메뉴 건너뛰기




Volumn 28, Issue 5, 2007, Pages 596-603

Effect of oral glucose on acylated and total Ghrelin secretion in acromegalic patients

Author keywords

Acromegaly; Acylated ghrelin; Oral glucose

Indexed keywords

GHRELIN; GLUCOSE; INSULIN;

EID: 38049018468     PISSN: 0172780X     EISSN: None     Source Type: Journal    
DOI: None     Document Type: Article
Times cited : (12)

References (64)
  • 1
    • 0036083399 scopus 로고    scopus 로고
    • Ghrelin stimulates insulin secretion from the pancreas of normal and diabetic rats
    • Adeghate E and Ponery AS (2002). Ghrelin stimulates insulin secretion from the pancreas of normal and diabetic rats. J Neuroendocrinol. 14: 555-560.
    • (2002) J Neuroendocrinol , vol.14 , pp. 555-560
    • Adeghate, E.1    Ponery, A.S.2
  • 2
    • 2342465508 scopus 로고    scopus 로고
    • Pharmacokinetics, safety, and endocrine and appetite effects of ghrelin administration in young healthy subjects
    • Akamizu T, Takaya K, Irako T, Hosoda H, Teramukai S, Matsuyama A, et al. (2004). Pharmacokinetics, safety, and endocrine and appetite effects of ghrelin administration in young healthy subjects. Eur J Endocrinol. 150: 447-455.
    • (2004) Eur J Endocrinol , vol.150 , pp. 447-455
    • Akamizu, T.1    Takaya, K.2    Irako, T.3    Hosoda, H.4    Teramukai, S.5    Matsuyama, A.6
  • 3
    • 4143057995 scopus 로고    scopus 로고
    • Marked GH secretion after ghrelin alone or combined with GH-releasing hormone (GHRH) in obese patients
    • Alvarez P, Isidro L, Garcia-Buela J, Leal-Cerro J, Broglio F, Tassone F, et al. (2004). Marked GH secretion after ghrelin alone or combined with GH-releasing hormone (GHRH) in obese patients. Clin Endocrinol. 61: 250-255.
    • (2004) Clin Endocrinol , vol.61 , pp. 250-255
    • Alvarez, P.1    Isidro, L.2    Garcia-Buela, J.3    Leal-Cerro, J.4    Broglio, F.5    Tassone, F.6
  • 5
    • 17944379112 scopus 로고    scopus 로고
    • Stomach is a major source of circulating ghrelin, and feeding state determines plasma ghrelin-like immunoreactivity levels in humans
    • Ariyasu H, Takaya K, Tagami T, Ogawa Y, Hosoda K, Akamizu T, et al. (2001). Stomach is a major source of circulating ghrelin, and feeding state determines plasma ghrelin-like immunoreactivity levels in humans. J Clin Endocrinol Metab. 86: 4753-4758.
    • (2001) J Clin Endocrinol Metab , vol.86 , pp. 4753-4758
    • Ariyasu, H.1    Takaya, K.2    Tagami, T.3    Ogawa, Y.4    Hosoda, K.5    Akamizu, T.6
  • 6
    • 0038304457 scopus 로고    scopus 로고
    • Antagonism of ghrelin receptor reduces food intake and body weight gain in mice
    • Asakawa A, Inui A, Kaga T, Katsuura G, Fujimiya M, Fujino MA, Kasuga M. (2003). Antagonism of ghrelin receptor reduces food intake and body weight gain in mice. Gut. 52: 947-952.
    • (2003) Gut , vol.52 , pp. 947-952
    • Asakawa, A.1    Inui, A.2    Kaga, T.3    Katsuura, G.4    Fujimiya, M.5    Fujino, M.A.6    Kasuga, M.7
  • 7
    • 0038030760 scopus 로고    scopus 로고
    • Ghrelin secretion in humans is sexually dimorphic, suppressed by somatostatin, and not affected by the ambient growth hormone levels
    • Barkan AL, Dimaraki EV, Jessup SK, Symons KV, Ermolenko M, Jaffe CA. (2003). Ghrelin secretion in humans is sexually dimorphic, suppressed by somatostatin, and not affected by the ambient growth hormone levels. J Clin Endocrinol Metab. 88: 2180-2184.
