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Volumn 2, Issue 4, 2007, Pages 403-408

Clinical use of exhaled biomarkers in COPD

Author keywords

COPD; EBC; ENO; Exhaled breath condensate; Nitric oxide

Indexed keywords

8 ISOPROSTANE; ALDEHYDE; BIOLOGICAL MARKER; COLLAGEN; CORTICOSTEROID; ELASTIN; HYDROGEN PEROXIDE; INTERLEUKIN 6; ISOPROSTANE DERIVATIVE; MATRIX METALLOPROTEINASE; MONOCYTE CHEMOTACTIC PROTEIN 1; NITRIC OXIDE; NITRIC OXIDE SYNTHASE; OXYGEN; PROLYLGLYCYLPROLINE; TRIPEPTIDE DERIVATIVE; UNCLASSIFIED DRUG;

EID: 38049105959     PISSN: 11769106     EISSN: None     Source Type: Journal    
DOI: None     Document Type: Review
Times cited : (14)

References (57)
  • 1
    • 0032884546 scopus 로고    scopus 로고
    • Serial measurements of exhaled nitric oxide during exacerbations of chronic obstructive pulmonary disease
    • Agusti AG et al. 1999, Serial measurements of exhaled nitric oxide during exacerbations of chronic obstructive pulmonary disease. Eur Respir J, 14:523-8.
    • (1999) Eur Respir J , vol.14 , pp. 523-528
    • Agusti, A.G.1
  • 2
    • 0033429105 scopus 로고    scopus 로고
    • Recommendations for standardized procedures for the on-line and off-line measurement of exhaled lower respiratory nitric oxide and nasal nitric oxide in adults and children - 1999. This official statement of the American Thoracic Society was adopted by the ATS Board of Directors, July 1999
    • American Thoracic Society
    • [ATS] American Thoracic Society. 1999. Recommendations for standardized procedures for the on-line and off-line measurement of exhaled lower respiratory nitric oxide and nasal nitric oxide in adults and children - 1999. This official statement of the American Thoracic Society was adopted by the ATS Board of Directors, July 1999. Am J Respir Crit Care Med, 160:2104-17.
    • (1999) Am J Respir Crit Care Med , vol.160 , pp. 2104-2117
  • 3
    • 33745445884 scopus 로고    scopus 로고
    • Pulmonary biomarkers in chronic obstructive pulmonary disease
    • Barnes PJ et al. 2006. Pulmonary biomarkers in chronic obstructive pulmonary disease. Am J Respir Cril Care Med, 174:6-14.
    • (2006) Am J Respir Cril Care Med , vol.174 , pp. 6-14
    • Barnes, P.J.1
  • 4
    • 0345073628 scopus 로고    scopus 로고
    • Increased leukotriene B4 and 8-isoprostane in exhaled breath condensate of patients with exacerbations of COPD
    • Biernacki WA, Kharitonov SA, Barnes PJ. 2003. Increased leukotriene B4 and 8-isoprostane in exhaled breath condensate of patients with exacerbations of COPD. Thorax, 58:294-8.
    • (2003) Thorax , vol.58 , pp. 294-298
    • Biernacki, W.A.1    Kharitonov, S.A.2    Barnes, P.J.3
  • 5
    • 0346901131 scopus 로고    scopus 로고
    • High levels of interleukin-6 in the exhaled breath condensate of patients with COPD
    • Bucchioni E et al. 2003. High levels of interleukin-6 in the exhaled breath condensate of patients with COPD. Respir Med, 97:1299-302.
    • (2003) Respir Med , vol.97 , pp. 1299-1302
    • Bucchioni, E.1
  • 6
    • 0041853629 scopus 로고    scopus 로고
    • Bronchodilator reversibility testing in chronic obstructive pulmonary disease
    • Calverley PM et al. 2003. Bronchodilator reversibility testing in chronic obstructive pulmonary disease. Thorax, 58:659-64.
    • (2003) Thorax , vol.58 , pp. 659-664
    • Calverley, P.M.1
  • 7
    • 0030976501 scopus 로고    scopus 로고
    • Corticosteroid reversibility in COPD is related to features of asthma
    • Chanez P et al. 1997. Corticosteroid reversibility in COPD is related to features of asthma. Am J Respir Crit Care Med, 155:1529-34.
