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Volumn 13, Issue 36, 2007, Pages 3701-3710

Immune-mediated mechanisms in atherosclerosis: Prevention and treatment of clinical manifestations

Author keywords

Atherosclerosis; Cardiovascular disease; Immune mechanisms; Immunomodulatory therapies; Inflammation; Plaque

Indexed keywords

ACETYLSALICYLIC ACID; ANGIOTENSIN RECEPTOR ANTAGONIST; ANTIBIOTIC AGENT; ANTITHROMBOCYTIC AGENT; ANTIVIRUS AGENT; C REACTIVE PROTEIN; CD3 ANTIBODY; CLOPIDOGREL; CORTICOSTEROID; DIPEPTIDYL CARBOXYPEPTIDASE INHIBITOR; DOXYCYCLINE; GLITAZONE DERIVATIVE; HEAT SHOCK PROTEIN; HYDROXYMETHYLGLUTARYL COENZYME A REDUCTASE INHIBITOR; IMMUNOGLOBULIN M ANTIBODY; IMMUNOMODULATING AGENT; IMMUNOSUPPRESSIVE AGENT; INFLUENZA VACCINE; MACROLIDE; OXIDIZED LOW DENSITY LIPOPROTEIN RECEPTOR; PEXELIZUMAB; PNEUMOCOCCUS VACCINE; PROTEINASE INHIBITOR; PROTON PUMP INHIBITOR; RAPAMYCIN; TUMOR NECROSIS FACTOR ALPHA; TUMOR NECROSIS FACTOR ALPHA ANTIBODY; TUMOR NECROSIS FACTOR ALPHA INHIBITOR; TUMOR NECROSIS FACTOR RELATED APOPTOSIS INDUCING LIGAND; UNINDEXED DRUG;

EID: 37449001497     PISSN: 13816128     EISSN: None     Source Type: Journal    
DOI: 10.2174/138161207783018626     Document Type: Review
Times cited : (15)

References (150)
  • 1
    • 17644412023 scopus 로고    scopus 로고
    • Inflammation, atherosclerosis, and coronary artery disease
    • Hansson GK. Inflammation, atherosclerosis, and coronary artery disease. N Engl J Med 2005; 352: 1685-95.
    • (2005) N Engl J Med , vol.352 , pp. 1685-1695
    • Hansson, G.K.1
  • 2
    • 0037180771 scopus 로고    scopus 로고
    • Inflammation in atherosclerosis
    • Libby P. Inflammation in atherosclerosis. Nature 2002; 420: 868-74.
    • (2002) Nature , vol.420 , pp. 868-874
    • Libby, P.1
  • 3
    • 0028085059 scopus 로고
    • Site of intimal rupture or erosion of thrombosed coronary atherosclerotic plaques is characterized by an inflammatory process irrespective of the dominant plaque morphology
    • van der Wal AC, Becker AE, van der Loos CM, Das PK. Site of intimal rupture or erosion of thrombosed coronary atherosclerotic plaques is characterized by an inflammatory process irrespective of the dominant plaque morphology. Circulation 1994; 89: 36-44.
    • (1994) Circulation , vol.89 , pp. 36-44
    • van der Wal, A.C.1    Becker, A.E.2    van der Loos, C.M.3    Das, P.K.4
  • 4
    • 33845428041 scopus 로고    scopus 로고
    • Pathogen-sensing plasmacytoid dendritic cells stimulate cyto-toxic T-cell function in the atherosclerotic plaque through interferon-alpha
    • Niessner A, Sato K, Chaikof EL, Colmegna I, Goronzy JJ, Weyand CM. Pathogen-sensing plasmacytoid dendritic cells stimulate cyto-toxic T-cell function in the atherosclerotic plaque through interferon-alpha. Circulation 2006; 114: 2482-9.
    • (2006) Circulation , vol.114 , pp. 2482-2489
    • Niessner, A.1    Sato, K.2    Chaikof, E.L.3    Colmegna, I.4    Goronzy, J.J.5    Weyand, C.M.6
  • 5
    • 4043114983 scopus 로고    scopus 로고
    • Emergence of dendritic cells in rupture-prone regions of vulnerable carotid plaques
    • Yilmaz A, Lochno M, Traeg F, Cicha I, Reiss C, Stumpf C, et al. Emergence of dendritic cells in rupture-prone regions of vulnerable carotid plaques. Atherosclerosis 2004; 176: 101-10.
    • (2004) Atherosclerosis , vol.176 , pp. 101-110
    • Yilmaz, A.1    Lochno, M.2    Traeg, F.3    Cicha, I.4    Reiss, C.5    Stumpf, C.6
  • 6
    • 1642459098 scopus 로고    scopus 로고
    • Activation of arterial wall dendritic cells and breakdown of self-tolerance in giant cell arteritis
    • Ma-Krupa W, Jeon MS, Spoerl S, Tedder TF, Goronzy JJ, Weyand CM. Activation of arterial wall dendritic cells and breakdown of self-tolerance in giant cell arteritis. J Exp Med 2004; 199 173-83.
    • (2004) J Exp Med , vol.199 , pp. 173-183
    • Ma-Krupa, W.1    Jeon, M.S.2    Spoerl, S.3    Tedder, T.F.4    Goronzy, J.J.5    Weyand, C.M.6
  • 7
    • 33645064033 scopus 로고    scopus 로고
    • Detection of diverse bacterial signatures in atherosclerotic lesions of patients with coronary heart disease
    • Ott SJ, El Mokhtari NE, Musfeldt M, Hellmig S, Freitag S, Rehman A, et al. Detection of diverse bacterial signatures in atherosclerotic lesions of patients with coronary heart disease: Circulation 2006; 113: 929-37.
    • (2006) Circulation , vol.113 , pp. 929-937
    • Ott, S.J.1    El Mokhtari, N.E.2    Musfeldt, M.3    Hellmig, S.4    Freitag, S.5    Rehman, A.6
  • 8
    • 0035830435 scopus 로고    scopus 로고
    • Link between infection and atherosclerosis: Who are the culprits: viruses, bacteria, both, or neither?
    • Shah PK. Link between infection and atherosclerosis: who are the culprits: viruses, bacteria, both, or neither? Circulation 2001; 103: 5-6.
    • (2001) Circulation , vol.103 , pp. 5-6
    • Shah, P.K.1
  • 9
    • 0033105576 scopus 로고    scopus 로고
    • The atherogenic effects of chlamydia are dependent on serum cholesterol and specific to Chlamydia pneumoniae
    • Hu H, Pierce GN, Zhong G. The atherogenic effects of chlamydia are dependent on serum cholesterol and specific to Chlamydia pneumoniae. J Clin Invest 1999; 103: 747-53.
    • (1999) J Clin Invest , vol.103 , pp. 747-753
    • Hu, H.1    Pierce, G.N.2    Zhong, G.3
  • 10
    • 0026595043 scopus 로고
    • Chronic Chlamydia pneumoniae infection as a risk factor for coronary heart disease in the Helsinki Heart Study
    • Saikku P, Leinonen M, Tenkanen L, Linnanmaki E, Ekman MR, Manninen V, et al. Chronic Chlamydia pneumoniae infection as a risk factor for coronary heart disease in the Helsinki Heart Study. Ann Intern Med 1992; 116:273-8.
    • (1992) Ann Intern Med , vol.116 , pp. 273-278
    • Saikku, P.1    Leinonen, M.2    Tenkanen, L.3    Linnanmaki, E.4    Ekman, M.R.5    Manninen, V.6
  • 11
    • 0037898179 scopus 로고    scopus 로고
    • Polymorphic membrane protein (PNT) 20 and PMP 21 of Chlamydia pneumoniae induce proinflammatory mediators in human endothelial cells in vitro by activation of the nuclear factor-kappaB pathway
    • Niessner A, Kaun C, Zorn G, Speidl W, Turel Z, Christiansen G, et al. Polymorphic membrane protein (PNT) 20 and PMP 21 of Chlamydia pneumoniae induce proinflammatory mediators in human endothelial cells in vitro by activation of the nuclear factor-kappaB pathway. J Infect Dis 2003; 188: 108-13.
    • (2003) J Infect Dis , vol.188 , pp. 108-113
    • Niessner, A.1    Kaun, C.2    Zorn, G.3    Speidl, W.4    Turel, Z.5    Christiansen, G.6
  • 12
    • 0032575305 scopus 로고    scopus 로고
    • Chlamydial heat shock protein 60 localizes in human atheroma and regulates macrophage tumor necrosis factor-alpha and matrix metalloproteinase expression
    • Kol A, Sukhova GK, Lichtman AH, Libby P. Chlamydial heat shock protein 60 localizes in human atheroma and regulates macrophage tumor necrosis factor-alpha and matrix metalloproteinase expression. Circulation 1998; 98: 300-7.
    • (1998) Circulation , vol.98 , pp. 300-307
    • Kol, A.1    Sukhova, G.K.2    Lichtman, A.H.3    Libby, P.4
  • 13
    • 0020538854 scopus 로고
    • The genus-specific antigen of Chlamydia: Resemblance to the lipopolysaccharide of enteric bacteria
    • Nurminen M, Leinonen M, Saikku P, Makela PH. The genus-specific antigen of Chlamydia: resemblance to the lipopolysaccharide of enteric bacteria. Science 1983; 220: 1279-81.
    • (1983) Science , vol.220 , pp. 1279-1281
    • Nurminen, M.1    Leinonen, M.2    Saikku, P.3    Makela, P.H.4
  • 14
    • 0242432600 scopus 로고    scopus 로고
    • Detection of Chlamydiae pneumoniae but not Helicobacter pylori DNA in atherosclerosis plaques
    • Dore MP, Sepulveda AR, Bacciu PP, Blasi F, Simula L, Marras L, et al. Detection of Chlamydiae pneumoniae but not Helicobacter pylori DNA in atherosclerosis plaques. Dig Dis Sci 2003; 48: 945-51.
