The C-terminus of the γ2 chain but not of the β3 chain of laminin-332 is indirectly but indispensably necessary for integrin-mediated cell reactions

Experimental Cell Research

Volumn 314, Issue 3, 2008, Pages 489-497

  Navdaev, Alexei ^a   Heitmann, Vanessa ^b   deSantana Evangelista, Karla ^a   Mörgelin, Matthias ^c   Wegener, Joachim ^b   Eble, Johannes A ^a  

^a UNIVERSITY HOSPITAL MÜNSTER   (Germany)

^b UNIVERSITY OF MÜNSTER   (Germany)

^c LUND UNIVERSITY   (Sweden)

Author keywords

Adhesion; ECIS; Epithelial cell layer; Recognition site

Indexed keywords

INTEGRIN; KALININ;

ARTICLE; CARBOXY TERMINAL SEQUENCE; CELL ADHESION; CONTROLLED STUDY; ELECTRON MICROSCOPY; EXTRACELLULAR MATRIX; NONHUMAN; PRIORITY JOURNAL; PROTEIN INTERACTION;

EID: 38149046456     PISSN: 00144827     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.yexcr.2007.10.027     Document Type: Article

References (33)

1. Kalluri R. Basement membranes: structure, assembly and role in tumor angiogenesis. Nat. Rev., Cancer 3 (2003) 422-433
2. Erickson A.C., and Couchman J.R. Still more complexity in mammalian basement membranes. J. Histochem. Cytochem. 48 (2000) 1291-1306
3. Timpl R. Macromolecular organization of basement membranes. Curr. Opin. Cell Biol. 8 (1996) 618-624
4. Watt F.M. Role of integrins in regulating epidermal adhesion, growth and differentiation. EMBO J. 21 (2002) 3919-3926
5. Streuli C.H., and Edwards G.M. Control of normal mammary epithelial phenotype by integrins. J. Mammary Gland Biol. Neoplasia 3 (1998) 151-163
6. Colognato H., and Yurchenco P.D. Form and function: the laminin family of heterotrimers. Dev. Dyn. 218 (2000) 213-234
7. Beck K., and Brodsky B. Supercoiled protein motifs: the collagen triple helix and the α-helical coiled coil. J. Struct. Biol. 122 (1998) 17-29
8. Mizushima H., Koshikawa N., Moriyama K., Takamura H., Nagashima F., and Miyazaki K. Wide distribution of laminin-5 γ2 chain in basement membranes of various human tissues. Horm. Res. 50 (1998) 7-14
9. Rousselle P., Lunstrum G.P., Keene D.R., and Burgeson R.E. Kalinin: an epithelium-specific basement membrane adhesion molecule that is a component of anchoring filaments. J. Cell Biol. 114 (1991) 567-576
10. Aumailley M., El Khal A., Knöss N., and Tunggal L. Laminin 5 processing and its integration into the ECM. Matrix Biol. 22 (2003) 49-54
11. Gosh S., and Stack M.S. Proteolytic modification of laminins: functional consequences. Microsc. Res. Tech. 51 (2000) 238-246
12. Belkin A.M., and Stepp M.A. Integrins as receptors for laminins. Microsc. Res. Tech. 51 (2000) 280-301
13. Hynes R.O. Integrins: bidirectional, allosteric signaling machines. Cell 110 (2002) 673-687
14. 1 integrin: purification, regulation, and specific binding to laminin-5 and invasin in a mutually exclusive manner. Biochemist 37 (1998) 10945-10955
15. Delwel G.O., and Sonnenberg A. Laminin isoforms and their integrin receptor. In: Horton M.A. (Ed). Adhesion Receptors as Therapeutic Targets (1996), CRC Press, Boca Raton 9-36 Vol.
16. Nishiuchi R., Takagi J., Hayashi M., Ido H., Yagi Y., Sanzen N., Tsuji T., Yamada M., and Sekiguchi K. Ligand-binding specificities of laminin-binding integrins: a comprehensive survey of laminin-integrin interactions using recombinant α3β1, α6β1, α7β1 and α6β4 integrins. Matrix Biol. 25 (2006) 189-197
