Proteolytic modification of laminins: Functional consequences

Microscopy Research and Technique

Volumn 51, Issue 3, 2000, Pages 238-246

  Ghosh, Supurna ^a   Stack, M Sharon ^a,b  

^a NORTHWESTERN UNIVERSITY   (United States)

^b NORTHWESTERN UNIVERSITY   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

CELLULAR RECEPTORS; EXTRACELLULAR MATRICES; HETEROTRIMERS; LAMININ; LIMITED PROTEOLYSIS; MULTI-DOMAINS; STRUCTURE-FUNCTION RELATIONSHIP;

CELL RECEPTOR; LAMININ; PROTEINASE;

ENZYME REGULATION; EXTRACELLULAR MATRIX; HUMAN; NONHUMAN; PRIORITY JOURNAL; PROTEIN ASSEMBLY; PROTEIN BINDING; PROTEIN DEGRADATION; PROTEIN DOMAIN; PROTEIN EXPRESSION; PROTEIN MODIFICATION; PROTEIN STRUCTURE; REVIEW; STRUCTURE ACTIVITY RELATION;

EID: 0034333019     PISSN: 1059910X     EISSN: None     Source Type: Journal    
DOI: 10.1002/1097-0029(20001101)51:3<238::AID-JEMT4>3.0.CO;2-3     Document Type: Review

References (93)

