메뉴 건너뛰기




Volumn 83, Issue 9-10, 2007, Pages 277-295

Hormonal control by A-factor of morphological development and secondary metabolism in Streptomyces

Author keywords

A factor; A factor receptor; Morphological differentiation; Secondary metabolism; Streptomyces; Streptomycin biosynthesis

Indexed keywords

BACTERIA (MICROORGANISMS); FUNGI; STREPTOMYCES; STREPTOMYCES GRISEUS;

EID: 37548998935     PISSN: 03862208     EISSN: 13492896     Source Type: Journal    
DOI: 10.2183/pjab.83.277     Document Type: Review
Times cited : (87)

References (65)
  • 1
    • 0032879027 scopus 로고    scopus 로고
    • Forty years of genetics with Streptomyces: From in vivo through in vitro to in silico
    • Hopwood, D. A. (1999) Forty years of genetics with Streptomyces: from in vivo through in vitro to in silico. Microbiology 145, 2183-2202.
    • (1999) Microbiology , vol.145 , pp. 2183-2202
    • Hopwood, D.A.1
  • 2
    • 0028245937 scopus 로고
    • A-factor as a microbial hormone that controls cellular differentiation and secondary metabolism in Streptomyces griseus
    • Horinouchi, S. and Beppu, T. (1994) A-factor as a microbial hormone that controls cellular differentiation and secondary metabolism in Streptomyces griseus. Mol. Microbiol. 12, 859-864.
    • (1994) Mol. Microbiol , vol.12 , pp. 859-864
    • Horinouchi, S.1    Beppu, T.2
  • 3
    • 17844392892 scopus 로고    scopus 로고
    • AdpA, a central transcriptional regulator in the A-factor regulatory cascade that leads to morphological development and secondary metabolism in Streptomyces griseus
    • Ohnishi, Y., Yamazaki, H., Kato, J., Tomono, A. and Horinouchi, S. (2005) AdpA, a central transcriptional regulator in the A-factor regulatory cascade that leads to morphological development and secondary metabolism in Streptomyces griseus. Biosci. Biotechnol. Biochem. 69, 431-439.
    • (2005) Biosci. Biotechnol. Biochem , vol.69 , pp. 431-439
    • Ohnishi, Y.1    Yamazaki, H.2    Kato, J.3    Tomono, A.4    Horinouchi, S.5
  • 4
    • 33847408410 scopus 로고    scopus 로고
    • Mining and polishing of the treasure trove in the bacterial genus Streptomyces
    • Horinouchi, S. (2007) Mining and polishing of the treasure trove in the bacterial genus Streptomyces. Biosci. Biotechnol. Biochem. 71, 283-299.
    • (2007) Biosci. Biotechnol. Biochem , vol.71 , pp. 283-299
    • Horinouchi, S.1
  • 6
    • 0019997456 scopus 로고
    • Mutants blocked in streptomycin production in Streptomyces griseus - the role of A-factor
    • Hara, O. and Beppu, T. (1982) Mutants blocked in streptomycin production in Streptomyces griseus - the role of A-factor. J. Antibiot. 35, 349-358.
    • (1982) J. Antibiot , vol.35 , pp. 349-358
    • Hara, O.1    Beppu, T.2
  • 7
    • 0027957161 scopus 로고
    • Quorum sensing in bacteria: The LuxR-LuxI family of cell density-responsive transcriptional regulators
    • Fuqua, W. C., Winans, S. C. and Greenberg, E. P. (1994) Quorum sensing in bacteria: the LuxR-LuxI family of cell density-responsive transcriptional regulators. J. Bacteriol. 176, 269-275.
    • (1994) J. Bacteriol , vol.176 , pp. 269-275
    • Fuqua, W.C.1    Winans, S.C.2    Greenberg, E.P.3
  • 8
    • 27944442272 scopus 로고    scopus 로고
    • Quorum sensing: Cell-to-cell communication in bacteria
    • Waters, C. M. and Bassler, B. L. (2005) Quorum sensing: cell-to-cell communication in bacteria. Annu. Rev. Cell Dev. Biol. 21, 319-346.
    • (2005) Annu. Rev. Cell Dev. Biol , vol.21 , pp. 319-346
    • Waters, C.M.1    Bassler, B.L.2
  • 9
    • 1842853982 scopus 로고    scopus 로고
    • Structures of grixazone A and B, A-factor-dependent yellow pigments produced under phosphate depletion by Streptomyces griseus
    • Ohnishi, Y., Furusho, Y., Higashi, T., Chun, H.-K., Furihata, K., Sakuda, S. and Horinouchi, S. (2004) Structures of grixazone A and B, A-factor-dependent yellow pigments produced under phosphate depletion by Streptomyces griseus. J. Antibiot. 57, 218-223.
