PLA2 signaling is involved in calpain-mediated degradation of synaptic dihydropyrimidinase-like 3 protein in response to NMDA excitotoxicity

Neuroscience Letters

Volumn 430, Issue 3, 2008, Pages 197-202

  Kowara, Renata ^a   Moraleja, Kristoffer Laser ^a   Chakravarthy, Balu ^a  

^a NATIONAL RESEARCH COUNCIL CANADA   (Canada)

Author keywords

Calpain; CRMP 4; DPYSL3; DRP 3; Neurotoxicity; NMDA; PLA2

Indexed keywords

CALPAIN; COLLAPSIN RESPONSE MEDIATOR PROTEIN; CYCLIC AMP; CYCLOOXYGENASE 2 INHIBITOR; DIHYDROPYRIMIDINASE LIKE 3 PROTEIN; FORSKOLIN; ISOBUTYLMETHYLXANTHINE; N METHYL DEXTRO ASPARTIC ACID; PHOSPHOLIPASE A2; UNCLASSIFIED DRUG;

APOPTOSIS; ARTICLE; BRAIN CELL; CELL VIABILITY; CONTROLLED STUDY; ENZYME ACTIVATION; ENZYME INHIBITION; EXCITOTOXICITY; NEUROTOXICITY; NONHUMAN; PRIORITY JOURNAL; PROTEIN DEGRADATION; PROTEIN FUNCTION; RAT;

ADENYLATE CYCLASE; ANIMALS; CALPAIN; CELLS, CULTURED; CEREBRAL CORTEX; CYCLIC AMP; CYCLIC AMP-DEPENDENT PROTEIN KINASES; CYCLOOXYGENASE 2 INHIBITORS; ENZYME ACTIVATION; ENZYME INHIBITORS; EXCITATORY AMINO ACID AGONISTS; N-METHYLASPARTATE; NERVE TISSUE PROTEINS; NEURONS; NEUROTOXINS; PHOSPHOLIPASES A2; RATS; SIGNAL TRANSDUCTION; SYNAPSES;

EID: 38049134367     PISSN: 03043940     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.neulet.2007.10.036     Document Type: Article

References (32)