    • (2003) Dig Dis Sci , vol.48 , pp. 945-951
    • Dore, M.P.1    Sepulveda, A.R.2    Bacciu, P.P.3    Blasi, F.4    Simula, L.5    Marras, L.6
  • 15
    • 0034460491 scopus 로고    scopus 로고
    • Detection of Chlamydia pneumoniae and Helicobacter pylori DNA in human atherosclerotic plaques by PCR
    • Farsak B, Yildirir A, Akyon Y, Pinar A, Oc M, Boke E, et al. Detection of Chlamydia pneumoniae and Helicobacter pylori DNA in human atherosclerotic plaques by PCR. J Clin Microbiol 2000; 38: 4408-11.
    • (2000) J Clin Microbiol , vol.38 , pp. 4408-4411
    • Farsak, B.1    Yildirir, A.2    Akyon, Y.3    Pinar, A.4    Oc, M.5    Boke, E.6
  • 16
    • 32844454831 scopus 로고    scopus 로고
    • Detection of Chlamydia pneumoniae and Helicobacter pylori in atherosclerotic plaques of carotid artery by polymerase chain reaction
    • Kaplan M, Yavuz SS, Cinar B, Koksal V, Kut MS, Yapici F, et al. Detection of Chlamydia pneumoniae and Helicobacter pylori in atherosclerotic plaques of carotid artery by polymerase chain reaction. Int J Infect Dis 2006; 10: 116-23.
    • (2006) Int J Infect Dis , vol.10 , pp. 116-123
    • Kaplan, M.1    Yavuz, S.S.2    Cinar, B.3    Koksal, V.4    Kut, M.S.5    Yapici, F.6
  • 17
    • 33751248744 scopus 로고    scopus 로고
    • No evidence for a direct role of Helicobacter pylori and Mycoplasma pneumoniae in carotid artery atherosclerosis
    • Weiss TW, Kvakan H, Kaun C, Prager M, Speidl WS, Zorn G, et al. No evidence for a direct role of Helicobacter pylori and Mycoplasma pneumoniae in carotid artery atherosclerosis. J Clin Pathol 2006; 59: 1186-90.
    • (2006) J Clin Pathol , vol.59 , pp. 1186-1190
    • Weiss, T.W.1    Kvakan, H.2    Kaun, C.3    Prager, M.4    Speidl, W.S.5    Zorn, G.6
  • 18
    • 0037059862 scopus 로고    scopus 로고
    • Influence of Helicobacter pylori infection during atherogenesis in vivo in mice
    • Mach F, Sukhova GK, Michetti M, Libby P, Michetti P. Influence of Helicobacter pylori infection during atherogenesis in vivo in mice. Circ Res 2002; 90: E1-4.
    • (2002) Circ Res , vol.90
    • Mach, F.1    Sukhova, G.K.2    Michetti, M.3    Libby, P.4    Michetti, P.5
  • 19
    • 0344269334 scopus 로고    scopus 로고
    • Helicobacter pylori seropositivity and coronary heart disease incidence. Atherosclerosis Risk In Communities (ARIC) Study Investigators
    • Folsom AR, Nieto FJ, Sorlie P, Chambless LE, Graham DY. Helicobacter pylori seropositivity and coronary heart disease incidence. Atherosclerosis Risk In Communities (ARIC) Study Investigators. Circulation 1998; 98: 845-50.
    • (1998) Circulation , vol.98 , pp. 845-850
    • Folsom, A.R.1    Nieto, F.J.2    Sorlie, P.3    Chambless, L.E.4    Graham, D.Y.5
  • 21
    • 0032578575 scopus 로고    scopus 로고
    • Relation of Helicobacter pylori infection to 13-year mortality and incident ischemic heart disease in the caerphilly prospective heart disease study
    • Strachan DP, Mendall MA, Carrington D, Butland BK, Yarnell JW, Sweetnam PM, et al. Relation of Helicobacter pylori infection to 13-year mortality and incident ischemic heart disease in the caerphilly prospective heart disease study. Circulation 1998; 98: 1286-90.
    • (1998) Circulation , vol.98 , pp. 1286-1290
    • Strachan, D.P.1    Mendall, M.A.2    Carrington, D.3    Butland, B.K.4    Yarnell, J.W.5    Sweetnam, P.M.6
  • 22
    • 0030724083 scopus 로고    scopus 로고
    • Helicobacter pylori infection and mortality from ischaemic heart disease: Negative result from a large, prospective study
    • Wald NJ, Law MR, Morris JK, Bagnall AM. Helicobacter pylori infection and mortality from ischaemic heart disease: negative result from a large, prospective study. BMJ 1997; 315: 1199-201.
    • (1997) BMJ , vol.315 , pp. 1199-1201
    • Wald, N.J.1    Law, M.R.2    Morris, J.K.3    Bagnall, A.M.4
  • 23
  • 25
    • 33644977990 scopus 로고    scopus 로고
    • Periodontal infections and coronary heart disease: Role of periodontal bacteria and importance of total pathogen burden in the Coronary Event and Periodontal Disease (CORODONT) study
    • Spahr A, Klein E, Khuseyinova N, Boeckh C, Muche R, Kunzec M, et al. Periodontal infections and coronary heart disease: role of periodontal bacteria and importance of total pathogen burden in the Coronary Event and Periodontal Disease (CORODONT) study. Arch Intern Med 2006; 166: 554-9.
    • (2006) Arch Intern Med , vol.166 , pp. 554-559
    • Spahr, A.1    Klein, E.2    Khuseyinova, N.3    Boeckh, C.4    Muche, R.5    Kunzec, M.6
  • 26
    • 21544471522 scopus 로고    scopus 로고
    • Porphyromonas gingivalis bacteremia induces coronary and aortic atherosclerosis in normocholesterolemic and hypercholesterolemic pigs
    • Brodala N, Merricks EP, Bellinger DA, Damrongsri D, Offenbacher S, Beck J, et al. Porphyromonas gingivalis bacteremia induces coronary and aortic atherosclerosis in normocholesterolemic and hypercholesterolemic pigs. Arterioscler Thromb Vasc Biol 2005; 25: 1446-51.
    • (2005) Arterioscler Thromb Vasc Biol , vol.25 , pp. 1446-1451
    • Brodala, N.1    Merricks, E.P.2    Bellinger, D.A.3    Damrongsri, D.4    Offenbacher, S.5    Beck, J.6
  • 27
    • 2942544238 scopus 로고    scopus 로고
    • Innate immune recognition of invasive bacteria accelerates atherosclerosis in apolipoprotein E-deficient mice
    • Gibson FC, 3rd, Hong C, Chou HH, Yumoto H, Chen J, Lien E, et al. Innate immune recognition of invasive bacteria accelerates atherosclerosis in apolipoprotein E-deficient mice. Circulation 2004; 109: 2801-6.
    • (2004) Circulation , vol.109 , pp. 2801-2806
    • Gibson 3rd, F.C.1    Hong, C.2    Chou, H.H.3    Yumoto, H.4    Chen, J.5    Lien, E.6
  • 29
    • 0037133346 scopus 로고    scopus 로고
    • Porphyromonas gingivalis infection accelerates the progression of atherosclerosis in a heterozygous apolipoprotein E-deficient murine model
    • Li L, Messas E, Batista EL Jr, Levine RA, Amar S. Porphyromonas gingivalis infection accelerates the progression of atherosclerosis in a heterozygous apolipoprotein E-deficient murine model. Circulation 2002; 105: 861-7.
    • (2002) Circulation , vol.105 , pp. 861-867
    • Li, L.1    Messas, E.2    Batista Jr, E.L.3    Levine, R.A.4    Amar, S.5
  • 31
  • 32
    • 0035012440 scopus 로고    scopus 로고
    • Cytomegalovirus infection increases development of atherosclerosis in Apolipoprotein-E knockout mice
    • Hsich E, Zhou YF, Paigen B, Johnson TM, Burnett MS, Epstein SE. Cytomegalovirus infection increases development of atherosclerosis in Apolipoprotein-E knockout mice. Atherosclerosis 2001; 156: 23-8.
    • (2001) Atherosclerosis , vol.156 , pp. 23-28
    • Hsich, E.1    Zhou, Y.F.2    Paigen, B.3    Johnson, T.M.4    Burnett, M.S.5    Epstein, S.E.6
  • 33
    • 0034094273 scopus 로고    scopus 로고
    • Accelerated coronary atherosclerosis and arteriosclerosis in young human-immuno-deficiency-virus-positive patients
    • Tabib A, Leroux C, Mornex JF, Loire R. Accelerated coronary atherosclerosis and arteriosclerosis in young human-immuno-deficiency-virus-positive patients. Coron Artery Dis 2000; 11: 41-6.
    • (2000) Coron Artery Dis , vol.11 , pp. 41-46
    • Tabib, A.1    Leroux, C.2    Mornex, J.F.3    Loire, R.4
  • 35
    • 0037463620 scopus 로고    scopus 로고
    • Acute myocardial infarction in human immunodeficiency virus-infected patients
    • Matetzky S, Domingo M, Kar S, Noc M, Shah PK, Kaul S, et al. Acute myocardial infarction in human immunodeficiency virus-infected patients. Arch Intern Med 2003; 163: 457-60.
    • (2003) Arch Intern Med , vol.163 , pp. 457-460
    • Matetzky, S.1    Domingo, M.2    Kar, S.3    Noc, M.4    Shah, P.K.5    Kaul, S.6
  • 36
    • 0033984188 scopus 로고    scopus 로고
    • Effects of total pathogen burden on coronary artery disease risk and C-reactive protein levels
    • Zhu J, Quyyumi AA, Norman JE, Csako G, Waclawiw MA, Shearer GM, et al. Effects of total pathogen burden on coronary artery disease risk and C-reactive protein levels. Am J Cardiol 2000; 85: 140-6.