    • (2004) J. Antibiot , vol.57 , pp. 218-223
    • Ohnishi, Y.1    Furusho, Y.2    Higashi, T.3    Chun, H.-K.4    Furihata, K.5    Sakuda, S.6    Horinouchi, S.7
  • 12
    • 28044436696 scopus 로고    scopus 로고
    • Biosynthesis of hexahydroxyperylenequinone melanin via oxidative aryl coupling by cytochrome P-450 in Streptomyces griseus
    • Funa, N., Funabashi, M., Ohnishi, Y. and Horinouchi, S. (2005) Biosynthesis of hexahydroxyperylenequinone melanin via oxidative aryl coupling by cytochrome P-450 in Streptomyces griseus. J. Bacteriol. 187, 8149-8155.
    • (2005) J. Bacteriol , vol.187 , pp. 8149-8155
    • Funa, N.1    Funabashi, M.2    Ohnishi, Y.3    Horinouchi, S.4
  • 13
    • 0028834241 scopus 로고
    • Cloning and characterization of the A-factor receptor gene from Streptomyces griseus
    • Onaka, H., Ando, N., Nihira, T., Yamada, Y., Beppu, T. and Horinouchi, S. (1995) Cloning and characterization of the A-factor receptor gene from Streptomyces griseus. J. Bacteriol. 177, 6083-6092.
    • (1995) J. Bacteriol , vol.177 , pp. 6083-6092
    • Onaka, H.1    Ando, N.2    Nihira, T.3    Yamada, Y.4    Beppu, T.5    Horinouchi, S.6
  • 14
    • 0030774268 scopus 로고    scopus 로고
    • Butyrolactone autoregulator receptor protein (BarA) as a transcriptional regulator in Streptomyces virginiae
    • Kinoshita, H., Ipposhi, H., Okamoto, S., Nakano, H., Nihira, T. and Yamada, Y. (1997) Butyrolactone autoregulator receptor protein (BarA) as a transcriptional regulator in Streptomyces virginiae. J. Bacteriol. 179, 6986-6993.
    • (1997) J. Bacteriol , vol.179 , pp. 6986-6993
    • Kinoshita, H.1    Ipposhi, H.2    Okamoto, S.3    Nakano, H.4    Nihira, T.5    Yamada, Y.6
  • 15
    • 0030857513 scopus 로고    scopus 로고
    • Cloning and characterization of the gene (farA) encoding the receptor for an extracellular regulatory factor (IM-2) from Streptomyces sp. strain FRI-5
    • Waki, M., Nihira, T. and Yamada, Y. (1997) Cloning and characterization of the gene (farA) encoding the receptor for an extracellular regulatory factor (IM-2) from Streptomyces sp. strain FRI-5. J. Bacteriol. 179, 5131-5137.
    • (1997) J. Bacteriol , vol.179 , pp. 5131-5137
    • Waki, M.1    Nihira, T.2    Yamada, Y.3
  • 16
    • 0020546194 scopus 로고
    • Genetic analysis of A-factor synthesis in Streptomyces coelicolor A3(2) and Streptomyces griseus
    • Hara, O., Horinouchi, S., Uozumi, T. and Beppu, T. (1983) Genetic analysis of A-factor synthesis in Streptomyces coelicolor A3(2) and Streptomyces griseus. J. Gen. Microbiol. 129, 2939-2944.
    • (1983) J. Gen. Microbiol , vol.129 , pp. 2939-2944
    • Hara, O.1    Horinouchi, S.2    Uozumi, T.3    Beppu, T.4
  • 17
    • 0021324641 scopus 로고
    • Unstable genetic determinant of A-factor biosynthesis in streptomycin-producing organisms: Cloning and characterization
    • Horinouchi, S., Kumada, Y. and Beppu, T. (1984) Unstable genetic determinant of A-factor biosynthesis in streptomycin-producing organisms: cloning and characterization. J. Bacteriol. 158, 481-487.
