Hepatic cell-specific ATP-binding cassette (ABC) transporter profiling identifies putative novel candidates for lipid homeostasis in mice

Atherosclerosis

Volumn 196, Issue 2, 2008, Pages 650-658

  Ye, Dan ^a   Hoekstra, Menno ^a   Out, Ruud ^a   Meurs, Illiana ^a   Kruijt, J Kar ^a   Hildebrand, Reeni B ^a   Van Berkel, Theo J C ^a   Van Eck, Miranda ^a  

^a LEIDEN UNIVERSITY   (Netherlands)

Author keywords

ABC transporters; Macrophages cholesterol homeostasis; Mouse models

Indexed keywords

ABC TRANSPORTER; ABC TRANSPORTER A13; ABC TRANSPORTER A4; ABC TRANSPORTER A5; ABC TRANSPORTER A6; ABC TRANSPORTER A8; ABC TRANSPORTER A9; ABC TRANSPORTER B10; ABC TRANSPORTER B11; ABC TRANSPORTER B2; ABC TRANSPORTER B8; ABC TRANSPORTER B9; ABC TRANSPORTER C1; ABC TRANSPORTER C3; ABC TRANSPORTER C5; ABC TRANSPORTER D2; ABC TRANSPORTER D3; ABC TRANSPORTER D4; ABC TRANSPORTER F2; ABC TRANSPORTER G1; ABC TRANSPORTER G4; ABC TRANSPORTER G5; ABC TRANSPORTER G8; CHOLESTEROL; FAT; LIVER PROTEIN; MESSENGER RNA; MULTIDRUG RESISTANCE PROTEIN 1; UNCLASSIFIED DRUG;

ANIMAL CELL; ANIMAL TISSUE; ARTICLE; CHOLESTEROL DIET; CHOLESTEROL METABOLISM; CONTROLLED STUDY; DIET SUPPLEMENTATION; GENE EXPRESSION; HOMEOSTASIS; KUPFFER CELL; LIPID DIET; LIVER CELL; LIVER PARENCHYMA; MALE; MOUSE; NONHUMAN; NUCLEOTIDE SEQUENCE; PRIORITY JOURNAL; REVERSE TRANSCRIPTION POLYMERASE CHAIN REACTION;

ANIMALS; ATP-BINDING CASSETTE TRANSPORTERS; CHOLESTEROL; DIET; GENE EXPRESSION PROFILING; HOMEOSTASIS; KUPFFER CELLS; LIPID METABOLISM; LIVER; MALE; MICE;

EID: 38349191048     PISSN: 00219150     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.atherosclerosis.2007.07.021     Document Type: Article

References (37)

