Fish-oil supplementation in patients with implantable cardioverter defibrillators: A meta-analysis

CMAJ. Canadian Medical Association Journal

Volumn 178, Issue 2, 2008, Pages 157-164

  Jenkins, David J A ^a,b   Josse, Andrea R ^a,b   Beyene, Joseph ^b   Dorian, Paul ^a   Burr, Michael L ^c   LaBelle, Roxanne ^a,b   Kendall, Cyril W C ^a,b   Cunnane, Stephen C ^d  

^a ST MICHAEL'S HOSPITAL   (Canada)

^b UNIVERSITY OF TORONTO   (Canada)

^c CARDIFF UNIVERSITY   (United Kingdom)

^d UNIVERSITY INSTITUTE OF GERIATRICS OF SHERBROOKE   (Canada)

Author keywords

[No Author keywords available]

Indexed keywords

AMIODARONE; BETA ADRENERGIC RECEPTOR BLOCKING AGENT; CALCIUM CHANNEL BLOCKING AGENT; DIGOXIN; DIPEPTIDYL CARBOXYPEPTIDASE INHIBITOR; DIURETIC AGENT; FISH OIL; HYDROXYMETHYLGLUTARYL COENZYME A REDUCTASE INHIBITOR; SOTALOL;

ARTICLE; CINAHL; CLINICAL TRIAL; COCHRANE LIBRARY; CONFIDENCE INTERVAL; DEFIBRILLATOR; EMBASE; FOLLOW UP; HEART VENTRICLE FIBRILLATION; HEART VENTRICLE TACHYCARDIA; HUMAN; IMPLANTATION; LOG RANK TEST; MANTEL HAENSZEL TEST; MEDLINE; META ANALYSIS; RISK FACTOR; STATISTICAL SIGNIFICANCE; SYSTEMATIC REVIEW; TREATMENT OUTCOME; VITAMIN SUPPLEMENTATION;

EID: 38349090537     PISSN: 08203946     EISSN: 14882329     Source Type: Journal    
DOI: 10.1503/cmaj.070261     Document Type: Article

References (46)

