Phorbol 12-myristate 13-acetate-activated protein kinase C increased migratory activity of subconjunctival fibroblasts via stress-activated protein kinase pathways

Molecular Vision

Volumn 13, Issue , 2007, Pages 2320-2327

  Nomura, Naoko ^a   Nomura, Motohiro ^b   Takahira, Masayuki ^a   Sugiyama, Kazuhisa ^a  

^a KANAZAWA UNIVERSITY GRADUATE SCHOOL OF MEDICAL SCIENCE   (Japan)

^b Yokohama Sakae Kyosai Hospital   (Japan)

Author keywords

[No Author keywords available]

Indexed keywords

ACTIN; HEAT SHOCK PROTEIN 27; MITOGEN ACTIVATED PROTEIN KINASE P38; PHORBOL 13 ACETATE 12 MYRISTATE; PROTEIN KINASE C; PROTEIN KINASE C ALPHA; PROTEIN KINASE C BETA; PROTEIN KINASE C DELTA; PROTEIN KINASE C EPSILON; PROTEIN KINASE C GAMMA; PROTEIN KINASE C INHIBITOR; PROTEIN KINASE C IOTA; PROTEIN KINASE C LAMBDA; STRESS ACTIVATED PROTEIN KINASE;

ANIMAL CELL; ARTICLE; CELL ISOLATION; CELL MIGRATION; CONTROLLED STUDY; CULTURE MEDIUM; CYTOSKELETON; ENZYME ACTIVATION; ENZYME PHOSPHORYLATION; FIBROBLAST; IMMUNOFLUORESCENCE; LAMELLIPODIUM; MALE; NONHUMAN; PRIORITY JOURNAL; RAT; UPREGULATION; WESTERN BLOTTING; WOUND HEALING;

ACTINS; ANIMALS; ANTHRACENES; CELL MOVEMENT; CELLS, CULTURED; CONJUNCTIVA; ENZYME ACTIVATION; FIBROBLASTS; IMIDAZOLES; JNK MITOGEN-ACTIVATED PROTEIN KINASES; MALE; MITOGEN-ACTIVATED PROTEIN KINASES; PHOSPHORYLATION; PROTEIN KINASE C; PSEUDOPODIA; PYRIDINES; RATS; RATS, WISTAR; SIGNAL TRANSDUCTION; TETRADECANOYLPHORBOL ACETATE;

EID: 37549050904     PISSN: None     EISSN: 10900535     Source Type: Journal    
DOI: None     Document Type: Article

References (27)