1. Aberdam D, Aguzzi A, Baudoin C, Galliano MF, Ortonne JP, Meneguzzi G. 1994. Developmental expression of nicein adhesion protein (laminin 5) subunits suggests multiple morphogenetic roles. Cell Ahd And Comm 2:115-129.
2. Andac Z, Sasaki T, Mann K, Brancaccio A, Deutzmann R, Timpl R. 1999. Analysis of heparin, alpha dystroglycan and sulfatide bidning to the G domain of the laminin alphα1 chain by site directed mutagenesis. J Mol Biol 287:253-264.
3. Aumailley M, Gerl M, Sonnenberg A, Deutzmann R, Timpl R. 1990a. Identification of the Arg-Gly-Asp sequnce in laminin A chain as a latent cell binding site being exposed in fragment P1. FEBS Lett 262:82-86.
4. Aumailley M, Timpl R, Sonnenberg A. 1990b. antibody to integrin alpha 6 subunit specifically inhibits cell binding to laminin fragment 8. Exp Cell Res 188:55-60.
5. Beck K, Hunter I, Engel J. 1990. Structure and function of laminin: anatomy of a mutidomain glycoprotein. FASEB J 4:148-160.
6. Beck K, Dixon TW, Engel J, Parry DAD. 1993. Ionic interactions in the coiled-coil domain of laminin determine the specificity of chain assembly. J Mol Biol 231:311-323.
7. Begovac PC, Hall DE, Shur BD. 1991. Laminin fragment E8 mediates PC12 cell neurite outgrowth by binding to cell surface beta 1, 4 galactosyltransferase. J Cell Biol 113:637-644.
8. Bilozur ME, Hay ED. 1988. Neural crest migration in 3D extracellular matrix utilizes laminin, fibronectin or collagen. Dev Biol 125:19-33.
9. Bushkin-Harav I, Littauer UZ. 1998. Involvement of the YIGSR sequence of laminin in protein tyrosine phosphorylation. FEBS Lett 424:243-247.
10. Chen ZL, Strickland S 1997. Neuronal death in the hippocampus is promoted by plasmin-catalyzed degradation of laminin. Cell 91: 917-925.
11. Corcoran ML, Kibbey MC, Kleinman HK, Wahl LM. 1995. Laminin SIKVAV peptide induction of monocyte/macrophage prostaglandin E2 and matrix metalloproteinases. J Biol Chem 270:10365-10368.
12. Deutzmann R, Aumailley M, Wiedemann H, Pysny W, Timpl R, Edgar D. 1990. Cell Adhesion, spreading, and neurite stimulation by laminin fragment E8 dependens on maintenance of secondary and tertiary structure in its rod and globular domain. Eur J Biochem 191:513-522.
13. Drago J, Nurcombe V, Barlett PF. 1991. Laminin through its long arm E8 fragment promotes the proliferation and differentiation of murine neuroepithelial cells in vitro. Exp Cell Res 192:256-265.
14. Edgar D, Timpl R, Thoenen H. 1984. The heparin binding domain of laminin is responsible for its effects on neurite outgrowth and neuronal survival. EMBO J 3:1463-1468.
15. Engel J. 1993. Structure and function of laminin. In: Rohrbach DH, Timpl R, editors. Molecular and cellular aspects of basement membranes. San Diego: Academic Press, p 147-176.
16. Engel J, Odermatt E, Engel A. 1981. Shapes, domain organization and flexibility of laminin and fibronectin, two multifunctional proteins of the extracellular matrix. J Mol Biol 150:97-120.
17. Engvall E, Wewer UM. 1996. Domains of laminin. J Cell Biochem 61:493-501.
18. Fridman R, Giaccone G, Kanemoto T, Martin GR, Gazdar AF, Mulshine JL. 1990. Reconstituted basement membrane (matrigel) and laminin can enhance the tumorigenicity and the drug resistance of small cell lung cancer cell lines. Proc Natl Acad Sci USA 87:6698-6702.
19. Galliano MF, Aberdam D, Aguzzi A, Ortonne JP, Meneguzzi G. 1995. Cloning and complete primary structure of the mouse laminin α3 chain. J Biol Chem 270:21820-21826.
20. Gee SH Montanaro F, Lindenbaum MH, Carbonetto S 1994. Dystroglycan alpha, a dystroglycan associated glycoprotein, is a functional agrin receptor. Cell 77:675-686.
21. Ghosh S, Brown R, Jones JCR, Ellerbroek SM, Stack MS. 2000. Urinary-type plasminogen activator (uPA) expression and uPA receptor localization are regulated by α3β1 integrin in oral keratinocytes. J Biol Chem 275:23869-23876.
22. Giannelli G, Falk-Marzillier J, Schiraldi O, Stetler-Stevenson WG, Quaranta V. 1997. Induction of cell migration by matrix metalloprotease-2 cleavage of laminin 5. Science 277:225-228
23. Goldfinger LE, Stack MS, Jones JC. 1998. Processing of laminin 5 and its functional consequences: Role of plasmin and tissue-type plasminogen activator. J Cell Biol 141:255-265.
24. Goldfinger LE, Hopkinson SB, deHart GW, Collawn S, Couchman JR, Jones JC. 1999. The α3 laminin subunit, α6β4 and α3β1 integrin coordinately regulate wound healing in cultured epithelial cells and in the skin. J Cell Sci 112:2615-2629.
