Glucocorticoid regulation of human and ovine parturition: The relationship between fetal hypothalamic-pituitary-adrenal axis activation and intrauterine prostaglandin production

Biology of Reproduction

Volumn 64, Issue 4, 2001, Pages 1019-1032

  Whittle, W L ^a   Patel, F A ^a   Alfaidy, N ^a   Holloway, A C ^a   Fraser, M ^a   Gyomorey, S ^a   Lye, S J ^a   Gibb, W ^a   Challis, J R G ^a  

^a UNIVERSITY OF TORONTO   (Canada)

Author keywords

ACTH; Adrenal cortex; Anterior pituitary; Cortisol; CRH; Cytokines; Decidua; Estradiol; Estradiol receptor; Glucocorticoid receptor; Hormone action; Hypothalamus; NPY; Oxytocin; Parturition; Pregnancy; Progesterone; Syncytiotrophoblast; Trophoblast

Indexed keywords

CORTICOTROPIN RELEASING FACTOR; ESTRADIOL; GLUCOCORTICOID; HYDROCORTISONE;

ADRENAL CORTEX; BIRTH; CATTLE; FETUS; FETUS MEMBRANE; HORMONAL REGULATION; HORMONE METABOLISM; HORMONE RELEASE; HYPOTHALAMUS HYPOPHYSIS ADRENAL SYSTEM; NONHUMAN; PLACENTA; PRIORITY JOURNAL; PROSTAGLANDIN SYNTHESIS; SHORT SURVEY; TROPHOBLAST;

ANIMALIA; BOS TAURUS; OVIS;

EID: 0035084148     PISSN: 00063363     EISSN: None     Source Type: Journal    
DOI: 10.1095/biolreprod64.4.1019     Document Type: Short Survey

References (158)

