Quercetin accelerates TNF-α-induced apoptosis of MC3T3-E1 osteoblastic cells through caspase-dependent and JNK-mediated pathways

European Journal of Pharmacology

Volumn 579, Issue 1-3, 2008, Pages 26-33

  Son, Young Ok ^a   Kook, Sung Ho ^a   Choi, Ki Choon ^b   Jang, Yong Suk ^a   Choi, Yong Sung ^a   Jeon, Young Mi ^a   Kim, Jong Ghee ^a   Hwang, Hyeon Shik ^c   Lee, Jeong Chae ^a  

^a Chonbuk National University   (South Korea)

^b Hallym Unversity College of Medicine   (South Korea)

^c Chonnam National University   (South Korea)

Author keywords

Apoptosis; Caspase; JNK; Osteoblastic cells; Quercetin; TNF

Indexed keywords

2 (2 AMINO 3 METHOXYPHENYL)CHROMONE; 4 (4 FLUOROPHENYL) 2 (4 METHYLSULFINYLPHENYL) 5 (4 PYRIDYL)IMIDAZOLE; ANTHRA[1,9 CD]PYRAZOL 6(2H) ONE; BENZYLOXYCARBONYLISOLEUCYLGLUTAMYLTHREONYLASPARTYL FLUOROMETHYL KETONE; BENZYLOXYCARBONYLLEUCYLGLUTAMYLHISTIDYLASPARTYL FLUOROMETHYL KETONE; CASPASE; CYSTEINE PROTEINASE INHIBITOR; FK 009; FK 023; FK 029; PROTEIN C JUN; Q 0125; QUERCETIN; STRESS ACTIVATED PROTEIN KINASE; TRANSCRIPTION FACTOR AP 1; TUMOR NECROSIS FACTOR ALPHA; UNCLASSIFIED DRUG;

ANIMAL CELL; APOPTOSIS; ARTICLE; BONE CELL; BONE DEVELOPMENT; CELL CULTURE; CONTROLLED STUDY; DRUG MECHANISM; ENZYME ACTIVATION; MITOCHONDRION; MOUSE; NONHUMAN; OSTEOBLAST; PRIORITY JOURNAL;

3T3 CELLS; ANIMALS; ANTIOXIDANTS; APOPTOSIS; CASPASES; JNK MITOGEN-ACTIVATED PROTEIN KINASES; MICE; MITOCHONDRIA; OSTEOBLASTS; QUERCETIN; TRANSCRIPTION FACTOR AP-1; TUMOR NECROSIS FACTOR-ALPHA;

EID: 37649023276     PISSN: 00142999     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.ejphar.2007.10.003     Document Type: Article

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