Inhibiting nitric oxide overproduction during hypotensive sepsis increases local oxygen consumption in rat skeletal muscle

Critical Care Medicine

Volumn 36, Issue 1, 2008, Pages 225-231

  Bateman, Ryon M ^a,d   Sharpe, Michael D ^b   Goldman, Daniel ^c   Lidington, Darcy ^a   Ellis, Christopher G ^a  

^a UNIVERSITY OF WESTERN ONTARIO   (Canada)

^b Program in Critical Care Medicine   (Canada)

^c NEW JERSEY INSTITUTE OF TECHNOLOGY   (United States)

^d KEIO UNIVERSITY   (Japan)

Author keywords

Capillaries; Microcirculation; Nitric oxide; Oxygen consumption; Sepsis

Indexed keywords

HEMOGLOBIN; INDUCIBLE NITRIC OXIDE SYNTHASE; N6 (1 IMINOETHYL)LYSINE; NITRIC OXIDE; NITRIC OXIDE SYNTHASE INHIBITOR;

ANIMAL EXPERIMENT; ANIMAL MODEL; ARTERIAL BLOOD; ARTICLE; BODY WEIGHT; CAPILLARY DENSITY; CONTROLLED STUDY; DRUG MECHANISM; ENZYME INHIBITION; ERYTHROCYTE; EXPERIMENTAL ANIMAL; EXTENSOR DIGITORUM LONGUS MUSCLE; FLUID RESUSCITATION; HEMODYNAMICS; HYPOTENSION; HYPOTENSIVE SEPSIS; IN VIVO STUDY; LEG; LIGATION; MALE; MEAN ARTERIAL PRESSURE; MICROCIRCULATION; MICROVASCULATURE; NONHUMAN; OXYGEN CONSUMPTION; OXYGEN DIFFUSION; OXYGEN SATURATION; OXYGEN TRANSPORT; PERFORATION; PRIORITY JOURNAL; PROSPECTIVE STUDY; RAT; SEPSIS; SKELETAL MUSCLE; SPRAGUE DAWLEY RAT; TISSUE OXYGENATION;

EID: 37549056565     PISSN: 00903493     EISSN: None     Source Type: Journal    
DOI: 10.1097/01.CCM.0000295307.92027.2F     Document Type: Article

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