-
2
-
-
0037456354
-
One-year outcomes in survivors of the acute respiratory distress syndrome
-
Herridge MS, Cheung AM, Tansey CM, et al. One-year outcomes in survivors of the acute respiratory distress syndrome. N Engl J Med 2003; 348:683-694
-
(2003)
N Engl J Med
, vol.348
, pp. 683-694
-
-
Herridge, M.S.1
Cheung, A.M.2
Tansey, C.M.3
-
3
-
-
8544268686
-
The effect of drotrecogin alfa (activated) on long-term survival after severe sepsis
-
Angus DC, Laterre PF, Helterbrand J, et al. The effect of drotrecogin alfa (activated) on long-term survival after severe sepsis. Crit Care Med 2004; 32:2199-2206
-
(2004)
Crit Care Med
, vol.32
, pp. 2199-2206
-
-
Angus, D.C.1
Laterre, P.F.2
Helterbrand, J.3
-
4
-
-
33745622134
-
Procalcitonin as a diagnostic test for sepsis in critically ill adults and after surgery or trauma: A systematic review and meta-analysis
-
Uzzan B, Cohen R, Nicolas P, et al. Procalcitonin as a diagnostic test for sepsis in critically ill adults and after surgery or trauma: a systematic review and meta-analysis. Crit Care Med 2006; 34:1996-2003
-
(2006)
Crit Care Med
, vol.34
, pp. 1996-2003
-
-
Uzzan, B.1
Cohen, R.2
Nicolas, P.3
-
5
-
-
17044422667
-
Time-course of sTREM (soluble triggering receptor expressed on myeloid cells)-1, procalcitonin, and C-reactive protein plasma concentrations during sepsis
-
Gibot S, Cravoisy A, Kolopp-Sarda MN, et al. Time-course of sTREM (soluble triggering receptor expressed on myeloid cells)-1, procalcitonin, and C-reactive protein plasma concentrations during sepsis. Crit Care Med 2005; 33:792-796
-
(2005)
Crit Care Med
, vol.33
, pp. 792-796
-
-
Gibot, S.1
Cravoisy, A.2
Kolopp-Sarda, M.N.3
-
6
-
-
33747179285
-
International Society on Thrombosis and Haemostasis score for overt disseminated intravascular coagulation predicts organ dysfunction and fatality in sepsis patients
-
Voves C, Wuillemin WA, Zeerleder S. International Society on Thrombosis and Haemostasis score for overt disseminated intravascular coagulation predicts organ dysfunction and fatality in sepsis patients. Blood Coagul Fibrinolysis 2006; 17:445-451
-
(2006)
Blood Coagul Fibrinolysis
, vol.17
, pp. 445-451
-
-
Voves, C.1
Wuillemin, W.A.2
Zeerleder, S.3
-
7
-
-
0035421655
-
Diagnostic value of procalcitonin, interleukin-6, and interleukin-8 in critically ill patients admitted with suspected sepsis
-
Harbarth S, Holeckova K, Froidevaux C, et al. Diagnostic value of procalcitonin, interleukin-6, and interleukin-8 in critically ill patients admitted with suspected sepsis. Am J Respir Crit Care Med 2001; 164:396-402
-
(2001)
Am J Respir Crit Care Med
, vol.164
, pp. 396-402
-
-
Harbarth, S.1
Holeckova, K.2
Froidevaux, C.3
-
8
-
-
34247550884
-
Protein C concentrations in severe sepsis: An early directional change in plasma levels predicts outcome
-
Shorr AF, Bernard GR, Dhainaut JF, et al. Protein C concentrations in severe sepsis: an early directional change in plasma levels predicts outcome. Crit Care 2006; 10:R92
-
(2006)
Crit Care
, vol.10
-
-
Shorr, A.F.1
Bernard, G.R.2
Dhainaut, J.F.3
-
10
-
-
0041329604
-
Epidemiology of severe sepsis occurring in the first 24 hrs in intensive care units in England, Wales, and Northern Ireland
-
Padkin A, Goldfrad C, Brady AR, et al. Epidemiology of severe sepsis occurring in the first 24 hrs in intensive care units in England, Wales, and Northern Ireland. Crit Care Med 2003; 31:2332-2338
-
(2003)
Crit Care Med
, vol.31
, pp. 2332-2338
-
-
Padkin, A.1
Goldfrad, C.2
Brady, A.R.3
-
11
-
-
0035829842
-
Early goal-directed therapy in the treatment of severe sepsis and septic shock
-
Rivers E, Nguyen B, Havstad S, et al. Early goal-directed therapy in the treatment of severe sepsis and septic shock. N Engl J Med 2001; 345:1368-1377
-
(2001)
N Engl J Med
, vol.345
, pp. 1368-1377
-
-
Rivers, E.1
Nguyen, B.2
Havstad, S.3
-
12
-
-
1842478877
-
Coagulation in sepsis: All bugs bite equally
-
Levi M, van der Poll T. Coagulation in sepsis: all bugs bite equally. Crit Care 2004; 8:99-100
-
(2004)
Crit Care
, vol.8
, pp. 99-100
-
-
Levi, M.1
van der Poll, T.2
-
13
-
-
1842600276
-
Universal changes in biomarkers of coagulation and inflammation occur in patients with severe sepsis, regardless of causative micro-organism
-
Kinasewitz GT, Yan SB, Basson B, et al. Universal changes in biomarkers of coagulation and inflammation occur in patients with severe sepsis, regardless of causative micro-organism. Crit Care 2004; 8:R82-R90
-
(2004)
