Mechanism of hepatorenal syndrome in rats of Long-Evans Cinnamon strain, an animal model of fulminant Wilson's disease

Toxicology

Volumn 132, Issue 2-3, 1999, Pages 201-214

  Nomiyama, Kazuo ^a   Nomiyama, Hiroko ^a   Kameda, Naoki ^a   Tsuji, Akihiro ^b   Sakurai, Hiromu ^b  

^a JICHI MEDICAL UNIVERSITY   (Japan)

^b KYOTO PHARMACEUTICAL UNIVERSITY   (Japan)

Author keywords

Copper; Kidney; LEC rat; Liver; Metallothionein; Wilson's disease

Indexed keywords

AMINO ACID; COPPER; METALLOTHIONEIN;

ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; HEPATORENAL SYNDROME; JAUNDICE; KIDNEY; KIDNEY DISEASE; LIVER; LIVER DYSFUNCTION; MALE; NONHUMAN; PRIORITY JOURNAL; RAT; WILSON DISEASE;

ANIMALS; COPPER; DISEASE MODELS, ANIMAL; HEPATOLENTICULAR DEGENERATION; HEPATORENAL SYNDROME; JAUNDICE; KIDNEY; LIVER; MALE; METALLOTHIONEIN; RATS; RATS, LONG-EVANS;

EID: 0033066122     PISSN: 0300483X     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0300-483X(99)00005-0     Document Type: Article

References (32)