    • (1997) Am J Respir Crit Care Med , vol.155 , pp. 1529-1534
    • Chanez, P.1
  • 8
    • 0031722239 scopus 로고    scopus 로고
    • Endogenous nitric oxide in patients with stable COPD: Correlates with severity of disease
    • Clini E et al. 1998. Endogenous nitric oxide in patients with stable COPD: correlates with severity of disease. Thorax, 53:881-3.
    • (1998) Thorax , vol.53 , pp. 881-883
    • Clini, E.1
  • 9
    • 0033841145 scopus 로고    scopus 로고
    • Production of endogenous nitric oxide in chronic obstructive pulmonary disease and patients with cor pulmonale. Correlates with echo-Doppler assessment
    • Clini E et al. 2000. Production of endogenous nitric oxide in chronic obstructive pulmonary disease and patients with cor pulmonale. Correlates with echo-Doppler assessment. Am J Respir Crit Care Med, 162:446-50.
    • (2000) Am J Respir Crit Care Med , vol.162 , pp. 446-450
    • Clini, E.1
  • 10
    • 0033036760 scopus 로고    scopus 로고
    • Increased exhaled nitric oxide in patients with stable chronic obstructive pulmonary disease
    • Corradi M et al. 1999. Increased exhaled nitric oxide in patients with stable chronic obstructive pulmonary disease. Thorax, 54:572-5.
    • (1999) Thorax , vol.54 , pp. 572-575
    • Corradi, M.1
  • 11
    • 0037614742 scopus 로고    scopus 로고
    • Aldehydes in exhaled breath condensate of patients with chronic obstructive pulmonary disease
    • Corradi M et al. 2003. Aldehydes in exhaled breath condensate of patients with chronic obstructive pulmonary disease. Am J Respir Crit Care Med, 167:1380-6.
    • (2003) Am J Respir Crit Care Med , vol.167 , pp. 1380-1386
    • Corradi, M.1
  • 12
    • 33747127127 scopus 로고    scopus 로고
    • Long-term oxygen treatment in chronic obstructive pulmonary disease: Recommendations for future research: an NHLBI workshop report
    • Croxton TL, Bailey WC. 2006. Long-term oxygen treatment in chronic obstructive pulmonary disease: recommendations for future research: an NHLBI workshop report. Am J Respir Crit Care Med, 174:373-8.
    • (2006) Am J Respir Crit Care Med , vol.174 , pp. 373-378
    • Croxton, T.L.1    Bailey, W.C.2
  • 13
    • 0037086026 scopus 로고    scopus 로고
    • Future research directions in chronic obstructive pulmonary disease
    • Croxton TL et al. 2002. Future research directions in chronic obstructive pulmonary disease. Am J Respir Crit Care Med, 165:838-44.
    • (2002) Am J Respir Crit Care Med , vol.165 , pp. 838-844
    • Croxton, T.L.1
  • 14
    • 0033884309 scopus 로고    scopus 로고
    • Validation of a new technique to assess exhaled hydrogen peroxide: Results from normals and COPD patients
    • De Benedetto BF et al. 2000. Validation of a new technique to assess exhaled hydrogen peroxide: results from normals and COPD patients. Monaldi Arch Chest Dis, 55:185-8.
    • (2000) Monaldi Arch Chest Dis , vol.55 , pp. 185-188
    • De Benedetto, B.F.1
  • 15
    • 10644250916 scopus 로고    scopus 로고
    • Long-term oral n-acetylcysteine reduces exhaled hydrogen peroxide in stable COPD
    • De Benedetto BF et al. 2005. Long-term oral n-acetylcysteine reduces exhaled hydrogen peroxide in stable COPD. Pulm Pharmacol Ther, 18;A1-7.
    • (2005) Pulm Pharmacol Ther , vol.18
    • De Benedetto, B.F.1
  • 16
    • 0029816451 scopus 로고    scopus 로고
    • Increased exhalation of hydrogen peroxide in patients with stable and unstable chronic obstructive pulmonary disease
    • Dekhuijzen PN et al. 1996. Increased exhalation of hydrogen peroxide in patients with stable and unstable chronic obstructive pulmonary disease. Am J Respir Crit Care Med, 154:813-16.
    • (1996) Am J Respir Crit Care Med , vol.154 , pp. 813-816
    • Dekhuijzen, P.N.1
  • 17
    • 0347362532 scopus 로고    scopus 로고
    • A simple method for estimating respiratory solute dilution in exhaled breath condensates
    • Effros RM et al. 2003. A simple method for estimating respiratory solute dilution in exhaled breath condensates. Am J Respir Crit Care Med, 168:1500-5.