1. Preventing preterm birth
2. Controversies in tocolytic therapy
3. Maternal but not fetal corticosteroids restricts fetal growth
4. Preterm birth prevention: Effectiveness of current strategies
5. Glucocorticoids and the preparation for life after birth: Are there long-term consequences of the life insurance?
6. Prostaglandins and parturition
7. The initiation and inhibition of labor. Toward a molecular understanding
8. Hypothalamic paraventricular nuclear lesions delay corticotroph maturation in the fetal sheep anterior pituitary
9. Bilateral destruction of the fetal paraventricular nuclei prolong gestation in sheep
10. The effect of hypothalamic lesions on the length of gestation in fetal sheep
11. Expression of prostaglandin G/H synthase 1 and 2 in ovine amnion and placenta following glucocorticoid-induced labor onset
12. The trigger for parturition in sheep: Fetal hypothalamus of placenta?
13. Initiation of spontaneous labor
14. Cellular localization of corticotropin releasing factor mRNA in the ovine brain
15. CRH and AVP-induced changes in synthesis and release of ACTH from ovine fetal pituitary in vitro: Negative influences of cortisol
16. Characteristics and developmental changes of corticotropin-releasing hormone binding sites in the foetal sheep anterior pituitary
17. Changes in pituitary responses to synthetic ovine corticotropin releasing factor in fetal sheep
18. Regulation of CRH and AVP mRNA in the developing ovine hypothalamus: Effects of stress and glucocorticoids
19. In vitro stimulation and inhibition of adrenocorticotropin release by pituitary cells from ovine fetuses and lambs
20. Development of adrenocorticotropin (1-39) and precursor peptide secretory responses in the fetal sheep during the last third of gestation
21. Developmental changes in the distribution of proopiomelanocortin and prolactin mRNA in the pituitary of the ovine fetus and lamb
22. Effects of labor on pituitary expression of proopiomelanocortin, prohormone convertase (PC)-1 PC-2 and glucocorticoid receptor mRNA in fetal sheep
23. Development of the pituitary-adrenal axis in chronically cannulated ovine fetuses
24. Time trend analysis of plasma cortisol concentrations in the fetal sheep in relation to parturition
25. The role of cytochrome P45017α hydroxylase and 3βhydroxysteroid dehydrogenase in the integration of gonadal and adrenal steroidogenesis vía Δ5 and Δ4 pathways of steroidogenesis in mammals
26. Modifications of the steroidogenic pathway during spontaneous and adrenocorticotropin-induced maturation of the ovine fetal adrenal
27. Chronic administration of low doses of adrenocorticotropin to hypophysectomized fetal sheep leads to normal term labor
28. Activation of the ovine fetal adrenal function by pulsatile or continuous administration of ACTH 1-24 I. Effects on plasma corticosteroids
29. Developmental regulation of cor ticotrophin receptor (ACTH-R) gene expression in the adrenal gland of the ovine fetus and newborn lamb: Effects of hypoxia during late pregnancy
30. ACTH induction of the maturation of ACTH sensitive adenylate cyclase system in the ovine fetal adrenal
31. Leptin suppresses the late gestation increase in ACTH and cortisol in fetal sheep: Metabolic cues and the timing of parturition
32. Regulation of the hypothalamo-pituitaryadrenocortical axis in fetal sheep
33. Maturation and activation of the hypothalamic-pituitary adrenal function in fetal sheep
34. Corticosteroid-binding globulin (CBG) in fetal development
35. Glucocorticoid induced increase in plasma corticosteroid binding globulin levels in fetal sheep is associated with increased biosynthesis and alterations in glycosylation
36. Ontogeny and regulation of corticosteroid binding globulin capacity in plasma of fetal and newborn lambs
37. Possible role of cortisol in the stimulation of cortisol binding capacity in the plasma of fetal sheep
38. Developmental and glucocorticoid regulation if pituitary 11-hydroxysteroid dehydrogenase 1 gene expression in the ovine fetus and lamb
39. Characterization of an ovine glucocorticoid receptor cDNA and developmental changes in its mRNA levels in the fetal sheep hypothalamus, pituitary and adrenal gland
40. The effect of estradiol on output of adrenocorticotropin and prolactin by fetal sheep anterior pituitary cells
41. Influence of estradiol and androstendione on ACTH and cortisol secretion in the ovine fetus
42. Ontogeny of estrogen sufatase activity in ovine fetal hypothalamus, hippocampus and brainstem
43. Prostaglandins in the circulation of the fetal lamb
44. The nutritional regulation of plasma prostaglandin E concentrations in the fetus and pregnant ewe during late gestation
45. Rapid increase of fetal corticosteroids after prostaglandin E2
46. Control of parturition
47. Altered fetal pituitary-adrenal function in the ovine fetus treated with RU486 and meloxicam (MEL), an inhibitor of prostaglandin synthase-II
48. Prostaglandin regulation of fetal plasma adrenocorticotropin and cortisol concentrations in late-gestation sheep
49. Continuous intrafetal infusion of prostaglandin E2 prematurely activates the hypothalamus-pituitary-adrenal axis and induces parturition in sheep
50. 2 is a positive regulator of adrenocorticotropin receptors, 3 beta-hydroxysteroid dehydrogenase, and 17 alpha-hydroxylase expression in bovine adrenocortical cells
51. Ovine placental steroid 17alpha-hydroxylase/C-17,20 lyase, aromatase and sulfatase in dexamethasone-induced and natural parturition
52. Mechanism of action of glucocorticoids in induction of ovine parturition: Effect on placental steroid metabolism
53. The fetal to maternal progression of PGHS-2 expression in ovine intrauterine tissues during the course of labor
54. Temporal expression of prostaglandin synthase type 2 (PGHS-2) and P450(C17) in ovine placentomes with the natural onset of labor
55. Inhibition of prostaglandin production by nimesulide is accompanied by changes in expression of the cassette of uterine labor-related genes in pregnant sheep
