Intracellular targeting of copper-transporting ATPase ATP7A in a normal and Atp7b-/- kidney

American Journal of Physiology - Renal Physiology

Volumn 294, Issue 1, 2008, Pages

  Linz, Rachel ^a   Barnes, Natalie L ^a   Zimnicka, Adriana M ^b   Kaplan, Jack H ^b   Eipper, Betty ^c   Lutsenko, Svetlana ^a,d  

^a OREGON HEALTH AND SCIENCE UNIVERSITY   (United States)

^b UNIVERSITY OF ILLINOIS AT CHICAGO   (United States)

^c UNIVERSITY OF CONNECTICUT HEALTH CENTER   (United States)

^d OREGON HEALTH AND SCIENCE UNIVERSITY   (United States)

Author keywords

ATP7B; Basolateral membrane; Trafficking; Wilson disease

Indexed keywords

ADENOSINE TRIPHOSPHATASE; COPPER; COPPER EXPORTING ADENOSINE TRIPHOSPHATASE; MENKES PROTEIN; WILSON DISEASE PROTEIN;

ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL TISSUE; ARTICLE; BASOLATERAL MEMBRANE; C57BL MOUSE; CELLULAR DISTRIBUTION; CONTROLLED STUDY; FEMALE; KIDNEY; KIDNEY DISTAL TUBULE; KIDNEY PROXIMAL TUBULE; LIVER; MALE; MOUSE; NONHUMAN; PRIORITY JOURNAL; PROTEIN EXPRESSION; WILSON DISEASE;

EID: 38349016602     PISSN: 1931857X     EISSN: 15221466     Source Type: Journal    
DOI: 10.1152/ajprenal.00314.2007     Document Type: Article

References (32)

