Single molecule force spectroscopy on ligand-DNA complexes: From molecular binding mechanisms to biosensor applications

Journal of Biotechnology

Volumn 112, Issue 1-2, 2004, Pages 5-12

  Ros, Robert ^a   Eckel, Rainer ^a   Bartels, Frank ^a   Sischka, Andy ^a   Baumgarth, Birgit ^a   Wilking, Sven David ^a   Pühler, Alfred ^a   Sewald, Norbert ^a   Becker, Anke ^a   Anselmetti, Dario ^a  

^a BIELEFELD UNIVERSITY   (Germany)

Author keywords

Atomic force microscopy; Ligand DNA interaction; Optical tweezers; Single molecule force spectroscopy

Indexed keywords

BIOSENSORS; CHEMICAL BONDS; COMPLEXATION; DNA; MOLECULAR BIOLOGY; PROTEINS; SPECTROSCOPIC ANALYSIS;

BINDING LIGANDS; DOUBLE-STRANDED (DS) DNA; MOLECULAR BINDING; SINGLE MOLECULE FORCE SPECTROSCOPY (SMFS);

BIOTECHNOLOGY;

DOUBLE STRANDED DNA; LIGAND; PROTEIN;

ATOMIC FORCE MICROSCOPY; BIOSENSOR; CROSS LINKING; DNA PROTEIN COMPLEX; DNA SEQUENCE; ELASTICITY; FORCE; HYSTERESIS; KINETICS; LIGAND BINDING; MELTING POINT; MOLECULAR MECHANICS; NUCLEIC ACID IMMOBILIZATION; PRIORITY JOURNAL; PROTEIN DNA BINDING; SENSITIVITY ANALYSIS; SHORT SURVEY;

BINDING SITES; BIOSENSING TECHNIQUES; DNA; DNA-BINDING PROTEINS; ELASTICITY; LIGANDS; MICROMANIPULATION; MICROSCOPY, ATOMIC FORCE; MOLECULAR BIOLOGY; NUCLEIC ACID CONFORMATION; PHYSICAL STIMULATION; PROTEIN BINDING; PROTEIN CONFORMATION; STRESS, MECHANICAL;

EID: 3843131861     PISSN: 01681656     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.jbiotec.2004.04.029     Document Type: Short Survey

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