Crit Care
, vol.8
-
-
Kinasewitz, G.T.1
Yan, S.B.2
Basson, B.3
-
14
-
-
0037897393
-
Systemic host responses in severe sepsis analyzed by causative microorganism and treatment effects of drotrecogin alfa (activated)
-
Opal SM, Garber GE, LaRosa SP, et al. Systemic host responses in severe sepsis analyzed by causative microorganism and treatment effects of drotrecogin alfa (activated). Clin Infect Dis 2003; 37:50-58
-
(2003)
Clin Infect Dis
, vol.37
, pp. 50-58
-
-
Opal, S.M.1
Garber, G.E.2
LaRosa, S.P.3
-
15
-
-
13444283302
-
Dynamic evolution of coagulopathy in the first day of severe sepsis: Relationship with mortality and organ failure
-
Dhainaut JF, Shorr AF, Macias WL, et al. Dynamic evolution of coagulopathy in the first day of severe sepsis: relationship with mortality and organ failure. Crit Care Med 2005; 33: 341-348
-
(2005)
Crit Care Med
, vol.33
, pp. 341-348
-
-
Dhainaut, J.F.1
Shorr, A.F.2
Macias, W.L.3
-
16
-
-
13644264883
-
Shock on admission day is the best predictor of prolonged mechanical ventilation in the ICU
-
Estenssoro E, Gonzalez F, Laffaire E, et al. Shock on admission day is the best predictor of prolonged mechanical ventilation in the ICU. Chest 2005; 127:598-603
-
(2005)
Chest
, vol.127
, pp. 598-603
-
-
Estenssoro, E.1
Gonzalez, F.2
Laffaire, E.3
-
17
-
-
0037451929
-
The epidemiology of sepsis in the United States from 1979 through 2000
-
Martin GS, Mannino DM, Eaton S, et al. The epidemiology of sepsis in the United States from 1979 through 2000. N Engl J Med 2003; 348:1546-1554
-
(2003)
N Engl J Med
, vol.348
, pp. 1546-1554
-
-
Martin, G.S.1
Mannino, D.M.2
Eaton, S.3
-
18
-
-
26444545385
-
Early changes in organ function predict eventual survival in severe sepsis
-
Levy MM, Macias WL, Vincent JL, et al. Early changes in organ function predict eventual survival in severe sepsis. Crit Care Med 2005; 33:2194-2201
-
(2005)
Crit Care Med
, vol.33
, pp. 2194-2201
-
-
Levy, M.M.1
Macias, W.L.2
Vincent, J.L.3
-
19
-
-
33745146498
-
The epidemiology of sepsis in patients with malignancy
-
Danai PA, Moss M, Mannino DM, et al. The epidemiology of sepsis in patients with malignancy. Chest 2006; 129:1432-1440
-
(2006)
Chest
, vol.129
, pp. 1432-1440
-
-
Danai, P.A.1
Moss, M.2
Mannino, D.M.3
-
20
-
-
29744447480
-
The effect of age on the development and outcome of adult sepsis
-
Martin GS, Mannino DM, Moss M. The effect of age on the development and outcome of adult sepsis. Crit Care Med 2006; 34:15-21
-
(2006)
Crit Care Med
, vol.34
, pp. 15-21
-
-
Martin, G.S.1
Mannino, D.M.2
Moss, M.3
-
21
-
-
31344461826
-
Sepsis in European intensive care units: Results of the SOAP study
-
Vincent JL, Sakr Y, Sprung CL, et al. Sepsis in European intensive care units: results of the SOAP study. Crit Care Med 2006; 34:552-554
-
(2006)
Crit Care Med
, vol.34
, pp. 552-554
-
-
Vincent, J.L.1
Sakr, Y.2
Sprung, C.L.3
-
22
-
-
37549040770
-
Data from the top ten enrolling countries contained in the PROGRESS registry demonstrates variations in treatment and high mortality rates [abstract]
-
Reinhart K, Vincent J-L, Ramsay G, et al. Data from the top ten enrolling countries contained in the PROGRESS registry demonstrates variations in treatment and high mortality rates [abstract]. Chest 2005; 128:377S
-
(2005)
Chest
, vol.128
-
-
Reinhart, K.1
Vincent, J.-L.2
Ramsay, G.3
-
23
-
-
3943052086
-
Early lactate clearance is associated with improved outcome in severe sepsis and septic shock
-
Nguyen HB, Rivers EP, Knoblich BP, et al. Early lactate clearance is associated with improved outcome in severe sepsis and septic shock. Crit Care Med 2004; 32:1637-1642
-
(2004)
Crit Care Med
, vol.32
, pp. 1637-1642
-
-
Nguyen, H.B.1
Rivers, E.P.2
Knoblich, B.P.3
-
24
-
-
2942744467
-
Severe protein C deficiency predicts early death in severe sepsis
-
Macias WL. Severe protein C deficiency predicts early death in severe sepsis. Crit Care Med 2004; 32:S223-S228
-
(2004)
Crit Care Med
, vol.32
-
-
Macias, W.L.1
-
25
-
-
4444233598
-
Persistent microcirculatory alterations are associated with organ failure and death in patients with septic shock
-
Sakr Y. Persistent microcirculatory alterations are associated with organ failure and death in patients with septic shock. Crit Care Med 2004; 32:1825-1831
-
(2004)
Crit Care Med
, vol.32
, pp. 1825-1831
-
-
Sakr, Y.1
-
26
-
-
0037588986
-
The role of the endothelium in severe sepsis and multiple organ dysfunction syndrome
-
