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Volumn 27, Issue 3, 2008, Pages 274-284

Ajuba negatively regulates the Wnt signaling pathway by promoting GSK-3β-mediated phosphorylation of β-catenin

Author keywords

catenin; Ajuba; GSK 3 ; Phosphorylation; Wnt

Indexed keywords

AJUBA PROTEIN; BETA CATENIN; COMPLEMENTARY DNA; GLYCOGEN SYNTHASE KINASE 3BETA; LUCIFERASE; RETROVIRUS VECTOR; RNA; SMALL INTERFERING RNA; UNCLASSIFIED DRUG; WNT PROTEIN;

EID: 38049174277     PISSN: 09509232     EISSN: 14765594     Source Type: Journal    
DOI: 10.1038/sj.onc.1210644     Document Type: Article
Times cited : (49)

References (26)
  • 1
    • 9244233875 scopus 로고    scopus 로고
    • Role of a BCL9-related b-catenin-binding protein, B9L, in tumorigenesis induced by aberrant activation of Wnt signaling
    • Adachi S, Jigami T, Yasui T, Nakano T, Ohwada S, Omori Y et al. (2004). Role of a BCL9-related b-catenin-binding protein, B9L, in tumorigenesis induced by aberrant activation of Wnt signaling. Cancer Res 64: 8496-8501.
    • (2004) Cancer Res , vol.64 , pp. 8496-8501
    • Adachi, S.1    Jigami, T.2    Yasui, T.3    Nakano, T.4    Ohwada, S.5    Omori, Y.6
  • 2
    • 0034644526 scopus 로고    scopus 로고
    • Linking colorectal cancer to Wnt signaling
    • Bienz M, Clevers H. (2000). Linking colorectal cancer to Wnt signaling. Cell 103: 311-320.
    • (2000) Cell , vol.103 , pp. 311-320
    • Bienz, M.1    Clevers, H.2
  • 3
    • 0031456158 scopus 로고    scopus 로고
    • Wnt signaling: A common theme in animal development
    • Cadigan KM, Nusse R. (1997). Wnt signaling: a common theme in animal development. Genes Dev 11: 3286-3305.
    • (1997) Genes Dev , vol.11 , pp. 3286-3305
    • Cadigan, K.M.1    Nusse, R.2
  • 4
    • 0031966041 scopus 로고    scopus 로고
    • LIM domains: Multiple roles as adapters and functional modifiers in protein interactions
    • Dawid IB, Breen JJ, Toyama R. (1998). LIM domains: multiple roles as adapters and functional modifiers in protein interactions. Trends Genet 14: 156-162.
    • (1998) Trends Genet , vol.14 , pp. 156-162
    • Dawid, I.B.1    Breen, J.J.2    Toyama, R.3
  • 5
    • 0035942736 scopus 로고    scopus 로고
    • Duplexes of 21-nucleotide RNAs mediate RNA interference in cultured mammalian cells
    • Elbashir SM, Harborth J, Lendeckel W, Yalcin A, Weber K, Tuschln T. (2001). Duplexes of 21-nucleotide RNAs mediate RNA interference in cultured mammalian cells. Nature 411: 494-498.
    • (2001) Nature , vol.411 , pp. 494-498
    • Elbashir, S.M.1    Harborth, J.2    Lendeckel, W.3    Yalcin, A.4    Weber, K.5    Tuschln, T.6
  • 6
    • 0037031887 scopus 로고    scopus 로고
    • Wnt-3A/b-catenin signaling induces transcription from the LEF-1 promoter
    • Filali M, Cheng N, Abbott D, Leontiev V, Engelhardt JF. (2002). Wnt-3A/b-catenin signaling induces transcription from the LEF-1 promoter. J Biol Chem 277: 33398-33410.
    • (2002) J Biol Chem , vol.277 , pp. 33398-33410
    • Filali, M.1    Cheng, N.2    Abbott, D.3    Leontiev, V.4    Engelhardt, J.F.5
  • 8
    • 0033045690 scopus 로고    scopus 로고
    • Ajuba, a novel LIM protein, interacts with Grb2, augments mitogen-activated protein kinase activity in fibroblasts, and promotes meiotic maturation of Xenopus oocytes in a Grb2- and Ras-dependent manner
