Localization and control of expression of VEGF-A and the VEGFR-2 receptor in fetal sheep intestines

Pediatric Research

Volumn 63, Issue 2, 2008, Pages 143-148

  Holmes, Katrina ^a   Charnock Jones, Stephen D ^a   Forhead, Alison J ^a   Giussani, Dino A ^a   Fowden, Abigail L ^a   Licence, Diana ^a   Kempster, Sarah ^a   Smith, Gordon C S ^a  

^a UNIVERSITY OF CAMBRIDGE   (United Kingdom)

Author keywords

[No Author keywords available]

Indexed keywords

HYDROCORTISONE; VASCULOTROPIN A; VASCULOTROPIN RECEPTOR 2;

ADRENALECTOMY; ANIMAL EXPERIMENT; ANIMAL TISSUE; ARTICLE; CONTROLLED STUDY; EPITHELIUM CELL; FETUS; GESTATIONAL AGE; IN SITU HYBRIDIZATION; INTESTINE VILLUS; LAMINA PROPRIA; NONHUMAN; PREMATURITY; PRIORITY JOURNAL; PROTEIN BINDING; PROTEIN EXPRESSION; PROTEIN FUNCTION; PROTEIN LOCALIZATION; SHEEP; SMALL INTESTINE; UPREGULATION;

ANIMALS; GENE EXPRESSION REGULATION, DEVELOPMENTAL; GLUCOCORTICOIDS; HYDROCORTISONE; IMMUNOHISTOCHEMISTRY; IN SITU HYBRIDIZATION; INTESTINES; MODELS, BIOLOGICAL; RNA, MESSENGER; SHEEP; SHEEP, DOMESTIC; UP-REGULATION; VASCULAR ENDOTHELIAL GROWTH FACTOR A; VASCULAR ENDOTHELIAL GROWTH FACTOR RECEPTOR-2;

EID: 38349125416     PISSN: 00313998     EISSN: None     Source Type: Journal    
DOI: 10.1203/PDR.0b013e31815f00e0     Document Type: Article

References (18)

1. Caplan MS 2004 Pathophysiology and prevention of neonatal necrotizing enterocolitis. In: Polin RA, Fox WH, Abman SH (eds) Fetal and Neonatal Physiology. Saunders, Philadelphia, pp 1169-1174
2. Trahair JF, Sangild PT 1997 Systemic and luminal influences on the perinatal development of the gut. Equine Vet J Suppl:40-50
3. Ferrara N, Gerber HP, LeCouter J 2003 The biology of VEGF and its receptors. Nat Med 9:669-676
4. Mostyn A, Pearce S, Budge H, Elmes M, Forhead AJ, Fowden AL, Stephenson T, Symonds ME 2003 Influence of cortisol on adipose tissue development in the fetal sheep during late gestation. J Endocrinol 176:23-30
5. Fowden AL, Szemere J, Hughes P, Gilmour RS, Forhead AJ 1996 The effects of cortisol on the growth rate of the sheep fetus during late gestation. J Endocrinol 151:97-105
6. Fowden AL, Mijovic J, Silver M 1993 The effects of cortisol on hepatic and renal gluconeogenic enzyme activities in the sheep fetus during late gestation. J Endocrinol 137:213-222
7. Ward JW, Forhead AJ, Wooding FB, Fowden AL 2006 Functional significance and cortisol dependence of the gross morphology of ovine placentomes during late gestation. Biol Reprod 74:137-145
8. Robinson PM, Comline RS, Fowden AL, Silver M 1983 Adrenal cortex of fetal lamb: changes after hypophysectomy and effects of Synacthen on cytoarchitecture and secretory activity. Q J Exp Physiol 68:15-27
9. Redmer DA, Dai Y, Li J, Charnock-Jones DS, Smith SK, Reynolds LP, Moor RM 1996 Characterization and expression of vascular endothelial growth factor (VEGF) in the ovine corpus luteum. J Reprod Fertil 108:157-165
10. Clark DE, Smith SK, Sharkey AM, Charnock-Jones DS 1996 Localization of VEGF and expression of its receptors flt and KDR in human placenta throughout pregnancy. Hum Reprod 11:1090-1098
11. Shweiki D, Itin A, Neufeld G, Gitay-Goren H, Keshet E 1993 Patterns of expression of vascular endothelial growth factor (VEGF) and VEGF receptors in mice suggest a role in hormonally regulated angiogenesis. J Clin Invest 91:2235-2243
12. Fowden AL, Forhead AJ 2004 Endocrine mechanisms of intrauterine programming. Reproduction 127:515-526
13. Charnock-Jones DS, Clark DE, Licence D, Day K, Wooding FB, Smith SK 2001 Distribution of vascular endothelial growth factor (VEGF) and its binding sites at the maternal-fetal interface during gestation in pigs. Reproduction 122:753-760
14. Gerber HP, Hillan KJ, Ryan AM, Kowalski J, Keller GA, Rangell L, Wright BD, Radtke F, Aguet M, Ferrara N 1999 VEGF is required for growth and survival in neonatal mice. Development 126:1149-1159
15. Siafakas CG, Anatolitou F, Fusunyan RD, Walker WA, Sanderson IR 1999 Vascular endothelial growth factor (VEGF) is present in human breast milk and its receptor is present on intestinal epithelial cells. Pediatr Res 45:652-657
16. Bikfalvi A, Bicknell R 2002 Recent advances in angiogenesis, anti-angiogenesis and vascular targeting. Trends Pharmacol Sci 23:576-582
17. Chandler JC, Hebra A 2000 Necrotizing enterocolitis in infants with very low birth weight. Semin Pediatr Surg 9:63-72
18. Roberts D, Dalziel S 2006 Antenatal corticosteroids for accelerating fetal lung maturation for women at risk of preterm birth. Cochrane Database Syst Rev 3:CD004454