    • (2000) Am J Cardiol , vol.85 , pp. 140-146
    • Zhu, J.1    Quyyumi, A.A.2    Norman, J.E.3    Csako, G.4    Waclawiw, M.A.5    Shearer, G.M.6
  • 38
    • 0038375997 scopus 로고    scopus 로고
    • Pneumococcal vaccination decreases atherosclerotic lesion formation: Molecular mimicry between Streptococcus pneumoniae and oxidized LDL
    • Binder CJ, Horkko S, Dewan A, Chang MY, Men EP, Goodyear CS, et al. Pneumococcal vaccination decreases atherosclerotic lesion formation: molecular mimicry between Streptococcus pneumoniae and oxidized LDL. Nat Med 2003; 9: 736-43.
    • (2003) Nat Med , vol.9 , pp. 736-743
    • Binder, C.J.1    Horkko, S.2    Dewan, A.3    Chang, M.Y.4    Men, E.P.5    Goodyear, C.S.6
  • 40
    • 0033557202 scopus 로고    scopus 로고
    • Chlamydial and human heat shock protein 60s activate human vascular endothelium, smooth muscle cells, and macrophages
    • Kol A, Bourcier T, Lichtman AH, Libby P. Chlamydial and human heat shock protein 60s activate human vascular endothelium, smooth muscle cells, and macrophages. J Clin Invest 1999; 103: 571-7.
    • (1999) J Clin Invest , vol.103 , pp. 571-577
    • Kol, A.1    Bourcier, T.2    Lichtman, A.H.3    Libby, P.4
  • 41
    • 0037066041 scopus 로고    scopus 로고
    • Expression of toll-like receptors in human atherosclerotic lesions: A possible pathway for plaque activation
    • Edfeldt K, Swedenborg J, Hansson GK, Yan ZQ. Expression of toll-like receptors in human atherosclerotic lesions: a possible pathway for plaque activation. Circulation 2002; 105: 1158-61.
    • (2002) Circulation , vol.105 , pp. 1158-1161
    • Edfeldt, K.1    Swedenborg, J.2    Hansson, G.K.3    Yan, Z.Q.4
  • 42
    • 0035910010 scopus 로고    scopus 로고
    • Toll-like receptor-4 is expressed by macrophages in murine and human lipid-rich atherosclerotic plaques and upregulated by oxidized LDL
    • Xu XH, Shah PK, Faure E, Equils O, Thomas L, Fishbein MC, et al. Toll-like receptor-4 is expressed by macrophages in murine and human lipid-rich atherosclerotic plaques and upregulated by oxidized LDL. Circulation 2001; 104: 3103-8.
    • (2001) Circulation , vol.104 , pp. 3103-3108
    • Xu, X.H.1    Shah, P.K.2    Faure, E.3    Equils, O.4    Thomas, L.5    Fishbein, M.C.6
  • 43
    • 0035253370 scopus 로고    scopus 로고
    • Bacterial lipopolysaccharide and IFN-gamma induce Toll-like receptor 2 and Toll-like receptor 4 expression in human endothelial cells: Role of NF-kappa B activation
    • Faure E, Thomas L, Xu H, Medvedey A, Equils O, Arditi M. Bacterial lipopolysaccharide and IFN-gamma induce Toll-like receptor 2 and Toll-like receptor 4 expression in human endothelial cells: role of NF-kappa B activation. J Immunol 2001; 166: 2018-24.
    • (2001) J Immunol , vol.166 , pp. 2018-2024
    • Faure, E.1    Thomas, L.2    Xu, H.3    Medvedey, A.4    Equils, O.5    Arditi, M.6
  • 44
    • 0036775020 scopus 로고    scopus 로고
    • TLR4-mediated inflammatory activation of human coronary artery endothelial cells by LPS
    • Zeuke S, Ulmer AJ, Kusumoto S, Katus HA, Heine H. TLR4-mediated inflammatory activation of human coronary artery endothelial cells by LPS. Cardiovasc Res 2002; 56: 126-34.
    • (2002) Cardiovasc Res , vol.56 , pp. 126-134
    • Zeuke, S.1    Ulmer, A.J.2    Kusumoto, S.3    Katus, H.A.4    Heine, H.5
  • 45
    • 0033405387 scopus 로고    scopus 로고
    • Association of endotoxemia with carotid atherosclerosis and cardiovascular disease: Prospective results from the Bruneck Study
    • Wiedermann CJ, Kiechl S, Dunzendorfer S, Schratzberger P, Egger G, Oberhollenzer F, et al. Association of endotoxemia with carotid atherosclerosis and cardiovascular disease: prospective results from the Bruneck Study. J Am Coll Cardiol 1999; 34: 1975-81.
    • (1999) J Am Coll Cardiol , vol.34 , pp. 1975-1981
    • Wiedermann, C.J.1    Kiechl, S.2    Dunzendorfer, S.3    Schratzberger, P.4    Egger, G.5    Oberhollenzer, F.6
  • 46
    • 27644568878 scopus 로고    scopus 로고
    • Modulation of atherosclerosis in mice by Toll-like receptor 2
    • Mullick AE, Tobias PS, Curtiss LK. Modulation of atherosclerosis in mice by Toll-like receptor 2. J Clin Invest 2005; 115: 3149-56.
    • (2005) J Clin Invest , vol.115 , pp. 3149-3156
    • Mullick, A.E.1    Tobias, P.S.2    Curtiss, L.K.3
  • 47
    • 3242710174 scopus 로고    scopus 로고
    • Lack of Toll-like receptor 4 or myeloid differentiation factor 88 reduces atherosclerosis and alters plaque phenotype in mice deficient in apolipoprotein E
    • Michelsen KS, Wong MH, Shah PK, Zhang W, Yano J, Doherty TM, et al. Lack of Toll-like receptor 4 or myeloid differentiation factor 88 reduces atherosclerosis and alters plaque phenotype in mice deficient in apolipoprotein E. Proc Natl Acad Sci USA 2004; 101: 10679-84.
    • (2004) Proc Natl Acad Sci USA , vol.101 , pp. 10679-10684
    • Michelsen, K.S.1    Wong, M.H.2    Shah, P.K.3    Zhang, W.4    Yano, J.5    Doherty, T.M.6
  • 48
    • 31344460566 scopus 로고    scopus 로고
    • TRAIL-expressing T cells induce apoptosis of vascular smooth muscle cells in the atherosclerotic plaque
    • Sato K, Niessner A, Kopecky SL, Frye RL, Goronzy JJ, Weyand CM. TRAIL-expressing T cells induce apoptosis of vascular smooth muscle cells in the atherosclerotic plaque. J Exp Med 2006; 203: 239-50.
    • (2006) J Exp Med , vol.203 , pp. 239-250
    • Sato, K.1    Niessner, A.2    Kopecky, S.L.3    Frye, R.L.4    Goronzy, J.J.5    Weyand, C.M.6
  • 49
    • 3242888948 scopus 로고    scopus 로고
    • The role of complement activation in atherosclerosis
    • Niculescu F, Rus H. The role of complement activation in atherosclerosis. Immunol Res 2004; 30: 73-80.
    • (2004) Immunol Res , vol.30 , pp. 73-80
    • Niculescu, F.1    Rus, H.2
  • 50
    • 0033393530 scopus 로고    scopus 로고
    • Complement activation and atherosclerosis
    • Niculescu F, Rus H. Complement activation and atherosclerosis. Mol Immunol 1999; 36: 949-55.
    • (1999) Mol Immunol , vol.36 , pp. 949-955
    • Niculescu, F.1    Rus, H.2
  • 51
    • 27544498810 scopus 로고    scopus 로고
    • Complement component C5a predicts future cardiovascular events in patients with advanced atherosclerosis
    • Speidl WS, Exner M, Amighi J, Kasd SP, Zorn G, Maurer G, et al. Complement component C5a predicts future cardiovascular events in patients with advanced atherosclerosis. Eur Heart J 2005; 26: 2294-9.
    • (2005) Eur Heart J , vol.26 , pp. 2294-2299
    • Speidl, W.S.1    Exner, M.2    Amighi, J.3    Kasd, S.P.4    Zorn, G.5    Maurer, G.6
  • 53
    • 0033958328 scopus 로고    scopus 로고
    • Oligoclonal T cell expansions in atherosclerotic lesions of apolipoprotein E-deficient mice
    • Paulsson G, Zhou X, Tornquist E, Hansson GK. Oligoclonal T cell expansions in atherosclerotic lesions of apolipoprotein E-deficient mice. Arterioscler Thromb Vasc Biol 2000; 20: 10-7.
    • (2000) Arterioscler Thromb Vasc Biol , vol.20 , pp. 10-17
    • Paulsson, G.1    Zhou, X.2    Tornquist, E.3    Hansson, G.K.4
  • 54
    • 0034720851 scopus 로고    scopus 로고
    • Monoclonal T-cell proliferation and plaque instability in acute coronary syndromes
    • Liuzzo G, Goronzy JJ, Yang H, Kopecky SL, Hohnes DR, Frye RL, et al. Monoclonal T-cell proliferation and plaque instability in acute coronary syndromes. Circulation 2000; 101: 2883-8.
    • (2000) Circulation , vol.101 , pp. 2883-2888
    • Liuzzo, G.1    Goronzy, J.J.2    Yang, H.3    Kopecky, S.L.4    Hohnes, D.R.5    Frye, R.L.6
  • 55
    • 33646700957 scopus 로고    scopus 로고
    • Adoptive transfer of CD4+ T cells reactive to modified low-density lipoprotein aggravates atherosclerosis
    • Zhou X, Robertson AK, Hjerpe C, Hansson GK. Adoptive transfer of CD4+ T cells reactive to modified low-density lipoprotein aggravates atherosclerosis. Arterioscler Thromb Vasc Biol 2006; 26 864-70.
