Complement C1q-target proteins recognition is inhibited by electric moment effectors

Journal of Molecular Recognition

Volumn 20, Issue 5, 2007, Pages 405-415

  Roumenina, Lubka ^a   Bureeva, Svetlana ^b   Kantardjiev, Alexander ^c   Karlinsky, David ^b,d   Andia Pravdivy, Julian E ^b   Sim, Robert ^e   Kaplun, Alexander ^b   Popov, Michael ^d   Kishore, Uday ^f   Atanasov, Boris ^c  

^a UNIVERSITY OF SOFIA   (Bulgaria)

^b MIREA RUSSIAN TECHNOLOGICAL UNIVERSITY   (Russian Federation)

^c INSTITUTE OF ORGANIC CHEMISTRY   (Bulgaria)

^d SHEMYAKIN OVCHINNIKOV INSTITUTE OF BIOORGANIC CHEMISTRY   (Russian Federation)

^e UNIVERSITY OF OXFORD   (United Kingdom)

^f BRUNEL UNIVERSITY   (United Kingdom)

Author keywords

C1q activation; Classical pathway inhibitor; Disulphates binding; Electric moments under Ca2+ control; Electrostatic recognition

Indexed keywords

C REACTIVE PROTEIN; COMPLEMENT COMPONENT C1Q; IMMUNOGLOBULIN G; PENTRAXIN 3; RECOMBINANT PROTEIN; SERUM AMYLOID P; SULFATE;

ARTICLE; CHEMICAL STRUCTURE; CHEMISTRY; DRUG EFFECT; ELECTRICITY; ENZYME LINKED IMMUNOSORBENT ASSAY; ENZYME SPECIFICITY; HUMAN; IC 50; METABOLISM; PH; PROTEIN BINDING; PROTEIN TERTIARY STRUCTURE; THERMODYNAMICS; X RAY CRYSTALLOGRAPHY;

C-REACTIVE PROTEIN; COMPLEMENT C1Q; CRYSTALLOGRAPHY, X-RAY; ELECTROSTATICS; ENZYME-LINKED IMMUNOSORBENT ASSAY; HUMANS; HYDROGEN-ION CONCENTRATION; IMMUNOGLOBULIN G; INHIBITORY CONCENTRATION 50; MODELS, MOLECULAR; PROTEIN BINDING; PROTEIN STRUCTURE, TERTIARY; RECOMBINANT PROTEINS; SERUM AMYLOID P-COMPONENT; SUBSTRATE SPECIFICITY; SULFATES; THERMODYNAMICS;

EID: 37549042068     PISSN: 09523499     EISSN: 10991352     Source Type: Journal    
DOI: 10.1002/jmr.853     Document Type: Article

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