1. Bonsnes R.W., Taussky H.H. On the colorimetric determination of creatinine by Jaffe reaction. J. Biol. Chem. 158:1945;581-591.
2. 15N]nitrate in biological fluids. Anal. Biochem. 126:1982;131-138.
3. Guan R., Yeo P.P., Ng H.S. et al. Wilson's disease revisited in the tropics. Ann. Acad. Med. Singap. 15:1986;186-193.
4. Habu H., Yokoi I., Kabuto H., Mori A. Application of automated flow injection analysis to determine nitrite and nitrate in mouse brain. Neuroreport. 5:1994;1571-1573.
5. Jin N., Kimura E., Itokawa Y. A determination method for metallothionein in rat liver by high-performance liquid chromatography. Jpn. J. Hygiene. 48:1993;573-577.
6. Kanno S., Aoki Y., Suzuki J.S., Takeichi N., Misawa S., Suzuki K.T. Enhanced synthesis of metallothionein as a possible cause of abnormal copper accumulation in LEC rats. J. Inorg. Biochem. 56:1994;117-125.
7. Kawamoto K., Hirashima T., Mori S. et al. Pathological and laboratory findings of 'LEC/Otk' rats maintained under SPF conditions. Mori M., Yoshida M.C., Takeichi N., Taniguchi N. The LEC Rat. 1991;30-40 Springer, Tokyo.
8. Mayabara H. Alkaline phosphatase. Takeuchi T., Ogawa K. New Enzyme Histochemistry. 1980;284-286 Asakura, Tokyo.
9. Nair J., Sone H., Nagao M., Barbin A., Bartsch H. Copper-dependent formation of miscoding etheno-DNA adducts in the liver of Long Evans Cinnamon (LEC) rats developing hereditary hepatitis and hepatocellular carcinoma. Cancer Res. 56:1996;1267-1271.
10. Nomiyama K. Early detection of chronic cadmium poisoning. Jpn. J. Med. 2587:1973;132.
11. Nomiyama K., Nomiyama H. Cadmium-induced renal dysfunction. J. Trace Elem. Exp. Med. 11:1998;275-288.
12. Nomiyama K., Nomiyama H., Nomura Y. et al. Effects of dietary cadmium on rhesus monkeys. Environ. Health Perspect. 28:1979;223-243.
13. Ohhira M., Ono M., Ohhira M. et al. Changes in free radical-metabolizing enzymes and lipid peroxide in the liver of Long-Evans with Cinnamon-like coat color rats. J. Gastroentrol. 30:1995;619-623.
14. Okabe M., Nakayama K., Kurasaki M. et al. Direct visualization of copper-metallothionein in LEC rat kidneys: application of autofluorescence signal of copper-thiolate cluster. J. Histochem. Cytochem. 44:1996;865-873.
15. Ravin H.A. An improved colorimetric enzymatic assay of ceruloplasmin. J. Lab. Clin. Med. 58:1961;161-168.
16. Sakurai H., Fukudome A., Tawa R. et al. Unusual accumulation of copper related to induction of metallothionein in the liver of LEC rats. Biochem. Biophys. Res. Commun. 184:1992;1393-1397.
17. Sakurai H., Kamada H., Fukudome A. et al. Copper-induction in the liver of LEC rats. Biochem. Biophys. Res. Commun. 185:1992;548-552.
18. Sakurai H., Satoh H., Hatanaka A. et al. Unusual generation of hydroxyl radicals in hepatic copper-metallothionein of LEC (Long-Evans Cinnamon) rats in the presence of hydrogen peroxide. Biochem. Biophys. Res. Commun. 199:1994;313-318.
19. Sugawara N., Sugawara C., Katakura M., Takahashi H., Mori M. Copper metabolism in the LEC rat: involvement of induction of metallothionein and disposition of zinc and iron. Experientia. 47:1991;1060-1063.
20. Sugawara N., Sato M., Yuasa M., Sugawara C. Biliary excretion of copper, metallothionein, and glutathione into Long-Evans Cinnamon rats: a convincing animal model for Wilson disease. Biochem. Mol. Med. 55:1995;38-42.
21. Suzuki K.T. Disordered copper metabolism in LEC rats, an animal model of Wilson disease: roles of metallothionein. Res. Commun. Mol. Pathol. Pharmacol. 89:1995;221-240.
22. Suzuki K.T., Kanno S., Misawa S., Aoki Y. Copper metabolism leading to and following acute hepatitis in LEC rats. Toxicology. 97:1995;81-92.
23. Takeuchi T. Aminotransferase. Takeuchi T., Ogawa K. New Enzyme Histochemistry. 1980;207-215 Asakura, Tokyo, Tokyo.
24. Takeuchi T. Glutamyl (-transpeptidase. Takeuchi T., Ogawa K. New Enzyme Histochemistry. 1980;175-178 Asakura, Tokyo.
25. Tochimaru H., Akutsu Y., Nagata Y., Takekoshi Y., Matsumoto S., Takeichi N. Acute tubular necrosis in LEC rats with hereditary hepatic failure: a new animal model of hepatorenal syndrome. Mori M., Yoshida M.C., Takeichi N., Taniguchi N. The LEC Rat. 1991;103-113 Springer, Tokyo.
26. World Health Organisation, 1991. Principles and Methods for the Assessment of Nephrotoxicity Associated with Exposure to Chemicals, World Health Organisation, Geneva, pp. 178-179.
27. Wu J., Forbes J.R., Cox D.W. Further characterization of the Atp7b gene deletion in LEC rats. J. Trace Elem. Exp. Med. 10:1997;147-152.
28. Yagi K. A simple fluorometric assay for lipoperoxide in blood plasma. Biochem. Med. 15:1976;212-216.
29. Yamada T., Sogawa K., Suzuki T., Isumi K., Agui T., Matsumoto K. Elevation of the level of lipid peroxidation associated with hepatic injury in LEC mutant rat. Res. Commun. Chem. Pathol. Pharmacol. 77:1992;121-124.
30. Yamada T., Suzuki Y., Agui T., Matsumoto K. Elevation of metallothionein gene expression associated with hepatic copper accumulation in Long-Evans Cinnamon mutant rat. Biochim. Biophys. Acta. 1131:1992;188-191.
31. Yamamoto Y., Sone H., Yamashita S. et al. Oxidative stress in LEC rats evaluated by plasma antioxidants and free fatty acids. J. Trace Elem. Exp. Med. 10:1997;129-134.
32. Yarze J.C., Martin P., Munoz S.J., Friedman L.S. Wilson's disease: current status. Am. J. Med. 92:1992;643-654.