Mass spectrometry analysis of the oligomeric C1q protein reveals the B chain as the target of trypsin cleavage and interaction with fucoidan

Biochemistry

Volumn 44, Issue 7, 2005, Pages 2602-2609

  Tissot, Bérangère ^b   Gonnet, Florence ^a   Iborra, Alban ^a   Berthou, Christian ^b   Thielens, Nicole ^c   Arlaud, Gérard J ^c   Daniel, Régis ^a  

^a UNIVERSITÉ D EVRY VAL D ESSONNE   (France)

^b CHU MORVAN   (France)

^c INSTITUT DE BIOLOGIE STRUCTURALE   (France)

Author keywords

[No Author keywords available]

Indexed keywords

ACTIVATION ENERGY; DESORPTION; IONIZATION; MASS SPECTROMETRY; OLIGOMERS; POLYSACCHARIDES;

ANTICOMPLEMENTARY AGENTS; HETEROTRIMERS; IMMUNE COMPLEXES; NONCOVALENT INTERACTIONS;

PROTEINS;

COMPLEMENT COMPONENT C1Q; DISULFIDE; DNA; FUCOIDIN; IMMUNOGLOBULIN G; OLIGOMER; POLYSACCHARIDE; POLYSACCHARIDE SULFATE; REDUCED NICOTINAMIDE ADENINE DINUCLEOTIDE DEHYDROGENASE (UBIQUINONE); TRYPSIN;

ANTIGEN ANTIBODY COMPLEX; ANTIGEN RECOGNITION; ARTICLE; COMPLEMENT ACTIVATION; COMPLEMENT CLASSICAL PATHWAY; COVALENT BOND; LIGAND BINDING; MASS SPECTROMETRY; MATRIX ASSISTED LASER DESORPTION IONIZATION TIME OF FLIGHT MASS SPECTROMETRY; NONHUMAN; PRIORITY JOURNAL; PROTEIN ANALYSIS; PROTEIN DEGRADATION; PROTEIN INTERACTION;

AMINO ACID SEQUENCE; ANIMALS; CARBOHYDRATE SEQUENCE; CATTLE; COMPLEMENT C1Q; ELECTROPHORESIS, POLYACRYLAMIDE GEL; HUMANS; HYDROLYSIS; MOLECULAR SEQUENCE DATA; PEPTIDE FRAGMENTS; POLYSACCHARIDES; PROTEIN SUBUNITS; SERINE PROTEINASE INHIBITORS; SPECTROMETRY, MASS, MATRIX-ASSISTED LASER DESORPTION-IONIZATION; TRYPSIN;

EID: 14044258721     PISSN: 00062960     EISSN: None     Source Type: Journal    
DOI: 10.1021/bi047802h     Document Type: Article

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