1. CBC News. Contaminated fish? Benefits outweigh the risks. Toronto: Canadian Broadcasting Corporation; 2007. Available: www.cbc.ca/news/background/ food-safety/fish.html (accessed 2007 Aug 15).
2. BBC.co.uk. Guidance on oily fish consumption. London (UK): BBC; 2004. Available: news.bbc.co.uk/1/hi/health/3834955.stm (accessed 2007 Aug 15).
3. Barton A. How flawed is your fish? Globe and Mail [Toronto] 2007. Available: www.theglobeandmail.com/servlet/story/RTGAM.20070516.wxlfish16/ BNStory/GlobeSportsHockey/ (accessed 2007 Nov 20).
4. Hooper L, Thompson RL, Harrison RA, et al. Risks and benefits of omega-3 fats for mortality, cardiovascular disease and cancer: systematic review. BMJ 2006;332:752-60.
5. Mozaffarian D, Rimm EB. Fish intake, contaminants and human health: evaluating the risks and the benefits. JAMA 2006;296:1885-99.
6. Kris-Etherton PM, Harris WS, Appel LJ. Fish consumption, fish oil, omega-3 fatty acids and cardiovascular disease. Circulation 2002;106:2747-57.
7. Buettner C, Phillips RS, Davis RB, et al. Use of dietary supplements among United States adults with coronary artery disease and atherosclerotic risks. Am J Cardiol 2007;99:661-6.
8. FOOD productiondaily.com. Global fish oil production down in 2005. France: Decision News Media; 2006. Available: www.foodproductiondaily.com/news/ ng.asp?id=66435-fish-oil-omega (accessed 2007 Aug 15).
9. National Oceanic and Atmospheric Administration Fisheries: Office of Science and Technology. Quarterly fish meal and oil production (first quarter). Washington: US Census Bureau; 2007. Available: www.st.nmfs.gov/st1/market_news/ doc76.txt (accessed 2007 Aug 15).
10. Balk EM, Lichtenstein AH, Chung M, et al. Effects of omega-3 fatty acids on coronary restenosis, intima-media thickness, and exercise tolerance: a systematic review. Atherosclerosis 2006; 184:237-46.
11. Leaf A, Jorgensen MB, Jacobs AK, et al. Do fish oils prevent restenosis after coronary angioplasty? Circulation 1994;90:2248-57.
12. Raitt MH, Connor WE, Morris C, et al. Fish oil supplementation and risk of ventricular tachycardia and ventricular fibrillation in patients with implantable defibrillators: a randomized controlled trial. JAMA 2005;293:2884-91.
13. Leaf A, Albert CM, Josephson M, et al. Prevention of fatal arrhythmias in high-risk subjects by fish oil n-3 fatty acid intake. Circulation 2005;112:2762-8.
14. Brouwer IA, Zock PL, Camm AJ, et al. Effect of fish oil on ventricular tachyarrhythmia and death in patients with implantable cardioverter defibrillators: the Study on Omega-3 Fatty Acids and Ventricular Arrhythmia (SOFA) randomized trial. JAMA 2006;295:2613-9.
15. Jadad AR, Moore RA, Carroll D, et al. Assessing the quality of reports of randomized clinical trials: is blinding necessary? Control Clin Trials 1996;17:1-12.
16. DerSimonian R, Laird N. Meta-analysis in clinical trials. Control Clin Trials 1986;7: 177-88.
17. Higgins JP, Thompson SG, Deeks JJ, et al. Measuring inconsistency in meta-analyses. BMJ 2003;327:557-60.
18. Brouwer IA, Zock PL, Wever EF, et al. Rationale and design of a randomised controlled clinical trial on supplemental intake of n-3 fatty acids and incidence of cardiac arrhythmia: SOFA. Eur J Clin Nutr 2003;57:1323-30.
19. I have an implantable cardioverter defibrillator (ICD), and I've been taking fish oil supplements because I had heard of their potential heart benefits. However, I recently read they might not be safe for people with ICDs. Should I stop taking them? Johns Hopkins Med Lett Health After 50 2005;17:8.
20. Brouwer IA, Geelen A, Katan MB. n-3 Fatty acids, cardiac arrhythmia and fatal coronary heart disease. Prog Lipid Res 2006;45:357-67.
21. Jacobson TA. Secondary prevention of coronary artery disease with omega-3 fatty acids. Am J Cardiol 2006;98:61i-70i.
22. Cleland JG, Coletta AP, Lammiman M, et al. Clinical trials update from the European Society of Cardiology meeting 2005: CARE-HF extension study, ESSENTIAL, CIBIS-III, S-ICD, ISSUE-2, STRIDE-2, SOFA, IMAGINE, PREAMI, SIRIUS-II and ACTIVE. Eur J Heart Fail 2005;7:1070-5.
23. Macchia A, Levantesi G, Franzosi MG, et al. Left ventricular systolic dysfunction, total mortality, and sudden death in patients with myocardial infarction treated with n-3 polyunsaturated fatty acids. Eur J Heart Fail 2005;7:904-9.
