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Volumn 367, Issue 1, 2008, Pages 208-212

Tauroursodeoxycholic acid reduces bile acid-induced apoptosis by modulation of AP-1

Author keywords

AP 1; Apoptosis; cFos; Cholestasis; JunB; Liver; Signal transduction; Taurolithocholic acid; Tauroursodeoxycholic acid

Indexed keywords

BILE ACID; PROTEIN C FOS; TAUROLITHOLIC ACID; TAUROURSODEOXYCHOLIC ACID; TRANSCRIPTION FACTOR AP 1; TRANSCRIPTION FACTOR JUNB; UNCLASSIFIED DRUG; URSODEOXYCHOLIC ACID;

EID: 38049021096     PISSN: 0006291X     EISSN: 10902104     Source Type: Journal    
DOI: 10.1016/j.bbrc.2007.12.122     Document Type: Article
Times cited : (28)

References (36)
  • 1
    • 0036382432 scopus 로고    scopus 로고
    • Cholestatic liver disease: pathophysiology and therapeutic options
    • Hofmann A.F. Cholestatic liver disease: pathophysiology and therapeutic options. Liver 22 Suppl 2 (2002) 14-19
    • (2002) Liver , vol.22 , Issue.SUPPL. 2 , pp. 14-19
    • Hofmann, A.F.1
  • 2
    • 0031005366 scopus 로고    scopus 로고
    • Nuclear DNA fragmentation and expression of Bcl-2 in primary biliary cirrhosis
    • Koga H., Sakisaka S., Ohishi M., Sata M., and Tanikawa K. Nuclear DNA fragmentation and expression of Bcl-2 in primary biliary cirrhosis. Hepatology 25 (1997) 1077-1084
    • (1997) Hepatology , vol.25 , pp. 1077-1084
    • Koga, H.1    Sakisaka, S.2    Ohishi, M.3    Sata, M.4    Tanikawa, K.5
  • 3
    • 0034733547 scopus 로고    scopus 로고
    • The bile acid taurochenodeoxycholate activates a phosphatidylinositol 3-kinase-dependent survival signaling cascade
    • Rust C., Karnitz L.M., Paya C.V., Moscat J., Simari R.D., and Gores G.J. The bile acid taurochenodeoxycholate activates a phosphatidylinositol 3-kinase-dependent survival signaling cascade. J. Biol. Chem. 275 (2000) 20210-20216
    • (2000) J. Biol. Chem. , vol.275 , pp. 20210-20216
    • Rust, C.1    Karnitz, L.M.2    Paya, C.V.3    Moscat, J.4    Simari, R.D.5    Gores, G.J.6
  • 5
    • 0036241214 scopus 로고    scopus 로고
    • Taurolithocholic acid-3 sulfate induces CD95 trafficking and apoptosis in a c-Jun N-terminal kinase-dependent manner
    • Graf D., Kurz A.K., Fischer R., Reinehr R., and Haussinger D. Taurolithocholic acid-3 sulfate induces CD95 trafficking and apoptosis in a c-Jun N-terminal kinase-dependent manner. Gastroenterology 122 (2002) 1411-1427
    • (2002) Gastroenterology , vol.122 , pp. 1411-1427
    • Graf, D.1    Kurz, A.K.2    Fischer, R.3    Reinehr, R.4    Haussinger, D.5
  • 6
    • 0031950282 scopus 로고    scopus 로고
    • Ursodeoxycholic acid may inhibit deoxycholic acid-induced apoptosis by modulating mitochondrial transmembrane potential and reactive oxygen species production
    • Rodrigues C.M., Fan G., Wong P.Y., Kren B.T., and Steer C.J. Ursodeoxycholic acid may inhibit deoxycholic acid-induced apoptosis by modulating mitochondrial transmembrane potential and reactive oxygen species production. Mol. Med. 4 (1998) 165-178
    • (1998) Mol. Med. , vol.4 , pp. 165-178
    • Rodrigues, C.M.1    Fan, G.2    Wong, P.Y.3    Kren, B.T.4    Steer, C.J.5
  • 7
    • 0041322990 scopus 로고    scopus 로고
    • Bile salt-induced hepatocyte apoptosis involves epidermal growth factor receptor-dependent CD95 tyrosine phosphorylation
    • Reinehr R., Graf D., and Haussinger D. Bile salt-induced hepatocyte apoptosis involves epidermal growth factor receptor-dependent CD95 tyrosine phosphorylation. Gastroenterology 125 (2003) 839-853
    • (2003) Gastroenterology , vol.125 , pp. 839-853