    • (1984) J. Bacteriol , vol.158 , pp. 481-487
    • Horinouchi, S.1    Kumada, Y.2    Beppu, T.3
  • 18
    • 0024546628 scopus 로고
    • Nucleotide sequence and transcriptional analysis of the Streptomyces griseus gene (afsA) responsible for A-factor biosynthesis
    • Horinouchi, S., Suzuki, H., Nishiyama, M. and Beppu, T. (1989) Nucleotide sequence and transcriptional analysis of the Streptomyces griseus gene (afsA) responsible for A-factor biosynthesis. J. Bacteriol. 171, 1206-1210.
    • (1989) J. Bacteriol , vol.171 , pp. 1206-1210
    • Horinouchi, S.1    Suzuki, H.2    Nishiyama, M.3    Beppu, T.4
  • 19
    • 0030726879 scopus 로고    scopus 로고
    • Involvement of AfsA in A-factor biosynthesis as a key enzyme
    • Ando, N., Matsumori, N., Sakuda, S., Beppu, T. and Horinouchi, S. (1997) Involvement of AfsA in A-factor biosynthesis as a key enzyme. J. Antibiot. 50, 847-852.
    • (1997) J. Antibiot , vol.50 , pp. 847-852
    • Ando, N.1    Matsumori, N.2    Sakuda, S.3    Beppu, T.4    Horinouchi, S.5
  • 22
    • 33847407962 scopus 로고    scopus 로고
    • Biosynthesis of γ-butyrolactone autoregulators that switch on secondary metabolism and morphological development in Streptomyces
    • Kato, J., Funa, N., Watanabe, H., Ohnishi, Y. and Horinouchi, S. (2007) Biosynthesis of γ-butyrolactone autoregulators that switch on secondary metabolism and morphological development in Streptomyces. Proc. Natl. Acad. Sci. USA 104, 2378-2383.
    • (2007) Proc. Natl. Acad. Sci. USA , vol.104 , pp. 2378-2383
    • Kato, J.1    Funa, N.2    Watanabe, H.3    Ohnishi, Y.4    Horinouchi, S.5
  • 23
    • 37049085996 scopus 로고
    • Biosynthetic studies on virginiae butanolide A, a butyrolactone autoregulator from Streptomyces. Part 2. Preparation of possible biosynthetic intermediates and conversion experiments in a cell-free system
    • Sakuda, S., Tanaka, S., Mizuno, K., Sukcharoen, O., Nihira, T. and Yamada, Y. (1993) Biosynthetic studies on virginiae butanolide A, a butyrolactone autoregulator from Streptomyces. Part 2. Preparation of possible biosynthetic intermediates and conversion experiments in a cell-free system. J. Chem. Soc. Perkin Trans. 1, 1993, 2309-2315.
    • (1993) J. Chem. Soc. Perkin Trans. 1 , vol.1993 , pp. 2309-2315
    • Sakuda, S.1    Tanaka, S.2    Mizuno, K.3    Sukcharoen, O.4    Nihira, T.5    Yamada, Y.6
  • 24
    • 10644295401 scopus 로고    scopus 로고
    • Kimber, M. S., Martin, F., Lu, Y., Houston, S., Vedadi, M., Dharamsi, A., Fiebig, K. M., Schmid, M. and Rock, C. O. (2004) The structure of (3R)-hydroxyacyl-acyl carrier protein dehydratase (FabZ) from Pseudomonas aeruginosa. J. Biol. Chem. 279, 52593-52602.
    • Kimber, M. S., Martin, F., Lu, Y., Houston, S., Vedadi, M., Dharamsi, A., Fiebig, K. M., Schmid, M. and Rock, C. O. (2004) The structure of (3R)-hydroxyacyl-acyl carrier protein dehydratase (FabZ) from Pseudomonas aeruginosa. J. Biol. Chem. 279, 52593-52602.
  • 25
    • 33744552662 scopus 로고    scopus 로고
    • γ-Butyrolactones: Streptomyces signaling molecules regulating antibiotic production and differentiation
    • Takano, E. (2006) γ-Butyrolactones: Streptomyces signaling molecules regulating antibiotic production and differentiation. Curr. Opin. Microbiol. 9, 287-294.
    • (2006) Curr. Opin. Microbiol , vol.9 , pp. 287-294
    • Takano, E.1
  • 26
    • 0036724816 scopus 로고    scopus 로고
    • barS1, a gene for biosynthesis of a γ-butyrolactone autoregulator, a microbial signaling molecule eliciting antibiotic production in Streptomyces species
    • Shikura, N., Yamamura, J. and Nihira, T. (2002) barS1, a gene for biosynthesis of a γ-butyrolactone autoregulator, a microbial signaling molecule eliciting antibiotic production in Streptomyces species. J. Bacteriol. 184, 5151-5157.
