Interaction of environmental xenobiotics with a multixenobiotic defense mechanism in the bay mussel Mytilus galloprovincialis from the coast of California

Environmental Toxicology and Chemistry

Volumn 15, Issue 3, 1996, Pages 325-331

  Galgani, Francois ^a   Cornwall, Roger ^b   Toomey, Barbara Holland ^b   Epel, David D ^b  

^a IFREMER   (France)

^b STANFORD UNIVERSITY   (United States)

Author keywords

Multidrug resistance; Multixenobiotic transport; Mussel; P glycoprotein; Xenobiotic

Indexed keywords

ENVIRONMENTAL CHEMICAL; XENOBIOTIC AGENT;

ARTICLE; CHEMICAL ANALYSIS; MUSSEL; NONHUMAN; PRIORITY JOURNAL; PROTEIN ANALYSIS; SEASHORE; WATER POLLUTANT; WATER POLLUTION; XENOBIOTIC METABOLISM;

MAMMALIA; MYTILUS GALLOPROVINCIALIS;

EID: 0030053023     PISSN: 07307268     EISSN: None     Source Type: Journal    
DOI: 10.1897/1551-5028(1996)015<0325:IOEXWA>2.3.CO;2     Document Type: Article

References (24)

1. Stegeman, J.J., M. Brouwer, R.T. Di Giulio, L. Forlin, B.A. Fowler, B.M. Sanders and P.A. Van Veld. 1992. Molecular responses to environmental contamination: Enzyme and protein systems as indicators of chemical exposure and effect. In R. Huggett, R.A. Kimerle, P.M. Mehrle, Jr. and H.L. Bergman, eds., Biomarkers: Biochemical, Physiological, and Histological Markers of Anthropogenic Stress. Lewis, Boca Raton, FL, USA, pp. 235-335
2. Endicott, J.A. and V. Ling. 1989. The biochemistry of P-glycoprotein-mediated multidrug resistance. Annu. Rev. Biochem. 58: 137-171.
3. Gottesman, M.M. and I. Pastan. 1993. Biochemistry of multidrug resistance mediated by the multidrug transporter. Annu. Rev Biochem. 62:385-427.
4. Hofsli, E. and J. Nissen-Meyer. 1990. Reversal of multidrug resistance by lipophilic drugs. Cancer Res. 50:3997-4002.
5. Pearce, H.L., M.A. Winter and W.T. Beck. 1990. Structural characteristics of compounds that modulate P-glycoprotein-associated multidrug resistance. Adv. Enzyme Regul. 30:357-373.
6. Ames, F.-L.G. and H. Lecar. 1992. ATP-dependent bacterial transporters and cystic fibrosis: Analogy between channels and transporters. FASEB J. 6:2660-2666.
7. McGrath, J.P. and A. Varshavsky. 1989. The yeast STE6 gene encodes a homologue of the mammalian multidrug resistance P-glycoprotein. Nature 340:400-404.
8. Kurelec, B. 1992. The multixenobiotic resistance mechanism in aquatic organisms. Crit. Rev. Toxicol. 22:23-43.
9. Waldmann, P., B. Pivcevic, W.E.G. Mueller, R.K. Zahn and B. Kurelec. 1995. Increased genotoxicity of acetylaminofluorene by modulators of multixenobiotic resistance mechanism: Studies with the fresh water clam Corbicula fluminea. Mutat. Res. 342:113-123.
10. Toomey, B.H. and D. Epel. 1993. Multixenobiotic resistance in Urechis caupo embryos: Protection from environmental toxins. Biol. Bull. 185:355-364.
11. Minier, C., F. Akcha and F. Galgani. 1993. P-glycoprotein expression in Crassostrea gigas and Mytilus edulis in polluted sea water. Comp. Biochem. Physiol. B 106:1029-1036.
12. Cornwall, R., B.H. Toomey, S. Bard, C. Bacon, W.M. Jarman and D. Epel. 1995. Characterization of multixenobiotic/multidrug transport in the gills of the mussel Mytilus californianus and identification of environmental substrates. Aquat. Toxicol. 31:277-296.
13. Kurelec, B., S. Krca, B. Pivcevic, D. Ugarkovic, M. Bachmann, G. Imsiecke and W.E.G. Muller. 1992. Expression of P-glycoprotein gene in marine sponges: Identification of the 125 kDa drug-binding glycoprotein. Carcinogenesis 13:69-76.
14. Neyfakh, A.A. 1988. Use of fluorescent dyes as molecular probes for the study of multidrug resistance. Exp. Cell Res. 174:168-176.
15. Laemmli, U.K. 1968. Cleavage of structural proteins during the assembly of the head bacteriophage T4. Nature 227:680-685.
16. Towbin, H.T., T. Staehelin and J. Gordon. 1979. Electrophoretic transfer of proteins from polyacrylamide gels to nitrocellulose sheets. Procedure and some applications. Proc. Natl. Acad. Sci. U.S.A. 76:4350-4354.
17. Georges, E., G. Bradley, J. Gariepy and V. Ling. 1990. Detection of P-glycoprotein isoforms by gene-specific monoclonal antibodies. Proc. Natl. Acad. Sci. U.S.A. 87:152-156.
18. Hawkes, R., E. Niday and J. Gordon. 1982. Dot-immunobinding assay for monoclonal and other antibodies. Anal. Biochem. 119: 142-147.
19. Kurelec, B. and B. Pivcevic. 1991. Evidence for a multixenobiotic resistance mechanism in the mussel Mytilus galloprovincialis. Aquat. Toxicol. 19:291-302.
20. Toomey, B.H. and D. Epel. A multixenobiotic transporter in Urechis caupo embryos: Protection from pesticides? Mar. Environ. Res. 39:299-303,
21. Phillips, P.T. 1988. California state mussel watch: Ten-year data summary 1977-1987. Water Quality Monitoring Report 87-3. California State Water Resources Control Board, Sacramento, CA, USA.
22. Claisse, D. 1989. Chemical contamination of French coasts: The results of ten years mussel watch. Mar. Pollut. Bull. 20:523-528.
23. Fowler, S.W. 1990. Critical review of selected heavy metal and chlorinated hydrocarbon concentrations in the marine environment. Mar. Environ. Res. 29:1-64.
24. Kurelec, B., S. Krca and D. Lucie. 1996. Expression of multixenobiotic resistance mechansim in a marine mussel Mytilus galloprovincialis as a biomarker of exposure to polluted environments. Comp. Biochem. Physiol. (in press).