    • (2003) Am J Respir Crit Care Med , vol.168 , pp. 1500-1505
    • Effros, R.M.1
  • 18
    • 0036499722 scopus 로고    scopus 로고
    • Dilution of respiratory solutes in exhaled condensates
    • Effros RM et al. 2002. Dilution of respiratory solutes in exhaled condensates. Am J Respir Crit Care Med, 165:663-9.
    • (2002) Am J Respir Crit Care Med , vol.165 , pp. 663-669
    • Effros, R.M.1
  • 19
    • 0037320195 scopus 로고    scopus 로고
    • Differences in airway inflammation in patients with fixed airflow obstruction due to asthma or chronic obstructive pulmonary disease
    • Fabbri LM et al. 2003. Differences in airway inflammation in patients with fixed airflow obstruction due to asthma or chronic obstructive pulmonary disease. Am J Respir Crit Care Med, 167:418-24.
    • (2003) Am J Respir Crit Care Med , vol.167 , pp. 418-424
    • Fabbri, L.M.1
  • 20
    • 0035883497 scopus 로고    scopus 로고
    • Exhaled nitric oxide and hydrogen peroxide in patients with chronic obstructive pulmonary disease: Effects of inhaled beclomethasone
    • Ferreira IM et al. 2001. Exhaled nitric oxide and hydrogen peroxide in patients with chronic obstructive pulmonary disease: effects of inhaled beclomethasone. Am J Respir Crit Care Med, 164:1012-15.
    • (2001) Am J Respir Crit Care Med , vol.164 , pp. 1012-1015
    • Ferreira, I.M.1
  • 21
    • 0028053211 scopus 로고
    • The biology of nitrogen oxides in the airways
    • Gaston B et al. 1994. The biology of nitrogen oxides in the airways. Am J Respir Crit Care Med, 149:538-51.
    • (1994) Am J Respir Crit Care Med , vol.149 , pp. 538-551
    • Gaston, B.1
  • 22
    • 0028007172 scopus 로고
    • Quantitation of nitrotyrosine levels in lung sections of patients and animals with acute lung injury
    • Haddad IY et al. 1994. Quantitation of nitrotyrosine levels in lung sections of patients and animals with acute lung injury. J Clin Invest, 94:2407-13.
    • (1994) J Clin Invest , vol.94 , pp. 2407-2413
    • Haddad, I.Y.1
  • 23
    • 0030823772 scopus 로고    scopus 로고
    • Requirement for macrophage elastase for cigarette smoke-induced emphysema in mice
    • Hautamaki RD et al. 1997. Requirement for macrophage elastase for cigarette smoke-induced emphysema in mice. Science, 277:2002-4.
    • (1997) Science , vol.277 , pp. 2002-2004
    • Hautamaki, R.D.1
  • 24
    • 0036084346 scopus 로고    scopus 로고
    • Killing of Klebsiella pneumoniae by human alveolar macrophages
    • Hickman-Davis JM et al. 2002. Killing of Klebsiella pneumoniae by human alveolar macrophages. Am J Physiol Lung Cell Mol Physiol, 282:L944-56.
    • (2002) Am J Physiol Lung Cell Mol Physiol , vol.282
    • Hickman-Davis, J.M.1
  • 25
    • 24644515785 scopus 로고    scopus 로고
    • Exhaled breath condensate: Methodological recommendations and unresolved questions
    • Horvath I et al. 2005. Exhaled breath condensate: methodological recommendations and unresolved questions. Eur Respir J, 26:523-48.
    • (2005) Eur Respir J , vol.26 , pp. 523-548
    • Horvath, I.1
  • 26
    • 0034990522 scopus 로고    scopus 로고
    • Isoprostanes: An overview and putative roles in pulmonary pathophysiology
    • Janssen LJ, 2001. Isoprostanes: an overview and putative roles in pulmonary pathophysiology. Am J Physiol Lung Cell Mol Physiol, 280: L1067-82.
    • (2001) Am J Physiol Lung Cell Mol Physiol , vol.280
    • Janssen, L.J.1
  • 27
    • 0027499150 scopus 로고
    • Airway and vascular effects of 8-epi-prostaglandin F2 alpha in isolated perfused rat lung
    • Kang KH et al. 1993. Airway and vascular effects of 8-epi-prostaglandin F2 alpha in isolated perfused rat lung. J Appl Physiol, 74:460-5.
