Exhaled nitric oxide in chronic obstructive pulmonary disease

American Journal of Respiratory and Critical Care Medicine

Volumn 157, Issue 3 PART I, 1998, Pages 998-1002

  Maziak, Wasim ^a   Loukides, Stelios ^a   Culpitt, Sarah ^a   Sullivan, Paul ^a   Kharitonov, Sergei A ^a   Barnes, Peter J ^a  

^a NATIONAL HEART AND LUNG INSTITUTE   (United Kingdom)

Author keywords

[No Author keywords available]

Indexed keywords

NITRIC OXIDE;

ADULT; AGED; AIRWAY OBSTRUCTION; ARTICLE; CHRONIC BRONCHITIS; CHRONIC OBSTRUCTIVE LUNG DISEASE; DISEASE ACTIVITY; DISEASE SEVERITY; FEMALE; HUMAN; INFLAMMATION; LUNG FUNCTION TEST; MAJOR CLINICAL STUDY; MALE; PRIORITY JOURNAL;

ADMINISTRATION, INHALATION; ADMINISTRATION, TOPICAL; ANALYSIS OF VARIANCE; ANDROSTADIENES; ANTI-INFLAMMATORY AGENTS; BIOLOGICAL MARKERS; BRONCHITIS; CHRONIC DISEASE; FEMALE; FORCED EXPIRATORY VOLUME; GLUCOCORTICOIDS; HUMANS; LUNG; LUNG DISEASES, OBSTRUCTIVE; MALE; MIDDLE AGED; NITRIC OXIDE; REGRESSION ANALYSIS; RESPIRATION; SEVERITY OF ILLNESS INDEX; SMOKING; SMOKING CESSATION;

EID: 0031898729     PISSN: 1073449X     EISSN: None     Source Type: Journal    
DOI: 10.1164/ajrccm.157.3.97-05009     Document Type: Article

References (33)