56. Prostaglandin production at the onset of ovine parturition is regulated by both estradiol-dependent and estradiol-independent pathways
57. Localization and temporal expression of glucocortcoid receptor (GR) protein in ovine intrauterine tissues with the natural onset of labor
58. Effect of labor on the expression of oxytocin receptor, cytochrome P450 aromatase and estradiol receptor in the reproductive tract of the late pregnant ewe
59. Effect of ovarian steroids and oxytocin on the production of prostaglandin E2, prostaglandin F2alpha and endothelin-1 from cow oviductal epithelial cell monolayers in vitro
60. Molecular mechanisms of diverse actions of prostanoid receptors
61. cAMP-dependent transactivation involving the homeodomain protein Pbx1
62. Prostaglandin E2, fetal maturation and ovine parturition
63. Hormonal control of GAP junction formation in sheep myometrium during parturition
64. The molecular basis of labour and tocolysis
65. Expression and regulation of the messenger ribonucleic acid encoding the prostaglandin F (2alpha) receptor in the rat myometrium during pregnancy and labor
66. Increased expression of the rat myometrial oxytocin receptor messenger ribonucleic acid during labor requires both mechanical and hormonal signals
67. Regulation of transcripts encoding the myometrial gap junction protein, connexin 43, by estrogen and progesterone
68. Maternal plasma and amniotic fluid cortisol and progesterone concentrations between women with and without term labor
69. Cortisol in amniotic fluid during human gestation
70. Human amniotic membrane corticosteroid 11-oxidoreductase activity
71. Uterine actvity after betamethasone administration for the enhancement of fetal lung maturation
72. The effect of corticosteroid administration on uterine activity and preterm labor in high order multiple gestations
73. The efficacy of intraamniotic steroids for induction of labor
74. Theoretical basis for endocrine control of gestation: A comparative approach
75. Endocrine and pharmacological factors which influence the onset of labour in rhesus monkeys
76. Plasma estrone, estradiol, progesterone and 17-hydroxy-progesterone in human pregnancy
77. Production of premature delivery in rhesus monkeys by androstendione infusion
78. Pulsatile infusion of ACTH into the fetal circulation of rhesus monkeys leads to premature labor and delivery
79. Pathogenesis of preterm labor and premature rupture of membranes associated with intraamniotic infection
80. The accumulation of prostaglandins (PG) in amniotic fluid is an aftereffect of labor and not indicative of a role for PGE2 or PGF2 alpha in the initiation of human parturition
81. The extracellular matrix of the human fetal membranes: Structure and function
82. The expression of cyclooxygenase-2 (COX-II) in amnion and decidua following spontaneous labour
83. Localization of prostaglandin H synthase type 2 protein and mRNA in term human fetal membranes and decidua
84. Prostaglandin endoperoxide H synthase-2 and 2 messenger ribonucleic acid levels in human amnion with spontaneous labour onset
85. Prostaglandin endoperoxide synthase (PGHS) activity and immunoreactive PGHS-1 and PGHS-2 levels in human amnion throughout gestation and at term
86. The characterization of human amnion epithelial and mesenchymal cells: Cellular expression, activity and glucocorticoid regulation of prostaglandin output
87. Glucocorticoids stimulate prostaglandin H synthase type-2 (PGHS-2) in the fibroblast cells in human amnion cell cultures
88. Glucocorticoids stimulate the expression of prostaglandin endoperoxide H synthase-2 in amnion cells
89. Stimulation of cultured amnion prostaglandin endoperoxide H synthase activity by glucocorticoids and phorbol ester
90. Glucocorticoids stimulate prostaglandin synthesis in human amnion cells by a receptor mediated mechanism
91. Differential regulation in human amnion epithelial and fibroblast cells of prostaglandin E(2) production and prostaglandin H synthase-2 mRNA expression by dexamethasone but not tumor necrosis factor-alpha
92. Immunohistochemical localization of the glucocorticoid receptor in human fetal membranes and decidua at term and preterm delivery
93. Dexamethasone differentially regulates prostaglandin E2 (PGE2) production in amnion fibroblast and epithelial cells
94. Cyclic AMP response element mediates dexamethasone induced suppression of prostaglandin H synthase-2 gene expression in human amnion WISH cells
95. Interleukin-1b and dexamethasone regulate gene expression of prostaglandin H synthase-2 via the NFkB pathway in human amnion WISH cells
96. Rapid and transient induction of cyclooxygen ase 2 by epidermal growth factor in human amnion-derived WISH Cells
97. Studies on the action of dexamethasone on prostaglandin output by freshly dispersed amnion cells
98. Relation between cyclic AMP and prostaglandin output by dispersed cells from human amnion and decidua
99. Epidermal growth factor-stimulated prostaglandin E2 production in human amnion cells: Specificity and nonesterified arachidonic acid dependency
100. Regulation of prostaglandin E2 synthesis in human anmion by protein kinase C
101. Mechanism of interleukin-1 beta stimulation of human amnion prostaglandin biosynthesis: Mediation via a novel inducible cyclooxygenase
102. Interleukin-1 beta regulates the inducible cyclooxygenase in amnion-derived WISH cells
103. Tumor necrosis factor-alpha stimulates increased expression of prostaglandin endoperoxide H synthase type 2 mRNA in amnion-derived WISH cells
104. Biosynthesis of interleukin-6 by cultured chorion leave cells: Regulation by cytokines
105. Decidual cell biosynthesis of interleukin-6: Regulation by inflammatory cytokines
106. Inflammatory mediators regulate interleukin-8 production by cultured gestational tissues: Evidence for a cytokine network at the chorio-decidual interface
107. Peptide signaling in human placenta and membranes: Autocrine, paracrine and endocrine mechanisms