    • (2003) J Clin Endocrinol Metab , vol.88 , pp. 2180-2184
    • Barkan, A.L.1    Dimaraki, E.V.2    Jessup, S.K.3    Symons, K.V.4    Ermolenko, M.5    Jaffe, C.A.6
  • 9
    • 0034751526 scopus 로고    scopus 로고
    • Ghrelin, a natural GH secretagogue produced by the stomach, induces hyperglycemia and reduces insulin secretion in humans
    • Broglio F, Arvat E, Benso A, Gottero C, Muccioli G, Papotti M, et al. (2001). Ghrelin, a natural GH secretagogue produced by the stomach, induces hyperglycemia and reduces insulin secretion in humans. J Clin Endocrinol Metab. 86: 5083-6.
    • (2001) J Clin Endocrinol Metab , vol.86 , pp. 5083-5086
    • Broglio, F.1    Arvat, E.2    Benso, A.3    Gottero, C.4    Muccioli, G.5    Papotti, M.6
  • 11
    • 0141453037 scopus 로고    scopus 로고
    • Effects of ghrelin on the insulin and glycemic responses to glucose, arginine, or free fatty acids load in humans
    • Broglio F, Gottero C, Benso A, Prodam F, Destefanis S, Gauna C, et al. (2003b). Effects of ghrelin on the insulin and glycemic responses to glucose, arginine, or free fatty acids load in humans. J Clin Endocrinol Metab. 88: 4268-4272.
    • (2003) J Clin Endocrinol Metab , vol.88 , pp. 4268-4272
    • Broglio, F.1    Gottero, C.2    Benso, A.3    Prodam, F.4    Destefanis, S.5    Gauna, C.6
  • 13
    • 0036677654 scopus 로고    scopus 로고
    • Circulating ghrelin levels in basal conditions and during glucose tolerance test in acromegalic patients
    • Cappiello V, Ronchi C, Mospurgo PS, Epaminonda P, Beck-Peccoz P, Spada A. (2002). Circulating ghrelin levels in basal conditions and during glucose tolerance test in acromegalic patients. Eur J Endocrinol. 147: 189-194.
    • (2002) Eur J Endocrinol , vol.147 , pp. 189-194
    • Cappiello, V.1    Ronchi, C.2    Mospurgo, P.S.3    Epaminonda, P.4    Beck-Peccoz, P.5    Spada, A.6
  • 14
    • 0027419864 scopus 로고
    • Massive growth hormone (GH) discharge in obese subjects after the combined administration of Growth Hormone releasing hormone and GHRP-6: Evidence for a marked somatotroph secretory capability in obesity
    • Cordido F, Peñalva A, Dieguez C and Casanueva F. (1993). Massive growth hormone (GH) discharge in obese subjects after the combined administration of Growth Hormone releasing hormone and GHRP-6: evidence for a marked somatotroph secretory capability in obesity. J Clin Endocrinol Metab. 76: 819-823.
    • (1993) J Clin Endocrinol Metab , vol.76 , pp. 819-823
    • Cordido, F.1    Peñalva, A.2    Dieguez, C.3    Casanueva, F.4
  • 17
    • 0035433977 scopus 로고    scopus 로고
    • A preprandial rise in plasma ghrelin levels suggests a role in meal initiation in humans
    • Cummings DE, Purnell JQ, Frayo RS, Schmidova K, Wisse BE, Weigle DS. (2001). A preprandial rise in plasma ghrelin levels suggests a role in meal initiation in humans. Diabetes. 50: 1714-1719.
    • (2001) Diabetes , vol.50 , pp. 1714-1719
    • Cummings, D.E.1    Purnell, J.Q.2    Frayo, R.S.3    Schmidova, K.4    Wisse, B.E.5    Weigle, D.S.6
  • 18
    • 0036316624 scopus 로고    scopus 로고
    • Plasma ghrelin levels during exercise in healthy subjects and in growth hormone-deficient patients
    • Dall R, Kanaley J, Hanse TK, Moller N, Christiansen JS, Hosoda H, et al. (2002). Plasma ghrelin levels during exercise in healthy subjects and in growth hormone-deficient patients. Eur J Endocrinol. 147: 65-70.
