Selective inhibition of the interaction of C1q with immunoglobulins and the classical pathway of complement activation by steroids and triterpenoids sulfates

Bioorganic and Medicinal Chemistry

Volumn 15, Issue 10, 2007, Pages 3489-3498

  Bureeva, Svetlana ^a   Andia Pravdivy, Julian ^a   Symon, Andrey ^a   Bichucher, Anna ^b   Moskaleva, Vera ^a   Popenko, Vladimir ^c   Shpak, Alexey ^d   Shvets, Vitaly ^a   Kozlov, Leonid ^b   Kaplun, Alexander ^a  

^a MIREA RUSSIAN TECHNOLOGICAL UNIVERSITY   (Russian Federation)

^b GN Gabrichevsky Moscow Research Institute of Epidemiology and Microbiology   (Russian Federation)

^c ENGELHARDT INSTITUTE OF MOLECULAR BIOLOGY   (Russian Federation)

^d MOSCOW STATE UNIVERSITY   (Russian Federation)

Author keywords

Betulin; Complement system; Inhibitors; Steroid; Sulfate; Triterpenoid

Indexed keywords

20,29 DIHYDRO 20,29 DICHLOROMETHYLENBETULIN DISULFATE; 3BETA HYDROXY DELTA5 CHOLENIC ACID SULFATE; 3BETA HYDROXY DELTA5 ETIOCHOLENIC ACID SULFATE; BETULIC ACID; BETULIN; BETULIN DIPHOSPHATE; BETULIN DISULFATE; BETULINIC ACID SULFATE; CHOLIC ACID; CHOLIC ACID TRISULFATE; COMPLEMENT COMPONENT C1Q; DEOXYCHOLIC ACID; DEOXYCHOLIC ACID DISULFATE; IMMUNOGLOBULIN; OLEANOLIC ACID; OLEANOLIC ACID SULFATE; PENTRAXIN; STEROID; SULFUR DERIVATIVE; TERPENOID DERIVATIVE; TRITERPENOID; UNCLASSIFIED DRUG; URSOLIC ACID; URSOLIC ACID SULFATE;

ANIMAL CELL; APOPTOSIS; ARTICLE; AUTOIMMUNE DISEASE; COMPLEMENT ACTIVATION; COMPLEMENT CLASSICAL PATHWAY; COMPLEMENT SYSTEM; GRAFT REJECTION; INFLAMMATION; ISCHEMIA; MOLECULAR INTERACTION; NONHUMAN; PROTEIN BINDING; PROTEIN TARGETING; REPERFUSION INJURY; SYNTHESIS; TISSUE INJURY; XENOGRAFT;

ANIMALS; COMPLEMENT C1Q; COMPLEMENT PATHWAY, CLASSICAL; GUINEA PIGS; HEMOLYSIS; HUMANS; IMMUNOGLOBULINS; INDICATORS AND REAGENTS; MAGNETIC RESONANCE SPECTROSCOPY; MICROSCOPY, ELECTRON; MOLECULAR CONFORMATION; SHEEP; STEROIDS; TRITERPENES;

EID: 34047190395     PISSN: 09680896     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.bmc.2007.03.002     Document Type: Article

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