    • Goyal RK, Lin P, Kanungo J, Payne AS, Muslin AJ, Longmore GD. (1999). Ajuba, a novel LIM protein, interacts with Grb2, augments mitogen-activated protein kinase activity in fibroblasts, and promotes meiotic maturation of Xenopus oocytes in a Grb2- and Ras-dependent manner. Mol Cell Biol 19: 4379-4389.
    • (1999) Mol Cell Biol , vol.19 , pp. 4379-4389
    • Goyal, R.K.1    Lin, P.2    Kanungo, J.3    Payne, A.S.4    Muslin, A.J.5    Longmore, G.D.6
  • 9
    • 0032473355 scopus 로고    scopus 로고
    • Axin, a negative regulator of the Wnt signaling pathway, forms a complex with GSK-3b and b-catenin and promotes GSK-3b-dependent phosphorylation of b-catenin
    • Ikeda S, Kishida S, Yamamoto H, Murai H, Koyama S, Kikuchi A. (1998). Axin, a negative regulator of the Wnt signaling pathway, forms a complex with GSK-3b and b-catenin and promotes GSK-3b-dependent phosphorylation of b-catenin. EMBO J 17: 1371-1384.
    • (1998) EMBO J , vol.17 , pp. 1371-1384
    • Ikeda, S.1    Kishida, S.2    Yamamoto, H.3    Murai, H.4    Koyama, S.5    Kikuchi, A.6
  • 10
    • 0033782919 scopus 로고    scopus 로고
    • Ajuba, a cytosolic LIM protein, shuttles into the nucleus and affects embryonal cell proliferation and fate decisions
    • Kanungo J, Pratt SJ, Marie H, Longmore GD. (2000). Ajuba, a cytosolic LIM protein, shuttles into the nucleus and affects embryonal cell proliferation and fate decisions. Mol Biol Cell 11: 3299-3313.
    • (2000) Mol Biol Cell , vol.11 , pp. 3299-3313
    • Kanungo, J.1    Pratt, S.J.2    Marie, H.3    Longmore, G.D.4
  • 11
    • 10044280582 scopus 로고    scopus 로고
    • Interaction and functional cooperation between the LIM protein FHL2, CBP/p300, and b-catenin
    • Labalette C, Renard CA, Neuveut C, Buendia MA, Wei Y. (2004). Interaction and functional cooperation between the LIM protein FHL2, CBP/p300, and b-catenin. Mol Cell Biol 24: 10689-10702.
    • (2004) Mol Cell Biol , vol.24 , pp. 10689-10702
    • Labalette, C.1    Renard, C.A.2    Neuveut, C.3    Buendia, M.A.4    Wei, Y.5
  • 12
    • 11144353713 scopus 로고    scopus 로고
    • Acetylation of b-catenin by p300 regulates b-catenin-Tcf4 interaction
    • Levy L, Wei Y, Labalette C, Wu Y, Renard CA, Buendia MA et al. (2004). Acetylation of b-catenin by p300 regulates b-catenin-Tcf4 interaction. Mol Cell Biol 24: 3404-3414.
    • (2004) Mol Cell Biol , vol.24 , pp. 3404-3414
    • Levy, L.1    Wei, Y.2    Labalette, C.3    Wu, Y.4    Renard, C.A.5    Buendia, M.A.6
  • 13
    • 0033517102 scopus 로고    scopus 로고
    • Axin and Frat1 interact with dvl and GSK, bridging Dvl to GSK in Wnt-mediated regulation of LEF-1
    • Li L, Yuan H, Weaver CD, Mao J, Farr III GH, Sussman DJ et al. (1999). Axin and Frat1 interact with dvl and GSK, bridging Dvl to GSK in Wnt-mediated regulation of LEF-1. EMBO J 18: 4233-4240.
    • (1999) EMBO J , vol.18 , pp. 4233-4240
    • Li, L.1    Yuan, H.2    Weaver, C.D.3    Mao, J.4    Farr III, G.H.5    Sussman, D.J.6
  • 14
    • 18244427021 scopus 로고    scopus 로고
    • Low-density lipoprotein receptor-related protein-5 binds to Axin and regulates the canonical Wnt signaling pathway
    • Mao J, Wang J, Liu B, Pan W, Farr III GH, Flynn C et al. (2001). Low-density lipoprotein receptor-related protein-5 binds to Axin and regulates the canonical Wnt signaling pathway. Mol Cell 7: 801-809.
    • (2001) Mol Cell , vol.7 , pp. 801-809
    • Mao, J.1    Wang, J.2    Liu, B.3    Pan, W.4    Farr III, G.H.5    Flynn, C.6
  • 15
    • 0037078329 scopus 로고    scopus 로고