    • (2006) Arterioscler Thromb Vasc Biol , vol.26 , pp. 864-870
    • Zhou, X.1    Robertson, A.K.2    Hjerpe, C.3    Hansson, G.K.4
  • 58
    • 0043269270 scopus 로고    scopus 로고
    • De novo expression of killer immunoglobulin-like receptors and signaling proteins regulates the cytotoxic function of CD4 T cells in acute coronary syndromes
    • Nakajima T, Goek O, Zhang X, Kopecky SL, Frye RL, Goronzy JJ, et al. De novo expression of killer immunoglobulin-like receptors and signaling proteins regulates the cytotoxic function of CD4 T cells in acute coronary syndromes. Circ Res 2003; 93: 106-13.
    • (2003) Circ Res , vol.93 , pp. 106-113
    • Nakajima, T.1    Goek, O.2    Zhang, X.3    Kopecky, S.L.4    Frye, R.L.5    Goronzy, J.J.6
  • 59
    • 33745014193 scopus 로고    scopus 로고
    • T cell recognition and killing of vascular smooth muscle cells in acute coronary syndrome
    • Pryshchep S, Sato K, Goronzy JJ, Weyand CM. T cell recognition and killing of vascular smooth muscle cells in acute coronary syndrome. Circ Res 2006; 98: 1168-76.
    • (2006) Circ Res , vol.98 , pp. 1168-1176
    • Pryshchep, S.1    Sato, K.2    Goronzy, J.J.3    Weyand, C.M.4
  • 60
    • 33750501790 scopus 로고    scopus 로고
    • Immunosuppression in atherosclerosis: Mobilizing the opposition within
    • Goronzy JJ, Weyand CM. Immunosuppression in atherosclerosis: mobilizing the opposition within. Circulation 2006; 114: 1901-4.
    • (2006) Circulation , vol.114 , pp. 1901-1904
    • Goronzy, J.J.1    Weyand, C.M.2
  • 62
    • 34247553751 scopus 로고    scopus 로고
    • Association between IgM against an aldehyde-modified peptide in apolipoprotein B-100 and progression of carotid disease
    • Fredrikson GN, Hedblad B, Berglund G, Alm R, Nilsson JA, Schiopu A, et al. Association between IgM against an aldehyde-modified peptide in apolipoprotein B-100 and progression of carotid disease. Stroke 2007; 38: 1495-500.
    • (2007) Stroke , vol.38 , pp. 1495-1500
    • Fredrikson, G.N.1    Hedblad, B.2    Berglund, G.3    Alm, R.4    Nilsson, J.A.5    Schiopu, A.6
  • 63
    • 0035151814 scopus 로고    scopus 로고
    • Antibodies to oxidized LDL in relation to intima-media thickness in carotid and femoral arteries in 58-year-old subjectively clinically healthy men
    • Hulthe J, Bokemark L, Fagerberg B. Antibodies to oxidized LDL in relation to intima-media thickness in carotid and femoral arteries in 58-year-old subjectively clinically healthy men. Arterioscler Thromb Vasc Biol 2001; 21: 101-7.
    • (2001) Arterioscler Thromb Vasc Biol , vol.21 , pp. 101-107
    • Hulthe, J.1    Bokemark, L.2    Fagerberg, B.3
  • 64
    • 33750515883 scopus 로고    scopus 로고
    • Short-term treatment with anti-CD3 antibody reduces the development and progression of atherosclerosis in mice
    • Steffens S, Burger F, Pelli G, Dean Y, Elson G, Kosco-Vilbois M, et al. Short-term treatment with anti-CD3 antibody reduces the development and progression of atherosclerosis in mice. Circulation 2006; 114: 1977-84.
    • (2006) Circulation , vol.114 , pp. 1977-1984
    • Steffens, S.1    Burger, F.2    Pelli, G.3    Dean, Y.4    Elson, G.5    Kosco-Vilbois, M.6
  • 65
    • 0042691806 scopus 로고    scopus 로고
    • Tumor necrosis factor-alpha promotes macrophage-induced vascular smooth muscle cell apoptosis by direct and autocrine mechanisms
    • Boyle JJ, Weissberg PL, Bennett MR. Tumor necrosis factor-alpha promotes macrophage-induced vascular smooth muscle cell apoptosis by direct and autocrine mechanisms. Arterioscler Thromb Vasc Biol 2003; 23: 1553-8.
    • (2003) Arterioscler Thromb Vasc Biol , vol.23 , pp. 1553-1558
    • Boyle, J.J.1    Weissberg, P.L.2    Bennett, M.R.3
  • 67
    • 0028063408 scopus 로고
    • Increased expression of matrix metalloproteinases and matrix degrading activity in vulnerable regions of human atherosclerotic plaques
    • Galis ZS, Sukhova GK, Lark MW, Libby P. Increased expression of matrix metalloproteinases and matrix degrading activity in vulnerable regions of human atherosclerotic plaques. J Clin Invest 1994; 94: 2493-503.
    • (1994) J Clin Invest , vol.94 , pp. 2493-2503
    • Galis, Z.S.1    Sukhova, G.K.2    Lark, M.W.3    Libby, P.4
  • 68
    • 0037381597 scopus 로고    scopus 로고
    • Plasma concentrations and genetic variation of matrix metalloproteinase 9 and prognosis of patients with cardiovascular disease
    • Blankenberg S, Rupprecht HJ, Poirier O, Bickel C, Smieja M, Hafner G, et al. Plasma concentrations and genetic variation of matrix metalloproteinase 9 and prognosis of patients with cardiovascular disease. Circulation 2003; 107: 1579-85.
    • (2003) Circulation , vol.107 , pp. 1579-1585
    • Blankenberg, S.1    Rupprecht, H.J.2    Poirier, O.3    Bickel, C.4    Smieja, M.5    Hafner, G.6
  • 69
    • 18544394788 scopus 로고    scopus 로고
    • Attenuated progression of coronary artery disease after 6 years of multifactorial risk intervention: Role of physical exercise
    • Niebauer J, Hambrecht R, Velich T, Hauer K, Marburger C, Kalberer B, et al. Attenuated progression of coronary artery disease after 6 years of multifactorial risk intervention: role of physical exercise. Circulation 1997; 96: 2534-41.
    • (1997) Circulation , vol.96 , pp. 2534-2541
    • Niebauer, J.1    Hambrecht, R.2    Velich, T.3    Hauer, K.4    Marburger, C.5    Kalberer, B.6
  • 70
    • 18144408371 scopus 로고    scopus 로고
    • Adipose tissue, adipokines, and inflammation
    • quiz 920
    • Fantuzzi G. Adipose tissue, adipokines, and inflammation. J Allergy Clin Immunol 2005; 115: 911-19; quiz 920.
    • (2005) J Allergy Clin Immunol , vol.115 , pp. 911-919
    • Fantuzzi, G.1
  • 71
    • 0027475199 scopus 로고
    • The association of changes in physical-activity level and other lifestyle characteristics with mortality among men
    • Paffenbarger RS Jr, Hyde RT, Wing AL, Lee IM, Jung DL, Kampert JB. The association of changes in physical-activity level and other lifestyle characteristics with mortality among men. N Engl J Med 1993; 328: 538-45.
    • (1993) N Engl J Med , vol.328 , pp. 538-545
    • Paffenbarger Jr, R.S.1    Hyde, R.T.2    Wing, A.L.3    Lee, I.M.4    Jung, D.L.5    Kampert, J.B.6
  • 72
    • 33646968283 scopus 로고    scopus 로고
    • Anti-inflammatory effects of physical exercise. A new mechanism to explain the benefits of cardiac rehabilitation?
    • Gielen S, Walther C, Schuler G, Hambrecht R. Anti-inflammatory effects of physical exercise. A new mechanism to explain the benefits of cardiac rehabilitation? J Cardiopulm Rehabil 2005; 25: 339-42.
    • (2005) J Cardiopulm Rehabil , vol.25 , pp. 339-342
    • Gielen, S.1    Walther, C.2    Schuler, G.3    Hambrecht, R.4
  • 73
    • 0033549059 scopus 로고    scopus 로고
    • Longterm exercise and atherogenic activity of blood mononuclear cells in persons at risk of developing ischemic heart disease
    • Smith JK, Dykes R, Douglas JE, Krishnaswamy G, Berk S. Longterm exercise and atherogenic activity of blood mononuclear cells in persons at risk of developing ischemic heart disease. JAMA 1999; 281: 1722-7.
    • (1999) JAMA , vol.281 , pp. 1722-1727
    • Smith, J.K.1    Dykes, R.2    Douglas, J.E.3    Krishnaswamy, G.4    Berk, S.5
  • 74
    • 33645841638 scopus 로고    scopus 로고
    • Endurance training reduces circulating inflammatory markers in persons at risk of coronary events: Impact on plaque stabilization?
    • Niessner A, Richter B, Penka M, Steiner S, Strasser B, Ziegler S, et al. Endurance training reduces circulating inflammatory markers in persons at risk of coronary events: impact on plaque stabilization? Atherosclerosis 2006; 186: 160-5.
    • (2006) Atherosclerosis , vol.186 , pp. 160-165
    • Niessner, A.1    Richter, B.2    Penka, M.3    Steiner, S.4    Strasser, B.5    Ziegler, S.6
  • 75
    • 1542603465 scopus 로고    scopus 로고
    • Reduction in C-reactive protein through cardiac rehabilitation and exercise training
    • Milani RV, Lavie CJ, Mehra MR. Reduction in C-reactive protein through cardiac rehabilitation and exercise training. J Am Coll Cardiol 2004; 43: 1056-61.
    • (2004) J Am Coll Cardiol , vol.43 , pp. 1056-1061
    • Milani, R.V.1    Lavie, C.J.2    Mehra, M.R.3
  • 76
    • 21544452747 scopus 로고    scopus 로고
    • Statins decrease Toll-like receptor 4 expression and downstream signaling in human CD14+ monocytcs
    • Methe H, Kim JO, Kofler S, Nabauer M, Weis M. Statins decrease Toll-like receptor 4 expression and downstream signaling in human CD14+ monocytcs. Arterioscler Thromb Vase Biol 2005; 25: 1439-45.