Aird WC. The role of the endothelium in severe sepsis and multiple organ dysfunction syndrome. Blood 2003; 101:3765-3777
-
(2003)
Blood
, vol.101
, pp. 3765-3777
-
-
Aird, W.C.1
-
27
-
-
0037426726
-
The pathophysiology and treatment of sepsis
-
Hotchkiss RS, Karl IE. The pathophysiology and treatment of sepsis. N Engl J Med 2003; 348:138-150
-
(2003)
N Engl J Med
, vol.348
, pp. 138-150
-
-
Hotchkiss, R.S.1
Karl, I.E.2
-
30
-
-
28844494086
-
An epidemic, toxin gene variant strain of Clostridium difficile
-
McDonald LC, Killgore GE, Thompson A, et al. An epidemic, toxin gene variant strain of Clostridium difficile. N Engl J Med 2005; 353:2433-2441
-
(2005)
N Engl J Med
, vol.353
, pp. 2433-2441
-
-
McDonald, L.C.1
Killgore, G.E.2
Thompson, A.3
-
31
-
-
8744306050
-
The effect of an education program on the incidence of central venous catheter-associated bloodstream infection in a medical ICU
-
Warren DK, Zack JE, Mayfield JL, et al. The effect of an education program on the incidence of central venous catheter-associated bloodstream infection in a medical ICU. Chest 2004; 126:1612-1618
-
(2004)
Chest
, vol.126
, pp. 1612-1618
-
-
Warren, D.K.1
Zack, J.E.2
Mayfield, J.L.3
-
32
-
-
5644300386
-
Eliminating catheter-related bloodstream infections in the intensive care unit
-
Berenholtz SM, Pronovost PJ, Lipsett PA, et al. Eliminating catheter-related bloodstream infections in the intensive care unit. Crit Care Med 2004; 32:2014-2020
-
(2004)
Crit Care Med
, vol.32
, pp. 2014-2020
-
-
Berenholtz, S.M.1
Pronovost, P.J.2
Lipsett, P.A.3
-
33
-
-
2342639544
-
Are antimicrobial-impregnated catheters effective? Don't throw out the baby with the bathwater
-
Crnich CJ, Maki DG. Are antimicrobial-impregnated catheters effective? Don't throw out the baby with the bathwater. Clin Infect Dis 2004; 38:1287-1292
-
(2004)
Clin Infect Dis
, vol.38
, pp. 1287-1292
-
-
Crnich, C.J.1
Maki, D.G.2
-
34
-
-
21244471097
-
Adherence to simple and effective measures reduces the incidence of ventilator-associated pneumonia
-
Baxter AD. Adherence to simple and effective measures reduces the incidence of ventilator-associated pneumonia. Can J Anaesth 2005; 52:535-541
-
(2005)
Can J Anaesth
, vol.52
, pp. 535-541
-
-
Baxter, A.D.1
-
35
-
-
0041329622
-
Effect of standardized orders and provide education on head of bed positioning in mechanically ventilated patients
-
Helman DL. Effect of standardized orders and provide education on head of bed positioning in mechanically ventilated patients. Crit Care Med 2003; 31:2285-2290
-
(2003)
Crit Care Med
, vol.31
, pp. 2285-2290
-
-
Helman, D.L.1
-
36
-
-
33745132106
-
Oral decontamination with chlorhexidine reduces the incidence of ventilator associated pneumonia
-
Koeman M, van der Ven AJ, Hak E, et al. Oral decontamination with chlorhexidine reduces the incidence of ventilator associated pneumonia. Am J Respir Crit Care Med 2006; 173:1348-1355
-
(2006)
Am J Respir Crit Care Med
, vol.173
, pp. 1348-1355
-
-
Koeman, M.1
van der Ven, A.J.2
Hak, E.3
-
37
-
-
3242775982
-
Surviving Sepsis Campaign guidelines for management of severe sepsis and septic shock
-
Dellinger RP, Carlet JM, Masur H, et al. Surviving Sepsis Campaign guidelines for management of severe sepsis and septic shock. Crit Care Med 2004; 32:858-873
-
(2004)
Crit Care Med
, vol.32
, pp. 858-873
-
-
Dellinger, R.P.1
Carlet, J.M.2
Masur, H.3
-
38
-
-
8044246571
-
The effects of ibuprofen on the physiology and survival of patients with sepsis
-
Bernard GR, Wheeler AP, Russell JA, et al. The effects of ibuprofen on the physiology and survival of patients with sepsis. N Engl J Med 1997; 336:912-918
-
(1997)
N Engl J Med
, vol.336
, pp. 912-918
-
-
Bernard, G.R.1
Wheeler, A.P.2
Russell, J.A.3
-
39
-
-
0031762306
-
The benefit of appropriate empirical antibiotic treatment in patients with bloodstream infection
-
Leibovici L, Shraga I, Drucker M, et al. The benefit of appropriate empirical antibiotic treatment in patients with bloodstream infection. J Intern Med 1998; 244:379-386
-
(1998)
J Intern Med
, vol.244
, pp. 379-386
-
-
Leibovici, L.1
Shraga, I.2
Drucker, M.3
-
40
-
-
0032911760
-
Inadequate antimicrobial treatment of infections: A risk factor for hospital mortality among critically ill patients
-
Kollef MH, Shennan G, Ward S, et al. Inadequate antimicrobial treatment of infections: a risk factor for hospital mortality among critically ill patients. Chest 1999; 115:462-474
-
(1999)
Chest
, vol.115
, pp. 462-474
-
-
Kollef, M.H.1
