Secreted phospholipase A2 potentiates glutamate-induced calcium increase and cell death in primary neuronal cultures

Journal of Neuroscience Research

Volumn 67, Issue 5, 2002, Pages 634-645

  Decoster, Mark A ^a   Lambeau, Gerard ^b   Lazdunski, Michel ^a   Bazan, Nicolas G ^a  

^a LOUISIANA STATE UNIVERSITY HEALTH SCIENCES CENTER   (United States)

^b INSTITUT DE PHARMACOLOGIE MOLÉCULAIRE ET CELLULAIRE   (France)

Author keywords

Calcium imaging; Cell death; Confocal microscopy; Cortical neurons; Glutamate; Hippocampal neurons; Secreted phospholipase A2

Indexed keywords

2,4 PYRROLIDINEDICARBOXYLIC ACID; ARACHIDONIC ACID; CALCIUM CHANNEL BLOCKING AGENT; COBALT; DIZOCILPINE; GLUTAMIC ACID; LACTATE DEHYDROGENASE; N METHYL DEXTRO ASPARTIC ACID RECEPTOR; N METHYL DEXTRO ASPARTIC ACID RECEPTOR BLOCKING AGENT; PHOSPHOLIPASE A2; AMINO ACID RECEPTOR BLOCKING AGENT; ANTIMUTAGENIC AGENT; CALCIUM; CALCIUM CHANNEL; COBALT CHLORIDE; DICARBOXYLIC ACID; NEUROTRANSMITTER UPTAKE INHIBITOR; PHOSPHOLIPASE A; PYRROLIDINE DERIVATIVE; PYRROLIDINE-2,4-DICARBOXYLIC ACID;

ANIMAL CELL; ARTICLE; CALCIUM CELL LEVEL; CELL DEATH; CELL SURVIVAL; CONTROLLED STUDY; ENZYME ACTIVITY; ENZYME RELEASE; NERVE CELL; NERVE FUNCTION; NEUROTRANSMITTER RELEASE; NONHUMAN; PRIORITY JOURNAL; RAT; ANIMAL; BRAIN CORTEX; CALCIUM SIGNALING; CELL CULTURE; DOSE RESPONSE; DRUG EFFECT; ENZYMOLOGY; HIPPOCAMPUS; INTRACELLULAR FLUID; METABOLISM; PHYSIOLOGY; SECRETION; SIGNAL TRANSDUCTION;

ANIMALS; ANTIMUTAGENIC AGENTS; ARACHIDONIC ACID; CALCIUM; CALCIUM CHANNELS; CALCIUM SIGNALING; CELL DEATH; CELLS, CULTURED; CEREBRAL CORTEX; COBALT; DICARBOXYLIC ACIDS; DOSE-RESPONSE RELATIONSHIP, DRUG; EXCITATORY AMINO ACID ANTAGONISTS; GLUTAMIC ACID; HIPPOCAMPUS; INTRACELLULAR FLUID; NEURONS; NEUROTRANSMITTER UPTAKE INHIBITORS; PHOSPHOLIPASES A; PYRROLIDINES; RATS; RECEPTORS, N-METHYL-D-ASPARTATE; SIGNAL TRANSDUCTION;

EID: 0036489223     PISSN: 03604012     EISSN: None     Source Type: Journal    
DOI: 10.1002/jnr.10131     Document Type: Article

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