    • (2002) J. Bacteriol , vol.184 , pp. 5151-5157
    • Shikura, N.1    Yamamura, J.2    Nihira, T.3
  • 27
    • 0030756415 scopus 로고    scopus 로고
    • A Streptomyces griseus gene (sgaA) suppresses the growth disturbance caused by high osmolality and a high concentration of A-factor during early growth
    • Ando, N., Ueda, K. and Horinouchi, S. (1997) A Streptomyces griseus gene (sgaA) suppresses the growth disturbance caused by high osmolality and a high concentration of A-factor during early growth. Microbiology 143, 2715-2723.
    • (1997) Microbiology , vol.143 , pp. 2715-2723
    • Ando, N.1    Ueda, K.2    Horinouchi, S.3
  • 28
    • 1642367161 scopus 로고    scopus 로고
    • A single target is sufficient to account for the biological effects of the A-factor receptor protein of Streptomyces griseus
    • Kato, J., Miyahisa, I., Mashiko, M., Ohnishi, Y. and Horinouchi, S. (2004) A single target is sufficient to account for the biological effects of the A-factor receptor protein of Streptomyces griseus. J. Bacteriol. 186, 2206-2211.
    • (2004) J. Bacteriol , vol.186 , pp. 2206-2211
    • Kato, J.1    Miyahisa, I.2    Mashiko, M.3    Ohnishi, Y.4    Horinouchi, S.5
  • 29
    • 0031779298 scopus 로고    scopus 로고
    • Gene replacement analysis of the Streptomyces virginiae barA gene encoding the butyrolactone autoregulator receptor reveals that BarA acts as a repressor in virginiamycin biosynthesis
    • Nakano, H., Takehara, E., Nihira, T. and Yamada, Y. (1998) Gene replacement analysis of the Streptomyces virginiae barA gene encoding the butyrolactone autoregulator receptor reveals that BarA acts as a repressor in virginiamycin biosynthesis. J. Bacteriol. 180, 3317-3322.
    • (1998) J. Bacteriol , vol.180 , pp. 3317-3322
    • Nakano, H.1    Takehara, E.2    Nihira, T.3    Yamada, Y.4
  • 31
    • 0025353043 scopus 로고
    • The A-factor-binding protein of Streptomyces griseus negatively controls streptomycin production and sporulation
    • Miyake, K., Kuzuyama, T., Horinouchi, S. and Beppu, T. (1990) The A-factor-binding protein of Streptomyces griseus negatively controls streptomycin production and sporulation. J. Bacteriol. 172, 3003-3008.
    • (1990) J. Bacteriol , vol.172 , pp. 3003-3008
    • Miyake, K.1    Kuzuyama, T.2    Horinouchi, S.3    Beppu, T.4
  • 32
    • 0030836620 scopus 로고    scopus 로고
    • DNA-binding activity of the A-factor receptor protein and its recognition DNA sequences
    • Onaka, H. and Horinouchi, S. (1997) DNA-binding activity of the A-factor receptor protein and its recognition DNA sequences. Mol. Microbiol. 24, 991-1000.
    • (1997) Mol. Microbiol , vol.24 , pp. 991-1000
    • Onaka, H.1    Horinouchi, S.2
  • 33
    • 0032487744 scopus 로고    scopus 로고
    • Site-directed mutagenesis of the A-factor receptor protein: Val-41 important for DNA-binding and Trp-119 important for ligand-binding
    • Sugiyama, M., Onaka, H., Nakagawa, T. and Horinouchi, S. (1998) Site-directed mutagenesis of the A-factor receptor protein: Val-41 important for DNA-binding and Trp-119 important for ligand-binding. Gene 222, 133-144.
    • (1998) Gene , vol.222 , pp. 133-144
    • Sugiyama, M.1    Onaka, H.2    Nakagawa, T.3    Horinouchi, S.4
  • 34
    • 0030970074 scopus 로고    scopus 로고
    • A mutation at proline-115 in the A-factor receptor protein of Streptomyces griseus abolishes DNA-binding ability but not ligand-binding ability
    • Onaka, H., Sugiyama, M. and Horinouchi, S. (1997) A mutation at proline-115 in the A-factor receptor protein of Streptomyces griseus abolishes DNA-binding ability but not ligand-binding ability. J. Bacteriol. 179, 2748-2752.