108. Key enzymes of prostaglandin biosynthesis and metabolism. Coordinate regulation of expression by cytokines in gestational tissues: A review
109. Does interleukin 10 (IL-10) block interleukin-1B (IL-1b) induced preterm labour in rhesus monkeys?
110. +-dependent prostaglandin dehydrogenase, carbonyl reductase, and cytochrome P450-dependent prostaglandin omega-hydroxylase
111. Localization of 15-hydroxyprostaglandin dehydrogenase in human fetal membranes, decidua, placenta
112. +-dependent 15-hydroxyprostaglandin dehydrogenase in cultured chorion trophoblast and villous trophoblast cells and in chorion explants, before and with spontaneous labor
113. 15-Hydroxyprostaglandin dehydrogenase (PGDH): Implications in preterm labor with and without ascending infection
114. Immunohistochemical localization, mRNA abundance and activity of 15-hydroxyprostaglandin dehydrogenase in placenta and fetal membranes during term and preterm labor
115. Steroid regulation of prostaglandin dehydrogenase activity and expression in human term placenta and chorio-decidua in relation to labor
116. Endocrine and paracrine regulation of birth at term and preterm
117. Cortisol as a mineralocorticoid in human disease
118. Actions of placental and fetal adrenal steroid hormones in primate pregnancy
119. Developmental increase in expression of the messenger ribonucleic acid and protein levels of 11Bhydroxysteroid dehydrogenase types 1 and 2 in the baboon placenta
120. Regulation of 11beta-hydroxysteroid dehydrogenase type-2 by progesterone, estrogen and the cyclic adenosine 5′-monophosphate pathway in cultured human placental and chorionic trophoblasts
121. Prostaglandin effects on 11βhydroxysteroid dehydrogenase type 1 and 2 in human chorion and placental trophoblast cells
122. Differential expression of 11 beta-hydroxysteroid dehydrogenase types 1 and 2 in human placenta and fetal membranes
123. Local modulation by 11betahydroxysteroid dehydrogenase of glucocorticoid effects on the activity of 15-prostaglandin dehydrogenase in human chorion and placental trophoblast cells
124. Local regulation of prostaglandin production by 11β hydroxysteroid dehydrogenase type I in the human fetal membranes at term
125. Corticotrophin-releasing hormone production by the placenta and fetal membranes
126. Corticotropin-releasing hormone in human pregnancy and parturition
127. Characterization and gestational regulation of corticotropin releasing hormone messenger RNA in human placenta
128. Steroids modulate corticotropinreleasing hormone production in human fetal membranes and placenta
129. Effect of betamethasone in vivo on placental corticotropin-releasing hormone in human pregnancy
130. Maternal CRH as a predictor of impending preterm birth
131. Corticotropin-releasing hormone receptor subtype-1 (CRH-R1) is significantly upregulated at the time of labor in the human myometrium
132. Activation of protein kinase C by oxytocin inhibits the biological activity of the human myometrial corticotropin releasing hormone receptor at term
133. The biological activity of the corticotropin-releasing hormone receptoradenylate cyclase complex in human myometrium is reduced at the end of pregnancy
134. High levels of corticotropin-releasing hormone immunoreactivity in maternal and fetal plasma during pregnancy
135. Immunoreactive corticotropinreleasing hormone, adrenocorticotropin and cortisol in human plasma during pregnancy and delivery and postpartum
136. Plasma corticotropin-releasing factor (CRF) in normal pregnancy
137. Elevated levels of umbilical cord plasma corticotro pin-releasing hormone in growth-retarded fetuses
138. Maternal plasma corticotropin-releasing hormone associated with stress at 20 weeks gestation in pregnancies ending in preterm delivery
139. Characteristics of parturition
140. Corticotropin-releasing hormone induced vasodilation in the human fetal placental circulation
141. Corticotropin releasing hormine directly and preferentially stimulates dehydroepiandrostendione sulfate secretion by human fetal adrenal cortical cells
142. Molecular mechanisms involved in the regulation of prostaglandin biosynthesis by glucocorticoids
143. Molecular determinants of glucocorticoid receptor function and tissue sensitivity to glucocorticoids
144. Prostaglandin endoperoxide H synthases (cyclooxygenases)-1 and 2
145. Molecular control of immune/inflammatory responses: Interactions between nuclear factor-kappa B and steroid receptor-signaling pathways
146. Transcriptional cross-talk, the second mode of steroid hormone receptor action
147. Rapid and transient induction of cyclooxygenase 2 by epidermal growth factor in human amnion-derived WISH cells
148. The effect of prenatal dexamethasone on fetal rat lung prostaglandin synthesis
149. Action of corticoisteroids in regulation of prostglandin biosynthesis in cultured fibroblasts
150. Hydrocortisone has a biphasic effect on rat gastric mucosal prostaglandin generation in vivo: Inhibition at low doses, stimulation at high doses
151. Regulation of prostaglandin synthesis during differentiation of cultured mouse myeloid leukemia cells
152. Effect of dexamethasone on cyclooxygenase activity in reno-medullary cells in culture
153. Characterization of the genomic structure, chromosomal location and promoter of human prostaglandin H synthase gene
154. Characterization of human prostaglandin H synthase genes
155. Interleukin I beta and dexamethasone regulate gene expression of prostaglandin H synthase via the NFkB pathway in human amnion derived WISH cells
156. Cyclic AMP response element mediates dexamethasone suppression of prostaglandin synthase-2 gene expression in human amnion derived WISH cells
157. A dual mechanism mediates repression of NFkB activity by glucocorticoids
158. IL-6 and IL-8 production by human amnion: Regulation by cytokines, growth factors, glucocorticoids, phorbol esters and bacterial lipopolysaccharide