    • (2002) Eur J Endocrinol , vol.147 , pp. 65-70
    • Dall, R.1    Kanaley, J.2    Hanse, T.K.3    Moller, N.4    Christiansen, J.S.5    Hosoda, H.6
  • 19
    • 0036097362 scopus 로고    scopus 로고
    • Ghrelin is present in pancreatic alpha-cells of humans and rats and stimulates insulin secretion
    • Date Y, Nakazato M, Hashiguchi S, Dezaki K, Mondal MS, Hosoda H, et al. (2002). Ghrelin is present in pancreatic alpha-cells of humans and rats and stimulates insulin secretion. Diabetes. 51: 124-129.
    • (2002) Diabetes , vol.51 , pp. 124-129
    • Date, Y.1    Nakazato, M.2    Hashiguchi, S.3    Dezaki, K.4    Mondal, M.S.5    Hosoda, H.6
  • 21
    • 0036181821 scopus 로고    scopus 로고
    • Inhibitory effect of ghrelin on insulin and pancreatic somatostatin secretion
    • Egido EM, Rodriguez-Gallardo J, Silvestre RA and Marco J (2002). Inhibitory effect of ghrelin on insulin and pancreatic somatostatin secretion. Eur J Endocrinol. 146: 241-244.
    • (2002) Eur J Endocrinol , vol.146 , pp. 241-244
    • Egido, E.M.1    Rodriguez-Gallardo, J.2    Silvestre, R.A.3    Marco, J.4
  • 22
    • 14044256656 scopus 로고    scopus 로고
    • Fasting unmasks a strong inverse association between ghrelin and cortisol in serum: Studies in obese and normal-weight subjects
    • Espelund U, Hansen TK, Hojlund K, Beck-Nielsen H, Clausen JT, Hansen BS, et al. (2005). Fasting unmasks a strong inverse association between ghrelin and cortisol in serum: Studies in obese and normal-weight subjects. J Clin Endocrinol Metab. 90: 741-746.
    • (2005) J Clin Endocrinol Metab , vol.90 , pp. 741-746
    • Espelund, U.1    Hansen, T.K.2    Hojlund, K.3    Beck-Nielsen, H.4    Clausen, J.T.5    Hansen, B.S.6
  • 24
    • 6344291317 scopus 로고    scopus 로고
    • Administration of acylated ghrelin reduces insulin sensitivity, whereas the combination of acylated plus unacylated ghrelin strongly improves insulin sensitivity
    • Gauna C, Meyler FM, Janssen J, Delhanty PJD, Abribat T, van Koetsveld P, et al. (2004). Administration of acylated ghrelin reduces insulin sensitivity, whereas the combination of acylated plus unacylated ghrelin strongly improves insulin sensitivity. J Clin Endocrinol Metab. 89: 5035-5042.
    • (2004) J Clin Endocrinol Metab , vol.89 , pp. 5035-5042
    • Gauna, C.1    Meyler, F.M.2    Janssen, J.3    Delhanty, P.J.D.4    Abribat, T.5    van Koetsveld, P.6
  • 25
    • 3242719361 scopus 로고    scopus 로고
    • Different effects of short- and long-term recombinant hGH administration on ghrelin and adiponectin levels in GH-deficient adults
    • Giavoli C, Cappiello V, Corbetta S, Ronchi CL, Morpugo PS, Ferrante E, et al. (2004). Different effects of short- and long-term recombinant hGH administration on ghrelin and adiponectin levels in GH-deficient adults. Clin Endocrinol. 61: 81-87.
    • (2004) Clin Endocrinol , vol.61 , pp. 81-87
    • Giavoli, C.1    Cappiello, V.2    Corbetta, S.3    Ronchi, C.L.4    Morpugo, P.S.5    Ferrante, E.6
  • 26
    • 0037240916 scopus 로고    scopus 로고
    • Serum ghrelin levels are inversely correlated with body mass index, age, and insulin concentrations in normal children and are markedly increased in Prader-Willi syndrome
    • Haqq AM, Farooqi IS, O'Rahilly S, Stadler DD, Rosenfeld RG, Prat KL, et al. (2003). Serum ghrelin levels are inversely correlated with body mass index, age, and insulin concentrations in normal children and are markedly increased in Prader-Willi syndrome. J Clin Endocrinol Metab. 88: 174-178.