    • (1997) J. Bacteriol , vol.179 , pp. 2748-2752
    • Onaka, H.1    Sugiyama, M.2    Horinouchi, S.3
  • 35
    • 0031859952 scopus 로고    scopus 로고
    • Involvement of two A-factor receptor homologues in Streptomyces coelicolor A3(2) in the regulation of secondary metabolism and morphogenesis
    • Onaka, H., Nakagawa, T. and Horinouchi, S. (1998) Involvement of two A-factor receptor homologues in Streptomyces coelicolor A3(2) in the regulation of secondary metabolism and morphogenesis. Mol. Microbiol. 28, 743-753.
    • (1998) Mol. Microbiol , vol.28 , pp. 743-753
    • Onaka, H.1    Nakagawa, T.2    Horinouchi, S.3
  • 36
    • 0742324526 scopus 로고    scopus 로고
    • Crystal structure of a γ-butyrolactone autoregulator receptor protein in Streptomyces coelicolor A3(2)
    • Natsume, R., Ohnishi, Y., Senda, T. and Horinouchi, S. (2004) Crystal structure of a γ-butyrolactone autoregulator receptor protein in Streptomyces coelicolor A3(2). J. Mol. Biol. 336, 409-419.
    • (2004) J. Mol. Biol , vol.336 , pp. 409-419
    • Natsume, R.1    Ohnishi, Y.2    Senda, T.3    Horinouchi, S.4
  • 37
    • 0036500260 scopus 로고    scopus 로고
    • Structural basis for cooperative DNA binding by two dimers of the multidrug-binding protein
    • Schumacher, M. A., Miller, M. C., Grkovic, S., Brown, M. H., Skurray, R. A. and Brennan, R. G. (2002) Structural basis for cooperative DNA binding by two dimers of the multidrug-binding protein. EMBO J. 21, 1210-1218.
    • (2002) EMBO J , vol.21 , pp. 1210-1218
    • Schumacher, M.A.1    Miller, M.C.2    Grkovic, S.3    Brown, M.H.4    Skurray, R.A.5    Brennan, R.G.6
  • 38
    • 0034087676 scopus 로고    scopus 로고
    • Structural basis of gene regulation by the tetracycline inducible Tet repressor-operator system
    • Orth, P., Schnappinger, D., Hillen, W., Saenger, W. and Hinrichs, W. (2000) Structural basis of gene regulation by the tetracycline inducible Tet repressor-operator system. Nat. Struct. Biol. 7, 215-219.
    • (2000) Nat. Struct. Biol , vol.7 , pp. 215-219
    • Orth, P.1    Schnappinger, D.2    Hillen, W.3    Saenger, W.4    Hinrichs, W.5
  • 40
    • 0026656737 scopus 로고
    • Streptomycin biosynthesis and its regulation in streptomycetes
    • Distler, J., Mansouri, K., Mayer, G., Stockmann, M. and Piepersberg, W. (1992) Streptomycin biosynthesis and its regulation in streptomycetes. Gene 115, 105-111.
    • (1992) Gene , vol.115 , pp. 105-111
    • Distler, J.1    Mansouri, K.2    Mayer, G.3    Stockmann, M.4    Piepersberg, W.5
  • 41
    • 23644431543 scopus 로고    scopus 로고
    • Transcriptional control by A-factor of strR, the pathway-specific transcriptional activator for streptomycin biosynthesis in Streptomyces griseus
    • Tomono, A., Tsai, Y., Yamazaki, H., Ohnishi, Y. and Horinouchi, S. (2005) Transcriptional control by A-factor of strR, the pathway-specific transcriptional activator for streptomycin biosynthesis in Streptomyces griseus. J. Bacteriol. 187, 5595-5604.
    • (2005) J. Bacteriol , vol.187 , pp. 5595-5604
    • Tomono, A.1    Tsai, Y.2    Yamazaki, H.3    Ohnishi, Y.4    Horinouchi, S.5
  • 42
    • 0025861807 scopus 로고
    • Identification of an A-factor-dependent promoter in the streptomycin biosynthetic gene cluster of Streptomyces griseus
    • Vujaklija, D., Ueda, K., Hong, S.-K., Beppu, T. and Horinouchi, S. (1991) Identification of an A-factor-dependent promoter in the streptomycin biosynthetic gene cluster of Streptomyces griseus. Mol. Gen. Genet. 229, 119-128.