1. Esson DW, Neelakantan A, Iyer SA, Blalock TD, Balasubramanian L, Grotendorst GR, Schultz GS, Sherwood MB. Expression of connective tissue growth factor after glaucoma filtration surgery in a rabbit model. Invest Ophthalmol Vis Sci 2004; 45:485-91.
2. Lama PJ, Fechtner RD. Antifibrotics and wound healing in glaucoma surgery. Surv Ophthalmol 2003; 48:314-46.
3. Richards TS, Dunn CA, Carter WG, Usui ML, Olerud JE, Lampe PD. Protein kinase C spatially and temporally regulates gap junctional communication during human wound repair via phosphorylation of connexin43 on serine368. J Cell Biol 2004; 167:555-62.
4. Farhadi A, Keshavarzian A, Ranjbaran Z, Fields JZ, Banan A. The role of protein kinase C isoforms in modulating injury and repair of the intestinal barrier. J Pharmacol Exp Ther 2006; 316: 1-7.
5. Ron D, Kazanietz MG. New insights into the regulation of protein kinase C and novel phorbol ester receptors. FASEB J 1999; 13:1658-76.
6. Larsson C. Protein kinase C and the regulation of the actin cytoskeleton. Cell Signal 2006; 18:276-84.
7. Harrington EO, Loffler J, Nelson PR, Kent KC, Simons M, Ware JA. Enhancement of migration by protein kinase Calpha and inhibition of proliferation and cell cycle progression by protein kinase Cdelta in capillary endothelial cells. J Biol Chem 1997; 272:7390-7.
8. Besson A, Davy A, Robbins SM, Yong VW. Differential activation of ERKs to focal adhesions by PKC epsilon is required for PMA-induced adhesion and migration of human glioma cells. Oncogene 2001; 20:7398-407.
9. Huang C,, Jacobson K, Schaller MD. MAP kinases and cell migration. J Cell Sci 2004; 117:4619-28.
10. Kay EP, Lee HK, Park KS, Lee SC. Indirect mitogenic effect of transforming growth factor-beta on cell proliferation of subconjunctival fibroblasts. Invest Opthalmol Vis Sci 1998; 39:481-6.
11. Petit V, Boyer B, Lentz D, Turner CE, Thiery JP, Valles AM. Phosphorylation of tyrosine residues 31 and 118 on paxillin regulates cell migration through an association with CRK in NBT-II cells. J Cell Biol 2000; 148:957-70.
12. Gillies MC, Su T. Cytokines, fibrosis and the failure of glaucoma filtration surgery. Aust N Z J Ophthalmol 1991; 19:299-304.
13. Skuta GL, Parrish RK 2nd. Wound healing in glaucoma filtering surgery. Surv Opthalmol 1987; 32:149-70.
14. Toullec D, Pianetti P, Coste H, Bellevergue P, Grand-perret T, Ajakane M, Baudet V, Boissin P, Boursier E, Loriolle F, Duhame L, Charon D, Kirilovsky J. The bisindolylmaleimide GF 109203X is a potent and selective inhibitor of protein kinase C. J Biol Chem 1991; 266:15771-81.
15. Martiny-Baron G, Kazanietz MG, Mischak H, Blumberg PM, Kochs G, Hug H, Marme D, Schachtele C. Selective inhibition of protein kinase C isozymes by the indolocarbazole Go 6976. J Biol Chem 1993; 268:9194-7.
16. Javelaud D, Laboureau J, Gabison E, Verrecchia F, Mauviel A. Disruption of basal JNK activity differentially affects key fibroblast functions important for wound healing. J Biol Chem 2003; 278:24624-8.
17. Hedges JC, Dechert MA, Yamboliev IA, Martin JL, Hickey E, Weber LA, Gerthoffer WT. A role for p38(MAPK)/HSP27 pathway in smooth muscle cell migration. J Biol Chem 1999; 274:24211-9.
18. Butt E, Immler D, Meyer HE, Kotlyarov A, Laass K, Gaestel M. Heat shock protein 27 is a substrate of cGMP-dependent protein kinase in intact human platelets: phosphorylation-induced actin polymerization caused by HSP27 mutants. J Biol Chem 2001; 276:7108-13.
19. Cuenda A, Rouse J, Doza YN, Meier R, Cohen P, Gallagher TF, Young PR, Lee JC. SB 203580 is a specific inhibitor of a MAP kinase homologue which is stimulated by cellular stresses and interleukin-1. FEBS Lett 1995; 364:229-33.
20. Kumar S, Orsini MJ, Lee JC, McDonnell PC, Debouck C, Young PR. Activation of the HIV-1 long terminal repeat by cytokines and environmental stress requires an active CSBP/p38 MAP kinase. J Biol Chem 1996; 271:30864-9.
21. Clerk A, Kemp TJ, Harrison JG, Mullen AJ, Barton PJ, Sugden PH. Up-regulation of c-jun mRNA in cardiac myocytes requires the extracellular signal-regulated kinase cascade, but c-Jun N-terminal kinases are required for efficient up-regulation of c-Jun protein. Biochem J 2002; 368:101-10.
22. Chang MR, Cheng Q, Lee DA. Basic science and clinical aspects of wound healing in glaucoma filtering surgery. J Ocul Pharmacol Ther 1998; 14:75-95.
23. White SR, Tse R, Marroquin BA. Stress-activated protein kinases mediate cell migration in human airway epithelial cells. Am J Respir Cell Mol Biol 2005; 32:301-10.
24. Ioroi T, Yamamori M, Yagi K, Hirai M, Zhan Y, Kim S, Iwao H. Dominant negative c-Jun inhibits platelet-derived growth factor-directed migration by vascular smooth muscle cells. J Pharmacol Sci 2003; 91:145-8.
25. Ray AK, Jones AC, Carnes, DL, Cochran DL, Mellonig JT, Oates TW Jr. Platelet-derived growth factor-BB stimulated cell migration mediated through p38 signal transduction pathway in periodontal cells. J Periodontol 2003; 74:1320-8.
26. Ono K, Han J. The p38 signal transduction pathway: activation and function. Cell Signal 2000; 12:1-13.
27. Rousseau S, Houle F, Landry J, Huot J. p38 MAP kinase activation by vascular endothelial growth factor mediates actin reorganization and cell migration in human endothelial cells. Oncogene 1997; 15:2169-77.