Paradox of glucocorticoid-induced cytosolic phospholipase A2 group IVA messenger RNA expression involves glucocorticoid receptor binding to the promoter in human amnion fibroblasts

Biology of Reproduction

Volumn 78, Issue 1, 2008, Pages 193-197

  Guo, Chunming ^a   Yang, Zhen ^a   Li, Wenjiao ^b   Zhu, Ping ^c   Myatt, Leslie ^d   Sun, Kang ^a,d  

^a FUDAN UNIVERSITY   (China)

^b Shanghai Changning Maternity and Infant Health Hospital   (China)

^c 401 Hospital of PLA   (China)

^d UNIVERSITY OF CINCINNATI COLLEGE OF MEDICINE   (United States)

Author keywords

Amnion; Cortisol; Glucocorticoid receptor; Parturition; PLA2G4A; Placenta; Pregnancy; Prostaglandin

Indexed keywords

5,6 DICHLOROBENZIMIDAZOLE RIBOSIDE; CYTOKINE; GLUCOCORTICOID; GLUCOCORTICOID RECEPTOR; HYDROCORTISONE; INTERLEUKIN 1BETA; INTERLEUKIN 6; MESSENGER RNA; MIFEPRISTONE; NUCLEAR PROTEIN; PHOSPHOLIPASE A2; PHOSPHOLIPASE A2 GROUP IVA; RECEPTOR ANTIBODY; TUMOR NECROSIS FACTOR ALPHA; UNCLASSIFIED DRUG;

AMNION CELL; ARTICLE; CHROMATIN IMMUNOPRECIPITATION; DOSE RESPONSE; ELECTROPHORESIS; GENE EXPRESSION; HUMAN; HUMAN CELL; NUCLEOTIDE SEQUENCE; PRIORITY JOURNAL; PROMOTER REGION; RECEPTOR BINDING; STIMULATION;

AMNION; BASE SEQUENCE; CELLS, CULTURED; CYTOKINES; CYTOSOL; FIBROBLASTS; GROUP IV PHOSPHOLIPASES A2; HUMANS; HYDROCORTISONE; PROMOTER REGIONS (GENETICS); PROTEIN BINDING; RECEPTORS, GLUCOCORTICOID; RESPONSE ELEMENTS; RNA, MESSENGER; TRANSCRIPTION, GENETIC; UP-REGULATION;

EID: 38149057531     PISSN: 00063363     EISSN: None     Source Type: Journal    
DOI: 10.1095/biolreprod.107.063990     Document Type: Article

References (31)