    • (2003) J Clin Endocrinol Metab , vol.88 , pp. 174-178
    • Haqq, A.M.1    Farooqi, I.S.2    O'Rahilly, S.3    Stadler, D.D.4    Rosenfeld, R.G.5    Prat, K.L.6
  • 27
    • 33644991326 scopus 로고    scopus 로고
    • Homocysteine levels in acromegaly patients
    • Hekimsoy Z, Ozmen B, Ulusoy (2005). Homocysteine levels in acromegaly patients. Neuro Endocrinol Lett. 26: 811-814.
    • (2005) Neuro Endocrinol Lett , vol.26 , pp. 811-814
    • Hekimsoy, Z.1    Ozmen, B.2    Ulusoy3
  • 29
    • 0035214675 scopus 로고    scopus 로고
    • Systemic ghrelin levels in subjects with growth hormone deficiency are not modified by one year of growth hormone replacement therapy
    • Janssen A van der Toorn FM, Hofland LJ, van Koetsveld P, Broglio F, Ghigo E, et al. (2002). Systemic ghrelin levels in subjects with growth hormone deficiency are not modified by one year of growth hormone replacement therapy. Eur J Endocrinol. 145: 711-716.
    • (2002) Eur J Endocrinol , vol.145 , pp. 711-716
    • Janssen, A.1    van der Toorn, F.M.2    Hofland, L.J.3    van Koetsveld, P.4    Broglio, F.5    Ghigo, E.6
  • 30
    • 33646134378 scopus 로고    scopus 로고
    • Plasma levels of total and active ghrelin in acromegaly and growth hormone deficiency
    • Jarkovska Z, Rosicka M, Marek J, Hana V, Weiss V, Justova V, et al. (2006). Plasma levels of total and active ghrelin in acromegaly and growth hormone deficiency. Physiol Res. 55: 175-181.
    • (2006) Physiol Res , vol.55 , pp. 175-181
    • Jarkovska, Z.1    Rosicka, M.2    Marek, J.3    Hana, V.4    Weiss, V.5    Justova, V.6
  • 32
    • 34147157240 scopus 로고    scopus 로고
    • Acylated ghrelin secretion is acutely suppressed by oral glucose load or insulin-induced hypoglycaemia independently of basal growth hormone secretion in humans
    • Kim SW, Kim KW, Shin CS, Park DJ, Park KS, Cho BY et al. (2006). Acylated ghrelin secretion is acutely suppressed by oral glucose load or insulin-induced hypoglycaemia independently of basal growth hormone secretion in humans. Horm Res. 67: 211-219.
    • (2006) Horm Res , vol.67 , pp. 211-219
    • Kim, S.W.1    Kim, K.W.2    Shin, C.S.3    Park, D.J.4    Park, K.S.5    Cho, B.Y.6
  • 33
    • 0033540056 scopus 로고    scopus 로고
    • Ghrelin is a growth hormone-releasing acylated peptide from stomach
    • Kojima M, Hosoda H, Date Y, Nakazato M, Matsuo H, Kangawa K. (1999). Ghrelin is a growth hormone-releasing acylated peptide from stomach. Nature 402: 656-658.
    • (1999) Nature , vol.402 , pp. 656-658
    • Kojima, M.1    Hosoda, H.2    Date, Y.3    Nakazato, M.4    Matsuo, H.5    Kangawa, K.6
  • 34
    • 15544385058 scopus 로고    scopus 로고
    • Ghrelin: Structure and function
    • Kojima M and Kangawa K (2005). Ghrelin: Structure and function. Physiol Rev. 85: 495-522.
    • (2005) Physiol Rev , vol.85 , pp. 495-522
    • Kojima, M.1    Kangawa, K.2
  • 35
    • 33750140948 scopus 로고    scopus 로고
    • Decreased in serum ghrelin levels in patients with acromegaly normalize after successful surgical treatment
    • Kozakowski J, Rabijewski M and Zgliczynski W (2005). Decreased in serum ghrelin levels in patients with acromegaly normalize after successful surgical treatment. Endokrynol Pol. 56: 862-870.