Shennan, G.2
Ward, S.3
-
41
-
-
0242266613
-
Inappropriate initial antimicrobial therapy and its effect on survival in a clinical trial of immunomodulating therapy for severe sepsis
-
Harbarth S, Garbino J, Pugin J, et al. Inappropriate initial antimicrobial therapy and its effect on survival in a clinical trial of immunomodulating therapy for severe sepsis. Am J Med 2003; 115:529-535
-
(2003)
Am J Med
, vol.115
, pp. 529-535
-
-
Harbarth, S.1
Garbino, J.2
Pugin, J.3
-
42
-
-
17044431126
-
The effect of prompt physician visits on intensive care unit mortality and cost
-
Engorgen M. The effect of prompt physician visits on intensive care unit mortality and cost. Crit Care Med 2005; 33:727-732
-
(2005)
Crit Care Med
, vol.33
, pp. 727-732
-
-
Engorgen, M.1
-
43
-
-
12944295224
-
Bloodstream infections caused by antibiotic-resistant Gram-negative bacilli: Risk factors for mortality and impact of inappropriate initial antimicrobial therapy on outcome
-
Lebrovicki, Kang CI, Kim SH, et al. Bloodstream infections caused by antibiotic-resistant Gram-negative bacilli: risk factors for mortality and impact of inappropriate initial antimicrobial therapy on outcome. Antimicrob Agents Chemother 2005; 49:760-766
-
(2005)
Antimicrob Agents Chemother
, vol.49
, pp. 760-766
-
-
Lebrovicki1
Kang, C.I.2
Kim, S.H.3
-
44
-
-
0038468773
-
Outcomes analysis of delayed antibiotic treatment for hospital-acquired Staphylococcus aureus bacteremia
-
Lodise TP, McKinnon PS, Swiderski L, et al. Outcomes analysis of delayed antibiotic treatment for hospital-acquired Staphylococcus aureus bacteremia. Clin Infect Dis 2003; 36:1418-1423
-
(2003)
Clin Infect Dis
, vol.36
, pp. 1418-1423
-
-
Lodise, T.P.1
McKinnon, P.S.2
Swiderski, L.3
-
45
-
-
1642286527
-
Timing of antibiotic administration and outcomes for Medicare patients hospitalized with community-acquired pneumonia
-
Honek PM, Bratzler DW, Nsa W, et al. Timing of antibiotic administration and outcomes for Medicare patients hospitalized with community-acquired pneumonia. Arch Intern Med 2004; 164:637-644
-
(2004)
Arch Intern Med
, vol.164
, pp. 637-644
-
-
Honek, P.M.1
Bratzler, D.W.2
Nsa, W.3
-
46
-
-
0037870468
-
The influence of inadequate empirical antimicrobial treatment on patients with bloodstream infections in an intensive care unit
-
Zaragoza R, Artero A, Camarena JJ, et al. The influence of inadequate empirical antimicrobial treatment on patients with bloodstream infections in an intensive care unit. Clin Microbiol Infect 2003; 9:412-418
-
(2003)
Clin Microbiol Infect
, vol.9
, pp. 412-418
-
-
Zaragoza, R.1
Artero, A.2
Camarena, J.J.3
-
47
-
-
33744527833
-
Duration of hypotension before initiation of effective antimicrobial therapy is the critical determinant of survival in human septic shock
-
Kumar A, Roberts D, Wood KE, et al. Duration of hypotension before initiation of effective antimicrobial therapy is the critical determinant of survival in human septic shock. Crit Care Med 2006; 34:1589-1596
-
(2006)
Crit Care Med
, vol.34
, pp. 1589-1596
-
-
Kumar, A.1
Roberts, D.2
Wood, K.E.3
-
48
-
-
32044436073
-
Optimizing antibiotic treatment for ventilator-associated pneumonia
-
Micek ST, Heuring TJ, Hollands JM, et al. Optimizing antibiotic treatment for ventilator-associated pneumonia. Pharmacotherapy 2006; 26:204-213
-
(2006)
Pharmacotherapy
, vol.26
, pp. 204-213
-
-
Micek, S.T.1
Heuring, T.J.2
Hollands, J.M.3
-
49
-
-
84926232888
-
A comparison of albumin and saline for fluid resuscitation in the intensive care unit
-
The SAFE Study Investigators
-
The SAFE Study Investigators. A comparison of albumin and saline for fluid resuscitation in the intensive care unit. N Engl J Med 2004; 22:2247-2256
-
(2004)
N Engl J Med
, vol.22
, pp. 2247-2256
-
-
-
50
-
-
0028275095
-
Elevation of systemic oxygen delivery in the treatment of critically ill patients
-
Hayes MA, Timmins AC, Yau EH, et al. Elevation of systemic oxygen delivery in the treatment of critically ill patients, N Engl J Med 1994; 330:1717-1722
-
(1994)
N Engl J Med
, vol.330
, pp. 1717-1722
-
-
Hayes, M.A.1
Timmins, A.C.2
Yau, E.H.3
-
51
-
-
0028872009
-
A trial of goal-oriented hemodynamic therapy in critically ill patients
-
Gattinoni L, Brazzi L, Pelosi P, et al. A trial of goal-oriented hemodynamic therapy in critically ill patients. N Engl J Med 1995; 333:1025-1032
-
(1995)
N Engl J Med
, vol.333
, pp. 1025-1032
-
-
Gattinoni, L.1
Brazzi, L.2
Pelosi, P.3
-
52
-
-
0343360868
-