    • (1991) Mol. Gen. Genet , vol.229 , pp. 119-128
    • Vujaklija, D.1    Ueda, K.2    Hong, S.-K.3    Beppu, T.4    Horinouchi, S.5
  • 43
    • 0027251634 scopus 로고
    • Detection of an A-factor-responsive protein that binds to the upstream activation sequence of strR, a regulatory gene for streptomycin biosynthesis in Streptomyces griseus
    • Vujaklija, D., Horinouchi, S. and Beppu, T. (1993) Detection of an A-factor-responsive protein that binds to the upstream activation sequence of strR, a regulatory gene for streptomycin biosynthesis in Streptomyces griseus. J. Bacteriol. 175, 2652-2661.
    • (1993) J. Bacteriol , vol.175 , pp. 2652-2661
    • Vujaklija, D.1    Horinouchi, S.2    Beppu, T.3
  • 44
    • 0028874933 scopus 로고
    • The regulator of streptomycin gene expression, StrR, of Streptomyces griseus is a DNA binding activator protein with multiple recognition sites
    • Retzlaff, L. and Distler, J. (1995) The regulator of streptomycin gene expression, StrR, of Streptomyces griseus is a DNA binding activator protein with multiple recognition sites. Mol. Microbiol. 18, 151-162.
    • (1995) Mol. Microbiol , vol.18 , pp. 151-162
    • Retzlaff, L.1    Distler, J.2
  • 45
    • 0032847109 scopus 로고    scopus 로고
    • The A-factor regulatory cascade leading to streptomycin biosynthesis in Streptomyces griseus: Identification of a target gene of the A-factor receptor
    • Ohnishi, Y., Kameyama, S., Onaka, H. and Horinouchi, S. (1999) The A-factor regulatory cascade leading to streptomycin biosynthesis in Streptomyces griseus: identification of a target gene of the A-factor receptor. Mol. Microbiol. 34, 102-111.
    • (1999) Mol. Microbiol , vol.34 , pp. 102-111
    • Ohnishi, Y.1    Kameyama, S.2    Onaka, H.3    Horinouchi, S.4
  • 46
    • 34247595520 scopus 로고    scopus 로고
    • A-factor and phosphate-depletion signals are transmitted to the grixazone biosynthesis genes via the pathway-specific transcriptional activator GriR
    • Higashi, T., Iwasaki, Y., Ohnishi, Y. and Horinouchi, S. (2007) A-factor and phosphate-depletion signals are transmitted to the grixazone biosynthesis genes via the pathway-specific transcriptional activator GriR. J. Bacteriol. 189, 3515-3524.
    • (2007) J. Bacteriol , vol.189 , pp. 3515-3524
    • Higashi, T.1    Iwasaki, Y.2    Ohnishi, Y.3    Horinouchi, S.4
  • 47
    • 0033877257 scopus 로고    scopus 로고
    • AdsA) that is essential for morphological development in Streptomyces griseus
    • AdsA) that is essential for morphological development in Streptomyces griseus. J. Bacteriol. 182, 4596-4605.
    • (2000) J. Bacteriol , vol.182 , pp. 4596-4605
    • Yamazaki, H.1    Ohnishi, Y.2    Horinouchi, S.3
  • 48
    • 3242891579 scopus 로고    scopus 로고
    • DNA-binding specificity of AdpA, a transcriptional activator in the Afactor regulatory cascade in Streptomyces griseus
    • Yamazaki, H., Tomono, A., Ohnishi, Y. and Horinouchi, S. (2004) DNA-binding specificity of AdpA, a transcriptional activator in the Afactor regulatory cascade in Streptomyces griseus. Mol. Microbiol. 53, 555-572.
    • (2004) Mol. Microbiol , vol.53 , pp. 555-572
    • Yamazaki, H.1    Tomono, A.2    Ohnishi, Y.3    Horinouchi, S.4
  • 49
    • 0031683054 scopus 로고    scopus 로고
    • Characterization of an A-factor-responsive repressor for amfR essential for onset of aerial mycelium formation in Streptomyces griseus
    • Ueda, K., Hsheh, C.-W., Tosaki, T., Shinkawa, H., Beppu, T. and Horinouchi, S. (1998) Characterization of an A-factor-responsive repressor for amfR essential for onset of aerial mycelium formation in Streptomyces griseus. J. Bacteriol. 180, 5085-5093.
