Synthesis and pharmacological evaluation of fluorescent and photoactivatable analogues of antiplasmodial naphthylisoquinolines

Journal of Medicinal Chemistry

Volumn 50, Issue 24, 2007, Pages 6104-6115

  Bringmann, Gerhard ^a   Gampe, Christian M ^a   Reichert, Yanina ^a   Bruhn, Torsten ^a   Faber, Johan H ^a   Mikyna, Martin ^a   Reichert, Matthias ^a   Leippe, Matthias ^b   Brun, Reto ^c   Gelhaus, Christoph ^b  

^a UNIVERSITY OF WÜRZBURG   (Germany)

^b UNIVERSITY OF KIEL   (Germany)

^c SWISS TROPICAL AND PUBLIC HEALTH INSTITUTE   (Switzerland)

Author keywords

[No Author keywords available]

Indexed keywords

3 (DIONCOPHYLLINE A 5 YL) N PROPYL N DANSYL O (4 BENZOYLBENZYLOXY) 1 TYROSINECARBAMINATE; 3 (DIONCOPHYLLINE A 5 YL)PROPAN 1 OL; 3 (N,8 O DIBENZYLDIONCOPHYLLINE A 5 YL) 2 PROPEN 1 OL; 5 [N' (1'',6'' HEXANEDIAMINO N'' DANSYL)]METHYLDIONCOPHYLLINE; ALKALOID; ANTIPROTOZOAL AGENT; CHLOROQUINE; DIONCOPHYLLINE A; ISOQUINOLINE DERIVATIVE; N,8 O DIBENZYL 5 [N' (1'',6'' HEXANEDIAMINO N'' DANSYL)]METHYLDIONCOPHYLLINE A; NAPHTHYL GROUP; PODOPHYLLOTOXIN; UNCLASSIFIED DRUG;

ANCISTROCLADACEAE; ANIMAL CELL; ANTIPROTOZOAL ACTIVITY; ARTICLE; CONTROLLED STUDY; DIONCOPHYLLACEAE; DRUG CYTOTOXICITY; DRUG SCREENING; DRUG SYNTHESIS; IN VITRO STUDY; IN VIVO STUDY; MALARIA; MEDICINAL PLANT; NONHUMAN; PLASMODIUM FALCIPARUM; STRUCTURE ACTIVITY RELATION;

ALKALOIDS; ANIMALS; ANTIMALARIALS; FLUORESCENT DYES; ISOQUINOLINES; NAPHTHALENES; PHOTOAFFINITY LABELS; PLASMODIUM FALCIPARUM; STRUCTURE-ACTIVITY RELATIONSHIP;

EID: 37849033508     PISSN: 00222623     EISSN: None     Source Type: Journal    
DOI: 10.1021/jm061464w     Document Type: Article

References (59)

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