    • (2005) Endokrynol Pol , vol.56 , pp. 862-870
    • Kozakowski, J.1    Rabijewski, M.2    Zgliczynski, W.3
  • 36
    • 0036141195 scopus 로고    scopus 로고
    • Ghrelin, a new gastrointestinal endocrine peptide that stimulates insulin secretion: Enteric distribution, ontogeny, influence of endocrine, and dietary manipulations
    • Lee HM, Wang G, Englander EW, Kojima M, Greeley Jr GH (2002). Ghrelin, a new gastrointestinal endocrine peptide that stimulates insulin secretion: enteric distribution, ontogeny, influence of endocrine, and dietary manipulations. Endocrinology. 143: 185-190.
    • (2002) Endocrinology , vol.143 , pp. 185-190
    • Lee, H.M.1    Wang, G.2    Englander, E.W.3    Kojima, M.4    Greeley Jr, G.H.5
  • 37
    • 0036789176 scopus 로고    scopus 로고
    • Ghrelin is not necessary for adequate hormonal counterregulation of insulin-induced hypoglycaemia
    • Lucidi P, Murdolo G, Di Loreto G, De Cicco A, Parlanti N, Fanelli C et al. (2002). Ghrelin is not necessary for adequate hormonal counterregulation of insulin-induced hypoglycaemia. Diabetes. 51: 2911-2914.
    • (2002) Diabetes , vol.51 , pp. 2911-2914
    • Lucidi, P.1    Murdolo, G.2    Di Loreto, G.3    De Cicco, A.4    Parlanti, N.5    Fanelli, C.6
  • 39
    • 0021813187 scopus 로고
    • Homeostasis model assessment: Insulin resistance and beta-cell function from fasting plasma glucose and insulin concentrations in man
    • Matthews DR, Hosker JP, Rudenski AS, Naylor DB, Treacher DF, Turner RC. (1985) Homeostasis model assessment: insulin resistance and beta-cell function from fasting plasma glucose and insulin concentrations in man. Diabetologia. 28: 412-419.
    • (1985) Diabetologia , vol.28 , pp. 412-419
    • Matthews, D.R.1    Hosker, J.P.2    Rudenski, A.S.3    Naylor, D.B.4    Treacher, D.F.5    Turner, R.C.6
  • 40
    • 1942473108 scopus 로고    scopus 로고
    • Plasma ghrelin concentrations are decreased in insulin-resistant obese adults relative to equally obese insulin-sensitive controls
    • McLaughlin T, Abbasi F, Lamendola C, Frayo RS, Cummings DE. (2004). Plasma ghrelin concentrations are decreased in insulin-resistant obese adults relative to equally obese insulin-sensitive controls. J Clin Endocrinol Metab. 89: 1630-1635.
    • (2004) J Clin Endocrinol Metab , vol.89 , pp. 1630-1635
    • McLaughlin, T.1    Abbasi, F.2    Lamendola, C.3    Frayo, R.S.4    Cummings, D.E.5
  • 41
    • 33845491265 scopus 로고    scopus 로고
    • Acromegaly
    • Melmed S (2006). Acromegaly. N Engl J Med 355: 2558-73.
    • (2006) N Engl J Med , vol.355 , pp. 2558-2573
    • Melmed, S.1
  • 42
    • 0037066587 scopus 로고    scopus 로고
    • Neuroendocrine and peripheral activities of ghrelin: Implications in metabolism and obesity
    • Muccioli G, Tschop M, Papotti M, Deghenghi R, Heiman M, Ghigo E. (2002). Neuroendocrine and peripheral activities of ghrelin: implications in metabolism and obesity. Eur J Pharmacol. 440: 235-254.
    • (2002) Eur J Pharmacol , vol.440 , pp. 235-254
    • Muccioli, G.1    Tschop, M.2    Papotti, M.3    Deghenghi, R.4    Heiman, M.5    Ghigo, E.6
  • 44
    • 4444243109 scopus 로고    scopus 로고
    • Chronic changes in peripheral growth hormone levels do not affect ghrelin stomach mRNA expression and serum ghrelin levels in three transgenic mouse models
    • Nass R, Liu J, Hellmann P, Coschigano KT, Gaylinn B, Berryman DE, et al. (2004). Chronic changes in peripheral growth hormone levels do not affect ghrelin stomach mRNA expression and serum ghrelin levels in three transgenic mouse models. J Neuroendocrinol 16: 669-675.
