLE; CAENORHABDITIS ELEGANS; DELETION MUTANT; ENVIRONMENTAL FACTOR; ENVIRONMENTAL TEMPERATURE; ENZYME ACTIVATION; ENZYME LOCALIZATION; ENZYME PHOSPHORYLATION; GENE TARGETING; HEAT STRESS; HEAT TOLERANCE; NERVE CELL; NONHUMAN; PRIORITY JOURNAL; PROTEIN EXPRESSION; REPRODUCTION; SIGNAL TRANSDUCTION; TEMPERATURE DEPENDENCE; WILD TYPE; ANIMAL; CELL NUCLEUS; CYTOLOGY; DRUG EFFECT; ENZYMOLOGY; GENE DELETION; INTESTINE; METABOLISM; PHYSIOLOGY; PROTEIN TRANSPORT; TEMPERATURE;

CAENORHABDITIS ELEGANS;

ANIMALS; CAENORHABDITIS ELEGANS; CAENORHABDITIS ELEGANS PROTEINS; CELL NUCLEUS; ENZYME ACTIVATION; GENE DELETION; HYDROGEN PEROXIDE; INSULIN; INTESTINES; ISOENZYMES; MITOGEN-ACTIVATED PROTEIN KINASES; PROTEIN TRANSPORT; REPRODUCTION; SIGNAL TRANSDUCTION; SUPEROXIDE DISMUTASE; TEMPERATURE; TRANSCRIPTION FACTORS;

EID: 38449093926     PISSN: 00219541     EISSN: None     Source Type: Journal    
DOI: 10.1002/jcp.21269     Document Type: Article

References (43)