    • (2005) Arterioscler Thromb Vase Biol , vol.25 , pp. 1439-1445
    • Methe, H.1    Kim, J.O.2    Kofler, S.3    Nabauer, M.4    Weis, M.5
  • 77
    • 33750360916 scopus 로고    scopus 로고
    • Simvastatin suppresses endotoxin-induced upregulation of toll-like receptors 4 and 2 in vivo
    • Niessner A, Steiner S, Speidl WS, Pleiner J, Seidinger D, Maurer G, et al. Simvastatin suppresses endotoxin-induced upregulation of toll-like receptors 4 and 2 in vivo. Atherosclerosis 2006; 189: 408-13.
    • (2006) Atherosclerosis , vol.189 , pp. 408-413
    • Niessner, A.1    Steiner, S.2    Speidl, W.S.3    Pleiner, J.4    Seidinger, D.5    Maurer, G.6
  • 78
    • 0029858008 scopus 로고    scopus 로고
    • Lovastatin inhibits T-cell antigen receptor signaling independent of its effects on ras
    • Goldman F, Hohl RJ, Crabtree J, Lewis-Tibesar K, Koretzky G. Lovastatin inhibits T-cell antigen receptor signaling independent of its effects on ras. Blood 1996; 88: 4611-9.
    • (1996) Blood , vol.88 , pp. 4611-4619
    • Goldman, F.1    Hohl, R.J.2    Crabtree, J.3    Lewis-Tibesar, K.4    Koretzky, G.5
  • 79
    • 0034533147 scopus 로고    scopus 로고
    • Statins as a newly recögnized type of immunomodulator
    • Kwak B, Mulhaupt F, Myit S, Mach F. Statins as a newly recögnized type of immunomodulator. Nat Med 2000; 6: 1399-402.
    • (2000) Nat Med , vol.6 , pp. 1399-1402
    • Kwak, B.1    Mulhaupt, F.2    Myit, S.3    Mach, F.4
  • 80
    • 15944410609 scopus 로고    scopus 로고
    • Intensive lipid lowering with atorvastatin in patients with stable coronary disease
    • LaRosa JC, Grundy SM, Waters DD, Shear C, Barter P, Fruchart JC, et al. Intensive lipid lowering with atorvastatin in patients with stable coronary disease. N Engl J Med 2005; 352: 1425-35.
    • (2005) N Engl J Med , vol.352 , pp. 1425-1435
    • LaRosa, J.C.1    Grundy, S.M.2    Waters, D.D.3    Shear, C.4    Barter, P.5    Fruchart, J.C.6
  • 81
    • 2642533516 scopus 로고    scopus 로고
    • Effects of HMG-CoA reductase inhibitors on endothelial function: Role of microdomains and oxidative stress
    • Mason RP, Walter MF, Jacob RF. Effects of HMG-CoA reductase inhibitors on endothelial function: role of microdomains and oxidative stress. Circulation 2004; 109(21 Suppl 1): 1134-41.
    • (2004) Circulation , vol.109 , Issue.21 SUPPL. 1 , pp. 1134-1141
    • Mason, R.P.1    Walter, M.F.2    Jacob, R.F.3
  • 82
  • 83
    • 31344443020 scopus 로고    scopus 로고
    • Mora S, Ridker PM. Justification for the Use of Statins in Primary Prevention: an Intervention Trial Evaluating Rosuvastatin (JUPITER) - can C-reactive protein be used to target statin therapy in primary prevention? Am J Cardiol 2006; 97(2A): 33A-41A.
    • Mora S, Ridker PM. Justification for the Use of Statins in Primary Prevention: an Intervention Trial Evaluating Rosuvastatin (JUPITER) - can C-reactive protein be used to target statin therapy in primary prevention? Am J Cardiol 2006; 97(2A): 33A-41A.
  • 84
    • 0029823037 scopus 로고    scopus 로고
    • Increased accumulation of tissue ACE in human atherosclerotic coronary artery disease
    • Diet F, Pratt RE, Berry GJ, Momose N, Gibbons GH, Dzau VJ. Increased accumulation of tissue ACE in human atherosclerotic coronary artery disease. Circulation 1996; 94: 2756-67.
    • (1996) Circulation , vol.94 , pp. 2756-2767
    • Diet, F.1    Pratt, R.E.2    Berry, G.J.3    Momose, N.4    Gibbons, G.H.5    Dzau, V.J.6
  • 85
    • 0034724305 scopus 로고    scopus 로고
    • Expression of angiotensin II and interleukin 6 in human coronary atherosclerotic plaques: Potential implications for inflammation and plaque instability
    • Schieffer B, Schieffer E, Hilfiker-Kleiner D, Hilfiker A, Kovanen PT, Kaartinen M, et al. Expression of angiotensin II and interleukin 6 in human coronary atherosclerotic plaques: potential implications for inflammation and plaque instability. Circulation 2000; 101: 1372-8.
    • (2000) Circulation , vol.101 , pp. 1372-1378
    • Schieffer, B.1    Schieffer, E.2    Hilfiker-Kleiner, D.3    Hilfiker, A.4    Kovanen, P.T.5    Kaartinen, M.6
  • 86
    • 0031823651 scopus 로고    scopus 로고
    • The effect of renin-angiotensin system inhibitors on pro- and anti-inflammatory cytokine production
    • Peeters AC, Netea MG, Kullberg BJ, Thien T, van der Meer JW. The effect of renin-angiotensin system inhibitors on pro- and anti-inflammatory cytokine production. Immunology 1998; 94: 376-9.
    • (1998) Immunology , vol.94 , pp. 376-379
    • Peeters, A.C.1    Netea, M.G.2    Kullberg, B.J.3    Thien, T.4    van der Meer, J.W.5
  • 87
    • 0031002708 scopus 로고    scopus 로고
    • Angiotensin converting enzyme inhibitors suppress production of tumor necrosis factor-alpha in vitro and in vivo
    • Fukuzawa M, Satoh J, Sagara M, Muto G, Muto Y, Nishimura S, et al. Angiotensin converting enzyme inhibitors suppress production of tumor necrosis factor-alpha in vitro and in vivo. Immunopharmacology 1997; 36:49-55.
    • (1997) Immunopharmacology , vol.36 , pp. 49-55
    • Fukuzawa, M.1    Satoh, J.2    Sagara, M.3    Muto, G.4    Muto, Y.5    Nishimura, S.6
  • 88
    • 0034711678 scopus 로고    scopus 로고
    • Modulation of vascular inflammation in vitro and in vivo by peroxisome proliferator-activated receptor-gamma activators
    • Pasceri V, Wu HD, Willerson JT, Yeh ET. Modulation of vascular inflammation in vitro and in vivo by peroxisome proliferator-activated receptor-gamma activators. Circulation 2000; 101: 235-8.
    • (2000) Circulation , vol.101 , pp. 235-238
    • Pasceri, V.1    Wu, H.D.2    Willerson, J.T.3    Yeh, E.T.4
  • 89
    • 0037031267 scopus 로고    scopus 로고
    • Effect of rosiglitazone treatment on nontraditional markers of cardiovascular disease in patients with type 2 diabetes mellitus
    • Haffner SM, Greenberg AS, Weston WM, Chen H, Williams K, Freed MI. Effect of rosiglitazone treatment on nontraditional markers of cardiovascular disease in patients with type 2 diabetes mellitus. Circulation 2002; 106: 679-84.
    • (2002) Circulation , vol.106 , pp. 679-684
    • Haffner, S.M.1    Greenberg, A.S.2    Weston, W.M.3    Chen, H.4    Williams, K.5    Freed, M.I.6
  • 90
    • 34248371253 scopus 로고    scopus 로고
    • Clinical aspects of platelet inhibitors and thrombus formation
    • Meadows TA, Bhatt DL. Clinical aspects of platelet inhibitors and thrombus formation. Circ Res 2007; 100: 1261-75.
    • (2007) Circ Res , vol.100 , pp. 1261-1275
    • Meadows, T.A.1    Bhatt, D.L.2
  • 91
    • 33846856622 scopus 로고    scopus 로고
    • C-reactive protein (CRP)-lowering agents
    • Prasad K. C-reactive protein (CRP)-lowering agents. Cardiovasc Drug Rev 2006; 24: 33-50.
    • (2006) Cardiovasc Drug Rev , vol.24 , pp. 33-50
    • Prasad, K.1
  • 92
    • 0030803032 scopus 로고    scopus 로고
    • Elevated Chlamydia pneumoniae antibodies, cardiovascular events, and azithromycin in male survivors of myocardial infarction
    • Gupta S, Leatharn EW, Carrington D, Mendall MA, Kaski JC, Camm AJ. Elevated Chlamydia pneumoniae antibodies, cardiovascular events, and azithromycin in male survivors of myocardial infarction. Circulation 1997; 96: 404-7.
    • (1997) Circulation , vol.96 , pp. 404-407
    • Gupta, S.1    Leatharn, E.W.2    Carrington, D.3    Mendall, M.A.4    Kaski, J.C.5    Camm, A.J.6
  • 93
    • 0030845069 scopus 로고    scopus 로고
    • Randomised trial of roxithromycin in non-Q-wave coronary syndromes: ROXIS Pilot Study. ROXIS Study Group
    • Gurfinkel E, Bozovich G, Daroca A, Beek E, Mautner B. Randomised trial of roxithromycin in non-Q-wave coronary syndromes: ROXIS Pilot Study. ROXIS Study Group. Lancet 1997; 350: 404-7.
