Use of manometric temperature measurement (MTM) and SMART™ freeze dryer technology for development of an optimized freeze-drying cycle

Journal of Pharmaceutical Sciences

Volumn 96, Issue 12, 2007, Pages 3402-3418

  Gieseler, Henning ^a,c   Kramer, Tony ^b   Pikal, Michael J ^a  

^a UNIVERSITY OF CONNECTICUT   (United States)

^b PFIZER INC   (United States)

^c UNIVERSITY OF ERLANGEN NUREMBERG   (Germany)

Author keywords

Formulation; Freeze drying lyophilization; Mathematical model; Processing; Proteins

Indexed keywords

ARTICLE; DRUG FORMULATION; FREEZE DRYING; MANOMETRY; MATHEMATICAL ANALYSIS; MEDICAL INSTRUMENTATION; MEDICAL TECHNOLOGY;

EID: 38149002933     PISSN: 00223549     EISSN: 15206017     Source Type: Journal    
DOI: 10.1002/jps.20982     Document Type: Article

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