Expression of serine/threonine protein-kinases and related factors in normal monkey and human retinas: The mechanistic understanding of a CDK2 inhibitor induced retinal toxicity

Toxicologic Pathology

Volumn 35, Issue 7, 2007, Pages 972-983

  Saturno, Grazia ^a,c   Pesenti, Manuela ^a   Cavazzoli, Cristiano ^a   Rossi, Anna ^a,d   Giusti, Anna M ^a   Gierke, Berthold ^b   Pawlak, Michael ^b   Venturi, Miro ^a  

^a NERVIANO MEDICAL SCIENCES   (Italy)

^b UNIVERSITY OF TÜBINGEN   (Germany)

^c INSTITUTE OF CANCER RESEARCH   (United Kingdom)

^d NV ORGANON   (Netherlands)

Author keywords

Cyclin dependent kinases; Kinase inhibitors; LCM; Protein array; Retinal toxicity

Indexed keywords

CYCLIN DEPENDENT KINASE; CYCLIN DEPENDENT KINASE 1; CYCLIN DEPENDENT KINASE 2; CYCLIN DEPENDENT KINASE 2 INHIBITOR; CYCLIN DEPENDENT KINASE 4; CYCLIN DEPENDENT KINASE 5; GLYCOGEN SYNTHASE KINASE 3BETA; MICROTUBULE ASSOCIATED PROTEIN; PROTEIN SERINE THREONINE KINASE; TAU PROTEIN;

ANIMAL TISSUE; ARTICLE; CELL DAMAGE; CONTROLLED STUDY; DRUG ACTIVITY; EYE TOXICITY; FEMALE; GENE EXPRESSION; HISTOPATHOLOGY; HUMAN; HUMAN TISSUE; IMMUNOFLUORESCENCE; IMMUNOHISTOCHEMISTRY; LASER CAPTURE MICRODISSECTION; MALE; MONKEY; NONHUMAN; NUCLEOTIDE SEQUENCE; PHOTORECEPTOR; PRIORITY JOURNAL; PROTEIN EXPRESSION; PROTEIN MICROARRAY; REAL TIME POLYMERASE CHAIN REACTION; RETINA; RETINA CONE; RETINA ROD; RISK ASSESSMENT;

ANIMALS; CYCLIN-DEPENDENT KINASE 2; FEMALE; FLUORESCENT ANTIBODY TECHNIQUE; GLYCOGEN SYNTHASE KINASE 3; HUMANS; IMMUNOHISTOCHEMISTRY; MACACA FASCICULARIS; MALE; MICRODISSECTION; PHOSPHORYLATION; POLYMERASE CHAIN REACTION; PROTEIN KINASE INHIBITORS; PROTEIN-SERINE-THREONINE KINASES; RETINA; TAU PROTEINS;

EID: 37549000240     PISSN: 01926233     EISSN: 15331601     Source Type: Journal    
DOI: 10.1080/01926230701748271     Document Type: Article

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