    • Reinehr, R.1    Graf, D.2    Haussinger, D.3
  • 8
    • 0036098552 scopus 로고    scopus 로고
    • AP-1 as a regulator of cell life and death
    • Shaulian E., and Karin M. AP-1 as a regulator of cell life and death. Nat. Cell Biol. 4 (2002) E131-E136
    • (2002) Nat. Cell Biol. , vol.4
    • Shaulian, E.1    Karin, M.2
  • 9
    • 0035971493 scopus 로고    scopus 로고
    • AP-1 in cell proliferation and survival
    • Shaulian E., and Karin M. AP-1 in cell proliferation and survival. Oncogene 20 (2001) 2390-2400
    • (2001) Oncogene , vol.20 , pp. 2390-2400
    • Shaulian, E.1    Karin, M.2
  • 10
    • 30144436018 scopus 로고    scopus 로고
    • The human transcription factor AP-1 is a mediator of bile acid-induced liver cell apoptosis
    • Bernt C., Vennegeerts T., Beuers U., and Rust C. The human transcription factor AP-1 is a mediator of bile acid-induced liver cell apoptosis. Biochem. Biophys. Res. Commun. 340 (2006) 800-806
    • (2006) Biochem. Biophys. Res. Commun. , vol.340 , pp. 800-806
    • Bernt, C.1    Vennegeerts, T.2    Beuers, U.3    Rust, C.4
  • 11
    • 24644435870 scopus 로고    scopus 로고
    • Medical treatment of primary biliary cirrhosis and primary sclerosing cholangitis
    • Rust C., and Beuers U. Medical treatment of primary biliary cirrhosis and primary sclerosing cholangitis. Clin. Rev. Allergy Immunol. 28 (2005) 135-145
    • (2005) Clin. Rev. Allergy Immunol. , vol.28 , pp. 135-145
    • Rust, C.1    Beuers, U.2
  • 12
    • 0034102505 scopus 로고    scopus 로고
    • Effect of tauroursodeoxycholic acid on bile acid-induced apoptosis in primary human hepatocytes
    • Benz C., Angermuller S., Otto G., Sauer P., Stremmel W., and Stiehl A. Effect of tauroursodeoxycholic acid on bile acid-induced apoptosis in primary human hepatocytes. Eur. J. Clin. Invest. 30 (2000) 203-209
    • (2000) Eur. J. Clin. Invest. , vol.30 , pp. 203-209
    • Benz, C.1    Angermuller, S.2    Otto, G.3    Sauer, P.4    Stremmel, W.5    Stiehl, A.6
  • 13
    • 0032525819 scopus 로고    scopus 로고
    • A novel role for ursodeoxycholic acid in inhibiting apoptosis by modulating mitochondrial membrane perturbation
    • Rodrigues C.M., Fan G., Ma X., Kren B.T., and Steer C.J. A novel role for ursodeoxycholic acid in inhibiting apoptosis by modulating mitochondrial membrane perturbation. J. Clin. Invest. 101 (1998) 2790-2799
    • (1998) J. Clin. Invest. , vol.101 , pp. 2790-2799
    • Rodrigues, C.M.1    Fan, G.2    Ma, X.3    Kren, B.T.4    Steer, C.J.5
  • 15
    • 0037910211 scopus 로고    scopus 로고
    • The future of GI and liver research: editorial perspectives. III. JNK/AP-1 regulation of hepatocyte death
    • Czaja M.J. The future of GI and liver research: editorial perspectives. III. JNK/AP-1 regulation of hepatocyte death. Am. J. Physiol. Gastrointest. Liver Physiol. 284 (2003) G875-G879
    • (2003) Am. J. Physiol. Gastrointest. Liver Physiol. , vol.284
    • Czaja, M.J.1
  • 16
    • 0037366092 scopus 로고    scopus 로고
    • Curcumin alters EpRE and AP-1 binding complexes and elevates glutamate-cysteine ligase gene expression
    • Dickinson D.A., Iles K.E., Zhang H., Blank V., and Forman H.J. Curcumin alters EpRE and AP-1 binding complexes and elevates glutamate-cysteine ligase gene expression. FASEB J. 17 (2003) 473-475
    • (2003) FASEB J. , vol.17 , pp. 473-475
    • Dickinson, D.A.1    Iles, K.E.2    Zhang, H.3    Blank, V.4    Forman, H.J.5
  • 18
    • 0032537814 scopus 로고    scopus 로고
    • Inhibition of the c-Jun N-terminal kinase (JNK) signaling pathway by curcumin