A multicenter, randomized, controlled clinical trial of transfusion requirements in critical care: Transfusion Requirements in Critical Care Investigators, Canadian Critical Care Trials Group
-
Hebert PC, Wells G, Blajchman MA, et al. A multicenter, randomized, controlled clinical trial of transfusion requirements in critical care: Transfusion Requirements in Critical Care Investigators, Canadian Critical Care Trials Group. N Engl J Med 1999; 340:409-417
-
(1999)
N Engl J Med
, vol.340
, pp. 409-417
-
-
Hebert, P.C.1
Wells, G.2
Blajchman, M.A.3
-
53
-
-
23844467420
-
Use of goal-directed therapy for severe sepsis and septic shock in academic emergency departments
-
Jones AE, Kline JA. Use of goal-directed therapy for severe sepsis and septic shock in academic emergency departments Crit Care Med 2005; 33:1888-1889
-
(2005)
Crit Care Med
, vol.33
, pp. 1888-1889
-
-
Jones, A.E.1
Kline, J.A.2
-
54
-
-
33745081608
-
Comparison of two fluid-management strategies in acute lung injury: National Heart, Lung, and Blood Institute Acute Respiratory Distress Syndrome (ARDS) Clinical Trials Network
-
Wiedemann HP, Wheeler AP, Bernard GR, et al. Comparison of two fluid-management strategies in acute lung injury: National Heart, Lung, and Blood Institute Acute Respiratory Distress Syndrome (ARDS) Clinical Trials Network. N Engl J Med 2006; 354:2564-2575
-
(2006)
N Engl J Med
, vol.354
, pp. 2564-2575
-
-
Wiedemann, H.P.1
Wheeler, A.P.2
Bernard, G.R.3
-
55
-
-
33646859471
-
Pulmonary-artery versus central venous catheter to guide treatment of acute lung injury: National Heart, Lung, and Blood Institute Acute Respiratory Distress Syndrome (ARDS) Clinical Trials Network
-
Wheeler AP, Bernard GR, Thompson BT, et al. Pulmonary-artery versus central venous catheter to guide treatment of acute lung injury: National Heart, Lung, and Blood Institute Acute Respiratory Distress Syndrome (ARDS) Clinical Trials Network. N Engl J Med 2006; 354:2213-2224
-
(2006)
N Engl J Med
, vol.354
, pp. 2213-2224
-
-
Wheeler, A.P.1
Bernard, G.R.2
Thompson, B.T.3
-
56
-
-
33745094796
-
Fluid-management strategies in acute lung injury: Liberal, conservative, or both?
-
Rivers EP. Fluid-management strategies in acute lung injury: liberal, conservative, or both? N Engl J Med 2006; 354:2598-2600
-
(2006)
N Engl J Med
, vol.354
, pp. 2598-2600
-
-
Rivers, E.P.1
-
57
-
-
0034882708
-
The use of dopamine in acute renal failure: A meta-analysis
-
Kellum JA, Decker JM. The use of dopamine in acute renal failure: a meta-analysis. Crit Care Med 2001; 29:1526-1531
-
(2001)
Crit Care Med
, vol.29
, pp. 1526-1531
-
-
Kellum, J.A.1
Decker, J.M.2
-
58
-
-
16544389062
-
-
Mullner M, Urbanek B, Havel C, et al. Vasopressors for shock. Cochrane Database Syst Rev (database online). Issue 3, 2004
-
Mullner M, Urbanek B, Havel C, et al. Vasopressors for shock. Cochrane Database Syst Rev (database online). Issue 3, 2004
-
-
-
-
59
-
-
33644584325
-
Does dopamine administration in shock influence outcome? Results of the Sepsis Occurrence in Acutely Ill Patients (SOAP) Study
-
Sakr Y, Reinhart K, Vincent JL, et al. Does dopamine administration in shock influence outcome? Results of the Sepsis Occurrence in Acutely Ill Patients (SOAP) Study. Crit Care Med 2006; 34:589-597
-
(2006)
Crit Care Med
, vol.34
, pp. 589-597
-
-
Sakr, Y.1
Reinhart, K.2
Vincent, J.L.3
-
60
-
-
0035940129
-
The pathogenesis of vasodilatory shock
-
Landry DW, Oliver JA. The pathogenesis of vasodilatory shock. N Engl J Med 2001; 345:588-595
-
(2001)
N Engl J Med
, vol.345
, pp. 588-595
-
-
Landry, D.W.1
Oliver, J.A.2
-
61
-
-
0038663048
-
Arginine vasopressin in advanced vasodilatory shock: A prospective, randomized, controlled study
-
Dunser MW, Mayr AJ, Ulmer H, et al. Arginine vasopressin in advanced vasodilatory shock: a prospective, randomized, controlled study. Circulation 2003; 107:2313-2319
-
(2003)
Circulation
, vol.107
, pp. 2313-2319
-
-
Dunser, M.W.1
Mayr, A.J.2
Ulmer, H.3
-
62
-
-
0343893748
-
-
Acute Respiratory Distress Syndrome Network. Ventilation with low tidal compared with traditional tidal for acute lung injury and the acute respiratory distress syndrome. N Engl J Med 2000; 342:1301-1308
-
Acute Respiratory Distress Syndrome Network. Ventilation with low tidal volumes compared with traditional tidal volumes for acute lung injury and the acute respiratory distress syndrome. N Engl J Med 2000; 342:1301-1308
-
-
-
-
63
-
-
0035880166
-