    • (1993) J Appl Physiol , vol.74 , pp. 460-465
    • Kang, K.H.1
  • 28
    • 0034942666 scopus 로고    scopus 로고
    • Long-term administration of N-acetylcysteine decreases hydrogen peroxide exhalation in subjects with chronic obstructive pulmonary disease
    • Kasielski M, Nowak D. 2001. Long-term administration of N-acetylcysteine decreases hydrogen peroxide exhalation in subjects with chronic obstructive pulmonary disease. Respir Med, 95:448-56.
    • (2001) Respir Med , vol.95 , pp. 448-456
    • Kasielski, M.1    Nowak, D.2
  • 29
    • 0029664977 scopus 로고    scopus 로고
    • 8-Epi-PGF2 alpha, a novel noncyclooxygenase-derived prostaglandin, constricts airways in vitro
    • Kawikova I et al. 1996. 8-Epi-PGF2 alpha, a novel noncyclooxygenase-derived prostaglandin, constricts airways in vitro. Am J Respir Crit Care Med, 153:590-6.
    • (1996) Am J Respir Crit Care Med , vol.153 , pp. 590-596
    • Kawikova, I.1
  • 30
    • 0029145012 scopus 로고
    • Acute and chronic effects of cigarette smoking on exhaled nitric oxide
    • Kharitonov SA et al. 1995. Acute and chronic effects of cigarette smoking on exhaled nitric oxide. Am J Respir Crit Care Med, 152:609-12.
    • (1995) Am J Respir Crit Care Med , vol.152 , pp. 609-612
    • Kharitonov, S.A.1
  • 31
    • 33344465343 scopus 로고    scopus 로고
    • Ko FW et al. 2006. Exhaled breath condensate levels of 8-isoprostane, growth related oncogene alpha and monocyte chemoattractant protein-1 in patients with chronic obstructive pulmonary disease. Respir Med, 100:630-8.
    • Ko FW et al. 2006. Exhaled breath condensate levels of 8-isoprostane, growth related oncogene alpha and monocyte chemoattractant protein-1 in patients with chronic obstructive pulmonary disease. Respir Med, 100:630-8.
  • 32
    • 0037092556 scopus 로고    scopus 로고
    • pH in expired breath condensate of patients with inflammatory airway diseases
    • Kostikas K et al. 2002. pH in expired breath condensate of patients with inflammatory airway diseases. Am J Respir Crit Care Med, 165:1364-70.
    • (2002) Am J Respir Crit Care Med , vol.165 , pp. 1364-1370
    • Kostikas, K.1
  • 33
    • 0142010546 scopus 로고    scopus 로고
    • Oxidative stress in expired breath condensate of patients with COPD
    • Kostikas K et al. 2003. Oxidative stress in expired breath condensate of patients with COPD. Chest, 124:1373-80.
    • (2003) Chest , vol.124 , pp. 1373-1380
    • Kostikas, K.1
  • 34
    • 0031898729 scopus 로고    scopus 로고
    • Exhaled nitric oxide in chronic obstructive pulmonary disease
    • Maziak W et al. 1998. Exhaled nitric oxide in chronic obstructive pulmonary disease. Am J Respir Crit Care Med, 157:998-1002.
    • (1998) Am J Respir Crit Care Med , vol.157 , pp. 998-1002
    • Maziak, W.1
  • 35
    • 0025883342 scopus 로고
    • Nitric oxide: Physiology, pathophysiology, and pharmacology
    • Moncada S, Palmer RM, Higgs EA. 1991. Nitric oxide: physiology, pathophysiology, and pharmacology. Pharmacol Rev, 43:109-42.
    • (1991) Pharmacol Rev , vol.43 , pp. 109-142
    • Moncada, S.1    Palmer, R.M.2    Higgs, E.A.3
  • 36
    • 20344387191 scopus 로고    scopus 로고
    • Exhaled breath condensate analysis in patients with COPD
    • Montuschi P. 2005, Exhaled breath condensate analysis in patients with COPD. Clin Chim Acta, 356:22-34.
    • (2005) Clin Chim Acta , vol.356 , pp. 22-34
    • Montuschi, P.1
  • 37
    • 0033833221 scopus 로고    scopus 로고
    • Exhaled 8-isoprostane as an in vivo biomarker of lung oxidative stress in patients with COPD and healthy smokers
    • Montuschi P et al. 2000. Exhaled 8-isoprostane as an in vivo biomarker of lung oxidative stress in patients with COPD and healthy smokers. Am J Respir Crit Care Med, 162:1175-7.