    • (2004) J Neuroendocrinol , vol.16 , pp. 669-675
    • Nass, R.1    Liu, J.2    Hellmann, P.3    Coschigano, K.T.4    Gaylinn, B.5    Berryman, D.E.6
  • 46
    • 13444265857 scopus 로고    scopus 로고
    • Weight gain decreases elevated plasma ghrelin concentrations of patients with anorexia nervosa
    • Otto B, Cuntz U, Fruehauf E, Wawarta R, Folwaczny C, Riepl RL, et al. (2001). Weight gain decreases elevated plasma ghrelin concentrations of patients with anorexia nervosa. Eur J Endocrinol. 145: 669-673.
    • (2001) Eur J Endocrinol , vol.145 , pp. 669-673
    • Otto, B.1    Cuntz, U.2    Fruehauf, E.3    Wawarta, R.4    Folwaczny, C.5    Riepl, R.L.6
  • 47
    • 32844466580 scopus 로고    scopus 로고
    • Acute plasma ghrelin and leptin responses to oral feeding or intraperitoneal hypertonic glucose-based dialysate in patients with chronic renal failure
    • Pérez-Fontán M, Cordido F, Rodríguez-Carmona A, García-Naveiro R, Isidro ML, Villaverde P, García-Buela J. (2005). Acute plasma ghrelin and leptin responses to oral feeding or intraperitoneal hypertonic glucose-based dialysate in patients with chronic renal failure. Kidney Int. 68: 2877-2885.
    • (2005) Kidney Int , vol.68 , pp. 2877-2885
    • Pérez-Fontán, M.1    Cordido, F.2    Rodríguez-Carmona, A.3    García-Naveiro, R.4    Isidro, M.L.5    Villaverde, P.6    García-Buela, J.7
  • 48
    • 0346101851 scopus 로고    scopus 로고
    • Ghrelin levels correlate with insulin levels, insulin resistance, and high-density lipoprotein cholesterol, but not with gender, menopausal status, or cortisol levels in humans
    • Purnell JQ, Weigle DS, Breen P, Cummings DE. (2003). Ghrelin levels correlate with insulin levels, insulin resistance, and high-density lipoprotein cholesterol, but not with gender, menopausal status, or cortisol levels in humans. J Clin Endocrinol Metab. 88: 5747-5752.
    • (2003) J Clin Endocrinol Metab , vol.88 , pp. 5747-5752
    • Purnell, J.Q.1    Weigle, D.S.2    Breen, P.3    Cummings, D.E.4
  • 49
    • 0037372044 scopus 로고    scopus 로고
    • Dose-dependent inhibition by ghrelin of insulin secretion in the mouse
    • Reimer MK, Pacini G and Ahrén B (2003). Dose-dependent inhibition by ghrelin of insulin secretion in the mouse. Endocrinology 144: 916-921.
    • (2003) Endocrinology , vol.144 , pp. 916-921
    • Reimer, M.K.1    Pacini, G.2    Ahrén, B.3
  • 51
    • 0037220691 scopus 로고    scopus 로고
    • Plasma ghrelin concentrations are not regulated by glucose or insulin: A double-blind, placebo-controlled crossover clamp study
    • Schaller G, Schmidt A, Pleiner J, Woloszczuk W, Woltz M, Luger A. (2003). Plasma ghrelin concentrations are not regulated by glucose or insulin: a double-blind, placebo-controlled crossover clamp study. Diabetes. 5: 16-20.
    • (2003) Diabetes , vol.5 , pp. 16-20
    • Schaller, G.1    Schmidt, A.2    Pleiner, J.3    Woloszczuk, W.4    Woltz, M.5    Luger, A.6
  • 52
    • 18244391222 scopus 로고    scopus 로고
    • Plasma ghrelin levels in lean and obese humans and the effect of glucose on ghrelin secretion
    • Shiiya T, Nakazato M, Mizuta M, Date Y, Mondal MS, Tanaka M, et al. (2002). Plasma ghrelin levels in lean and obese humans and the effect of glucose on ghrelin secretion. J Clin Endocrinol Metab. 87: 240-244.