1. American Thoracic Society. 1995. Standards for the diagnosis and care. of patients with chronic obstructive pulmonary disease. Am. J. Respir. Crit. Care Med. 152:78-83.
2. Sherrill, D. L., M. D. Lebowitz, and B. Burrows. 1990. Epidemiology of chronic obstructive pulmonary disease. Clin. Chest Med. 11:375-388.
3. Barnes, P. J., and S. A. Kharitonov. 1996. Exhaled nitric oxide: a new lung function test. Thorax 51:233-237.
4. Barnes, P. J. 1995. Nitric oxide and airway disease. Ann. Med. 27:91-97.
5. Nathan, C. F., and J. B. Hibbs. 1991. Role of nitric oxide synthesis in macrophage antimicrobial activity. Curr. Opinion Immunol. 3:65-70.
6. Robbins, R. A., P. J. Barnes, and D. L. Springall. 1994. Expression of inducible nitric oxide synthase in human bronchial epithelial cells. Biochem. Biophys. Res. Commun. 203:209-218.
7. Keating, V. M., P. D. Collins, D. M. Scott, and P. J. Barnes. 1996. Differences in interleukin-8 and tumor necrosis factor-α in induced sputum from patients with chronic obstructive pulmonary disease or asthma. Am. J. Respir. Crit. Care Med. 153:530-534.
8. American Thoracic Society. 1987. Standards for the diagnosis and care of patients with chronic obstructive pulmonary disease and asthma. Am. Rev. Respir. Dis. 134:225-243.
9. American Thoracic Society. 1991. Lung function testing: selection of reference values and interpretative strategies (statement). Am. Rev. Respir. Dis. 144:1201-1218.
10. Kharitonov, S. A., and P. J. Barnes. 1997. Nasal contribution to exhaled NO during exhalation against resistance or during breathholding. Thorax 52:540-544.
11. Hogman, M., S. Stromberg, U. Schodin, C. Frostell, G. Hedenstierna, and L. E. Gustafsson. 1997. Nitric oxide from the human respiratory tract effectively quantified by standardized single-breath measurements. Acta Physiol. Scand. 159:345-346.
12. Kharitonov, S. A., K. Alving, and P. J. Barnes. 1997. Exhaled and nasal nitric oxide measurements: recommendations. Eur. Respir. J. 10:1683-1693.
13. Kharitonov, S. A., K. F. Chung, D. Evans, B. J. O'Connor, and P. J. Barnes. 1996. Increased exhaled nitric oxide in asthma is mainly derived from the lower respiratory tract. Am. J. Respir. Crit. Care Med. 153:1773-1780.
14. Massaro, A. F., S. Mehta, C. M. Lilly, L. Kobzik, J. J. Reilly, and J. M. Drazen. 1996. Elevated nitric oxide concentrations in isolated lower airway gas of asthmatic subjects. Am. J. Respir. Crit Care Med. 153:1510-1514.
15. Rutgers, S. R., D. S. Postma, Thw. Van de Mark, and G. H. Koeter. 1996. Nitric oxide in exhaled air in COPD. Eur. Respir. J. 9(Suppl. 23):13S.
16. Prolin, G., T. Anden, and G. Hedenstierna. 1994. Nitric oxide in expired air and during exercise. Acta Physiol. Scand. 151:159-163.
17. Imada, M., J. Iwamoto, S. Nonaka, Y. Kobayashi, and T. Unno. 1996. Measurement of nitric oxide in human nasal airway. Eur. Respir. J. 9:556-559.
18. Schedin, U., C. Frostell, M. G. Persson, J. Jacobsson, G. Andersson, and L. E. Gustafsson. 1995. Contribution from upper and lower airways to exhaled endogenous nitric oxide in humans. Acta Anaesthesiol. Scand. 39:327-332.
19. Kharitonov, S. A., R. A. Robbins, D. Yates, V. Keating, and P. J. Barnes. 1995. Acute and chronic effects of cigarette smoking on exhaled nitric oxide. Am. J. Respir. Crit. Care Med. 152:609-612.
20. Persson, M. G., O. Zetterstrom, V. Argrenius, E. Ihre, and L. E. Gustafsson. 1994. Single-breath nitric oxide measurements in asthmatic patients and smokers. Lancet 343:146-147.
21. Rengasamy, A., and R. A. Johns. 1993. Regulation of nitric oxide synthase by nitric oxide. Mol. Pharmacol. 44:124-128.
22. Repine, J. E. 1996. Oxidant-antioxidant imbalances. In C. L. A. van Herwaarden, J. E. Repine, P. Vermiere, and C. van Well, editors. COPD: Diagnosis and Treatment. Excerpta Medica, Amsterdam. 40-44.
23. Jain, B., I. Lubenstein, R. A. Robbins, K. L. Leise, and J. H. Sisson. 1993. Modulation of airway epithelial cell ciliary beat frequency by nitric oxide. Biochem. Biophys. Res. Commun. 191:83-88.
24. Moncada, S., and A. Higgs. 1993. The L-arginin-nitric oxide pathway. N. Engl. J. Med. 329:2002-2012.
25. Belvisi, M. G., C. D. Stretton, M. Yacoub, and P. J. Barnes. 1992. Nitric oxide is the endogenous neutrotransmitter of bronchodilator nerves in humans. Eur. J. Pharmacol. 210:221-222.
26. Hogman, M., C. G. Frostell, H. Hedenstrom, and G. Hedenstierna. 1993. Inhalation of nitric oxide modulates adult human bronchial tone. Am. Rev. Respir. Dis. 148:1474-1478.
27. Roger, N., J. A. Barbera, R. Farre, A. Cobos, J. Roca, and R. Rodriguez-Roisin. 1996. Effect of nitric oxide inhalation on respiratory system resistance in chronic obstructive pulmonary disease. Eur. Respir. J. 9:190-195.
28. Giaid, A., and D. Saleh. 1995. Reduced expression of endothelial nitric oxide synthase in the lungs of patients with pulmonary hypertension. N. Engl. J. Med. 333:214-221.
29. Robbins, R. A., A. A. Floreani, S. G. Von Essen, J. H. Sisson, G. E. Hill, I. Rubenstein, and R. G. Townley. 1996. Measurement of exhaled nitric oxide by three different techniques. Am. J. Respir. Crit. Care Med. 153:1631-1635.
30. Dekhuijzen, P. N. R., K. K. H. Aben, I. Dekker, L. P. H. J. Aarts, P. L. M. L. Wielders, C. L. A. van Herwaarden, and A. Bast. 1996. Increased exhalation of hydrogen peroxide in patients with stable and unstable chronic obstructive pulmonary disease. Am. J. Respir. Crit. Care Med. 154:813-316.
31. Kanazawa, H., S. Shoji, K. Hirata, N. Kuribara, and J. Yoshikawa. 1996. Role of endogenous nitric oxide in airflow obstruction in smokers. Chest 110:927-929.
32. 1 in smokers are associated with increased levels of sputum neutrophils. Thorax 51:267-271.
33. Keatings, V. M., and P. J. Barnes. 1997. Granulocyte activation markers in induced sputum: comparison between chronic obstructive pulmonary disease, asthma and normal subjects. Am. J. Respir. Crit. Care Med. 155:449-453.