    • (1998) J. Bacteriol , vol.180 , pp. 5085-5093
    • Ueda, K.1    Hsheh, C.-W.2    Tosaki, T.3    Shinkawa, H.4    Beppu, T.5    Horinouchi, S.6
  • 50
    • 0344395007 scopus 로고    scopus 로고
    • amfR, an essential gene for aerial mycelium formation, is a member of the AdpA regulon in the A-factor regulatory cascade in Streptomyces griseus
    • Yamazaki, H., Takano, Y., Ohnishi, Y. and Horinouchi, S. (2003) amfR, an essential gene for aerial mycelium formation, is a member of the AdpA regulon in the A-factor regulatory cascade in Streptomyces griseus. Mol. Microbiol. 50, 1173-1187.
    • (2003) Mol. Microbiol , vol.50 , pp. 1173-1187
    • Yamazaki, H.1    Takano, Y.2    Ohnishi, Y.3    Horinouchi, S.4
  • 51
    • 0037317582 scopus 로고    scopus 로고
    • Transcriptional switch on of ssgA by A-factor, which is essential for spore-septum formation in Streptomyces griseus
    • Yamazaki, H., Ohnishi, Y. and Horinouchi, S. (2003) Transcriptional switch on of ssgA by A-factor, which is essential for spore-septum formation in Streptomyces griseus. J. Bacteriol. 185, 1273-1283.
    • (2003) J. Bacteriol , vol.185 , pp. 1273-1283
    • Yamazaki, H.1    Ohnishi, Y.2    Horinouchi, S.3
  • 52
    • 0036837749 scopus 로고    scopus 로고
    • Control by A-factor of a metalloendopeptidase gene involved in aerial mycelium formation in Streptomyces griseus
    • Kato, J., Suzuki, A., Yamazaki, H., Ohnishi, Y. and Horinouchi, S. (2002) Control by A-factor of a metalloendopeptidase gene involved in aerial mycelium formation in Streptomyces griseus. J. Bacteriol. 184, 6016-6025.
    • (2002) J. Bacteriol , vol.184 , pp. 6016-6025
    • Kato, J.1    Suzuki, A.2    Yamazaki, H.3    Ohnishi, Y.4    Horinouchi, S.5
  • 53
    • 11144249979 scopus 로고    scopus 로고
    • Transcriptional control by A-factor of two trypsin genes in Streptomyces griseus
    • Kato, J., Chi, W.-J., Ohnishi, Y., Hong, S.-K. and Horinouchi, S. (2005) Transcriptional control by A-factor of two trypsin genes in Streptomyces griseus. J. Bacteriol. 187, 286-295.
    • (2005) J. Bacteriol , vol.187 , pp. 286-295
    • Kato, J.1    Chi, W.-J.2    Ohnishi, Y.3    Hong, S.-K.4    Horinouchi, S.5
  • 54
    • 24944496815 scopus 로고    scopus 로고
    • Three chymotrypsin genes are members of the AdpA regulon in the A-factor regulatory cascade in Streptomyces griseus
    • Tomono, A., Tsai, Y., Ohnishi, Y. and Horinouchi, S. (2005) Three chymotrypsin genes are members of the AdpA regulon in the A-factor regulatory cascade in Streptomyces griseus. J. Bacteriol. 187, 6341-6353.
    • (2005) J. Bacteriol , vol.187 , pp. 6341-6353
    • Tomono, A.1    Tsai, Y.2    Ohnishi, Y.3    Horinouchi, S.4
  • 55
    • 33749002271 scopus 로고    scopus 로고
    • Control of the Streptomyces subtilisin inhibitor gene by AdpA in the A-factor regulatory cascade in Streptomyces griseus
    • Hirano, S., Kato, J., Ohnishi, Y. and Horinouchi, S. (2006) Control of the Streptomyces subtilisin inhibitor gene by AdpA in the A-factor regulatory cascade in Streptomyces griseus. J. Bacteriol. 188, 6207-6216.
    • (2006) J. Bacteriol , vol.188 , pp. 6207-6216
    • Hirano, S.1    Kato, J.2    Ohnishi, Y.3    Horinouchi, S.4
  • 56
    • 0039820099 scopus 로고    scopus 로고
    • Eubacterial sigmafactors
    • Wösten, M. M. S. M. (1998) Eubacterial sigmafactors. FEMS Microbiol. Rev. 22, 127-150.
    • (1998) FEMS Microbiol. Rev , vol.22 , pp. 127-150
    • Wösten, M.M.S.M.1
  • 57
    • 33645064834 scopus 로고    scopus 로고
    • Morphogenetic surfactants and their role in the formation of aerial hyphae in Streptomyces coelicolor
    • Willey, J. M., Willems, A., Kodani, S. and Nodwell, J. R. (2006) Morphogenetic surfactants and their role in the formation of aerial hyphae in Streptomyces coelicolor. Mol. Microbiol. 59, 731-742.