    • (1997) Lancet , vol.350 , pp. 404-407
    • Gurfinkel, E.1    Bozovich, G.2    Daroca, A.3    Beek, E.4    Mautner, B.5
  • 95
    • 0037426067 scopus 로고    scopus 로고
    • Effect of short-term treatment with azithromycin on recurrent ischaemic events in patients with acute coronary syndrome in the Azithromycin in Acute Coronary Syndrome (AZACS) trial: A randomised controlled trial
    • Cercek B, Shah PK, Noc M, Zahger D, Zeymer U, Matetzky S, et al. Effect of short-term treatment with azithromycin on recurrent ischaemic events in patients with acute coronary syndrome in the Azithromycin in Acute Coronary Syndrome (AZACS) trial: a randomised controlled trial. Lancet 2003; 361: 809-13.
    • (2003) Lancet , vol.361 , pp. 809-813
    • Cercek, B.1    Shah, P.K.2    Noc, M.3    Zahger, D.4    Zeymer, U.5    Matetzky, S.6
  • 97
    • 0141723577 scopus 로고    scopus 로고
    • Azithromycin for the secondary prevention of coronary heart disease events: The WIZARD study: a randomized controlled trial
    • O'Connor CM, Dunne MW, Pfeffer MA, Muhlestein JB, Yao L, Gupta S, et al. Azithromycin for the secondary prevention of coronary heart disease events: the WIZARD study: a randomized controlled trial. JAMA 2003; 290: 1459-66.
    • (2003) JAMA , vol.290 , pp. 1459-1466
    • O'Connor, C.M.1    Dunne, M.W.2    Pfeffer, M.A.3    Muhlestein, J.B.4    Yao, L.5    Gupta, S.6
  • 98
    • 0035936544 scopus 로고    scopus 로고
    • Chlamydia pneumoniae infection in circulating human monocytes is refractory to antibiotic treatment
    • Gieffers J, Fullgraf H, Jahn J, Klinger M, Dalhoff K, Katus HA, et al. Chlamydia pneumoniae infection in circulating human monocytes is refractory to antibiotic treatment. Circulation 2001; 103: 351-6.
    • (2001) Circulation , vol.103 , pp. 351-356
    • Gieffers, J.1    Fullgraf, H.2    Jahn, J.3    Klinger, M.4    Dalhoff, K.5    Katus, H.A.6
  • 99
    • 19944379791 scopus 로고    scopus 로고
    • Effects of Helicobacter pylori eradication on platelet activation and disease recurrence in patients with acute coronary syndromes
    • Elizalde JI, Perez-Pujol S, Heras M, Sionis A, Casanovas N, Martorell T, et al. Effects of Helicobacter pylori eradication on platelet activation and disease recurrence in patients with acute coronary syndromes. Helicobacter 2004; 9: 681-9.
    • (2004) Helicobacter , vol.9 , pp. 681-689
    • Elizalde, J.I.1    Perez-Pujol, S.2    Heras, M.3    Sionis, A.4    Casanovas, N.5    Martorell, T.6
  • 100
    • 33845448235 scopus 로고    scopus 로고
    • Doxycycline affects diet- and bacteria-associated atherosclerosis in an ApoE heterozygote murine model: Cytokine profiling implications
    • Madan M, Bishayi B, Hoge M, Messas E, Amar S. Doxycycline affects diet- and bacteria-associated atherosclerosis in an ApoE heterozygote murine model: cytokine profiling implications. Atherosclerosis 2007; 190: 62-72.
    • (2007) Atherosclerosis , vol.190 , pp. 62-72
    • Madan, M.1    Bishayi, B.2    Hoge, M.3    Messas, E.4    Amar, S.5
  • 101
    • 1842527873 scopus 로고    scopus 로고
    • Clinical and biochemical results of the metalloproteinase inhibition with subantimicrobial doses of doxycycline to prevent acute coronary syndromes (MIDAS) pilot trial
    • Brown DL, Desai KK, Vakili BA, Nouneh C, Lee HM, Golub LM. Clinical and biochemical results of the metalloproteinase inhibition with subantimicrobial doses of doxycycline to prevent acute coronary syndromes (MIDAS) pilot trial. Arterioscler Thromb Vasc Biol 2004; 24: 733-8.
    • (2004) Arterioscler Thromb Vasc Biol , vol.24 , pp. 733-738
    • Brown, D.L.1    Desai, K.K.2    Vakili, B.A.3    Nouneh, C.4    Lee, H.M.5    Golub, L.M.6
  • 102
    • 31344456635 scopus 로고    scopus 로고
    • The importance of estimating the therapeutic index in the development of matrix metalloproteinase inhibitors
    • Peterson JT. The importance of estimating the therapeutic index in the development of matrix metalloproteinase inhibitors. Cardinvasc Res 2006; 69: 677-87.
    • (2006) Cardinvasc Res , vol.69 , pp. 677-687
    • Peterson, J.T.1
  • 103
    • 34248635400 scopus 로고    scopus 로고
    • Is periodontal infection behind the failure of antibiotics to prevent coronary events?
    • Paju S, Sinisalo J, Pussinen PJ, Valtonen V, Nieminen MS. Is periodontal infection behind the failure of antibiotics to prevent coronary events? Atherosclerosis 2006; 193: 193-5.
    • (2006) Atherosclerosis , vol.193 , pp. 193-195
    • Paju, S.1    Sinisalo, J.2    Pussinen, P.J.3    Valtonen, V.4    Nieminen, M.S.5
  • 105
    • 17144463863 scopus 로고    scopus 로고
    • Severe premature coronary artery disease with protease inhibitors
    • Henry K, Melroe H, Ruebsch J, Hermundson J, Levine C, Swensen L, et al. Severe premature coronary artery disease with protease inhibitors. Lancet 1998; 351(9112): 1328.
    • (1998) Lancet , vol.351 , Issue.9112 , pp. 1328
    • Henry, K.1    Melroe, H.2    Ruebsch, J.3    Hermundson, J.4    Levine, C.5    Swensen, L.6
  • 106
    • 0034687601 scopus 로고    scopus 로고
    • Association of influenza vaccination and reduced risk of recurrent myocardial infarction
    • Naghavi M, Barlas Z, Siadaty S, Naguib S, Madjid M, Casscells W. Association of influenza vaccination and reduced risk of recurrent myocardial infarction. Circulation 2000; 102: 3039-45.
    • (2000) Circulation , vol.102 , pp. 3039-3045
    • Naghavi, M.1    Barlas, Z.2    Siadaty, S.3    Naguib, S.4    Madjid, M.5    Casscells, W.6
  • 107
    • 0037417219 scopus 로고    scopus 로고
    • influenza vaccination and reduction in hospitalizations for cardiac disease and stroke among the elderly
    • Nichol KL, Nordin J, Mullooly J, Lask R, Fillbrandt K, Iwane M. influenza vaccination and reduction in hospitalizations for cardiac disease and stroke among the elderly. N Engl J Med 2003; 348: 1322-32.
    • (2003) N Engl J Med , vol.348 , pp. 1322-1332
    • Nichol, K.L.1    Nordin, J.2    Mullooly, J.3    Lask, R.4    Fillbrandt, K.5    Iwane, M.6
  • 109
    • 0037035475 scopus 로고    scopus 로고
    • Influenza vaccine pilot study in acute coronary syndromes and planned percutaneous coronary interventions: The FLU Vaccination Acute Coronary Syndromes (FLUVACS) Study
    • Gurfinkel EP, de la Fuente RL, Mendiz O, Mautner B. Influenza vaccine pilot study in acute coronary syndromes and planned percutaneous coronary interventions: the FLU Vaccination Acute Coronary Syndromes (FLUVACS) Study. Circulation 2002; 105: 2143-7.
    • (2002) Circulation , vol.105 , pp. 2143-2147
    • Gurfinkel, E.P.1    de la Fuente, R.L.2    Mendiz, O.3    Mautner, B.4
  • 110
    • 0036785703 scopus 로고    scopus 로고
    • Influenza vaccination is not associated with a reduction in the risk of recurrent coronary events
    • Jackson LA, Yu O, Heckbert SR, Psaty BM, Malais D, Barlow WE, et al. Influenza vaccination is not associated with a reduction in the risk of recurrent coronary events. Am J Epidemiol 2002; 156: 634-40.
    • (2002) Am J Epidemiol , vol.156 , pp. 634-640
    • Jackson, L.A.1    Yu, O.2    Heckbert, S.R.3    Psaty, B.M.4    Malais, D.5    Barlow, W.E.6
  • 111
    • 0029793720 scopus 로고    scopus 로고
    • Effect of immunization with homologous LDL and oxidized LDL on early atherosclerosis in hypercholesterolemic rabbits
    • Ameli S, Hultgardh-Nilsson A, Regnstrom J, Calara F, Yano J, Cercek B, et al. Effect of immunization with homologous LDL and oxidized LDL on early atherosclerosis in hypercholesterolemic rabbits. Arterioscler Thromb Vasc Biol 1996; 16: 1074-9.
    • (1996) Arterioscler Thromb Vasc Biol , vol.16 , pp. 1074-1079
    • Ameli, S.1    Hultgardh-Nilsson, A.2    Regnstrom, J.3    Calara, F.4    Yano, J.5    Cercek, B.6
  • 112
    • 0031702543 scopus 로고    scopus 로고
    • Immunization of LDL receptor-deficient mice with homologous malondialdehyde-modified and native LDL reduces progression of atherosclerosis by mechanisms other than induction of high titers of antibodies to oxidative neoepitopes
    • Freigang S, Horkko S, Miller E, Witztum JL, Palinski W. Immunization of LDL receptor-deficient mice with homologous malondialdehyde-modified and native LDL reduces progression of atherosclerosis by mechanisms other than induction of high titers of antibodies to oxidative neoepitopes. Arterioscler Thromb Vasc Biol 1998; 18: 1972-82.
    • (1998) Arterioscler Thromb Vasc Biol , vol.18 , pp. 1972-1982
    • Freigang, S.1    Horkko, S.2    Miller, E.3    Witztum, J.L.4    Palinski, W.5
  • 113
    • 0031541903 scopus 로고    scopus 로고
    • Immunization with homologous oxidized low density lipoprotein reduces neointimal formation after balloon injury in hypercholesterolemic rabbits
    • Nilsson J, Calara F, Regnstrom J, Hultgardh-Nilsson A, Ameli S, Cercek B, et al. Immunization with homologous oxidized low density lipoprotein reduces neointimal formation after balloon injury in hypercholesterolemic rabbits. J Am Coll Cardiol 1997; 30: 1886-91.
