Proteinase Inhibitors: Secretory Leukoprotease Inhibitor and Elafin

Encyclopedia of Respiratory Medicine, Four-Volume Set

Volumn , Issue , 2006, Pages 517-522

  Tetley, T D ^a  

^a IMPERIAL COLLEGE LONDON   (United Kingdom)

Author keywords

Acute lung injury; Adult respiratory distress syndrome; Antiproteinase; Chronic obstructive pulmonary disease; Clara cell; Elafin; Epithelial type II cell; Epithelium; Goblet cell; Immune defense; Inflammation; Lipopolysaccharide; Macrophage; Neutrophil; Neutrophil elastase; Pneumonia; Pre elafin; Secretory leukoprotease inhibitor; Trappin 2; Whey acidic protein; Wound healing

Indexed keywords

EID: 38049115511     PISSN: None     EISSN: None     Source Type: Book    
DOI: 10.1016/B0-12-370879-6/00330-6     Document Type: Chapter

References (13)

1. Aarbiou J., van Schadewijk A., Stolk J., et al. Human neutrophil defensins and secretory leukocyte proteinase inhibitor in squamous metaplastic epithelium of bronchial airways. Inflammation Research 2004, 53:230-238.
2. Ashcroft G.S., Lei K., Jin W., Longenecker G., et al. Secretory leukocyte protease inhibitor mediates non-redundant functions necessary for normal wound healing. Nature Medicine 2000, 6:1147-1153.
3. Chughtai B., O'Riordan T.G. Potential role of inhibitors of neutrophil elastase in treating diseases of the airway. Journal of Aerosol Medicine 2004, 17:289-298.
4. Clauss A., Lilja H., Lundwall A. A locus on human chromosome 20 contains several genes expressing protease inhibitor domains with homology to whey acidic protein. Biochemical Journal 2002, 368:233-242.
5. Doumas S., Kolokotronis A., Stefanopoulos P. Anti-inflammatory and antimicrobial roles of secretory leukocyte protease inhibitor. Infection and Immunity 2005, 73:1271-1274.
6. Greene C., Taggart C., Lowe G., et al. Local impairment of anti-neutrophil elastase capacity in community-acquired pneumonia. Journal of Infectious Diseases 2003, 188:769-776.
7. Henriksen P.A., Hitt M., Xing Z., et al. Adenoviral gene delivery of elafin and secretory leukocyte protease inhibitor attenuates NF-kappa B-dependent inflammatory responses of human endothelial cells and macrophages to atherogenic stimuli. Journal of Immunology 2004, 172:4535-4544.
8. Hiemstra P.S. Novel roles of protease inhibitors in infection and inflammation. Biochemical Society Transactions 2002, 30:116-120.
9. McMicheal J.W., Roghanian A., Jiang L., Ramage R., Sallenave J.M. The antimicrobial antiproteinase elafin binds to lipolysaccharide and modulates macrophage responses. American Journal of Respiratory Cell and Molecular Biology 2005, 32:443-452.
10. Molhuizen H.O.F., Alkemade H.A.C., Zeeuwen P.L.J.M., et al. SKALP/elafin. an elastase inhibitor from cultured human keratinocytes: purification, cDNA sequence, and evidence for transglutaminase cross-linking. Journal of Biological Chemistry 1993, 268:12028-12032.
11. Sallenave J.M. Antimicrobial activity of antiproteinases. Biochemical Society Transactions 2002, 30:111-115.
12. Schalkwijk J., Wiedow O., Hirose X.Y. The trappin gene family. proteins defined by an N-terminal transglutaminase substrate domain and a C-terminal four-disulphide core. Biochemical Journal 1999, 340:569-577.
13. Taggart C.C., Greene C.M., McElvaney N.G., O'Neill S. Secretory leucoprotease inhibitor prevents lipopolysaccharide-induced IkappaBalpha degradation without affecting phosphorylation or ubiquitination. Journal of Biological Chemistry 2002, 277:33648-33653.