Structural biology of the C1 complex of complement unveils the mechanisms of its activation and proteolytic activity

Molecular Immunology

Volumn 39, Issue 7-8, 2002, Pages 383-394

  Arlaud, Gérard J ^a   Gaboriaud, Christine ^a   Thielens, Nicole M ^a   Budayova Spano, Monika ^a   Rossi, Véronique ^a   Fontecilla Camps, Juan Carlos ^a  

^a INSTITUT DE BIOLOGIE STRUCTURALE   (France)

Author keywords

C1; Complement; Innate immunity; Molecular recognition; Protein modules; Serine protease

Indexed keywords

CALCIUM ION; COMPLEMENT COMPONENT C1Q; COMPLEMENT COMPONENT C1R; COMPLEMENT COMPONENT C1S;

CATALYSIS; CHEMICAL ANALYSIS; COMPLEMENT ACTIVATION; ELECTRON MICROSCOPY; ENZYME ISOLATION; ENZYME STRUCTURE; ENZYME SUBUNIT; HOST RESISTANCE; HUMAN; IMMUNOLOGICAL TOLERANCE; MOLECULAR RECOGNITION; NONHUMAN; NUCLEAR MAGNETIC RESONANCE SPECTROSCOPY; PRIORITY JOURNAL; PROTEIN ASSEMBLY; PROTEIN DEGRADATION; PROTEIN FUNCTION; REVIEW; X RAY CRYSTALLOGRAPHY;

ANIMALS; CATALYTIC DOMAIN; COMPLEMENT ACTIVATION; COMPLEMENT C1; COMPLEMENT C1Q; CRYSTALLOGRAPHY, X-RAY; EPIDERMAL GROWTH FACTOR; HUMANS; MAGNETIC RESONANCE SPECTROSCOPY; PROTEIN STRUCTURE, SECONDARY; SERINE ENDOPEPTIDASES;

EID: 0036844317     PISSN: 01615890     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0161-5890(02)00143-8     Document Type: Review

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