1. Allen KJ, Buck NE, Cheah DM, Gazeas S, Bhathal P, Mercer JF. Chronological changes in tissue copper, zinc and iron in the toxic milk mouse and effects of copper loading. Biometals 19: 555-564, 2006.
2. Barnes N, Tsivkovskii R, Tsivkovskaia N, Lutsenko S. The copper-transporting ATPases, Menkes and Wilson disease proteins, have distinct roles in adult and developing cerebellum. J Biol Chem 280: 9640-9645, 2005.
3. Bearn AG. Wilson's disease. Am J Clin Nutr 9: 695-699, 1961.
4. Buiakova OI, Xu J, Lutsenko S, Zeitlin S, Das K, Das S, Ross BM, Mekios C, Scheinberg H, Gilliam CT. Null mutation of the murine ATP7B (Wilson disease) gene results in intracellular copper accumulation and late-onset hepatic nodular formation. Hum Mol Genet 8: 1665-1671, 1999.
5. Greenough M, Pase L, Voskoboinik I, Petris MJ, Wilson O'Brien A, Camakaris J. Signals regulating trafficking of Menkes (MNK; ATP7A) copper-translocating P-type ATPase in polarized MDCK cells. Am J Physiol Cell Physiol 287: C1463-C1471, 2004.
6. Grimes A, Hearn CJ, Lockhart P, Newgreen DF, Mercer JFB. Molecular basis of the brindled mouse mutant (Mobr): a murine model of Menkes disease. Hum Mol Genet 6: 1037-1042, 1997.
7. Hardman B, Michalczyk A, Greenough M, Camakaris J, Mercer JFB, Ackland ML. Hormonal regulation of the Menkes and Wilson copper-transporting ATPases in human placental Jeg-3 cells. Biochem J 402: 241-250, 2007.
8. -/- (Wilson disease gene) knockout mice. Am J Pathol 168: 423-434, 2006.
9. Ke BX, Llanos RM, Wright M, Deal Y, Mercer JFB. Alteration of copper physiology in mice overexpressing the human Menkes protein ATP7A. Am J Physiol Regul Integr Comp Physiol 290: R1460-R1467, 2006.
10. Kelleher SL, Lönnerdal B. Mammary gland copper transport is stimulated by prolactin through alterations in Ctr1 and Atp7A localization. Am J Physiol Regul Integr Comp Physiol 291: R1181-R1191, 2006.
11. Kodama H, Abe T, Takama M, Takahashi I, Kodama M, Nishimura M. Histochemical localization of copper in the intestine and kidney of macular mice: light and electron microscopic study. J Histochem Cytochem 41: 1529-1535, 1993.
12. Kurasaki M, Okabe M, Saito S, Suzuki-Kurasaki M. Copper metabolism in the kidney of rats administered copper and copper-metallothionein. Am J Physiol Renal Physiol 274: F783-F790, 1998.
13. La Fontaine S, Firth SD, Camakaris J, Englezou A, Theophilos MB, Petris MJ, Howie M, Lockhart PJ, Greenough M, Brooks H, Reddel RR, Mercer JFB. Correction of the copper transport defect of Menkes patient fibroblasts by expression of the Menkes and Wilson ATPases. J Biol Chem 273: 31375-31380, 1998.
14. La Fontaine S, Mercer JFB. Trafficking of the copper-ATPases, ATP7A and ATP7B: role in copper homeostasis. Arch Biochem Biophys 463: 149-167, 2007.
15. Linder MC, Hazegh-Azam M. Copper biochemistry and molecular biology. Am J Clin Nutr 63: 797S-811S, 1996.
16. Monty JF, Llanos RM, Mercer JFB, Kramer DR. Copper exposure induces trafficking of Menkes protein in intestinal epithelium of ATP7A transgenic mice. J Nutr 135: 2762-2766, 2005.
17. Moore SDP, Cox DW. Expression in mouse kidney of membrane copper transporters Atp7a and Atp7b. Nephron 92: 629-634, 2002.
18. Motonishi S, Hayashi H, Fujita Y, Okada H, Kusakabe A, Ito M, Miyamoto K, Ueno T. Copper- and iron-rich matrices in hepatocellular lipofuscin particles of a young male patient: diagnostic ultrastructures for Wilson disease. Ultrastruct Pathol 30: 409-414, 2006.
19. Murata Y, Kodama H, Abe T, Ishida N, Nishimura M, Levinson B, Gitschier J, Packman S. Mutation analysis and expression of the mottled gene in the macular mouse model of Menkes disease. Pediatr Res 42: 436-442, 1997.
20. Niciu MJ, Ma XM, El Meskini R, Ronnett GV, Mains RE, Eipper BA. Developmental changes in the expression of ATP7A during a critical period in postnatal neurodevelopment. Neuroscience 139: 947-964, 2006.
21. Nomiyama K, Nomiyama H, Kameda N, Tsuji A, Sakurai H. Mechanism of hepatorenal syndrome in rats of Long-Evans Cinnamon strain, an animal model of fulminant Wilson's disease. Toxicology 132: 201-214, 1999.
22. Nooijen JL, De Groot CJ, Van den Hamer CJ, Monnens LA, Willemse J, Niermeijer MF. Trace element studies in three patients and a fetus with Menkes' disease. Effect of copper therapy. Pediatr Res 15: 284-289, 1981.
23. Nose Y, Kim BE, Thiele DJ. Ctr1 drives intestinal copper absorption and is essential for growth, iron metabolism, and neonatal cardiac function. Cell Metab 4: 235-244, 2006.
24. Nyasae L, Bustos R, Braiterman L, Eipper B, Hubbard A. Dynamics of endogenous ATP7A (Menkes protein) in intestinal epithelial cells: copper-dependent redistribution between two intracellular sites. Am J Physiol Gastrointest Liver Physiol 292: G1181-G1194, 2007.
25. Okabe M, Nakayama K, Kurasaki M, Yamasaki F, Aoyagi K, Yamanoshita O, Sato S, Okui T, Ohyama T, Kasai N. Direct visualization of copper-metallothionein in LEC rat kidneys: application of autofluorescence signal of copper-thiolate cluster. J Histochem Cytochem 44: 865-873, 1996.
26. Parker MM, Humoller FL, Mahler DJ. Determination of Copper and Zinc in Biological Material. Clin Chem 13: 40-48, 1967.
27. Pase L, Voskoboinik I, Greenough M, Camakaris J. Copper stimulates trafficking of a distinct pool of the Menkes copper ATPase (ATP7A) to the plasma membrane and diverts it into a rapid recycling pool. Biochem J 378: 1031-1037, 2004.
28. Prohaska JR. Changes in tissue growth, concentrations of copper, iron, cytochrome oxidase and superoxide dismutase subsequent to dietary or genetic copper deficiency in mice. J Nutr 113: 2148-2158, 1983.
29. Steveson TC, Ciccotosto GD, Ma XM, Mueller GP, Mains RE, Eipper BA. Menkes protein contributes to the function of peptidylglycine alpha-amidating monooxygenase. Endocrinology 144: 188-200, 2003.
30. Suzuki-Kurasaki M, Okabe M, Kurasaki M. Copper-metallothionein in the kidney of macular mice: a model for Menkes disease. J Histochem Cytochem 45: 1493-1501, 1997.
31. Tanzi RE, Petrukhin K, Chernov I, Pellequer JL, Wasco W, Ross B, Romano DM, Parano E, Pavone L, Brzustowicz LM, Devoto M, Peppercorn J, Bush AI, Sternlieb I, Pirastu M, Gusella JF, Evgrafov O, Penchaszadah GK, Honig B, Edelman IS, Soares MB, Scheinberg IH, Gilliam TC. The Wilson disease gene is a copper transporting ATPase with homology to the Menkes disease gene. Nat Genet 5: 344-350, 1993.
32. Yoshimura N. Histochemical localization of copper in various organs of brindled mice. Pathol Int 44: 14-19, 1994.