25. Goodman SL, Risse G, von der Mark K 1989. The E8 subfragment of laminin promotes locomotion of myoblasts over extracellular matrix. J Cell Biol 109:799-809.
26. Graf J, Ogle RC, Robey GR, Sasaki M, Martin GR, Yamada Y, Kleinman HK.1987a. A pentapeptide from the laminin B1 chain mediates cell adhesion and binds the 67,000 laminin receptor. Biochemistry 26:6896-6900.
27. Graf J, Iwamoto Y, Sasaki M, Martin GR, Kleinman HK, Robey GR, Yamada Y. 1987b. Identification of an amino acid sequence in laminin mediating cell attachment, chemotaxis and receptor binding. Cell 48:89-996.
28. Grant DS, Kibbey MC, Kinsella JL, Cid MC, Kleinman HK. 1994. The role of basement membrane in angiogenesis and tumor growth. Pathol Res Pract 190:854-863.
29. Hadley MA, Weeks BS, Kleinman HK, Dym M. 1990. Laminin promotes formation of cord-like structures by sertoli cells in vitro. Dev Biol 140:318-327.
30. Iwamoto Y, Robey FA, Graf J, Sasaki M, Kleinman HK, Yamada Y, Martin GR. 1987. YIGSR, a synthetic laminin pentapeptide, inhibits experimental metastasis formation. Science 238:1132-1134.
31. Iwamoto y, Nomizu M, Yamada Y, Ito Y, Tanaka K, Sugioka Y. 1996. Inhibition of angiogenesis, tumor growth and experimental metastasis of human fibrosarcoma cells Ht1080 by a multimeric form of the laminin sequence Tyr-Ile-Gly-Ser-Arg (YIGSR). Br J Cancer 73:589-595.
32. Jones JC, Hopkinson SB, Goldfinger LE. 1998. Structure and assembly of hemidesmosomes. Bioessays 20:488-494.
33. Kanemoto T, Reich R, Royce L, Greatorex D, Adler SH, Shiraishi N, Martin GR, Yamada Y, Kleinman HK. 1990. Identification of an amino acid sequence in laminin mediating cell attachment, chemotaxis and receptor binding. Proc Natl Acad Sci USA 87:2279-2283.
34. Khan KMF, Falcone DJ. 1997. Role of laminin in matrix induction of macrophage urokinase-type plasminogen activator and 92-kDa metalloproteinase expression. J Biol Chem 272:8270-8275.
35. Kim WH, Schnaper W, Nomizu M, Yamada Y, Kelinman HK. 1994. Apoptosis in human fibrosarcoma cells is induced by a mutimeric synthetic Tyr-Ile-Gly-Ser-Arg (YIGSR)-containing poplypeptide from laminin. Cancer Res 54:5005-5010.
36. Kim WH, Nomizu M, Song SY, Tanaka K, Kuratomi Y, Kelinman HK, Yamada Y. 1998. Laminin alpha 1 chain sequence Leu-Gln-Val-Gln-Leu-Ser-Ile-Arg (LQVQLSIR) enhances murine melanoma cell metastasis. Int J Cancer 77:632-639.
37. Klein G, Langegger M, Timpl R, Ekblom P. 1988. Role of laminin A chain in the development of epithelial cell polarity. Cell 55:331-341
38. Kleinman H, Cannon FB, Laurie GW, Hassell JR, Aumailley M, Terranova VP, Martin GR, DuBois-Dalcq M. 1985. Biological activities of laminin. J Cell Biochem 27:317-325.
39. Kleinman HK, Graf J, Iwamoto Y; Sasaki M, Schasteen CS, Yamada Y, Martin GR, Robey FA. 1989. Identification of a second active site in laminin for promotion of cell adhesion and migration and inhibition of in vivo melanoma lung colonization. Arch Biochem Biophys 272:39-45.
40. Kleinman HK, Weeks BS, Schnaper HW, Kibbey MC, Yamamura K, Grant DS. 1993. The laminins: a family of basement membrane glycoproteins important in cell differentiation and tumor metastasis. Vitam Horm 47:161-186.
41. Koshikawa N, Gianelli G, Cirulli V, Miyazaki K, Quaranta V. 2000. Role of cell surface metalloprotease Mti-MMP in epithelial cell migration over laminin 5. J Cell Biol 148:615-624.
42. Langhofer M, Baker SE, Hopkinson SE, Jones JCR. 1994. Hemidesmosomes: form, function and assembly. In: Collins JE, Garrod DR, editors. Molecular biology of desmosomes and hemidesmosomes. Austin, TX: R.G. Landis Co., p 69-86.
43. Lengyel R, Gum R, Stepp E, Jurarez J, Wang H, Boyd D. 1996. Regulation of urokinase-type plasminogen activator expression by an ERK1-dependent signaling pathway in a squamous cell carcinoma cell line. J Cell Biochem 61:430-443.
44. Malinda KM, Kleinman HK. 1996. The laminins. Int J Biochem Cell Biol 28:957-959.
45. Marinkovich MP, Lunstrum GP, Burgeson RE. 1992. The anchoring filament protein kalinin is synthesized and secreted as a high molecular weight precursor. J Biol Chem 267:17900-17906.
46. Matsui C, Wang CK, Nelson CF, Bauer EA, Hoeffler WK. 1995. The assembly of laminin 5 subunits. J Biol Chem 270:23496-23503.