1. Abele D, Puntarulo S. 2004. Formation of reactive species and induction of antioxidant defence systems in polar and temperate marine invertebrates and fish. Comp Biochem Physiol A Mol Integr Physiol 138:405-415.
2. Abele D, Heise K, Poertner HO, Puntarulo S. 2002. Temperature-dependence of mitochondrial function and production of reactive oxygen species in the intertidal mud clam Mya arenaria. J Exp Biol 205:1831-1841.
3. Alcedo J, Kenyon C. 2004. Regulation of C. elegans longevity by specific gustatory and olfactory neurons. Neuron 41:45-55.
4. Apfeld J, Kenyon C. 1999. Regulation of lifespan by sensory perception in Caenorhabditis elegans. Nature 402:804-809.
5. Armstrong GAB, Meldrum Robertson R. 2006. A role for octopamine in coordinating thermoprotection of an insect nervous system. J Thermal Biol 31:149-158.
6. Barsyte D, Lovejoy DA, Lithgow GJ. 2001. Longevity and heavy metal resistance in daf-2 and age-1 long-lived mutants of Caenorhabditis elegans. FASEB J 15:627-634.
7. Brenner S. 1974. The genetics of Caenorhabditis elegans. Genetics 77:71-94.
8. Byrd DT, Kawasaki M, Walcoff M. Hisamoto N, Matsumoto K, Jin Y. 2001. UNC-16, a JNK-signaling scaffold protein, regulates vesicle transport in C. elegans. Neuron 32:787-800.
9. Cobb MH. 1999. MAP kinase pathways. Prog Biophys Mol Biol 71:479-500.
10. Davis RJ. 2000. Signal transduction by the JNK group of MAP kinases. Cell 103:239-252.
11. Garsin DA, Villanueva JM, Begun J, Kim DH, Sifri CD, Calderwood SB, Ruvkun G, Ausubel FM. 2003. Long-lived C. elegans daf-2 mutants are resistant to bacterial pathogens. Science 300:1921.
12. Gems D, McElwee JJ. 2005. Broad spectrum detoxification: The major longevity assurance process regulated by insulin/IGF-1 signaling? Mech Ageing Dev 126:381-3387.
13. Henderson ST, Johnson TE. 2001. daf-16 integrates developmental and environmental inputs to mediate aging in the nematode Caenorhabditis elegans. Curr Biol 11:1975-1980.
14. Hunter T, Bannister WH, Hunter GJ. 1997. Cloning, expression, and characterization of two manganese superoxide dismutases from Caenorhabditis elegans. J Biol Chem 272:28652-28659.
15. Inoue H, Hisamoto N, An JH, Oliveira RP, Nishida E, Blackwell TK, Matsumoto K. 2005. The C. elegans p38 MAPK pathway regulates nuclear localization of the transcription factor SKN-1 in oxidative stress response. Genes Dev 19:2278-2283.
16. Ishii N, Kita K, Hartman PS. 2001. Mitochondrial contributions to aging in the nematode Caenorhabditis elegans. Curr Genomics 2:349-355.
17. Kawasaki M, Hisamoto N. Iino Y, Yamamoto M, Ninomiya-Tsuji J, Matsumoto K. 1999. A Caenorhabditis elegans JNK signal transduction pathway regulates coordinated movement via type-D GABAergic motor neurons. EMBO J 18:3604-3615.
18. Kim DH, Liberati NT. Mizuno T, Inoue H, Hisamoto N, Matsumoto K, Ausubel FM. 2004. Integration of Caenorhabditis elegans MAPK pathways mediating immunity and stress resistance by MEK-1 MAPK kinase and VHP-1 MAPK phosphatase. Proc Natl Acad Sci USA 101:10990-10994.
19. Lamitina ST, Strange K. 2005. Transcriptional targets of DAF-16 insulin signaling pathway protect C. elegans from extreme hypertonic stress. Am J Physiol Cell Physiol 288:467-174.
20. Lin K, Hsin H, Libina N, Kenyon C. 2001. Regulation of the Caenorhabditis elegans longevity protein DAF-16 by insulin/IGF-1 and germline signaling. Nat Genet 28:139-145.
21. Lithgow GJ, Walker GA. 2002. Stress resistance as a determination of C. elegans lifespan. Mech Ageing Dev 123:765-771.
22. Livak KJ, Schmittgen TD. 2001. Analysis of relative gene expression data using real-time quantitative PCR and the 2(-Delta Delta C(T)) Method. Methods 25:402-408.
23. McElwee J, Bubb K. Thomas JH. 2003. Transcriptional outputs of the Caenorhabditis elegans forkhead protein DAF-16. Aging Cell 2:111-121.
24. Mello C, Fire A. 1995. DNA transformation. Methods Cell Biol 48:451-482.
25. Mello C, Kramer JM, Stinchcomb D, Ambros V. 1991. Efficient gene transfer in C. elegans. extrachromosomal maintenance and integration of transforming sequences. EMBO J 10:3959-3970.
26. Melov S, Ravenscroft J, Malik S, Gill MS, Walker DW, Clyton PE, Wallace DC. Malfroy B, Doctrow SR, Lithgow GJ. 2000. Extension of life-span with superoxide dismutase/catalase mimetics. Science 289:1567-1569.
27. Mori I, Ohshima Y. 1995. Neural regulation of thermotaxis in Caenorhabditis elegans. Nature 376:344-348.
28. Murphy CT, McCarroll SA, Bargmann CI, Fraser A, Kamath RS, Ahringer J, Li H, Kenyon C. 2003. Genes that act downstream of DAF-16 to influence the lifespan of Caenorhabditis elegans. Nature 424:277-283.
29. Ogg S, Paradis S, Gottlieb S, Patterson GI, Lee L, Tissenbaum HA, Ruvkun G. 1997. The fork head transcription factor DAF-16 transduces insulin-like metabolic and longevity signals in C. elegans. Nature 389:994-999.
30. Oh SW, Mukhopadhyay A, Svrzikapa N, Jiang F, Davis RJ, Tissenbaum HA. 2005. JNK regulates lifespan in Caenorhabditis elegans by modulating nuclear translocation of forkhead transcription factor/DAF-16. Proc Natl Acad Sci USA 102:4494-4499.
31. Oh S, Mukhopadhyay A, Dixit BL, Raha T, Green MR, Tissenbaum HA. 2006. Identification of direct DAF-16 targets controlling longevity, metabolism and diapause by chromatin immunoprecipitation. Nat Genet 38:251-257.
32. Pearson G, Robinson F, Gibson TB, Xu B, Karandikar M, Berman K, Cobb MH. 2001. Mitogen-activated protein (MAP) kinase pathways: Regulation and physiological functions. Endocr Rev 22:153-183.
33. Perkins LA, Hedgecock EM, Thomson JN, Culotti JG. 1986. Mutant sensory cilia in the nematode Caenorhabditis elegans. Dev Biol 117:456-487.
34. Pierce SB, Costa M, Wisotzkey R, Devadhar S, Homburger SA, Buchman AR, Ferguson KC, Heller J, Platt DM, Pasquinelli AA, Liu LX, Doberstein SK, Ruvkun G. 2001. Regulation of DAF-2 receptor signaling by human insulin and ins-1, a member of the unusually large and diverse C. elegans insulin gene family. Genes Dev 15:672-686.
35. Roeder T. 2005. Tyramine and octopamine: Ruling behavior and metabolism. Annu Rev Entomol 50:447-477.
36. Tsalik EL, Hobert O. 2003. Functional mapping of neurons that control locomotory behavior in Caenorhabditis elegans. J Neurobiol 56:178-197.
37. Vanfleteren JR. 1993. Oxidative stress and ageing in Caenorhabditis elegans. Biochem J 292:605-608.
38. Van Voorhies WA, Ward S. 1999. Genetic and environmental conditions that increase longevity in Caenorhabditis elegans decrease metabolic rate. Proc Natl Acad Sci USA 96:11399-11403.
39. Villanueva A, Lozano J, Morales A, Lin X, Deng X. Hengartner MO, Kolesnick RN. 2001. jkk-1 and mek-1 regulate body movement coordination and response to heavy metals through jnk-1 in Caenorhabditis elegans. EMBO J 20:5114-5128.
40. Wang MC, Bohmann D, Jasper H. 2003. JNK signaling confers tolerance to oxidative stress and extends lifespan in Drosophila. Dev Cell 5:811-816.
41. Wang MC, Bohmann D, Jasper H. 2005. JNK extends life span and limits growth by antagonizing cellular and organism-wide responses to insulin signaling. Cell 121:115-125.
42. Wolkow CA, Kimura KD, Lee MS, Ruvkun G. 2000. Regulation of C. elegans life-span by insulinlike signaling in the nervous system. Science 290:147-150.
43. Yamada Y, Ohshima Y. 2003. Distribution and movement of Caenorhabditis elegans on a thermal gradient. J Exp Biol 206:2581-2593.