Efficacy of low tidal volume ventilation in patients with different clinical risk factors for acute lung injury and the acute respiratory distress syndrome
-
Eisner MD, Thompson T, Hudson LD, et al. Efficacy of low tidal volume ventilation in patients with different clinical risk factors for acute lung injury and the acute respiratory distress syndrome. Am J Respir Crit Care Med 2001; 164:231-236
-
(2001)
Am J Respir Crit Care Med
, vol.164
, pp. 231-236
-
-
Eisner, M.D.1
Thompson, T.2
Hudson, L.D.3
-
64
-
-
0034044734
-
Prospective randomized trial comparing pressure-controlled ventilation and volume-controlled ventilation in ARDS: For the Spanish Lung Failure Collaborative Group
-
Esteban A, Alia I, Gordo F, et al. Prospective randomized trial comparing pressure-controlled ventilation and volume-controlled ventilation in ARDS: for the Spanish Lung Failure Collaborative Group. Chest 2000; 117:1690-1696
-
(2000)
Chest
, vol.117
, pp. 1690-1696
-
-
Esteban, A.1
Alia, I.2
Gordo, F.3
-
65
-
-
28944445502
-
-
Acute Respiratory Distress Syndrome Network. Tidal reduction in patients with acute lung injury when plateau pressures are not high. Am J Respir Crit Care Med 2005; 172:1241-1245
-
Acute Respiratory Distress Syndrome Network. Tidal volume reduction in patients with acute lung injury when plateau pressures are not high. Am J Respir Crit Care Med 2005; 172:1241-1245
-
-
-
-
66
-
-
21744435159
-
High tidal volume and positive fluid balance are associated with worse outcome in acute lung injury
-
Sakr Y, Vincent JL, Reinhart K, et al. High tidal volume and positive fluid balance are associated with worse outcome in acute lung injury. Chest 2005; 128:3098-3108
-
(2005)
Chest
, vol.128
, pp. 3098-3108
-
-
Sakr, Y.1
Vincent, J.L.2
Reinhart, K.3
-
67
-
-
4444364798
-
Ventilator-associated lung injury in patients without acute lung injury at the onset of mechanical ventilation
-
Gajic O, Dara SI, Mendez JL, et al. Ventilator-associated lung injury in patients without acute lung injury at the onset of mechanical ventilation. Crit Care Med 2004; 32:1817-1824
-
(2004)
Crit Care Med
, vol.32
, pp. 1817-1824
-
-
Gajic, O.1
Dara, S.I.2
Mendez, J.L.3
-
68
-
-
17044407189
-
Low tidal volume ventilation does not increase sedation use in patients with acute lung injury
-
Kahn JM, Andersson L, Karir V, et al. Low tidal volume ventilation does not increase sedation use in patients with acute lung injury. Crit Care Med 2005; 33:766-771
-
(2005)
Crit Care Med
, vol.33
, pp. 766-771
-
-
Kahn, J.M.1
Andersson, L.2
Karir, V.3
-
69
-
-
0016282065
-
Experimental pulmonary edema due to intermittent positive pressure ventilation with high inflation pressures: Protection by positive end-expiratory pressure
-
Webb HH, Tierney DF. Experimental pulmonary edema due to intermittent positive pressure ventilation with high inflation pressures: protection by positive end-expiratory pressure. Am Rev Respir Dis 1974; 110:556-565
-
(1974)
Am Rev Respir Dis
, vol.110
, pp. 556-565
-
-
Webb, H.H.1
Tierney, D.F.2
-
70
-
-
0030981335
-
Injurious ventilatory strategies increase cytokines and c-fos m-RNA expression in an isolated rat lung model
-
Tremblay L, Valenza F, Ribeiro SP, et al. Injurious ventilatory strategies increase cytokines and c-fos m-RNA expression in an isolated rat lung model. J Clin Invest 1997; 99:944-952
-
(1997)
J Clin Invest
, vol.99
, pp. 944-952
-
-
Tremblay, L.1
Valenza, F.2
Ribeiro, S.P.3
-
71
-
-
3242703034
-
Higher versus lower positive end-expiratory pressures in patients with the acute respiratory distress syndrome
-
Brower RG, Lanken PN, MacIntyre N, et al. Higher versus lower positive end-expiratory pressures in patients with the acute respiratory distress syndrome. N Engl J Med 2004; 351:327-336
-
(2004)
N Engl J Med
, vol.351
, pp. 327-336
-
-
Brower, R.G.1
Lanken, P.N.2
MacIntyre, N.3
-
72
-
-
33646115657
-
Lung recruitment in patients with the acute respiratory distress syndrome
-
Gattinoni L, Caironi P, Cressoni M, et al. Lung recruitment in patients with the acute respiratory distress syndrome. N Engl J Med 2006; 354:1775-1786
-
(2006)
N Engl J Med
, vol.354
, pp. 1775-1786
-
-
Gattinoni, L.1
Caironi, P.2
Cressoni, M.3
-
73
-
-
4344618571
-
Corticosteroids for severe sepsis and septic shock a systematic review and meta-analysis
-
Annane D. Corticosteroids for severe sepsis and septic shock a systematic review and meta-analysis BMJ 2004; 329:480
-
(2004)
BMJ
, vol.329
, pp. 480
-
-
Annane, D.1
-
74
-
-