    • (1997) J Am Coll Cardiol , vol.30 , pp. 1886-1891
    • Nilsson, J.1    Calara, F.2    Regnstrom, J.3    Hultgardh-Nilsson, A.4    Ameli, S.5    Cercek, B.6
  • 114
    • 0028895573 scopus 로고
    • Immunization of low density lipoprotein (LDL) receptor-deficient rabbits with homologous malondialdehyde-modified LDL reduces atherogenesis
    • Palinski W, Miller E, Witzum JL. Immunization of low density lipoprotein (LDL) receptor-deficient rabbits with homologous malondialdehyde-modified LDL reduces atherogenesis. Proc Natl Acad Sci USA 1995; 92: 821-5.
    • (1995) Proc Natl Acad Sci USA , vol.92 , pp. 821-825
    • Palinski, W.1    Miller, E.2    Witzum, J.L.3
  • 115
    • 0035170994 scopus 로고    scopus 로고
    • LDL immunization induces T-cell-dependent antibody formation and protection against atherosclerosis
    • Zhou X, Caligiuri G,Hamsten A, Lefvert AK, Hansson GK. LDL immunization induces T-cell-dependent antibody formation and protection against atherosclerosis. Arterioscler Thromb Vasc Biol 2001; 21: 108-14.
    • (2001) Arterioscler Thromb Vasc Biol , vol.21 , pp. 108-114
    • Zhou, X.1    Caligiuri, G.2    Hamsten, A.3    Lefvert, A.K.4    Hansson, G.K.5
  • 117
    • 0027399854 scopus 로고
    • Association of serum antibodies to heat-shock protein 65 with carotid atherosclerosis
    • Xu Q, Willeit J, Marosi M, Kleindienst R, Oberhollenzer F, Kiechl S, et al. Association of serum antibodies to heat-shock protein 65 with carotid atherosclerosis. Lancet 1993; 341: 255-9.
    • (1993) Lancet , vol.341 , pp. 255-259
    • Xu, Q.1    Willeit, J.2    Marosi, M.3    Kleindienst, R.4    Oberhollenzer, F.5    Kiechl, S.6
  • 118
    • 0037010005 scopus 로고    scopus 로고
    • Oral tolerance with heat shock protein 65 attenuates Mycobacterium tuberculosis-induced and high-fat-diet-driven atherosclerotic lesions
    • Harats D, Yacov N, Gilburd B, Shoenfeld Y, George J. Oral tolerance with heat shock protein 65 attenuates Mycobacterium tuberculosis-induced and high-fat-diet-driven atherosclerotic lesions. J Am Coll Cardiol 2002; 40: 1333-8.
    • (2002) J Am Coll Cardiol , vol.40 , pp. 1333-1338
    • Harats, D.1    Yacov, N.2    Gilburd, B.3    Shoenfeld, Y.4    George, J.5
  • 119
    • 0037167684 scopus 로고    scopus 로고
    • Mucosal administration of heat shock protein-65 decreases atherosclerosis and inflammation in aortic arch of low-density lipoprotein receptor-deficient mice
    • Maron R, Sukhova G, Faria AM, Hoffmann E, Mach F, Libby P, et al. Mucosal administration of heat shock protein-65 decreases atherosclerosis and inflammation in aortic arch of low-density lipoprotein receptor-deficient mice. Circulation 2002; 106: 1708-15.
    • (2002) Circulation , vol.106 , pp. 1708-1715
    • Maron, R.1    Sukhova, G.2    Faria, A.M.3    Hoffmann, E.4    Mach, F.5    Libby, P.6
  • 120
    • 11144224296 scopus 로고    scopus 로고
    • Immunomodulation of atherosclerosis: Implications for vaccine development
    • Nilsson J, Hansson GK, Shah PK. Immunomodulation of atherosclerosis: implications for vaccine development. Arterioscler Thromb Vasc Biol 2005; 25: 18-28.
    • (2005) Arterioscler Thromb Vasc Biol , vol.25 , pp. 18-28
    • Nilsson, J.1    Hansson, G.K.2    Shah, P.K.3
  • 122
    • 0005697467 scopus 로고    scopus 로고
    • Dall JL, Peel A.A. A trial of hydrocartisone in acute myocardial infarction. Lancet 1963; 121097-8.
    • Dall JL, Peel A.A. A trial of hydrocartisone in acute myocardial infarction. Lancet 1963; 121097-8.
  • 123
    • 70449186170 scopus 로고    scopus 로고
    • Treatment of acute myocardial infarction in man with cortisone
    • Gerisch RA, Compeau L. Treatment of acute myocardial infarction in man with cortisone. Am J Cardiol 1958-1: 535-6.
    • Am J Cardiol , vol.1958 -1 , pp. 535-536
    • Gerisch, R.A.1    Compeau, L.2
  • 124
    • 0024518597 scopus 로고
    • Anti-inflammatory drugs in experimental atherosclerosis. 7. Spontaneous atherosclerosis in WHHL rabbits and inhibition by cortisone acetate
    • Makheja AN, Bloom S, Muesing R, Simon T, Bailey JM. Anti-inflammatory drugs in experimental atherosclerosis. 7. Spontaneous atherosclerosis in WHHL rabbits and inhibition by cortisone acetate. Atherosclerosis 1989; 76: 155-61.
    • (1989) Atherosclerosis , vol.76 , pp. 155-161
    • Makheja, A.N.1    Bloom, S.2    Muesing, R.3    Simon, T.4    Bailey, J.M.5
  • 125
    • 0017950650 scopus 로고
    • Long-term preservation of ischemic myocardium after experimental coronary artery occlusion
    • Maclean D, Fishbein MC, Braunwald E, Maroko PR. Long-term preservation of ischemic myocardium after experimental coronary artery occlusion. J Clin Invest 1978; 61: 541-51.
    • (1978) J Clin Invest , vol.61 , pp. 541-551
    • Maclean, D.1    Fishbein, M.C.2    Braunwald, E.3    Maroko, P.R.4
  • 126
    • 2542490375 scopus 로고    scopus 로고
    • Glucocorticoid treatment prevents progressive myocardial dysfunction resulting from experimental coronary microembolization
    • Skyschally A, Haude M, Dorge H, Thielmann M, Duschin A, van de Sand A, et al. Glucocorticoid treatment prevents progressive myocardial dysfunction resulting from experimental coronary microembolization. Circulation 2004; 109: 2337-42.
    • (2004) Circulation , vol.109 , pp. 2337-2342
    • Skyschally, A.1    Haude, M.2    Dorge, H.3    Thielmann, M.4    Duschin, A.5    van de Sand, A.6
  • 127
    • 0015345734 scopus 로고
    • Use of hydrocortisone in the treatment of acute myocardial infarction. Summary of a clinical trial in 446 patients
    • Barzilai D, Plavnick J, Hazani A, Einath R, Kleinhaus N, Kanter Y. Use of hydrocortisone in the treatment of acute myocardial infarction. Summary of a clinical trial in 446 patients. Chest 1972; 61: 488-91.
    • (1972) Chest , vol.61 , pp. 488-491
    • Barzilai, D.1    Plavnick, J.2    Hazani, A.3    Einath, R.4    Kleinhaus, N.5    Kanter, Y.6
  • 128
    • 0015963765 scopus 로고
    • Steroid therapy during acute myocardial infarction. A cause of delayed healing and of ventricular aneurysm
    • Bulkley BH, Roberts WC. Steroid therapy during acute myocardial infarction. A cause of delayed healing and of ventricular aneurysm. Am J Med 1974; 56: 244-50.
    • (1974) Am J Med , vol.56 , pp. 244-250
    • Bulkley, B.H.1    Roberts, W.C.2
  • 129
    • 0017289098 scopus 로고
    • Deleterious effects of methyl- prednisolone in patients with myocardial infraction
    • Roberts R, DeMello V, Sobel BE. Deleterious effects of methyl- prednisolone in patients with myocardial infraction. Circulation 1976; 53(3 Suppl): 1204-6.
    • (1976) Circulation , vol.53 , Issue.3 SUPPL. , pp. 1204-1206
    • Roberts, R.1    DeMello, V.2    Sobel, B.E.3
  • 131
    • 0036820323 scopus 로고    scopus 로고
    • Cardiovascular toxicities of immunosuppressive agents
    • Miller LW. Cardiovascular toxicities of immunosuppressive agents. Am J Transplant 2002; 2: 807-18.
    • (2002) Am J Transplant , vol.2 , pp. 807-818
    • Miller, L.W.1
  • 132
    • 33847723010 scopus 로고    scopus 로고
    • Unanswered questions-drug-eluting stents and the risk of late thrombosis
    • Maisel WH. Unanswered questions-drug-eluting stents and the risk of late thrombosis. N Engl J Med 2007; 356: 981-4.
    • (2007) N Engl J Med , vol.356 , pp. 981-984
    • Maisel, W.H.1
  • 133
    • 33644872364 scopus 로고    scopus 로고
    • ACC/AHA/SCAI 2005 Guideline Update for Percutaneous Coronary Intervention-summary article: A report of the American College of Cardiology/American Heart Association Task Force on Practice Guidelines (ACC/AHA/SCAI Writing Committee to Update the 2001 Guidelines for Percutaneous Coronary Intervention)
    • Smith SC Jr, Feldman TE, Hirshfeld JW Jr, Jacobs AK, Kern MJ, King SB 3rd, et al. ACC/AHA/SCAI 2005 Guideline Update for Percutaneous Coronary Intervention-summary article: a report of the American College of Cardiology/American Heart Association Task Force on Practice Guidelines (ACC/AHA/SCAI Writing Committee to Update the 2001 Guidelines for Percutaneous Coronary Intervention). Circulation 2006; 113: 156-75.