    • Chen Y.R., and Tan T.H. Inhibition of the c-Jun N-terminal kinase (JNK) signaling pathway by curcumin. Oncogene 17 (1998) 173-178
    • (1998) Oncogene , vol.17 , pp. 173-178
    • Chen, Y.R.1    Tan, T.H.2
  • 21
    • 0032869839 scopus 로고    scopus 로고
    • Hepatocyte apoptosis after bile duct ligation in the mouse involves Fas
    • Miyoshi H., Rust C., Roberts P.J., Burgart L.J., and Gores G.J. Hepatocyte apoptosis after bile duct ligation in the mouse involves Fas. Gastroenterology 117 (1999) 669-677
    • (1999) Gastroenterology , vol.117 , pp. 669-677
    • Miyoshi, H.1    Rust, C.2    Roberts, P.J.3    Burgart, L.J.4    Gores, G.J.5
  • 22
    • 0029123537 scopus 로고
    • Generation of hydroperoxides in isolated rat hepatocytes and hepatic mitochondria exposed to hydrophobic bile acids
    • Sokol R.J., Winklhofer-Roob B.M., Devereaux M.W., and McKim Jr. J.M. Generation of hydroperoxides in isolated rat hepatocytes and hepatic mitochondria exposed to hydrophobic bile acids. Gastroenterology 109 (1995) 1249-1256
    • (1995) Gastroenterology , vol.109 , pp. 1249-1256
    • Sokol, R.J.1    Winklhofer-Roob, B.M.2    Devereaux, M.W.3    McKim Jr., J.M.4
  • 23
    • 0035129976 scopus 로고    scopus 로고
    • Bile acid-induced rat hepatocyte apoptosis is inhibited by antioxidants and blockers of the mitochondrial permeability transition
    • Yerushalmi B., Dahl R., Devereaux M.W., Gumpricht E., and Sokol R.J. Bile acid-induced rat hepatocyte apoptosis is inhibited by antioxidants and blockers of the mitochondrial permeability transition. Hepatology 33 (2001) 616-626
    • (2001) Hepatology , vol.33 , pp. 616-626
    • Yerushalmi, B.1    Dahl, R.2    Devereaux, M.W.3    Gumpricht, E.4    Sokol, R.J.5
  • 24
    • 0029866680 scopus 로고    scopus 로고
    • Induction of the transcription factor AP-1 in cultured human colon adenocarcinoma cells following exposure to bile acids
    • Hirano F., Tanada H., Makino Y., Okamoto K., Hiramoto M., Handa H., and Makino I. Induction of the transcription factor AP-1 in cultured human colon adenocarcinoma cells following exposure to bile acids. Carcinogenesis 17 (1996) 427-433
    • (1996) Carcinogenesis , vol.17 , pp. 427-433
    • Hirano, F.1    Tanada, H.2    Makino, Y.3    Okamoto, K.4    Hiramoto, M.5    Handa, H.6    Makino, I.7
  • 25
    • 0033033117 scopus 로고    scopus 로고
    • Effects of colonic lumenal components on AP-1-dependent gene transcription in cultured human colon carcinoma cells
    • Glinghammar B., Holmberg K., and Rafter J. Effects of colonic lumenal components on AP-1-dependent gene transcription in cultured human colon carcinoma cells. Carcinogenesis 20 (1999) 969-976
    • (1999) Carcinogenesis , vol.20 , pp. 969-976
    • Glinghammar, B.1    Holmberg, K.2    Rafter, J.3
  • 26
    • 12344252237 scopus 로고    scopus 로고
    • AP-1 subunits: quarrel and harmony among siblings
    • Hess J., Angel P., and Schorpp-Kistner M. AP-1 subunits: quarrel and harmony among siblings. J. Cell Sci. 117 (2004) 5965-5973
    • (2004) J. Cell Sci. , vol.117 , pp. 5965-5973
    • Hess, J.1    Angel, P.2    Schorpp-Kistner, M.3
  • 27
    • 0242691046 scopus 로고    scopus 로고
    • AP-1: a double-edged sword in tumorigenesis
    • Eferl R., and Wagner E.F. AP-1: a double-edged sword in tumorigenesis. Nat. Rev. Cancer 3 (2003) 859-868
    • (2003) Nat. Rev. Cancer , vol.3 , pp. 859-868
    • Eferl, R.1    Wagner, E.F.2
  • 28
    • 33749433408 scopus 로고    scopus 로고
    • Modulation of hepatocyte apoptosis: cross-talk between bile acids and nuclear steroid receptors