    • (2002) J Clin Endocrinol Metab , vol.87 , pp. 240-244
    • Shiiya, T.1    Nakazato, M.2    Mizuta, M.3    Date, Y.4    Mondal, M.S.5    Tanaka, M.6
  • 53
    • 0036263016 scopus 로고    scopus 로고
    • Hypothalamic growth hormone secretagogue receptor regulates growth hormone secretion, feeding and adiposity
    • Shuto Y, Shibasaki T, Otagiri A, Kuriyama H, Ohata H, Tamura H, et al. (2002). Hypothalamic growth hormone secretagogue receptor regulates growth hormone secretion, feeding and adiposity. J Clin Invest. 109: 1429-1436.
    • (2002) J Clin Invest , vol.109 , pp. 1429-1436
    • Shuto, Y.1    Shibasaki, T.2    Otagiri, A.3    Kuriyama, H.4    Ohata, H.5    Tamura, H.6
  • 55
    • 0034687376 scopus 로고    scopus 로고
    • Ghrelin induces adiposity in rodents
    • Tschop M, Smiley DL and Heiman ML (2000). Ghrelin induces adiposity in rodents. Nature. 407: 908-909.
    • (2000) Nature , vol.407 , pp. 908-909
    • Tschop, M.1    Smiley, D.L.2    Heiman, M.L.3
  • 57
    • 0037355648 scopus 로고    scopus 로고
    • Ghrelin and insulin metabolism
    • Ukkola O (2003). Ghrelin and insulin metabolism. Eur J Clin Invest. 33: 183-185.
    • (2003) Eur J Clin Invest , vol.33 , pp. 183-185
    • Ukkola, O.1
  • 58
    • 2942528459 scopus 로고    scopus 로고
    • Biological, physiological, pathophysiological, and pharmacological aspects of ghrelin
    • van der Lely AJ, Tschop M, Heiman ML, Ghigo E. (2004). Biological, physiological, pathophysiological, and pharmacological aspects of ghrelin. Endoc Rev. 25: 426-457.
    • (2004) Endoc Rev , vol.25 , pp. 426-457
    • van der Lely, A.J.1    Tschop, M.2    Heiman, M.L.3    Ghigo, E.4
  • 59
    • 0036679260 scopus 로고    scopus 로고
    • Central ghrelin production does not substantially contribute to systemic ghrelin concentration: A study inn two subjects with active acromegaly
    • Van der Toorn FM, Janssen JA, de Herder WW, Broglio F, Ghigo E, van der Lely AJ. (2002). Central ghrelin production does not substantially contribute to systemic ghrelin concentration: a study inn two subjects with active acromegaly. Eur J Endocrinol. 147: 195-199.
    • (2002) Eur J Endocrinol , vol.147 , pp. 195-199
    • Van der Toorn, F.M.1    Janssen, J.A.2    de Herder, W.W.3    Broglio, F.4    Ghigo, E.5    van der Lely, A.J.6
  • 61
    • 0036959760 scopus 로고    scopus 로고
    • Expression of ghrelin and the GH secretagogue receptor by the pancreatic islet cells and related endocrine tumors
    • Volante M, Allia E, Gugliotta P, Funaro A, Broglio F, Deghenghi R. (2002). Expression of ghrelin and the GH secretagogue receptor by the pancreatic islet cells and related endocrine tumors. J Clin Endocrinol Metab. 87: 1300-1308.
    • (2002) J Clin Endocrinol Metab , vol.87 , pp. 1300-1308
    • Volante, M.1    Allia, E.2    Gugliotta, P.3    Funaro, A.4    Broglio, F.5    Deghenghi, R.6
  • 63
    • 0037098974 scopus 로고    scopus 로고
    • The ghrelin cell: A novel developmentally regulated islet cell in the human pancreas
    • Wierup N, Svensson H, Mulder H, Sundler F (2002). The ghrelin cell: a novel developmentally regulated islet cell in the human pancreas. Reg Pept. 107: 63-69
    • (2002) Reg Pept , vol.107 , pp. 63-69
    • Wierup, N.1    Svensson, H.2    Mulder, H.3    Sundler, F.4


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.