Heat shock protein 27 is a substrate of cGMP-dependent protein kinase in intact human platelets. Phosphorylation-induced actin polymerization caused by HSP27 mutants

Journal of Biological Chemistry

Volumn 276, Issue 10, 2001, Pages 7108-7113

  Butt, Elke ^a   Immler, Dorian ^b,c   Meyer, Helmut E ^c   Kotlyarov, Alexey ^d   Laaß, Kathrin ^d   Gaestel, Matthias ^d  

^a UNIVERSITY HOSPITAL WÜRZBURG   (Germany)

^b BAYER AG   (Germany)

^c RUHR UNIVERSITY BOCHUM   (Germany)

^d MARTIN LUTHER UNIVERSITY HALLE WITTENBERG   (Germany)

Author keywords

[No Author keywords available]

Indexed keywords

AMINO ACIDS; MUTAGENESIS; PHOSPHATES; POLYMERIZATION; PROTEINS;

PHOSPHORYLATION;

BIOCHEMISTRY;

8 (4 CHLOROPHENYLTHIO) CYCLIC GMP; CYCLIC GMP DEPENDENT PROTEIN KINASE; CYCLIC GMP DERIVATIVE; G ACTIN; HEAT SHOCK PROTEIN 27; MITOGEN ACTIVATED PROTEIN KINASE ACTIVATED PROTEIN KINASE 2; MUTANT PROTEIN; PHOSPHORUS 32; PROTEIN KINASE; SERINE; THREONINE; UNCLASSIFIED DRUG; 8 ((4 CHLOROPHENYL)THIO)CYCLIC 3',5' GMP; 8-((4-CHLOROPHENYL)THIO)CYCLIC-3',5'-GMP; ACTIN; CYCLIC GMP; DRUG DERIVATIVE; HEAT SHOCK PROTEIN; HSPB1 PROTEIN, HUMAN; MAP KINASE ACTIVATED KINASE 2; MAP-KINASE-ACTIVATED KINASE 2; MITOGEN ACTIVATED PROTEIN KINASE; MITOGEN ACTIVATED PROTEIN KINASE P38; NUCLEOTIDE; PROTEIN SERINE THREONINE KINASE; TUMOR PROTEIN;

ACTIN FILAMENT; ACTIN POLYMERIZATION; ARTICLE; CONTROLLED STUDY; ENZYME SUBSTRATE; HUMAN; HUMAN CELL; MASS SPECTROMETRY; NONHUMAN; PRIORITY JOURNAL; PROTEIN PHOSPHORYLATION; THROMBOCYTE; THROMBOCYTE ACTIVATION; THROMBOCYTE AGGREGATION INHIBITION; TWO DIMENSIONAL GEL ELECTROPHORESIS; BINDING SITE; CHEMISTRY; ELECTROSPRAY MASS SPECTROMETRY; ENZYME SPECIFICITY; METABOLISM; PHOSPHORYLATION; POLYACRYLAMIDE GEL ELECTROPHORESIS; SIGNAL TRANSDUCTION; SITE DIRECTED MUTAGENESIS; SPECTROFLUOROMETRY; THROMBOCYTE AGGREGATION; TIME; WESTERN BLOTTING;

ACTINS; BINDING SITES; BLOOD PLATELETS; BLOTTING, WESTERN; CYCLIC GMP; CYCLIC GMP-DEPENDENT PROTEIN KINASES; ELECTROPHORESIS, GEL, TWO-DIMENSIONAL; ELECTROPHORESIS, POLYACRYLAMIDE GEL; HEAT-SHOCK PROTEINS; HUMANS; MASS SPECTROMETRY; MITOGEN-ACTIVATED PROTEIN KINASES; MUTAGENESIS, SITE-DIRECTED; NEOPLASM PROTEINS; P38 MITOGEN-ACTIVATED PROTEIN KINASES; PHOSPHORYLATION; PLATELET AGGREGATION; PROTEIN-SERINE-THREONINE KINASES; SERINE; SIGNAL TRANSDUCTION; SPECTROMETRY, FLUORESCENCE; SPECTROMETRY, MASS, ELECTROSPRAY IONIZATION; SUBSTRATE SPECIFICITY; THIONUCLEOTIDES; THREONINE; TIME FACTORS;

EID: 0035831438     PISSN: 00219258     EISSN: None     Source Type: Journal    
DOI: 10.1074/jbc.M009234200     Document Type: Article

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