Hygroscopicity, phase solubility and dissolution of various substituted sulfobutylether β-cyclodextrins (SBE) and danazol-SBE inclusion complexes

International Journal of Pharmaceutics

Volumn 212, Issue 2, 2001, Pages 177-186

  Jain, Ashwinkumar C ^a   Adeyeye, Moji Christianah ^a  

^a DUQUESNE UNIVERSITY   (United States)

Author keywords

Danazol; Differential scanning calorimetry; Dissolution; Inclusion complexes; Moisture sorption desorption isotherms; Phase solubility analysis; Porosity; Sulfobutylether cyclodextrins (SBE); Surface area analysis; X ray diffraction

Indexed keywords

BETA CYCLODEXTRIN DERIVATIVE; BETA CYCLODEXTRIN SULFOBUTYL ETHER; DANAZOL; ITRACONAZOLE;

ARTICLE; CRYSTAL STRUCTURE; DIFFERENTIAL SCANNING CALORIMETRY; DISSOLUTION; DRUG SCREENING; DRUG SOLUBILITY; HYSTERESIS; PARTICLE SIZE; PRIORITY JOURNAL; STOICHIOMETRY; WETTABILITY;

BETA-CYCLODEXTRINS; CALORIMETRY, DIFFERENTIAL SCANNING; CYCLODEXTRINS; DANAZOL; SOLUBILITY; THERMODYNAMICS; WETTABILITY; X-RAY DIFFRACTION;

EID: 0035895308     PISSN: 03785173     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0378-5173(00)00607-4     Document Type: Article

References (18)

1. Hygroscopicity and stability of danazol-hydrophilic cyclodextrin inclusion complex
2. The molecular basis of moisture effects on the physical and chemical stability of drugs in solid state
3. A study of the complexation between danazol and hydrophilic cyclodextrin derivatives
4. Phase solubility techniques
5. β-cyclodextrin derivatives, SBE 4-β-CD and HP-β-CD, increase the oral bioavailability of cinnarizine in beagle dogs
6. Fractionation and characterization of 4-sulfobutyl ether derivatives of cyclomaltoheptaose (β-cyclodextrin)
7. Isolation and characterization by NMR spectroscopy of three monosubstituted 4-sulfobutyl ether derivatives of cyclomaltoheptaose (β-cyclodextrin)
8. Solubilization of drugs by modified β-cyclodextrins
9. The interaction of charged and uncharged drugs with neutral (HP β-CD) and anionically charged (SBE 7 β-CD) β-cyclodextrin
10. Characterization of β-cyclodextrin for direct compression tabeleting: II. The role of moisture in the compactibility of β-cyclodextrin
11. Cyclodextrins-enabling excipients: Their present and future use in pharmaceuticals
12. Stability studies on steroidal drug/β-cyclodextrin kneaded system
13. Improvement of water solubility and dissolution rate of ursodeoxycholic acid and chenodeoxycholic acid by complexation with natural and modified β-cyclodextrins
14. The improvement of the solubility and stability of compound A in sulphoalkyl ether derivatives of β-cyclodextrin solutions. I. Feasibility study
15. Effect of alkyl chain length and degree of substitution on the complexation of sulfoalkyl ether β cyclodextrin