    • (2006) Circulation , vol.113 , pp. 156-175
    • Smith Jr, S.C.1    Feldman, T.E.2    Hirshfeld Jr, J.W.3    Jacobs, A.K.4    Kern, M.J.5    King 3rd, S.B.6
  • 134
    • 0032499629 scopus 로고    scopus 로고
    • Myocardial infarction and apoptosis after myocardial ischemia and reperfusion: Role of the terminal complement components and inbibition by anti-C5 therapy
    • Vakeva AP, Agah A, Rollins SA, Matis LA, Li L, Stahl GL. Myocardial infarction and apoptosis after myocardial ischemia and reperfusion: role of the terminal complement components and inbibition by anti-C5 therapy. Circulation 1998; 97: 2259-67.
    • (1998) Circulation , vol.97 , pp. 2259-2267
    • Vakeva, A.P.1    Agah, A.2    Rollins, S.A.3    Matis, L.A.4    Li, L.5    Stahl, G.L.6
  • 135
    • 0041732120 scopus 로고    scopus 로고
    • Effect of pexelizumab, an anti-C5 complement intibody, as adjunctive therapy to fibrinolysis in acute myocardial infarction the COMPlement inhibition in myocardial infarction treated with thromboLYtics (COMPLY) trial
    • Mahaffey KW, Granger CB, Nicolau JC, Ruzyllo W, Weaver WD, Theroux P, et al. Effect of pexelizumab, an anti-C5 complement intibody, as adjunctive therapy to fibrinolysis in acute myocardial infarction the COMPlement inhibition in myocardial infarction treated with thromboLYtics (COMPLY) trial. Circulation 2003; 108: 1176-83.
    • (2003) Circulation , vol.108 , pp. 1176-1183
    • Mahaffey, K.W.1    Granger, C.B.2    Nicolau, J.C.3    Ruzyllo, W.4    Weaver, W.D.5    Theroux, P.6
  • 136
    • 33845981823 scopus 로고    scopus 로고
    • Pexelizumab for acute ST-elevation myocardial infarction in patients undergoing primary percutaneous coronary intervention: A randomized controlled trial
    • Armstrong PW, Granger CB, Adams PX, Hamm C, Holmes D Jr, O'Neill WW, et al. Pexelizumab for acute ST-elevation myocardial infarction in patients undergoing primary percutaneous coronary intervention: a randomized controlled trial. JAMA 2007; 297: 43-51.
    • (2007) JAMA , vol.297 , pp. 43-51
    • Armstrong, P.W.1    Granger, C.B.2    Adams, P.X.3    Hamm, C.4    Holmes Jr, D.5    O'Neill, W.W.6
  • 137
    • 33746043365 scopus 로고    scopus 로고
    • Pexelizurnab reduces death and myocardial infarction in higher risk cardiac surgical patients
    • Haverich A, Sheman SK, Levy JH, Chen JC, Carrier M, Taylor KM, et al. Pexelizurnab reduces death and myocardial infarction in higher risk cardiac surgical patients. Ann Thorac Surg 2006; 82: 486-92.
    • (2006) Ann Thorac Surg , vol.82 , pp. 486-492
    • Haverich, A.1    Sheman, S.K.2    Levy, J.H.3    Chen, J.C.4    Carrier, M.5    Taylor, K.M.6
  • 138
    • 33644872282 scopus 로고    scopus 로고
    • Toll-like receptor therapies compete to reduce side effects
    • Schmidt C. Toll-like receptor therapies compete to reduce side effects. Nat Biotechnol. 2006; 24: 20-1.
    • (2006) Nat Biotechnol , vol.24 , pp. 20-21
    • Schmidt, C.1
  • 139
    • 3142713223 scopus 로고    scopus 로고
    • Inhibition of endotoxin response by synthetic TLR4 antagonists
    • Hawkins LD, Christ WJ, Rossignol DP. Inhibition of endotoxin response by synthetic TLR4 antagonists. Curr Top Med Chem 2004; 4: 1147-71.
    • (2004) Curr Top Med Chem , vol.4 , pp. 1147-1171
    • Hawkins, L.D.1    Christ, W.J.2    Rossignol, D.P.3
  • 141
    • 33745003883 scopus 로고    scopus 로고
    • BrugalettaS,Re-buzziA, Biasucci,Crea F. Modulation of CD4(+)CD28null T lymphocytes by tumor necrosis factor-alpha blockade in patients with unstable angina
    • Rizzello V, LiuzzonG BrugalettaS,Re-buzziA, Biasucci,Crea F. Modulation of CD4(+)CD28null T lymphocytes by tumor necrosis factor-alpha blockade in patients with unstable angina. Circulation 2006; 113: 2272-7.
    • (2006) Circulation , vol.113 , pp. 2272-2277
    • Rizzello, V.1    Liuzzon, G.2
  • 142
    • 0035957036 scopus 로고    scopus 로고
    • Results of targeted anti-tumor necrosis factor therapy with etanercept (ENBREL) in patients with advanced heart failure
    • Bozkurt B, Torre-Amione G, Warren MS, Whitmore J, Soran OZ, Feldman AM, et al. Results of targeted anti-tumor necrosis factor therapy with etanercept (ENBREL) in patients with advanced heart failure. Circulation 2001; 103: 1044-7.
    • (2001) Circulation , vol.103 , pp. 1044-1047
    • Bozkurt, B.1    Torre-Amione, G.2    Warren, M.S.3    Whitmore, J.4    Soran, O.Z.5    Feldman, A.M.6
  • 143
    • 0037195727 scopus 로고    scopus 로고
    • Inflammatory mediators and the failing heart: Past, present, and the foreseeable future
    • Mann DL. Inflammatory mediators and the failing heart: past, present, and the foreseeable future. Circ Res 2002; 91: 988-98.
    • (2002) Circ Res , vol.91 , pp. 988-998
    • Mann, D.L.1
  • 144
    • 0034909511 scopus 로고    scopus 로고
    • Freunds adjuvant alone is antiatherogenic in apoE-deficient mice and specific immunization against TNFalpha confers no additional benefit
    • Hansen PR, Chew M, Zhou J, Daugherty A, Heegaard N, Jensen P, et al. Freunds adjuvant alone is antiatherogenic in apoE-deficient mice and specific immunization against TNFalpha confers no additional benefit. Atherosclerosis 2001; 158: 87-94.
    • (2001) Atherosclerosis , vol.158 , pp. 87-94
    • Hansen, P.R.1    Chew, M.2    Zhou, J.3    Daugherty, A.4    Heegaard, N.5    Jensen, P.6
  • 145
    • 5444224197 scopus 로고    scopus 로고
    • Effect of anti TNFalpha therapy on arterial diameter and wall shear stress and HDL cholesterol
    • Irace C, Mancuso G, Fiaschi E, Madia A, Sesti G, Gnasso A. Effect of anti TNFalpha therapy on arterial diameter and wall shear stress and HDL cholesterol. Atherosclerosis 2004; 177: 113-8.
    • (2004) Atherosclerosis , vol.177 , pp. 113-118
    • Irace, C.1    Mancuso, G.2    Fiaschi, E.3    Madia, A.4    Sesti, G.5    Gnasso, A.6
  • 146
    • 2642608661 scopus 로고    scopus 로고
    • Reduction of atherosclerosis in mice by inhibition of CD40 signalling
    • Mach F, Schonbeck U, Sukhova GK, Atkinson E, Libby P. Reduction of atherosclerosis in mice by inhibition of CD40 signalling. Nature 1998; 394: 200-3.
    • (1998) Nature , vol.394 , pp. 200-203
    • Mach, F.1    Schonbeck, U.2    Sukhova, G.K.3    Atkinson, E.4    Libby, P.5
  • 147
    • 21344454903 scopus 로고    scopus 로고
    • Platelet activation and the CD40/CD40 ligand pathway: Mechanisms and implications for human disease
    • Danese S, Fiocchi C. Platelet activation and the CD40/CD40 ligand pathway: mechanisms and implications for human disease. Crit Rev Immunol 2005; 25: 103-121.
    • (2005) Crit Rev Immunol , vol.25 , pp. 103-121
    • Danese, S.1    Fiocchi, C.2
  • 148
    • 33750542135 scopus 로고    scopus 로고
    • Toll' gates for future immunotherapy
    • Ishii KJ, Uematsu S, Akira S. 'Toll' gates for future immunotherapy. Curr Pharm Des 2006; 12(32): 4135-42.
    • (2006) Curr Pharm Des , vol.12 , Issue.32 , pp. 4135-4142
    • Ishii, K.J.1    Uematsu, S.2    Akira, S.3
  • 149
    • 34248218626 scopus 로고    scopus 로고
    • Jukema Chemokines and atherosclerotic plaque progression: Towards therapeutic targeting?
    • Kraaijeveld AO, de lager SC, van Berkel TJ, Biessen EA, Jukema Chemokines and atherosclerotic plaque progression: towards therapeutic targeting? Curr Pharm Des 2007; 13(10): 1039-52.
    • (2007) Curr Pharm Des , vol.13 , Issue.10 , pp. 1039-1052
    • Kraaijeveld, A.O.1    de lager, S.C.2    van Berkel, T.J.3    Biessen, E.A.4
  • 150
    • 33750537650 scopus 로고    scopus 로고
    • Endotoxin, TLR4 signaling and vascular inflammation: Potential therapeutic targets in cardiovascular disease
    • Stoll LL, Denning GM, Weintraub NL. Endotoxin, TLR4 signaling and vascular inflammation: potential therapeutic targets in cardiovascular disease. Curr Pharm Des 2006; 12(32): 4229-45.
    • (2006) Curr Pharm Des , vol.12 , Issue.32 , pp. 4229-4245
    • Stoll, L.L.1    Denning, G.M.2    Weintraub, N.L.3


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