0037151571
-
Effect of treatment with low doses of hydrocortisone and fludrocortisone on mortality in patients with septic shock
-
Annane D, Sebille V, Charpentier C, et al. Effect of treatment with low doses of hydrocortisone and fludrocortisone on mortality in patients with septic shock. JAMA 2002; 288:862-871
-
(2002)
JAMA
, vol.288
, pp. 862-871
-
-
Annane, D.1
Sebille, V.2
Charpentier, C.3
-
75
-
-
27944488691
-
Relative adrenal insufficiency in patients with septic shock: Comparison of low-dose and conventional corticotropin tests
-
Siraux V, De Backer D, Yalavatti G, et al. Relative adrenal insufficiency in patients with septic shock: comparison of low-dose and conventional corticotropin tests. Crit Care Med 2005; 33:2479-2486
-
(2005)
Crit Care Med
, vol.33
, pp. 2479-2486
-
-
Siraux, V.1
De Backer, D.2
Yalavatti, G.3
-
76
-
-
3042762336
-
Measurements of serum free cortisol in critically ill patients
-
Hamrahian AH, Tawakalitu SO, Arafah BM. Measurements of serum free cortisol in critically ill patients. N Engl J Med 2004; 350:1629-1638
-
(2004)
N Engl J Med
, vol.350
, pp. 1629-1638
-
-
Hamrahian, A.H.1
Tawakalitu, S.O.2
Arafah, B.M.3
-
77
-
-
33747600895
-
Steroid use in PROWESS severe sepsis patients treated with drotrecogin alfa (activated)
-
Levy H, Laterre PF, Bates B, et al. Steroid use in PROWESS severe sepsis patients treated with drotrecogin alfa (activated). Crit Care 2005; 9:R502-R507
-
(2005)
Crit Care
, vol.9
-
-
Levy, H.1
Laterre, P.F.2
Bates, B.3
-
78
-
-
3042858950
-
Meta-analysis: The effect of steroids on survival and shock during sepsis depends on the dose
-
Minneci PC, Deans KJ, Banks SM, et al. Meta-analysis: the effect of steroids on survival and shock during sepsis depends on the dose. Ann Intern Med 2004; 141:47-56
-
(2004)
Ann Intern Med
, vol.141
, pp. 47-56
-
-
Minneci, P.C.1
Deans, K.J.2
Banks, S.M.3
-
79
-
-
0041942666
-
Clinical equipoise remains for issues of adrenocorticotropic hormone administration, cortisol testing, and therapeutic use of hydrocortisone
-
Annane D, Briegel J, Keh D, et al. Clinical equipoise remains for issues of adrenocorticotropic hormone administration, cortisol testing, and therapeutic use of hydrocortisone. Crit Care Med 2003; 31:2250-2251
-
(2003)
Crit Care Med
, vol.31
, pp. 2250-2251
-
-
Annane, D.1
Briegel, J.2
Keh, D.3
-
80
-
-
0345374590
-
Association between hyperglycemia and increased hospital mortality in a heterogeneous population of critically ill patients
-
Krinsley JS. Association between hyperglycemia and increased hospital mortality in a heterogeneous population of critically ill patients. Mayo Clin Proc 2003; 78:1471-1478
-
(2003)
Mayo Clin Proc
, vol.78
, pp. 1471-1478
-
-
Krinsley, J.S.1
-
81
-
-
0035829852
-
Intensive insulin therapy in the critically ill patients
-
van den Berghe G, Wouters P, Weekers F, et al. Intensive insulin therapy in the critically ill patients. N Engl J Med 2001; 345:1359-1367
-
(2001)
N Engl J Med
, vol.345
, pp. 1359-1367
-
-
van den Berghe, G.1
Wouters, P.2
Weekers, F.3
-
83
-
-
0142088505
-
Glucose control and mortality in critically ill patients
-
Finney SJ, Zekveld C, Elia A, et al. Glucose control and mortality in critically ill patients. JAMA 2003; 290:2041-2047
-
(2003)
JAMA
, vol.290
, pp. 2041-2047
-
-
Finney, S.J.1
Zekveld, C.2
Elia, A.3
-
84
-
-
0037326620
-
Outcome benefit of intensive insulin therapy in the critically ill: Insulin dose versus glycemic control
-
Van den Berghe G, Wouters R, Weekers F, et al. Outcome benefit of intensive insulin therapy in the critically ill: insulin dose versus glycemic control. Crit Care Med 2003; 31:359-366
-
(2003)
Crit Care Med
, vol.31
, pp. 359-366
-
-
Van den Berghe, G.1
Wouters, R.2
Weekers, F.3
-
85
-
-
0035826096
-
Efficacy and safety of recombinant human activated protein C for severe sepsis
-
Bernard GR, Vincent JL, Laterre PF, et al. Efficacy and safety of recombinant human activated protein C for severe sepsis. N Engl J Med 2001; 344:699-709
-
(2001)
N Engl J Med
, vol.344
, pp. 699-709
-
-
Bernard, G.R.1
Vincent, J.L.2
Laterre, P.F.3
-
86
-
-
8544268686
-
The effect of drotrecogin alfa (activated) on long-term survival after severe sepsis
-
Angus DC, Laterre PF, Helterbrand J, et al. The effect of drotrecogin alfa (activated) on long-term survival after severe sepsis. Crit Care Med 2004; 32:2199-2206
-
(2004)
Crit Care Med
, vol.32
, pp. 2199-2206
-
-
Angus, D.C.1
Laterre, P.F.2
Helterbrand, J.3
-
87
-
-
