Screening anti-inflammatory compounds in injured spinal cord with microarrays: A comparison of bioinformatics analysis approaches

Physiological Genomics

Volumn 17, Issue , 2004, Pages 201-214

  Pan, Jonathan Z ^a   Jörnsten, Rebecka ^b   Hart, Ronald P ^a,b  

^a RUTGERS UNIVERSITY   (United States)

^b RUTGERS UNIVERSITY   (United States)

Author keywords

Clustering analysis; Cyclooxygenase 2; DNA microarrays; Gene expression

Indexed keywords

ANTIINFLAMMATORY AGENT; CATHEPSIN S; CCAAT ENHANCER BINDING PROTEIN; CORTICOSTEROID; CYCLOOXYGENASE 2 INHIBITOR; DECORIN; GENE PRODUCT; HEAT SHOCK PROTEIN 70; INDOMETACIN; INTERLEUKIN 1 RECEPTOR BLOCKING AGENT; MACROPHAGE INFLAMMATORY PROTEIN 1BETA; MACROPHAGE INFLAMMATORY PROTEIN 2; METALLOTHIONEIN; METHYLPREDNISOLONE; MONOCYTE CHEMOTACTIC PROTEIN 1; N (2 CYCLOHEXYLOXY 4 NITROPHENYL)METHANESULFONAMIDE; PARACETAMOL; PLACENTA LACTOGEN; RETINA S ANTIGEN; RIBOSOME PROTEIN; THYMOSIN BETA10; TUMOR NECROSIS FACTOR RECEPTOR; VIMENTIN; CYCLOOXYGENASE 2; CYTOKINE; ISOENZYME; N-(2-CYCLOHEXYLOXY-4-NITROPHENYL)METHANESULFONAMIDE; NITROBENZENE DERIVATIVE; NONSTEROID ANTIINFLAMMATORY AGENT; PROSTAGLANDIN SYNTHASE; PROSTAGLANDIN SYNTHASE INHIBITOR; SULFONAMIDE;

ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; ANTIINFLAMMATORY ACTIVITY; ARTICLE; BIOINFORMATICS; CONTROLLED STUDY; DNA MICROARRAY; GENE CLUSTER; GENE EXPRESSION PROFILING; NEUROPROTECTION; NONHUMAN; NUCLEOTIDE SEQUENCE; PRINCIPAL COMPONENT ANALYSIS; PRIORITY JOURNAL; RAT; REAL TIME POLYMERASE CHAIN REACTION; SPINAL CORD INJURY; STATISTICAL ANALYSIS; TISSUE INJURY; ALGORITHM; ANIMAL; BIOLOGY; CELL CULTURE; CLUSTER ANALYSIS; COMPARATIVE STUDY; CYTOLOGY; DRUG ANTAGONISM; DRUG EFFECT; DRUG SCREENING; EVALUATION; GENE EXPRESSION REGULATION; LONG EVANS RAT; METABOLISM; METHODOLOGY; PATHOLOGY; REVERSE TRANSCRIPTION POLYMERASE CHAIN REACTION; SPINAL CORD;

ANIMALIA;

ALGORITHMS; ANIMALS; ANTI-INFLAMMATORY AGENTS; ANTI-INFLAMMATORY AGENTS, NON-STEROIDAL; CELLS, CULTURED; CLUSTER ANALYSIS; COMPUTATIONAL BIOLOGY; CYCLOOXYGENASE 2; CYCLOOXYGENASE 2 INHIBITORS; CYCLOOXYGENASE INHIBITORS; CYTOKINES; DRUG EVALUATION, PRECLINICAL; GENE EXPRESSION REGULATION; ISOENZYMES; METHYLPREDNISOLONE; NITROBENZENES; OLIGONUCLEOTIDE ARRAY SEQUENCE ANALYSIS; PRINCIPAL COMPONENT ANALYSIS; PROSTAGLANDIN-ENDOPEROXIDE SYNTHASES; RATS; RATS, LONG-EVANS; REVERSE TRANSCRIPTASE POLYMERASE CHAIN REACTION; SPINAL CORD; SPINAL CORD INJURIES; SULFONAMIDES;

EID: 3843141995     PISSN: 15312267     EISSN: None     Source Type: Journal    
DOI: 10.1152/physiolgenomics.00177.2003     Document Type: Article

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