17. 1 integrin. J. Cell Biol. 117 (1992) 449-459
18. Sung U., O'Rear J.J., and Yurchenco P.D. Cell and heparin binding in the distal long arm of laminin: identification of active and cryptic sites with recombinant and hybrid glycoprotein. J. Cell Biol. 123 (1993) 1255-1268
19. 1 that promotes cell adhesion, spreading, and migration. J. Biol. Chem. 276 (2001) 33045-33053
20. 1 integrin binding. J. Biol. Chem. 279 (2004) 5184-5193
21. 1 binding and cell adhesion. Exp. Cell Res. 304 (2005) 317-327
22. Kariya Y., Tsubota Y., Hirosaki T., Mizushima H., Puzon-McLaughlin W., Takada Y., and Miyazaki K. Differential regulation of cellular adhesion and migration by recombinant laminin-5 forms with partial deletion or mutation within the G3 domain of α3 chain. J. Cell. Biochem. 88 (2003) 506-520
23. Deutzmann R., Aumailley M., Wiedemann H., Pysny W., Timpl R., and Edgar D. Cell adhesion, spreading and neurite stimulation by laminin fragment E8 depends on maintenance of secondary and tertiary structure in its rod and globular domain. Eur. J. Biochem. 191 (1990) 513-522
24. Dogic D., Hülsmann H., Sherman N., Fox J.W., Broermann R., Paulsson M., and Aumailley M. Cell adhesion to a population of laminin isoforms isolated from normal renal tissue. Matrix Biol. 18 (1999) 433-444
25. Rousselle P., Golbik R., van der Rest M., and Aumailley M. Structural requirement for cell adhesion to kalinin (laminin-5). J. Biol. Chem. 270 (1995) 13766-13770
26. Aumailley M., Mann K., von der Mark H., and Timpl R. Cell attachment properties of collagen type VI and Arg-Gly-Asp dependent binding to its α2(VI) and α3(VI) chains. Exp. Cell Res. 181 (1989) 463-474
27. Friedl P., and Bröcker E.-B. Reconstructing leukocyte migration in 3D extracellular matrix by time-lapse videomicroscopy and computer-assisted tracking. In: D'Ambrosio D., and Sinigaglia F. (Eds). Meth. Mol. Biol. vol. 239 (2004), Humana Press Inc., Totowa, NJ, USA 77-90
28. Giaever I., and Keese C.R. A morphological biosensor for mammalian cells. Nature 366 (1993) 591-592
29. Timpl R., Tisi D., Talts J.F., Andac Z., Sasaki T., and Hohenester E. Structure and function of laminin LG modules. Matrix Biol. 19 (2000) 309-317
30. Utani A., Nomizu M., Timpl R., Roller P.R., and Yamada Y. Laminin chain assembly. Specific sequences at the C-terminus of the long arm are required for the formation of specific double- and triple-stranded coiled-coil structures. J. Biol. Chem. 269 (1994) 19167-19175
31. Wegener J., Keese C.R., and Giaever I. Electric cell-substrate impedance sensing (ECIS) as a noninvasive means to monitor the kinetics of cell spreading to artificial surfaces. Exp. Cell Res. 259 (2000) 158-166
32. Keese C.R., Wegener J., Walker S.R., and Giaever I. Electric wound-healing assay for cells in vitro. Proc. Natl. Acad. Sci. U. S. A. 1001 (2004) 1554-1559
33. Ido H., Nakamur A., Kobayashi R., Ito S., Li S., Futaki S., and Sekiguchi K. The requirement of the glutamic acid residue at the third position from the carboxyl termini of the laminin γ chains in integrin binding by laminins. J. Biol. Chem. 282 (2007) 11144-11154