0037352375
-
Effects of Drotrecogin alfa activated on organ dysfunction in the prowess trial
-
Vincent JL, Angus DC, Artigas A, et al. Effects of Drotrecogin alfa activated on organ dysfunction in the prowess trial. Crit Care Med 2003; 31:834-840
-
(2003)
Crit Care Med
, vol.31
, pp. 834-840
-
-
Vincent, J.L.1
Angus, D.C.2
Artigas, A.3
-
88
-
-
25444492831
-
Drotrecogin alfa (activated) for adults with severe sepsis and a low risk of death
-
Abraham E, Laterre PF, Garg R, et al. Drotrecogin alfa (activated) for adults with severe sepsis and a low risk of death. N Engl J Med 2005; 353:1332-1341
-
(2005)
N Engl J Med
, vol.353
, pp. 1332-1341
-
-
Abraham, E.1
Laterre, P.F.2
Garg, R.3
-
90
-
-
26444604781
-
Drotrecogin alfa (Activated) treatment in severe sepsis form the global open-label trial ENHANCE: Further evidence for survival and safety and implications for early treatment
-
Vincent J-L, Light B, Wright T, et al. Drotrecogin alfa (Activated) treatment in severe sepsis form the global open-label trial ENHANCE: further evidence for survival and safety and implications for early treatment. Crit Care Med 2005; 33:2266-2277
-
(2005)
Crit Care Med
, vol.33
, pp. 2266-2277
-
-
Vincent, J.-L.1
Light, B.2
Wright, T.3
-
91
-
-
34247550973
-
Use of an integrated clinical trial database to evaluate the effect of timing of Drotrecogin alfa (activated) treatment in severe sepsis
-
Vincent J-L, O'Brien J Jr, Wheeler A, et al. Use of an integrated clinical trial database to evaluate the effect of timing of Drotrecogin alfa (activated) treatment in severe sepsis. Crit Care 2006; 10:R74
-
(2006)
Crit Care
, vol.10
-
-
Vincent, J.-L.1
O'Brien Jr, J.2
Wheeler, A.3
-
92
-
-
2942550860
-
Drotrecogin alfa (activated): A pharmacoeconomic review of its use in severe sepsis
-
Frampton JE, Foster RH. Drotrecogin alfa (activated): a pharmacoeconomic review of its use in severe sepsis. Pharmacoeconomics 2004; 22:445-476
-
(2004)
Pharmacoeconomics
, vol.22
, pp. 445-476
-
-
Frampton, J.E.1
Foster, R.H.2
-
93
-
-
0037253093
-
Cost-effectiveness of drotrecogin alfa (activated) in the treatment of severe sepsis
-
Angus DC, Linde-Zwirble WT, Clermont G, et al. Cost-effectiveness of drotrecogin alfa (activated) in the treatment of severe sepsis. Crit Care Med 2003; 1:1-11
-
(2003)
Crit Care Med
, vol.1
, pp. 1-11
-
-
Angus, D.C.1
Linde-Zwirble, W.T.2
Clermont, G.3
-
94
-
-
33645805899
-
Implementation and outcomes of the Multiple Urgent Sepsis Therapies (MUST) protocol
-
Shapiro NI, Howell MD, Talmor D, et al. Implementation and outcomes of the Multiple Urgent Sepsis Therapies (MUST) protocol. Crit Care Med 2006; 34:1025-1032
-
(2006)
Crit Care Med
, vol.34
, pp. 1025-1032
-
-
Shapiro, N.I.1
Howell, M.D.2
Talmor, D.3
-
95
-
-
33344468985
-
Translating research to clinical practice: A 1-year experience with implementing early goal-directed therapy for septic shock in the emergency department
-
Trzeciak S, Dellinger RP, Abate NL, et al. Translating research to clinical practice: a 1-year experience with implementing early goal-directed therapy for septic shock in the emergency department. Chest 2006; 129:225-232
-
(2006)
Chest
, vol.129
, pp. 225-232
-
-
Trzeciak, S.1
Dellinger, R.P.2
Abate, N.L.3
-
96
-
-
19844370909
-
A multidisciplinary community hospital program for early and rapid resuscitation of shock in nontrauma patients
-
Sebat F, Johnson D, Musthafa AA, et al. A multidisciplinary community hospital program for early and rapid resuscitation of shock in nontrauma patients. Chest 2005; 127:1729-1743
-
(2005)
Chest
, vol.127
, pp. 1729-1743
-
-
Sebat, F.1
Johnson, D.2
Musthafa, A.A.3
-
97
-
-
33645076841
-
Implementation of an evidence-based "standard operating procedure" and outcome in septic shock
-
Kortgen A, Niederprum P, Bauer M. Implementation of an evidence-based "standard operating procedure" and outcome in septic shock. Crit Care Med 2006; 34:943-949
-
(2006)
Crit Care Med
, vol.34
, pp. 943-949
-
-
Kortgen, A.1
Niederprum, P.2
Bauer, M.3
-
98
-
-
31744438366
-
The impact of compliance with 6-hour and 24-hour sepsis bundles on hospital mortality in patients with severe sepsis: A prospective observational study
-
Gao F, Melody T, Daniels DF, et al. The impact of compliance with 6-hour and 24-hour sepsis bundles on hospital mortality in patients with severe sepsis: a prospective observational study. Crit Care 2005; 9:R764-R770
-
(2005)
Crit Care
, vol.9
-
-
Gao, F.1
Melody, T.2
Daniels, D.F.3
|