1. Rhen T, Cidlowski JA. Antiinflammatory action of glucocorticoids - new mechanisms for old drugs. N Engl J Med 2005; 353:17117-17123.
2. Adcock IM, Caramori G. Cross-talk between pro-inflammatory transcription factors and glucocorticoids. Immunol Cell Biol 2001; 79:376-384.
3. Swantek JL, Cobb MH, Geppert TD. Jun N-terminal kinase/stress-activated protein kinase (JNK/SAPK) is required for lipopolysaccharide stimulation of tumor necrosis factor alpha (TNF-alpha) translation: glucocorticoids inhibit TNF-alpha translation by blocking JNK/SAPK. Mol Cell Biol 1997; 17:6274-6282.
4. Amano Y, Lee SW, Allison AC. Inhibition by glucocorticoids of the formation of interleukin-1 alpha, interleukin-1 beta, and interleukin-6: mediation by decreased mRNA stability. Mol Pharmacol 1993; 43:176-182.
5. Tobler A, Meier R, Seitz M, Dewald B, Baggiolini M, Fey MF. Glucocorticoids downregulate gene expression of GM-CSF, NAP-1/IL-8, and IL-6, but not of M-CSF in human fibroblasts. Blood 1992; 79:45-51.
6. Newton R, Seybold J, Kuitert LM, Bergmann M, Barnes PJ. Repression of cyclooxygenase-2 and prostaglandin E2 release by dexamethasone occurs by transcriptional and post-transcriptional mechanisms involving loss of polyadenylated mRNA. J Biol Chem 1998; 273:32312-32321.
7. Challis JR, Sloboda DM, Alfaidy N, Lye SJ, Gibb W, Patel FA, Whittle WL, Newnham JP. Prostaglandins and mechanisms of preterm birth. Reproduction 2002; 124:1-17.
8. Irvine RF. How is the level of free arachidonic acid controlled in mammalian cells? Biochem J 1982; 204:3-16.
9. Kniss DA. Cyclooxygenases in reproductive medicine and biology. J Soc Gynecol Investig 1999; 6:285-292.
10. Newton R, Kuitert LM, Slater DM, Adcock IM, Barnes PJ. Cytokine induction of cytosolic phospholipase A2 and cyclooxygenase-2 mRNA is suppressed by glucocorticoids in human epithelial cells. Life Sci 1997; 60: 67-78.
11. Newton R. Molecular mechanisms of glucocorticoid action: what is important? Thorax 2000; 55:603-613.
12. Didonato JA, Saatcioglu F, Karin M. Molecular mechanisms of immunosuppression and antiinflammatory activities by glucocorticoids. Am J Respir Crit Care Med 1996; 154(Pt 2):S11-S15.
13. Auphan N, DiDonato JA, Rosette C, Helmberg A, Karin M. Immunosuppression by glucocorticoids: inhibition of NF-kappa B activity through induction of I kappa B synthesis. Science 1995; 270:286-290.
14. Duchesne MJ, Thaler-Dao H, de Paulet AC. Prostaglandin synthesis in human placenta and fetal membranes. Prostaglandins 1978; 15:19-42.
15. Challis JRG, Matthews SG, Gibb W, Lye SJ. Endocrine and paracrine regulation of birth at term and preterm. Endocr Rev 2000; 21:514-550.
16. Casey ML, MacDonald PC, Mitchell MD. Despite a massive increase in cortisol secretion in women during parturition, there is an equally massive increase in prostaglandin synthesis. A paradox? J Clin Invest 1985; 75: 1852-1857.
17. Economopoulos P, Sun M, Purgina B, Gibb W. Glucocorticoids stimulate prostaglandin H synthase type-2 (PGHS-2) in the fibroblast cells in human amnion cultures. Mol Cell Endocrinol 1996; 117:141-147.
18. Blumenstein M, Hansen WR, Deval D, Mitchell MD. Differential regulation in human amnion epithelial and fibroblast cells of prostaglandin E(2) production and prostaglandin H synthase-2 mRNA expression by dexamethasone but not tumour necrosis factor-alpha. Placenta 2000; 21: 210-217.
19. Potestio FA, Zakar T, Olson DM. Glucocorticoids stimulate prostaglandin synthesis in human amnion cells by a receptor-mediated mechanism. J Clin Endocrinol Metab 1988; 67:1205-1210.
20. 2 and prostaglandin H synthase type 2 but not microsomal prostaglandin E synthase (PGES) and cytosolic PGES expression in cultured primary human amnion cells. J Clin Endocrinol Metab 2003; 88:5564-5571.
21. 2 gene. Nucleic Acids Res 1994; 22:5093-5098.
22. 2 isozymes in pregnancy and parturition. Prostaglandins Leukot Essent Fatty Acids 2004; 70:87-100.
23. 2 activity and gene expression are stimulated by tumor necrosis factor: dexamethasone blocks the induced synthesis. Proc Natl Acad Sci U S A 1993; 90:4475-4479.
24. 2 gene. Am J Physiol Lung Cell Mol Physiol 2000; 278:L649-L657.
25. 2 activity and protein synthesis is blocked by dexamethasone in rat mesangial cells. FEBS Lett 1993; 333:339-343.
26. 2 activity. J Biol Chem 1999; 274:17202-17208.
27. 2 activity: evidence for glucocorticoid receptor-mediated regulation. Mol Cell Endocrinol 1998; 137:117-125.
28. 2 and prostaglandin H synthase-2 by interleukin-1 beta in WISH cells in inhibited by dexamethasone. Prostaglandins 1996; 51:107-124.
29. Whittle WL, Patel FA, Alfaidy N, Holloway AC, Fraser M, Gyomorey S, Lye SJ, Gibb W, Challis JR. Glucocorticoid regulation of human and ovine parturition: the relationship between fetal hypothalamic-pituitary-adrenal axis activation and intrauterine prostaglandin production. Biol Reprod 2001; 64:1019-1032.
30. Gibb W, Lavoie JC. Effects of glucocorticoids on prostaglandin formation by human amnion. Can J Physiol Pharmacol 1990; 68:671-676.
31. 2 expression by interleukin-1beta in cultured primary human amnion fibroblasts. Placenta 2006; 27:164-170.