Replacement of dietary soy protein isolate with concentrates of soy 7S or 11S globulin has minimal or no effects on plasma lipoprotein profiles and biomarkers of coronary risk in monkeys

Atherosclerosis

Volumn 196, Issue 1, 2008, Pages 76-80

  Adams, Michael R ^a   Anthony, Mary S ^a   Chen, Haiying ^a   Clarkson, Thomas B ^a  

^a WAKE FOREST SCHOOL OF MEDICINE   (United States)

Author keywords

11S globulin; 7S globulin; Biomarkers; Lipoproteins; Monkeys; Soy

Indexed keywords

BIOLOGICAL MARKER; CASEIN; ENDOTHELIAL LEUKOCYTE ADHESION MOLECULE 1; GLOBULIN; GLOBULIN 11S; GLYCININ; HIGH DENSITY LIPOPROTEIN CHOLESTEROL; IMMUNOGLOBULIN 7S; ISOFLAVONE; LACTALBUMIN; LOW DENSITY LIPOPROTEIN CHOLESTEROL; MONOCYTE CHEMOTACTIC PROTEIN 1; PLASMINOGEN ACTIVATOR INHIBITOR 1; SOYBEAN PROTEIN; TRANSFORMING GROWTH FACTOR BETA1; TRIACYLGLYCEROL; UNCLASSIFIED DRUG; VASCULAR CELL ADHESION MOLECULE 1; VERY LOW DENSITY LIPOPROTEIN CHOLESTEROL;

ANIMAL EXPERIMENT; ANIMAL MODEL; ARTICLE; ATHEROSCLEROSIS; CHOLESTEROL BLOOD LEVEL; CONTROLLED STUDY; CORONARY RISK; DIETARY INTAKE; LIPOPROTEIN BLOOD LEVEL; MALE; MONKEY; NONHUMAN; PRIORITY JOURNAL;

ANIMALS; ATHEROSCLEROSIS; CHOLESTEROL; CROSS-OVER STUDIES; DIETARY SUPPLEMENTS; GLOBULINS; HYPERCHOLESTEROLEMIA; INFLAMMATION; MACACA FASCICULARIS; MALE; SOYBEAN PROTEINS;

EID: 38049082955     PISSN: 00219150     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.atherosclerosis.2007.01.037     Document Type: Article

References (29)