47. Moser TL, Enghild JJ, Pizzo SV, Stack MS. 1993. The extracellular matrix proteins laminin and fibronectin contain binding domains for human plasminogen and tissue plasminogen activator. J Biol Chem 268:18917-1823.
48. Mungan U, Kirkali G, Celebi I, Kirkali Z. 1996. Significance of serum laminin Pl values in patients with transitional cell carcinoma of the bladder. Urology 48:496-500.
49. Muschler J, Lochter A, Roskelley CD, Yurchenco P, Bissell MJ. 1999. Division of labor among the alpha6beta4 integrin, beta 1 integrins, and an E3 laminin receptor to signal morphogenesis and beta casein expression in mammary epithelial cells. Mol Biol Cell 10:2817-2828.
50. Nakagami Y, Abe K, Nishiyama N, Matsuki N. 2000. Laminin degradation by plasmin regulates long term potentiation. J Neurosci 20:2003-2010.
51. Nakajima C, Shimojo N, Naka K, Okuda K, Yamamoto M, Fujii S. 1991. Clinical significance of urinary laminin P1 in diabetic patients. J Diabet Complications 5:197-198.
52. Nomizu M, Otaka A, Utani A, Roller PP, Yamada Y. 1994. Assembly of synthetic laminin peptides into a triple stranded coiled coil structure. JBC 269:30386-30392.
53. Ott U Odermatt E, Engel J, Furthmayr H, Timpl R. 1982. Protease resistance and conformation of laminin. Eur J Biochem 123:63-72.
54. Papadopoulos V, Dym M. 1994. Sertoli cell differentiation on basement membrane is mediated by the c-fos protooncogene. Proc Natl Acad Sci USA 91:7027-7031.
55. Paulsson M, Deutzmann R, Timpl R, Dalzoppo D, Odermatt E, Engel J. 1985. Evidence for coiled-coil α helical regions in the long arm of laminin. EMBO J 4:309-316.
56. Pyke C, Kristensen P, Ralfkiaer E, Grondahl-Hansen J, Eriksen J, Blasi F, Dano K. 1994. The gamma2 chain of kalinin/laminin5 is preferentially expressed in invading malignant cells in human cancers. Am J Pathol 145:82-91.
57. Reich R, Blumenthal RI, Liscovitch M. 1995. Role of phospholipase D in laminin-induced production of gelatinase A (MMP-2) in metastatic cells. Clin Exp Metast 13:134-140.
58. Richard BL, Nomizu M, Yamada Y, Kleinman HK. 1996. Identification of synthetic peptides derived from laminin alpha1 and alpha2 chains with cell type specificity for neurite outgrowth. Exp Cell Res 228:98-105.
59. Rohde H, Bachinger HP, Timpl R. 1980. Characterization of pepsin fragments of laminin in a tumor basement membrane. Evidence for the existence of related proteins. Hoppe Seyler Z Physiol Chem 361:1651-1660.
60. Rouselle P, Lunstrum GP, Keene DR, Burgeson RE. 1991. Kalinin: an epithelium specific basement membrane adhesion molecule that is a component of anchoring filaments. J Cell Biol 114:567-576.
61. Royce LS, Martin GR, Kleinman HK. 1992. Induction of an invasive phenotype in benign tumor cells with a laminin A chain synthetic peptide. Invas Metast 12:149-155.
62. Ryan MC, Tizard R, VanDevanter DR, Burgeson RE. 1994. Cloning of the LamA3 gene encoding the alpha3 chain of the adhesive ligand apiligrin. J Biol Chem 269:22779-22787.
63. Sasaki M, Kleinman HK, Huber H, Deutzmann R, Yamada Y. 1988. Laminin, a mutidomain protein. The A chain ahas unique globular domain and homology with the basement membrane proteoglycan and the laminin B chains. J Biol Chem 263:16536-16544.
64. Segarra A, Simo R, Masmiquel L, Segura RM, Fonolossa V, Huguet P, Majo J, Piera L. 2000. serum concentrations of laminin P1 in thrombotic microangiopathy:usefulness as an index of activity and prognostic value. J Am Soc Nephrol 11:434-443.
65. Sonnenberg A , Linders CJ, Modderman PW, Damsky CH, Aumailley M, Timpl R. 1990. Integrin recognition of different cell binding fragments of laminin (P1, E3, E8) and evidence that alpha6beta1 but not alpha6beta4 functions as a major receptor for fragment E8. J Cell Biol 110:2145-2155.
66. Sonohara S, Mira-y-Lopez R, Brentani MM. 1998. Laminin and estradiol regulation of the plasminogen activator system in MCF-7 breast-carcinoma cells. Int J Cancer 76:77-85.
67. Sorokin L, Sonnenberg A, Aumailley M, Timpl R, Ekblom P. 1990. Recognition of the laminin E8 cell binding site by an integrin possessing the alpha 6 subunit is essential for epithelial polarization in developing kidney tubules. J Cell Biol 111:1265-1273.
68. Stack MS, Gray RD, Pizzo SV. 1991. Modulation of plasminogen activation and type IV collagenase activity by a synthetic peptide derived from the laminin A chain. Biochemistry 30:2073-2077:
69. Stack MS, Gray RD, Pizzo SV. 1993. Modulation of murine B16F10 melanoma plasminogen activator production by a synthetic peptide derived from the laminin A chain. Cancer Res 53:1998-2004.
70. Stack MS, Pizzo SV. 1994. The effect of substituted laminin A chain-derived peptides on the conformation and activation kinetics of plasminogen. Arch Biochem Biophys 309:117-122.
71. Steiner DF, Smeekens SP, Ohagi S, Chan SJ. 1992. The new enzymology of precursor processing endoproteases. J Biol Chem 267: 23435-23438.
72. Streuli CH, Schmidhauser C, Bailey N, Yurchenco P, Skubitz AP, Roskelley C, Bissell MJ. 1995. Laminin mediated tissue-specific gene expression in mammary epithelia. J Cell Biol 129:591-603.
73. Talts JF, Timpl R. 1999. Mutation of a basic sequence in the laminin alpha2LG3 module leads to a lack of proteolytic processing and has different effects on beta1 integrin-mediated cell adhesion and alpha dystroglycan binding. FEBS Lett 58:319-323.
74. Talts JF, Mann K, Yamada Y, Timpl R. 1998. Structural analysis and proteolytic processing of recombinant G domain of mouse laminin alpha2 chain. FEBS Lett 426:71-76.
75. Tashiro K, Sphel GC, Weeks B, Sasaki M, Martin GR, Kleinman HK, Yamada Y. 1989. A synthetic peptide containing the IKVAV sequence from the A chain of laminin mediates cell attachement, migration and neurite out growth. J Biol Chem 264:16174-16182.
76. Tillet E, Mann K, Nischt R, Pan TC, Chu ML, Timpl R. 1995. Eur JBiochem 228:160-168.
77. Timpl R, Brown JC. 1994. The laminins. Matrix Biol 14:275-281.
78. Tsirka SE, Rogove AD, Stricland S. 1996. Neuronal cell death and tPA. Nature 384:123-124.
79. Timpl R, Rohde H, Gehron R, Robey P, Rennard SI, Foidart JRI, Martin GR. 1979. Laminin: a glycoprotein from basement membranes. J Biol Chem 254:9933-9937.
80. Tsirka SE, Bugge TH, Degen JL, Stricland S. 1997a. Neuronal death in the central nervous system demonstrates a non-fibrin substrate for plasmin. Proc Natl Acad Sci USA 94:9779-9781.
81. Tsirka SE, Rogove AD, Bugge TH, Degen JL, Stricland S. 1997b. An extracellular proteolytic cascade promotes neuronal degeneration in the mouse hippocampus. J Neurosci 17:543-552.
82. Turpeenniemi-Hujanen T, Thorgeirsson UP, Rao CN, Liotta LA. 1986. Laminin increases the release of type IV collagenase from malignant cells. J Biol Chem 261:1883-1889.
83. Utani A, Nomizu M, Timpl R, Roller PP, Yamada Y. 1994. Laminin chain assembly. Specific sequences at the C terminus of the long are required for the formation of specific double and triple stranded coiled stranded coiled-coil structures. JBC 269:19167-19175.
84. Verrando P, His BL, Yeh CJ, Serieys N, Ortonne JP. 1987. Monoclonal antibody GB3, a new probe for the study of human basement membranes and hemidesmosomes. Exp Cell Res 170:116-128.
85. von der Mark H, Durr J, Sonnenberg A, von der Mark K, Deutzmann R, Goodman SL. 1991. Skeletal myoblasts utilize a novel beta1 series integrin and not alpha 6 beta 1 for binding to the E8 and T8 fragments of laminin. J Biol Chem 266:23593-23601.
86. Weeks BS, Nomizu M, Ramchandran RS, Yamada Y, Klienman HK. 1998. Laminin-1 and the RKRLQVQLSIRT laminin-1 alpha1 globular domain peptide stimulate matrix metalloproteinase secretion by PC12 cells. Exp Cell Res 243:375-382.
87. Yamada Y, Kleinman HK. 1992. Functional domains of cell adhesion molecules. Curr Opin Cell Biol 4:819-823.
88. Yamamura K, Kibbey MC, Jun SH, Kleinman HK. 1993. Effect of Matrigel and laminin peptide YIGSR on tumor growth and metastasis. Sem Cancer Biol 4:259-265.
89. Yoshida N, Ishii E, Nomizu M, Yamada Y, Mohri S, Kinukawa N, Matsuzaki A, Oshima K, Kara T, Miyazaki S. 1999. The laminin derived peptide YIGSR (Tyr-Ile-Gly-Ser-Arg) inhibits human pre_B leukemic cell growth and dissemination to organs in SCID mice. Br J Cancer 80:1898-1904.
90. Yurchenco PD, Cheng YS, Schittny JC. 1990. Heparin modulation of laminin polymerization. J Biol Chem 265:3981-3991.
91. Yurchenco PD, Sung U, Ward MD, Yamada Y, O'Rear JJ. 1993. Recombinant laminin G domain mediates myoblast adhesion and heparin binding. J Biol Chem 268:8356-8365.
92. Yurchenco PD, Quan Y, Colognato H, Mathus T, Harrison D, Yamada Y, O'Rear JJ. 1997. The α chain of laminin 1 is independently secreted and drives secretion of its β- and γ- partners. Proc Natl Acad Sci USA 94:10189-10194.
93. Ziober BL, Lin C-S, Kramer RH. 1996. Laminin binding integrins in tumor progression and metastasis. Sem Cancer Biol 7:119-128.