Immunohistochemical characterization of cardiac vagal preganglionic neurons in the rat

Autonomic Neuroscience: Basic and Clinical

Volumn 106, Issue 2, 2003, Pages 132-137

  Takanaga, Akinori ^a   Hayakawa, Tetsu ^a   Tanaka, Koichi ^a   Kawabata, Keigo ^a   Maeda, Seishi ^a   Seki, Makoto ^a  

^a HYOGO COLLEGE OF MEDICINE   (Japan)

Author keywords

Calcitonin gene related peptide; Choline acetyltransferase; Dorsal motor nucleus of the vagus; Heart; Nitric oxide synthase; Nucleus ambiguus; Retrograde tracing

Indexed keywords

CALCITONIN GENE RELATED PEPTIDE; CHOLERA TOXIN B SUBUNIT; CHOLINE ACETYLTRANSFERASE; NITRIC OXIDE SYNTHASE; TRACER; TYROSINE 3 MONOOXYGENASE;

ADRENERGIC NERVE; AMBIGUUS NUCLEUS; ANIMAL TISSUE; ARTICLE; CELL LABELING; CHOLINERGIC NERVE; CONTROLLED STUDY; GANGLION; HEART NERVE; IMMUNOHISTOCHEMISTRY; IMMUNOREACTIVITY; INJECTION; MALE; MOTONEURON NUCLEUS; NONHUMAN; PREGANGLIONIC NERVE; PRIORITY JOURNAL; RAT; SINUS NODE; VAGUS NERVE;

EID: 0038826479     PISSN: 15660702     EISSN: None     Source Type: Journal    
DOI: 10.1016/S1566-0702(03)00127-9     Document Type: Article

References (22)

1. Armstrong D.M., Saper C.B., Levey A.I., Wainer B.H., Terry R.D. Distribution of cholinergic neurons in rat brain: demonstrated by the immunocytochemical localization of choline acetyltransferase. J. Comp. Neurol. 216:1983;53-68.
2. Bieger D., Hopkins D.A. Viscerotopic representation of the upper alimentary tract in the medulla oblongata in the rat: the nucleus ambiguus. J. Comp. Neurol. 262:1987;546-562.
3. Blinder K.J., Gatti P.J., Johnson T.A., Lauenstein J.-M., Coleman W.P., Gray A.L., Massari V.J. Ultrastructural circuitry of cardiorespiratory reflexes: there is a monosynaptic path between the nucleus of the solitary tract and vagal preganglionic motoneurons controlling atrioventricular condition in the cat. Brain Res. 785:1998;143-157.
4. Cheng S.-B., Hayakawa T., Kuchiiwa S., Maeda S., Ito H., Seki M., Nakagawa S. Evidence for the collateral innervation of the esophagus and the heart from neurons in the compact formation of the nucleus ambiguus of the rat. Brain Res. 832:1999;171-174.
5. Cheng Z., Powley T.L., Schwaber J.S., Doyle F.J. III Projections of the dorsal motor nucleus of the vagus to cardiac ganglia of rat atria: an anterograde tracing study. J. Comp. Neurol. 410:1999;320-341.
6. Conlon K., Kidd C. Neuronal nitric oxide facilitates vagal chronotropic and dromotropic actions on the heart. J. Auton. Nerv. Syst. 75:1999;136-146.
7. Izzo P.N., Deuchars J., Spyer K.M. Localization of cardiac vagal preganglionic motoneurons in the rat: immunocytochemical evidence of synaptic inputs containing 5-hydroxytryptamine. J. Comp. Neurol. 327:1993;572-583.
8. Kalia M., Fuxe K., Goldstein M. Rat medulla oblongata: II. Dopaminergic, noradrenergic (A1 and A2) and adrenergic neurons, nerve fibers, and presumptive terminal processes. J. Comp. Neurol. 233:1985;308-332.
9. Krowicki Z.K., Sharkey K.A., Serron S.C., Nathan N.A., Hornby P.J. Distribution of nitric oxide synthase in rat dorsal vagal complex and effects of microinjection of nitric oxide compounds upon gastric motor function. J. Comp. Neurol. 377:1997;49-69.
10. Lee B.H., Lynn R.B., Lee H.-S., Miselis R.R., Altschuler S.M. Calcitonin gene-related peptide in nucleus ambiguus motoneurons in rat: viscerotopic organization. J. Comp. Neurol. 320:1992;531-543.
11. Luppi P.-H., Fort P., Jouvet M. Iontophoretic application of unconjugated cholera toxin B subunit (CTb) combined with immunohistochemistry of neurochemical substances: a method for transmitter identification of retrogradely labeled neurons. Brain Res. 534:1990;209-224.
12. Massari V.J., Johnson T.A., Gatti P.J. Cardiotopic organization of the nucleus ambiguus? An anatomical and physiological analysis of neurons regulating atrioventricular conduction. Brain Res. 679:1995;227-240.
13. Massari V.J., Dickerson L.W., Gray A.L., Lauenstein J.-M., Blinder K.J., Newsome J.T., Rodak D.J., Fleming T.J., Gatti P.J., Gillis R.A. Neural control of left ventricular contractility in the dog heart: synaptic interactions of negative inotropic vagal preganglionic neurons in the nucleus ambiguus with tyrosine hydroxylase immunoreactive terminals. Brain Res. 802:1998;205-220.
14. Moore R.Y. Cranial motor neurons contain either galanin- or calcitonin gene-related peptidelike immunoreactivity. J. Comp. Neurol. 282:1989;512-522.
15. Panneton W.M., McCulloch P.F., Tan Y., Tan Y., Yavari P. Brainstem origin of preganglionic cardiac motoneurons in the muskrat. Brain Res. 738:1996;342-346.
16. Paxinos G., Watson C. The Rat Brain in Stereotaxic Coordinates. 1997;Academic Press, San Diego.
17. Ruggeri P., Battaglia A., Ermirio R., Grossini E., Molinari C., Mary D.A., Vacca G. Role of nitric oxide in the control of the heart rate within the nucleus ambiguus of rats. NeuroReport. 28:2000;481-485.
18. Ruggiero D.A., Giuliano R., Anwar M., Stornetta R., Reis D.J. Anatomical substrate of cholinergic-autonomic regulation in the rat. J. Comp. Neurol. 292:1990;1-53.
19. Standish A., Enquist L.W., Schwaber J.S. Innervation of the heart and its central medullary origin defined by viral tracing. Science. 263:1994;232-234.
20. Standish A., Enquist L.W., Escardo J.A., Schwaber J.S. Central neuronal circuit innervating the rat heart defined by transneuronal transport of pseudorabies virus. J. Neurosci. 15:1995;1998-2012.
21. Stuesse S.L. Origins of cardiac vagal preganglionic fibers: a retrograde transport study. Brain Res. 236:1982;15-25.
22. Takami K., Kawai Y., Shiosaka S., Lee Y., Girgis S., Hillyard C.J., Macintyre I., Emson P.C., Toyama M. Immunohistochemical evidence for the coexistence of calcitonin gene-related peptide- and choline acetyltransferase-like immunoreactivity in neurons of the rat hypoglossal, facial and ambiguus nuclei. Brain Res. 328:1985;386-389.