    • (2006) Mol. Microbiol , vol.59 , pp. 731-742
    • Willey, J.M.1    Willems, A.2    Kodani, S.3    Nodwell, J.R.4
  • 59
    • 0031009509 scopus 로고    scopus 로고
    • Expression analysis of the ssgA gene product, associated with sporulation and cell division in Streptomyces griseus
    • Kawamoto, S., Watanabe, H., Hesketh, A., Ensign, J. C. and Ochi, K. (1997) Expression analysis of the ssgA gene product, associated with sporulation and cell division in Streptomyces griseus. Microbiology 143, 1077-1086.
    • (1997) Microbiology , vol.143 , pp. 1077-1086
    • Kawamoto, S.1    Watanabe, H.2    Hesketh, A.3    Ensign, J.C.4    Ochi, K.5
  • 60
    • 20444379644 scopus 로고    scopus 로고
    • Autorepression of AdpA of the AraC/XylS family, a key transcriptional activator in the A-factor regulatory cascade in Streptomyces griseus
    • Kato, J., Ohnishi, Y. and Horinouchi, S. (2005) Autorepression of AdpA of the AraC/XylS family, a key transcriptional activator in the A-factor regulatory cascade in Streptomyces griseus. J. Mol. Biol. 350, 12-26.
    • (2005) J. Mol. Biol , vol.350 , pp. 12-26
    • Kato, J.1    Ohnishi, Y.2    Horinouchi, S.3
  • 61
    • 0035788803 scopus 로고    scopus 로고
    • A complex role for the γ-butyrolactones SCB1 in regulating antibiotic production in Streptomyces coelicolor A3(2)
    • Takano, E., Chakraburtty, R., Nihira, T., Yamada, Y. and Bibb, M. J. (2001) A complex role for the γ-butyrolactones SCB1 in regulating antibiotic production in Streptomyces coelicolor A3(2). Mol. Microbiol. 41, 1015-1028.
    • (2001) Mol. Microbiol , vol.41 , pp. 1015-1028
    • Takano, E.1    Chakraburtty, R.2    Nihira, T.3    Yamada, Y.4    Bibb, M.J.5
  • 62
    • 0034972542 scopus 로고    scopus 로고
    • Gene replacement analysis of the butyrolactone autoregulator receptor (FarA) reveals that FarA acts as a novel regulator in secondary metabolism of Streptomyces lavendulae FRI-5
    • Kitani, S., Yamada, Y. and Nihira, T. (2001) Gene replacement analysis of the butyrolactone autoregulator receptor (FarA) reveals that FarA acts as a novel regulator in secondary metabolism of Streptomyces lavendulae FRI-5. J. Bacteriol. 183, 4357-4363.
    • (2001) J. Bacteriol , vol.183 , pp. 4357-4363
    • Kitani, S.1    Yamada, Y.2    Nihira, T.3
  • 63
    • 34447328485 scopus 로고    scopus 로고
    • Evolution of γ-butyrolactone synthases and receptors in Streptomyces
    • Nishida, H., Ohnishi, Y., Beppu, T. and Horinouchi, S. (2007) Evolution of γ-butyrolactone synthases and receptors in Streptomyces. Environ. Microbiol. 9, 1986-1994.
    • (2007) Environ. Microbiol , vol.9 , pp. 1986-1994
    • Nishida, H.1    Ohnishi, Y.2    Beppu, T.3    Horinouchi, S.4
  • 64
    • 1942469383 scopus 로고    scopus 로고
    • The evolutionary history of quorum-sensing systems in bacteria
    • Lerat, E. and Moran, N. A. (2004) The evolutionary history of quorum-sensing systems in bacteria. Mol. Biol. Evol. 21, 903-913.
    • (2004) Mol. Biol. Evol , vol.21 , pp. 903-913
    • Lerat, E.1    Moran, N.A.2
  • 65
    • 24944465645 scopus 로고    scopus 로고
    • The A-factor regulatory cascade that leads to morphological development and secondary metabolism in Streptomyces
    • Ohnishi, Y. and Horinouchi, S. (2004) The A-factor regulatory cascade that leads to morphological development and secondary metabolism in Streptomyces. Biofilms 1, 319-328.
    • (2004) Biofilms , vol.1 , pp. 319-328
    • Ohnishi, Y.1    Horinouchi, S.2


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.