    • (2000) Am J Respir Crit Care Med , vol.162 , pp. 1175-1177
    • Montuschi, P.1
  • 38
    • 0034827652 scopus 로고    scopus 로고
    • Exhaled carbon monoxide and nitric oxide in COPD
    • Montuschi P, Kharitonov SA, Barnes PJ. 2001. Exhaled carbon monoxide and nitric oxide in COPD. Chest, 120:496-501.
    • (2001) Chest , vol.120 , pp. 496-501
    • Montuschi, P.1    Kharitonov, S.A.2    Barnes, P.J.3
  • 39
    • 0030963753 scopus 로고    scopus 로고
    • The isoprostanes: Unique bioactive products of lipid peroxidation
    • Morrow JD, Roberts LJ. 1997. The isoprostanes: unique bioactive products of lipid peroxidation. Prog Lipid Res, 36:1-21.
    • (1997) Prog Lipid Res , vol.36 , pp. 1-21
    • Morrow, J.D.1    Roberts, L.J.2
  • 40
    • 0037115255 scopus 로고    scopus 로고
    • The isoprostanes: Their role as an index of oxidant stress status in human pulmonary disease
    • Morrow JD, Roberts LJ. 2002. The isoprostanes: their role as an index of oxidant stress status in human pulmonary disease. Am J Respir Crit Care Med, 166: S25-30.
    • (2002) Am J Respir Crit Care Med , vol.166
    • Morrow, J.D.1    Roberts, L.J.2
  • 42
    • 38049184820 scopus 로고    scopus 로고
    • Update on Selected Topics 2002. 02-5074. 2003. Bethesda, MD: National Institutes of Health.
    • Update on Selected Topics 2002. 02-5074. 2003. Bethesda, MD: National Institutes of Health.
  • 43
    • 34548729164 scopus 로고    scopus 로고
    • Global Initiative for Chronic Obstructive Lung Disease
    • National Heart, Lung and Blood Institute and World Health Organization, Bethesda, MD: National Heart, Lung and Blood Institute
    • [NHLBI] National Heart, Lung and Blood Institute and World Health Organization. 2005. Global Initiative for Chronic Obstructive Lung Disease. Global strategy for the diagnosis, management and prevention of chronic obstructive pulmonary disease. Updated 2003. Bethesda, MD: National Heart, Lung and Blood Institute.
    • (2005) Global strategy for the diagnosis, management and prevention of chronic obstructive pulmonary disease. Updated 2003
  • 44
    • 0035862148 scopus 로고    scopus 로고
    • 2 and thiobarbituric acid reactive substances (TBARs) by healthy subjects
    • 2 and thiobarbituric acid reactive substances (TBARs) by healthy subjects. Free Radic Biol Med, 30:178-86.
    • (2001) Free Radic Biol Med , vol.30 , pp. 178-186
    • Nowak, D.1
  • 45
    • 0033064218 scopus 로고    scopus 로고
    • Increased content of thiobarbituric acid-reactive substances and hydrogen peroxide in the expired breath condensate of patients with stable chronic obstructive pulmonary disease: No significant effect of cigarette smoking
    • Nowak D et al. 1999. Increased content of thiobarbituric acid-reactive substances and hydrogen peroxide in the expired breath condensate of patients with stable chronic obstructive pulmonary disease: no significant effect of cigarette smoking. Respir Med, 93:389-96.
    • (1999) Respir Med , vol.93 , pp. 389-396
    • Nowak, D.1
  • 46
    • 38049156186 scopus 로고    scopus 로고
    • Detection of proinflammatory peptides in exhaled breath condensate of COPD patients and healthy controls [abstract]
    • O'Reilly PJ et al. 2006. Detection of proinflammatory peptides in exhaled breath condensate of COPD patients and healthy controls [abstract]. Proc Am Thorac Soc, 3:AI 27.
    • (2006) Proc Am Thorac Soc , vol.3 , Issue.AI , pp. 27
    • O'Reilly, P.J.1
  • 47
    • 0033711405 scopus 로고    scopus 로고
    • Partial reversibility of airflow limitation and increased exhaled NO and sputum eosinophilia in chronic obstructive pulmonary disease
    • Papi A et al. 2000. Partial reversibility of airflow limitation and increased exhaled NO and sputum eosinophilia in chronic obstructive pulmonary disease. Am J Respir Crit Care Med, 162:1773-7.