1. Basu A., Devaraj S., and Jialal I. Dietary factors that promote or retard inflammation. Arterioscler Thromb Vasc Biol 26 (2006) 995-1001
2. Adams M.R., Golden D.L., Franke A.A., Potter S.M., Smith H.S., and Anthony M.S. Dietary soy β-conglycinin (7S globulin) inhibits atherosclerosis in mice. J Nutr 134 (2004) 511-516
3. Lovati M.R., Manzoni C., Corsini A., et al. Low density lipoprotein receptor activity is modulated by soybean globulins in cell culture. J Nutr 122 (1992) 1971-1978
4. Lovati M.R., Manzoni C., Corsini A., Granata A., Fumagalli R., and Sirtori C.R. 7S globulin from soybean is metabolized in human cell cultures by a specific uptake and degradation system. J Nutr 126 (1996) 2831-2842
5. Sirtori C.R., Even R., and Lovati M.R. Soybean protein diet and plasma cholesterol: from therapy to molecular mechanisms. Ann NY Acad Sci 676 (1993) 188-201
6. Duranti M., Lovati M.R., Dani V., et al. The α' subunit from soybean 7S globulin lowers plasma lipids and upregulates liver β-VLDL receptors in rats fed a hypercholesterolemic diet. J Nutr 134 (2004) 1334-1339
7. Lovati M., Manzoni C., Gianazza E., et al. Soy protein peptides regulate cholesterol homeostasis in Hep G2 cells. J Nutr 130 (2000) 2543-2549
8. Gianazza E., Eberini I., Arnoldi A., Wait R., and Sirtori C.R. A proteomic investigation of isolated soy proteins with variable effects in experimental and clinical studies. J Nutr 133 (2003) 9-14
9. Moriyama T., Kishimoto K., Nagai K., et al. β-conglycinin diet suppresses serum triglyceride levels in normal and genetically obese mice by induction of β-oxidation, downregulation of fatty acid synthase and inhibition of triglyceride absorption. Biosci Biothechnol Biochem 68 (2004) 352-359
10. Aoyama T., Kohno M., Saito T., et al. Reduction by phytate-reduced β-conglycinin of plasma triglyceride level of young and adult rats. Biosci Biothechnol Biochem 65 (2001) 1071-1075
11. St Clair R.W., and Anthony M.S. Soy, isoflavones and atherosclerosis. Handb Exp Pharmacol 170 (2005) 301-323
12. Coward L., Smith M., Kirk M., and Barnes S. Chemical modification of isoflavones in soyfoods during cooking and processing. Am J Clin Nutr 68 (1998) 1486S-1491S
13. Allain C.C., Poon L.S., Chan C.S.G., Richmond W., and Fu P.C. Enzymatic determination of total serum cholesterol. Clin Chem 20 (1974) 470-475
14. NHLBI. Manual of laboratory operations: lipid research clinics program, vol. 1 (2004), NHLBI, NIH; DHEW publication NIH 75-268, Bethesda
15. Fossati P., and Principe L. Serum triglycerides determined colorimetrically with an enzyme that produces hydrogen peroxide. Clin Chem 28 (1982) 2077-2080
16. Baba T., Ueda A., Kohno M., et al. Effects of soybean β-conglycinin on body fat ratio and serum lipid levels in healthy volunteers of female university students. J Nutr Sci Vitaminol 50 (2004) 26-33
17. West S.G., Hilpert K.F., Juturu V., et al. Effects of including soy protein in a blood cholesterol-lowering diet on markers of cardiac risk in men and in postmenopausal women with and without hormone replacement therapy. J Womens Health 14 (2005) 253-262
18. Wagner J.D., Schwenke D.C., Greaves K.A., et al. Soy protein with isoflavones, but not an isoflavone-rich supplement, improves arterial low density lipoprotein metabolism and atherogenesis. Arterioscler Thromb Vasc Biol 23 (2003) 2241-2246
19. Blum A., Lang N., Peleg A., et al. Effects of oral soy protein on markers of inflammation in postmenopausal women with mild hypercholesterolemia. Am Heart J 145 (2003) e7
20. Hall W.L., Vafeiadou K., Hallund J., et al. Soy isoflavone-enriched foods and inflammatory biomarkers of cardiovascular disease risk in postmenopausal women: interactions with genotype and equol production. Am J Clin Nutr 82 (2005) 1260-1268
21. Steinberg F.M., Guthrie N.L., Villablanca A.C., Kumar K., and Murray M.J. Soy protein with isoflavones has favorable effects on endothelial function that are independent of lipid and antioxidant effects in healthy postmenopausal women. Am J Clin Nutr 78 (2003) 128-130
22. Register T.C., Cann J.A., Kaplan J.R., et al. Effects of soy isoflavones and conjugated equine estrogens on inflammatory markers in atherosclerotic, ovariectomized monkeys. J Clin Endocrinol Metab 90 (2005) 1734-1740
23. 1 concentrations and hemostatic risk factors for coronary heart disease in healthy subjects. Am J Clin Nutr 76 (2002) 373-377
24. Atkinson C., Oosthuizen W., Scollen S., Loktionov A., Day N.E., and Bingham S.A. Modest protective effects of isoflavones from a red clover-derived dietary supplement on cardiovascular disease risk factors in perimenopausal women, and evidence of an interaction with ApoE genotype in 49-65 year-old women. J Nutr 134 (2004) 1759-1764
25. Colacurci N., Chiantera A., Fornaro F., et al. Effects of soy isoflavones on endothelial function in healthy postmenopausal women. Menopause 12 (2005) 299-307
26. Masuda O., Nakamura Y., and Takano T. Antihypertensive peptides are present in aorta after oral administration of sour milk containing these peptides to spontaneously hypertensive rats. J Nutr 126 (1996) 3063-3068
27. Kitts D.D., and Weiler K. Bioactive proteins and peptides from food sources. Applications bioprocesses used in isolation and recovery. Curr Pharm Des 9 (2003) 1309-1323
28. Jacoby D.S., and Rader D.J. Renin-angiotensin system and atherothrombotic disease. From genes to treatment. Arch Intern Med 163 (2003) 1155-1164
29. Adams M.R., Golden D.L., Williams J.K., et al. Soy protein containing isoflavones reduces the size of atherosclerotic plaques without influencing coronary artery reactivity. J Nutr 135 (2005) 2852-2856