Evaluation of the effects of serial phlebotomy on the transcriptome of major tissues and on the response to toxicants in rats

Toxicology Letters

Volumn 176, Issue 2, 2008, Pages 138-148

  Blomme, Eric A G ^a   Ciurlionis, Rita ^a   Marsh, Kennan C ^a   Waring, Jeffrey F ^a   Yang, Yi ^a  

^a ABBOTT LABORATORIES   (United States)

Author keywords

Bleeding; Pharmacokinetic; Toxicogenomics; Transcriptome

Indexed keywords

AZITHROMYCIN; BACITRACIN; CALCITRIOL; CARMUSTINE; CERIVASTATIN; CISPLATIN; CLOTRIMAZOLE; CYCLOSPORIN; DAUNORUBICIN; DIETHYLNITROSAMINE; DIMETHYLNITROSAMINE; DOXORUBICIN; EPIRUBICIN; ETOPOSIDE; FINASTERIDE; FLAVOXATE; IDARUBICIN; IFOSFAMIDE; INDOMETACIN; KETOCONAZOLE; LEAD ACETATE; LEFLUNOMIDE; N,N DIMETHYLFORMAMIDE; NEVIRAPINE; NIMESULIDE; ROFLUMILAST; TIOGUANINE; TRANSCRIPTOME; UNINDEXED DRUG; VALPROIC ACID;

ANIMAL EXPERIMENT; ANIMAL TISSUE; ARTICLE; CONTROLLED STUDY; DRUG EFFECT; FATTY ACID OXIDATION; GENE EXPRESSION PROFILING; HISTOPATHOLOGY; HOMEOSTASIS; KIDNEY PARENCHYMA; LIVER; MALE; NONHUMAN; PHLEBOTOMY; PRIORITY JOURNAL; RAT; SINGLE DRUG DOSE; SPLEEN; TOXICITY TESTING; TOXICOKINETICS;

ANIMALS; BLOOD PROTEINS; CISPLATIN; DOXORUBICIN; ERYTHROCYTE COUNT; GENE EXPRESSION; GENE EXPRESSION PROFILING; HEART; HEMATOCRIT; HEMOGLOBINS; INJECTIONS, INTRAVENOUS; KIDNEY; KIDNEY TUBULES, PROXIMAL; LEUKOCYTE COUNT; LIVER; MALE; MYOCARDIUM; PATHOLOGY, CLINICAL; PHLEBOTOMY; RATS; RATS, SPRAGUE-DAWLEY; REGRESSION ANALYSIS; SPLEEN;

RATTUS;

EID: 37549018979     PISSN: 03784274     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.toxlet.2007.09.014     Document Type: Article

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