    • The LIM-only protein FHL2 interacts with b-catenin and promotes differentiation of mouse myoblasts
    • Martin B, Schneider R, Janetzky S, Waibler Z, Pandur P, Kuhl M et al. (2002). The LIM-only protein FHL2 interacts with b-catenin and promotes differentiation of mouse myoblasts. J Cell Biol 159: 113-122.
    • (2002) J Cell Biol , vol.159 , pp. 113-122
    • Martin, B.1    Schneider, R.2    Janetzky, S.3    Waibler, Z.4    Pandur, P.5    Kuhl, M.6
  • 16
    • 0029964851 scopus 로고    scopus 로고
    • Signal transduction through b-catenin and specification of cell fate during embryogenesis
    • Miller JR, Moon RT. (1996). Signal transduction through b-catenin and specification of cell fate during embryogenesis. Genes Dev 10: 2527-2539.
    • (1996) Genes Dev , vol.10 , pp. 2527-2539
    • Miller, J.R.1    Moon, R.T.2
  • 17
    • 0034053069 scopus 로고    scopus 로고
    • Wnt signaling in oncogenesis and embryogenesis - a look outside the nucleus
    • Peifer M, Polakis P. (2000). Wnt signaling in oncogenesis and embryogenesis - a look outside the nucleus. Science 287: 1606-1609.
    • (2000) Science , vol.287 , pp. 1606-1609
    • Peifer, M.1    Polakis, P.2
  • 18
    • 14744267471 scopus 로고    scopus 로고
    • The LIM protein Ajuba influences p130Cas localization and Rac1 activity during cell migration
    • Pratt SJ, Epple H, Ward M, Feng Y, Braga VM, Longmore GD. (2005). The LIM protein Ajuba influences p130Cas localization and Rac1 activity during cell migration. J Cell Biol 168: 813-824.
    • (2005) J Cell Biol , vol.168 , pp. 813-824
    • Pratt, S.J.1    Epple, H.2    Ward, M.3    Feng, Y.4    Braga, V.M.5    Longmore, G.D.6
  • 22
    • 0034661142 scopus 로고    scopus 로고
    • Inhibition of Wnt signaling by ICAT, a novel b-catenin-interacting protein
    • Tago K, Nakamura T, Nishita M, Hyodo J, Nagai S, Murata Y et al. (2000). Inhibition of Wnt signaling by ICAT, a novel b-catenin-interacting protein. Genes Dev 14: 1741-1749.
    • (2000) Genes Dev , vol.14 , pp. 1741-1749
    • Tago, K.1    Nakamura, T.2    Nishita, M.3    Hyodo, J.4    Nagai, S.5    Murata, Y.6
  • 24
    • 0033119801 scopus 로고    scopus 로고
    • b-catenin regulates expression of cyclin D1 in colon carcinoma cells
    • Tetsu O, McCormick F. (1999). b-catenin regulates expression of cyclin D1 in colon carcinoma cells. Nature 398: 422-426.
    • (1999) Nature , vol.398 , pp. 422-426
    • Tetsu, O.1    McCormick, F.2
  • 25
    • 0037343952 scopus 로고    scopus 로고
    • Wg/Wnt signal can be transmitted through arrow/LRP5, 6 and Axin independently of Zw3/Gsk3b activity
    • Tolwinski NS, Wehrli M, Rives A, Erdeniz N, DiNardo S, Wieschaus E. (2003). Wg/Wnt signal can be transmitted through arrow/LRP5, 6 and Axin independently of Zw3/Gsk3b activity. Dev Cell 4: 407-418.
    • (2003) Dev Cell , vol.4 , pp. 407-418
    • Tolwinski, N.S.1    Wehrli, M.2    Rives, A.3    Erdeniz, N.4    DiNardo, S.5    Wieschaus, E.6
  • 26
    • 0038187682 scopus 로고    scopus 로고
    • Identification of the LIM protein FHL2 as a coactivator of b-catenin
    • Wei Y, Renard CA, Labalette C, Wu Y, Levy L, Neuveut C et al. (2003). Identification of the LIM protein FHL2 as a coactivator of b-catenin. J Biol Chem 278: 5188-5194.
    • (2003) J Biol Chem , vol.278 , pp. 5188-5194
    • Wei, Y.1    Renard, C.A.2    Labalette, C.3    Wu, Y.4    Levy, L.5    Neuveut, C.6


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.