    • (2000) Am J Respir Crit Care Med , vol.162 , pp. 1773-1777
    • Papi, A.1
  • 48
    • 0037102347 scopus 로고    scopus 로고
    • 4-Hydroxy-2-nonenal, a specific lipid peroxidation product, is elevated in lungs of patients with chronic obstructive pulmonary disease
    • Rahman I et al. 2002. 4-Hydroxy-2-nonenal, a specific lipid peroxidation product, is elevated in lungs of patients with chronic obstructive pulmonary disease. Am J Respir Crit Care Med, 166:490-5.
    • (2002) Am J Respir Crit Care Med , vol.166 , pp. 490-495
    • Rahman, I.1
  • 49
    • 0030752487 scopus 로고    scopus 로고
    • Oxidative stress in chronic obstructive pulmonary disease. Oxidative Stress Study Group
    • Repine JE, Bast A, Lankhorst I. 1997. Oxidative stress in chronic obstructive pulmonary disease. Oxidative Stress Study Group. Am J Respir Crit Care Med, 156:341-57.
    • (1997) Am J Respir Crit Care Med , vol.156 , pp. 341-357
    • Repine, J.E.1    Bast, A.2    Lankhorst, I.3
  • 50
    • 0034652768 scopus 로고    scopus 로고
    • Measurement ofF(2)-isoprostanes as an index of oxidative stress in vivo
    • Roberts LJ, Morrow JD. 2000. Measurement ofF(2)-isoprostanes as an index of oxidative stress in vivo. Free Radic Biol Med, 28:505-13.
    • (2000) Free Radic Biol Med , vol.28 , pp. 505-513
    • Roberts, L.J.1    Morrow, J.D.2
  • 51
    • 0032988330 scopus 로고    scopus 로고
    • Markers of nitric oxide metabolism in sputum and exhaled air are not increased in chronic obstructive pulmonary disease
    • Rutgers SR et al. 1999. Markers of nitric oxide metabolism in sputum and exhaled air are not increased in chronic obstructive pulmonary disease. Thorax, 54:576-80.
    • (1999) Thorax , vol.54 , pp. 576-580
    • Rutgers, S.R.1
  • 52
    • 0344413022 scopus 로고    scopus 로고
    • Neutrophil elastase contributes to cigarette smoke-induced emphysema in mice
    • Shapiro SD et al. 2003. Neutrophil elastase contributes to cigarette smoke-induced emphysema in mice. Am J Pathol, 163:2329-35.
    • (2003) Am J Pathol , vol.163 , pp. 2329-2335
    • Shapiro, S.D.1
  • 53
    • 18244410118 scopus 로고    scopus 로고
    • The pathogenesis of chronic obstructive pulmonary disease: Advances in the past 100 years
    • Shapiro SD, Ingenito EP. 2005. The pathogenesis of chronic obstructive pulmonary disease: advances in the past 100 years. Am J Respir Cell Mol Biol, 32:367-72.
    • (2005) Am J Respir Cell Mol Biol , vol.32 , pp. 367-372
    • Shapiro, S.D.1    Ingenito, E.P.2
  • 54
    • 19444385389 scopus 로고    scopus 로고
    • Use of exhaled nitric oxide measurements to guide treatment in chronic asthma
    • Smith AD et al. 2005. Use of exhaled nitric oxide measurements to guide treatment in chronic asthma. N Engl J Med, 352:2163-73.
    • (2005) N Engl J Med , vol.352 , pp. 2163-2173
    • Smith, A.D.1
  • 55
    • 0028951568 scopus 로고
    • Elastin and collagen degradation products in urine of smokers with and without chronic obstructive pulmonary disease
    • Stone PJ et al. 1995. Elastin and collagen degradation products in urine of smokers with and without chronic obstructive pulmonary disease. Am J Respir Crit Care Med, 151:952-9.
    • (1995) Am J Respir Crit Care Med , vol.151 , pp. 952-959
    • Stone, P.J.1
  • 56
    • 0042072800 scopus 로고    scopus 로고
    • Effects of inhaled corticosteroids with different lung deposition on exhaled hydrogen peroxide in stable COPD patients
    • van Beurden WJ et al. 2003. Effects of inhaled corticosteroids with different lung deposition on exhaled hydrogen peroxide in stable COPD patients. Respiration, 70:242-8.
    • (2003) Respiration , vol.70 , pp. 242-248
    • van Beurden, W.J.1
  • 57
    • 33644828187 scopus 로고    scopus 로고
    • A novel peptide CXCR ligand derived from extracellular matrix degradation during airway inflammation
    • Weathington NM et al. 2006. A novel peptide CXCR ligand derived from extracellular matrix degradation during airway inflammation. Nat Med.
    • (2006) Nat Med
    • Weathington, N.M.1


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