1. Higgins C.F. ABC transporters: from microorganisms to man. Annu Rev Cell Biol 8 (1992) 67-113
2. Dean M., Hamon Y., and Chimini G. The human ATP-binding cassette (ABC) transporter superfamily. J Lipid Res 42 (2001) 1007-1017
3. Rye K.A., and Barter P.J. Formation and metabolism of prebeta-migrating, lipid-poor apolipoprotein A-I. Arterioscler Thromb Vasc Biol 24 (2004) 421-428
4. Klucken J., Buchler C., Orso E., et al. ABCG1 (ABC8), the human homolog of the Drosophila white gene, is a regulator of macrophage cholesterol and phospholipid transport. Proc Natl Acad Sci USA 97 (2000) 817-822
5. Jessup W., Gelissen I.C., Gaus K., et al. Roles of ATP binding cassette transporters A1 and G1, scavenger receptor BI and membrane lipid domains in cholesterol export from macrophages. Curr Opin Lipidol 17 (2006) 247-257
6. Kennedy M.A., Barrera G.C., Nakamura K., et al. ABCG1 has a critical role in mediating cholesterol efflux to HDL and preventing cellular lipid accumulation. Cell Metab 1 (2005) 121-131
7. Wang N., Lan D., Chen W., et al. ATP-binding cassette transporters G1 and G4 mediate cellular cholesterol efflux to high-density lipoproteins. Proc Natl Acad Sci USA 101 (2004) 9774-9779
8. Graf G.A., Li W.P., Gerard R.D., et al. Coexpression of ATP-binding cassette proteins ABCG5 and ABCG8 permits their transport to the apical surface. J Clin Invest 110 (2002) 659-669
9. Szakacs G., Annereau J.P., Lababidi S., et al. Predicting drug sensitivity and resistance: profiling ABC transporter genes in cancer cells. Cancer Cell 6 (2004) 129-137
10. Dean M., Rzhetsky A., and Allikmets R. The human ATP-binding cassette (ABC) transporter superfamily. Genome Res 11 7 (2001) 1156-1166
11. Lawn R.M., Wade D.P., Garvin M.R., et al. The Tangier disease gene product ABC1 controls the cellular apolipoprotein-mediated lipid removal pathway. J Clin Invest 104 (1999) R25-R31
12. Lorkowski S., Kratz M., Wenner C., et al. Expression of the ATP-binding cassette transporter gene ABCG1 (ABC8) in Tangier disease. Biochem Biophys Res Commun 283 4 (2001) 821-830
13. Hubacek J.A., Berge K.E., Cohen J.C., et al. Mutations in ATPcassette binding proteins G5 (ABCG5) and G8 (ABCG8) causing sitosterolemia. Hum Mutat 18 (2001) 359-360
14. Berge K.E., Tian H., Graf G.A., et al. Accumulation of dietary cholesterol in sitosterolemia caused by mutations in adjacent ABC transporters. Science 290 (2000) 1771-1775
15. Langmann T., Mauerer R., and Schmitz G. Human ATP-binding cassette transporter TaqMan low-density array: analysis of macrophage differentiation and foam cell formation. Clin Chem 52 2 (2006) 310-313
16. Hoekstra M., Kruijt J.K., Van Eck M., et al. Specific gene expression of ATP-binding cassette transporters and nuclear hormone receptors in rat liver parenchymal, endothelial, and Kupffer cells. J Biol Chem 278 (2003) 25448-25453
17. Out R., Hoekstra M., Meurs I., et al. Total body ABCG1 expression protects against early atherosclerotic lesion development in mice. Arterioscler Thromb Vasc Biol 27 3 (2007) 594-599
18. Van Velzen A.G., Da Silva R.P., Gordon S., et al. Characterization of a receptor for oxidized low-density lipoproteins on rat Kupffer cells: similarity to macrosialin. Biochem J 322 (1997) 411-415
19. Chomczynski P., and Sacchi N. Single-step method of RNA isolation by acid guanidinium thiocyanate-phenol-chloroform extraction. Anal Biochem 162 (1987) 156-159
20. Smit J.J., Schinkel A.H., Oude Elferink R.P., et al. Homozygous disruption of the murine mdr2 P-glycoprotein gene leads to a complete absence of phospholipid from bile and to liver disease. Cell 75 (1993) 451-462
21. Langheim S., Yu L., von Bergmann K., et al. ABCG5 and ABCG8 require MDR2 for secretion of cholesterol into bile. J Lipid Res 46 (2005) 1732-1738
22. Maisonnette F., Abita T., Barriere E., et al. The MDR3 gene mutation: a rare cause of progressive familial intrahepatic cholestasis (PFIC). Ann Chir 130 (2005) 581-583
23. Wakabayashi Y., Lippincott-Schwartz J., and Arias I.M. Intracellular trafficking of bile salt export pump (ABCB11) in polarized hepatic cells: constitutive cycling between the canalicular membrane and rab11-positive endosomes. Mol Biol Cell 15 (2004) 3485-3496
24. Thompson R., and Strautnieks S. BSEP: function and role in progressive familial intrahepatic cholestasis. Semin Liver Dis 21 (2001) 545-550
25. Hashimoto K., Uchiumi T., Konno T., et al. Trafficking and functional defects by mutations of the ATP-binding domains in MRP2 in patients with Dubin-Johnson syndrome. Hepatology 36 (2002) 1236-1245
26. Bakkeren H.F., Kuipers F., Vonk R.J., et al. Evidence for reverse cholesterol transport in vivo from liver endothelial cells to parenchymal cells and bile by high-density lipoprotein. Biochem J 268 3 (1990) 685-691
27. Blomhoff R., Drevon C.A., Eskild W., et al. Clearance of acetyl low density lipoprotein by rat liver endothelial cells. J Biol Chem 259 14 (1984) 8896-8903
28. Pennings M., Meurs I., Ye D., et al. Regulation of cholesterol homeostasis in macrophages and consequences for atherosclerotic lesion development. FEBS Lett 580 23 (2006) 5588-5596
29. Van Eck M., Pennings M., Hoekstra M., et al. Scavenger receptor BI and ATP-binding cassette transporter A1 in reverse cholesterol transport and atherosclerosis. Curr Opin Lipidol 16 (2005) 307-315
30. Neufeld E.B., Demosky Jr. S.J., Stonik J.A., et al. The ABCA1 transporter functions on the basolateral surface of hepatocytes. Biochem Biophys Res Commun 297 (2002) 974-979
31. Wanders R.J., Visser W.F., van Roermund C.W., et al. The peroxisomal ABC transporter family. Pflugers Arch 453 (2007) 719-734
32. Fourcade S., Savary S., Albet S., et al. Fibrate induction of the adrenoleukodystrophy-related gene (ABCD2): promoter analysis and role of the peroxisome proliferator-activated receptor PPARalpha. Eur J Biochem 268 (2001) 3490-3500
33. Chinetti G., Fruchart J.C., and Staels B. Transcriptional regulation of macrophage cholesterol trafficking by PPARalpha and LXR. Biochem Soc Trans 34 (2006) 1128-1131
34. Kubo Y., Sekiya S., Ohigashi M., et al. ABCA5 resides in lysosomes, and ABCA5 knockout mice develop lysosomal disease-like symptoms. Mol Cell Biol 25 (2005) 4138-4149
35. Petry F., Ritz V., Meineke C., et al. Subcellular localization of rat Abca5, a rat ATP-binding-cassette transporter expressed in Leydig cells, and characterization of its splice variant apparently encoding a half-transporter. Biochem J 393 (2006) 79-87
36. Chen W., Wang N., and Tall A.R. A PEST deletion mutant of ABCA1 shows impaired internalization and defective cholesterol efflux from late endosomes. J Biol Chem 280 (2005) 29277-29281
37. Neufeld E.B., Stonik J.A., Demosky Jr. S.J., et al. The ABCA1 transporter modulates late endocytic trafficking: insights from the correction of the genetic defect in Tangier disease. J Biol Chem 279 (2004) 15571-15578