1. Averna M., De Tullio R., Passalacqua M., Salamino F., Pontremoli S., and Melloni E. Changes in intracellular calpastatin localization are mediated by reversible phosphorylation. Biochem. J. 354 (2001) 25-30
2. Banko J.L., Hou L., and Klann E. NMDA receptor activation results in PKA- and ERK-dependent Mnk1 activation and increased eIF4E phosphorylation in hippocampal area CA1. J. Neurochem. 91 (2004) 462-470
3. Carlson N.G. Neuroprotection of cultured cortical neurons mediated by cyclooxygenase-2 inhibitor APHS can be reversed by prostanoid. J. Neurosci. Res. 71 (2003) 79-88
4. Carrier R.L., Ma T.C., Obrietan K., and Hoyt K.R. A sensitive and selective assay of neuronal degeneration in cell culture. J. Neurosci. Methods 154 (2006) 239-244
5. Chen Ch., and Bazan N.G. Endogenous PGE2 regulates membrane excitability and synaptic transmission in hippocampal CA1 pyramidal neurons. J. Neurophysiol. 93 (2005) 929-941
6. 2 potentiates glutamate-induced calcium increase and cell death in primary neuronal cultures. J. Neurosci. Res. 67 (2002) 634-645
7. Franken S., Junghans U., Rosslenbroich V., Baader S.L., Hoffmann R., Gieselmann V., Viebahn C., and Kappler J. Collapsin response mediator proteins of neonatal rat brain interact with chondroitin sulfate. J. Biol. Chem. 278 (2002) 3241-3250
8. Gendron T.F., Brunette E., Mealing G.A., Nguyen A., Tauskela J.S., and Morley P. Opposing effects of cyclooxygenase-2 selective inhibitors on oxygen-glucose deprivation-induced neurotoxicity. Eur. J. Pharmacol. 493 (2004) 45-55
9. Hewett S.J., Uliasz T.F., Vidwans A.S., and Hewett J.A. Cyclooxygenase-2 contributes to N-metyl-d-aspartate-mediated neuronal cell death in primary cortical neurons. J. Pharmacol. Exp. Ther. 293 (2000) 417-425
10. 2 EP1 receptors: downstream effectors of COX-2 neurotoxicity. Nat. Med. 12 (2006) 225-229
11. 2-mediated neuronal cell death involves glutamate ionotropic receptors. Neuroreport 13 (2002) 1963-1966
12. 2, platelet-activating factor, and cyclooxygenase-2 in neuronal cells in culture. Neurosci. Lett. 338 (2003) 164-168
13. 2 toxicity. J. Neurochem. 95 (2005) 466-474
14. Kowara R., Moraleja K.L., and Chakravarthy B. Involvement of nitric oxide synthase and ROS-mediated activation of L-type voltage-gated Ca(2+) channels in NMDA-induced DPYSL3 degradation. Brain Res. 1119 (2006) 40-49
15. Leonard A.S., and Hell J.W. Cyclic AMP-dependent protein kinase and protein kinase C phosphorylate N-methyl-d-aspartate receptors at different sites. J. Biol. Chem. 272 (1997) 12107-12115
16. Llansola M., Sanchez-Perez A.M., Montoliu C., and Felipo V. Modulation of NMDA receptor function by cyclic AMP in cerebellar neurones in culture. J. Neurochem. 91 (2004) 591-599
17. Lopez-Picon F.R., Kukko-Lukjanov T.K., and Holopainen I.E. The calpain inhibitor MDL-28170 and the AMPA/KA receptor antagonist CNQX inhibit neurofilament degradation and enhance neuronal survival in kainic acid-treated hippocampal slice cultures. Eur. J. Neurosci. 23 (2006) 2686-2694
18. Manabe Y., Anrather J., Kawano T., Miwa K., Zhou P., Ross M.E., and Iadecola C. Prostanoids, nor reactive oxygen species, mediate COX-2 dependent neurotoxicity. Ann. Neurol. 55 (2004) 668-675
19. 2: a necessary step in long-term potentiation?. Proc. Natl. Acad. Sci. U.S.A. 88 (1991) 1893-1897
20. 2 synthesis and lipid peroxidation after in vivo activation of N-methyl-d-aspartate receptors in rat hippocampus. J. Neurochem. 93 (2005) 1561-1567
21. 2 activity by calcium/calmodulin-dependent kinase II, c-AMP-dependent protein kinase, and casein kinase II. Proc. Natl. Acad. Sci. U.S.A. 88 (1991) 6770-6774
22. Quinn C.C., Gray G.E., and Hockfield S. A family of proteins implicated in axon guidance and outgrowth. J. Neurobiol. 41 (1999) 158-164
23. Rosslenbroich V., Lingsong D., Baader S.L., Noegel A., Gieselmann V., and Kappler J. Collapsin response mediator protein-4 regulates F-actin bundling. Exp. Cell. Res. 310 (2005) 434-444 T
24. Saito R., Onuki Y., Fujita G., Kusakawa K., Ishiguro J.A., Bibb T., Kishimoto S., and Hisanaga. Developmental regulation of the proteolysis of the p35 cyclin-dependent kinase 5 activator by phosphorylation. J. Neurosci. 23 (2003) 1189-1197
25. Salamino F., Averna M., Tedesco I., De Tullio R., Melloni E., and Pontremoli S. Modulation of rat brain calpastatin efficiency by post-translational modifications. FEBS Lett. 412 (1997) 433-438
26. Shiraha H., Glading A., Chou J., Jia Z., and Wells A. Activation of m-calpain (calpain II) by epidermal growth factor is limited by protein kinase A phosphorylation of m-calpain. Mol. Cell. Biol. 22 (2002) 2716-2727
27. Siman R., and Noszek J.C. Excitatory amino acids activate calpain I and induce structural protein breakdown in vivo. Neuron 1 (1988) 279-287
28. 2. J. Neurosci. 15 (1995) 3307-3317
29. 2 in the central nervous system: implication for neurodegenerative diseases. J. Lipid Res. 45 (2004) 205-213
30. Vartiainen N., Huang C.Y., Salminen A., Goldsteins G., Chan P.H., and Koistinaho J. Piroxicam and NS-398 rescue neurones from hypoxia/reoxygenation damage by a mechanism independent of cyclo-oxygenase inhibition. J. Neurochem. 76 (2001) 480-489
31. Vinade L., Petersen J.D., Do K., Dosemeci A., and Reese T.S. Activation of calpain may alter the postsynaptic density structure and modulate anchoring of NMDA receptors. Synapse 40 (2001) 302-309
32. Yagami T., Ueda K., Hata S., Kuroda T., Itoh N., Sakaguchi G., Okamura N., Sakaeda T., and Fujimoto M. S-2474, a novel nonsteroidal anti-inflammatory drug, rescues cortical neurons from human group IIA secretory phospholipase A(2)-induced apoptosis. Neuropharmacology 49 (2005) 174-184