    • Sola S., Amaral J.D., Aranha M.M., Steer C.J., and Rodrigues C.M. Modulation of hepatocyte apoptosis: cross-talk between bile acids and nuclear steroid receptors. Curr. Med. Chem. 13 (2006) 3039-3051
    • (2006) Curr. Med. Chem. , vol.13 , pp. 3039-3051
    • Sola, S.1    Amaral, J.D.2    Aranha, M.M.3    Steer, C.J.4    Rodrigues, C.M.5
  • 29
    • 0036204957 scopus 로고    scopus 로고
    • Ursodeoxycholic acid cytoprotection: dancing with death receptors and survival pathways
    • Guicciardi M.E., and Gores G.J. Ursodeoxycholic acid cytoprotection: dancing with death receptors and survival pathways. Hepatology 35 (2002) 971-973
    • (2002) Hepatology , vol.35 , pp. 971-973
    • Guicciardi, M.E.1    Gores, G.J.2
  • 31
    • 0032846812 scopus 로고    scopus 로고
    • Ursodeoxycholic acid prevents cytochrome c release in apoptosis by inhibiting mitochondrial membrane depolarization and channel formation
    • Rodrigues C.M., Ma X., Linehan-Stieers C., Fan G., Kren B.T., and Steer C.J. Ursodeoxycholic acid prevents cytochrome c release in apoptosis by inhibiting mitochondrial membrane depolarization and channel formation. Cell Death Differ. 6 (1999) 842-854
    • (1999) Cell Death Differ. , vol.6 , pp. 842-854
    • Rodrigues, C.M.1    Ma, X.2    Linehan-Stieers, C.3    Fan, G.4    Kren, B.T.5    Steer, C.J.6
  • 32
    • 0037452957 scopus 로고    scopus 로고
    • Tauroursodeoxycholic acid prevents Bax-induced membrane perturbation and cytochrome C release in isolated mitochondria
    • Rodrigues C.M., Sola S., Sharpe J.C., Moura J.J., and Steer C.J. Tauroursodeoxycholic acid prevents Bax-induced membrane perturbation and cytochrome C release in isolated mitochondria. Biochemistry 42 (2003) 3070-3080
    • (2003) Biochemistry , vol.42 , pp. 3070-3080
    • Rodrigues, C.M.1    Sola, S.2    Sharpe, J.C.3    Moura, J.J.4    Steer, C.J.5
  • 33
    • 1542467261 scopus 로고    scopus 로고
    • Ursodeoxycholic acid modulates E2F-1 and p53 expression through a caspase-independent mechanism in transforming growth factor beta1-induced apoptosis of rat hepatocytes
    • Sola S., Ma X., Castro R.E., Kren B.T., Steer C.J., and Rodrigues C.M. Ursodeoxycholic acid modulates E2F-1 and p53 expression through a caspase-independent mechanism in transforming growth factor beta1-induced apoptosis of rat hepatocytes. J. Biol. Chem. 278 (2003) 48831-48838
    • (2003) J. Biol. Chem. , vol.278 , pp. 48831-48838
    • Sola, S.1    Ma, X.2    Castro, R.E.3    Kren, B.T.4    Steer, C.J.5    Rodrigues, C.M.6
  • 34
    • 36348941176 scopus 로고    scopus 로고
    • p53 is a key molecular target of ursodeoxycholic acid in regulating apoptosis
    • Amaral J.D., Castro R.E., Sola S., Steer C.J., and Rodrigues C.M. p53 is a key molecular target of ursodeoxycholic acid in regulating apoptosis. J Biol. Chem. 282 (2007) 34250-34259
    • (2007) J Biol. Chem. , vol.282 , pp. 34250-34259
    • Amaral, J.D.1    Castro, R.E.2    Sola, S.3    Steer, C.J.4    Rodrigues, C.M.5
  • 36
    • 0942301272 scopus 로고    scopus 로고
    • Ursodeoxycholic acid (UDCA) can inhibit deoxycholic acid (DCA)-induced apoptosis via modulation of EGFR/Raf-1/ERK signaling in human colon cancer cells
    • Im E., and Martinez J.D. Ursodeoxycholic acid (UDCA) can inhibit deoxycholic acid (DCA)-induced apoptosis via modulation of EGFR/Raf-1/ERK signaling in human colon cancer cells. J. Nutr. 134 (2004) 483-486
    • (2004) J. Nutr. , vol.134 , pp. 483-486
    • Im, E.1    Martinez, J.D.2


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