Microarray analysis reveals that leptin induces autocrine/paracrine cascades to promote survival and proliferation of colon epithelial cells in an Apc genotype-dependent fashion

Molecular Carcinogenesis

Volumn 47, Issue 1, 2008, Pages 9-21

  Fenton, Jenifer I ^a   Lavigne, Jackie A ^b   Perkins, Susan N ^d   Liu, Huaitian ^b,c   Chandramouli, Gadisetti V R ^b   Shih, Joanna H ^b   Hord, Norman G ^a   Hursting, Stephen D ^d  

^a Michigan State University   (United States)

^b NATIONAL CANCER INSTITUTE   (United States)

^c SAIC FREDERICK INC   (United States)

^d UNIVERSITY OF TEXAS AT AUSTIN   (United States)

Author keywords

Colon cancer; IGF; IGFBP; IMCE; Leptin; Microarray; YAMC

Indexed keywords

BETA CATENIN; GROWTH FACTOR; LEPTIN; PROTEIN CRIM1; PROTEIN MDM2; PROTEIN NOV; PROTEIN PIK3R1; RETINOBLASTOMA PROTEIN; RETINOBLASTOMA PROTEIN 1; SOMATOMEDIN; SOMATOMEDIN BINDING PROTEIN 2; SOMATOMEDIN BINDING PROTEIN 3; SOMATOMEDIN BINDING PROTEIN 4; SOMATOMEDIN BINDING PROTEIN 5; SOMATOMEDIN BINDING PROTEIN 6; UNCLASSIFIED DRUG; WNT PROTEIN; MESSENGER RNA;

ARTICLE; AUTOCRINE EFFECT; CELL PROLIFERATION; CELL SURVIVAL; COLON CANCER; COLON CARCINOGENESIS; COLON MUCOSA; EPITHELIUM CELL; GENE MUTATION; GENOTYPE; HORMONE ACTION; HUMAN; MICROARRAY ANALYSIS; MULTIGENE FAMILY; OBESITY; PARACRINE SIGNALING; PRIORITY JOURNAL; SIGNAL TRANSDUCTION; TUMOR SUPPRESSOR GENE; UPREGULATION; ANIMAL; CELL DIVISION; COLON; CYTOLOGY; DNA MICROARRAY; DRUG EFFECT; GENE EXPRESSION REGULATION; GENETICS; INTESTINE MUCOSA; MOUSE; PHYSIOLOGY; POLYMERASE CHAIN REACTION; TRANSGENIC MOUSE;

ANIMALS; CELL DIVISION; CELL SURVIVAL; COLON; GENE EXPRESSION REGULATION; GENES, APC; GENOTYPE; HUMANS; INTESTINAL MUCOSA; LEPTIN; MICE; MICE, TRANSGENIC; OLIGONUCLEOTIDE ARRAY SEQUENCE ANALYSIS; POLYMERASE CHAIN REACTION; RNA, MESSENGER;

EID: 38349053772     PISSN: 08991987     EISSN: 10982744     Source Type: Journal    
DOI: 10.1002/mc.20357     Document Type: Article

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