24. Burr ML, Ashfield-Watt PA, Dunstan FD, et al. Lack of benefit of dietary advice to men with angina: results of a controlled trial. Eur J Clin Nutr 2003;57:193-200.
25. Burr ML, Dunstan FD, George CH. Is fish oil good or bad for heart disease? Two trials with apparendy conflicting results. J Membr Biol 2005;206:155-63.
26. GISSI-Prevenzione. Dietary supplementation with n-3 polyunsaturated fatty acids and vitamin E after myocardial infarction: results of the GISSI-Prevenzione trial. Gruppo Italiano per lo Studio della Sopravvivenza nell'Infarto miocardico. Lancet 1999;354:447-55.
27. Burr ML, Fehily AM, Gilbert JF, et al. Effects of changes in fat, fish, and fibre intakes on death and myocardial reinfarction: diet and reinfarction trial (DART). Lancet 1989;2:757-61.
28. Yokoyama M, Origasa H, Matsuzaki M, et al. Effects of eicosapentaenoic acid on major coronary events in hypercholesterolaemic patients (JELIS): a randomised open-label, blinded endpoint analysis. Lancet 2007;369:1090-8.
29. Leaf A. Prevention of sudden cardiac death by n-3 polyunsaturated fatty acids. Fundam Clin Pharmacol 2006;20:525-38.
30. Leaf A. Omega-3 fatty acids and prevention of arrhythmias. Curr Opin Lipidol 2007;18:31-4.
31. Marchioli R, Barzi F, Bomba E, et al. Early protection against sudden death by n-3 polyunsaturated fatty acids after myocardial infarction: time-course analysis of the results of the Gruppo Italiano per lo Studio della Sopravvivenza nell'Infarto Miocardico (GlSSI)-Prevenzione. Circulation 2002;105:1897-903.
32. de Lorgeril M, Renaud S, Mamelle N, et al. Mediterranean alpha-linolenic acid-rich diet in secondary prevention of coronary heart disease. Lancet 1994;343:1454-9.
33. Shepherd J, Cobbe SM, Ford I, et al. Prevention of coronary heart disease with pravastatin in men with hypercholesterolemia. West of Scotland Coronary Prevention Study Group. N Engl J Med 1995;333:1301-7.
34. Downs JR, Clearfield M, Weis S, et al. Primary prevention of acute coronary events with lovastatin in men and women with average cholesterol levels: results of AFCAPS/TexCAPS. Air Force/Texas Coronary Atherosclerosis Prevention Study. JAMA 1998;279:1615-22.
35. Geelen A, Brouwer IA, Schouten EG, et al. Effects of n-3 fatty acids from fish on premature ventricular complexes and heart rate in humans. Am J Clin Nutr 2005;81:416-20.
36. Geelen A, Zock PL, Brouwer IA, et al. Effect of n-3 fatty acids from fish on electrocardiographic characteristics in patients with frequent premature ventricular complexes. Br J Nutr 2005;93:787-90.
37. Hardarson T, Kristinsson A, Skuladottir G, et al. Cod liver oil does not reduce ventricular extrasystoles after myocardial infarction. J Intern Med 1989;226:33-7.
38. Christensen JH, Gustenhoff P, Korup E, et al. Effect of fish oil on heart rate variability in survivors of myocardial infarction: a double blind randomised controlled trial. BMJ 1996;312:677-8.
39. Mozaffarian D, Geelen A, Brouwer IA, et al. Effect of fish oil on heart rate in humans: a meta-analysis of randomized controlled trials. Circulation 2005;112:1945-52.
40. O'Keefe JH Jr, Abuissa H, Sastre A, et al. Effects of omega-3 fatty acids on resting heart rate, heart rate recovery after exercise, and heart rate variability in men with healed myocardial infarctions and depressed ejection fractions. Am J Cardiol 2006;97:1127-30.
41. Lau J, Ioannidis JP, Schmid CH. Quantitative synthesis in systematic reviews. Ann Intern Med 1997;127:820-6.
42. Laurent G, Moe G, Hu X, et al. Long chain n-3 polyunsaturated fatty acids reduce atrial vulnerability in a novel canine pacing model. Cardiovasc Res 2007 Epub 2007 Oct 21 ahead of print.
43. Bays H. Clinical overview of Omacor: a concentrated formulation of omega-3 polyunsaturated fatty acids. Am J Cardiol 2006;98:71i-6i.
44. Plourde M, Cunnane SC. Extremely limited synthesis of long chain polyunsaturates in adults: implications for their dietary essentiality and use as supplements.Appl Physiol Nutr Metab 2007;32:619-34.
45. Fleith M, Clandinin MT. Dietary PUFA for preterm and term infants: review of clinical studies. Crit Rev Food Sci Nutr 2005;45:205-29.
46. Singh RB, Dubnov G, Niaz MA, et al. Effect of an Indo-Mediterranean diet on progression of coronary artery disease in high risk patients (Indo-Mediterranean Diet Heart Study): a randomized single-blind trial. Lancet 2002;360:1455-61.