Synergistic effects of MAP2 and MAP1B knockout in neuronal migration, dendritic outgrowth, and microtubule organization

Journal of Cell Biology

Volumn 155, Issue 1, 2001, Pages 65-76

  Teng, Junlin ^a   Takei, Yosuke ^a   Harada, Akihiro ^a   Nakata, Takao ^a   Chen, Jianguo ^a   Hirokawa, Nobutaka ^a  

^a UNIVERSITY OF TOKYO   (Japan)

Author keywords

Dendrite; MAP1B; MAP2; Microtubule; Neuronal migration

Indexed keywords

MICROTUBULE ASSOCIATED PROTEIN 2; MICROTUBULE ASSOCIATED PROTEIN 5;

ANIMAL CELL; ANIMAL TISSUE; ARTICLE; CELL MIGRATION; CELL VACUOLE; DENDRITE; EMBRYO; GROWTH CONE; HIPPOCAMPUS; INTRACELLULAR TRANSPORT; KNOCKOUT GENE; KNOCKOUT MOUSE; MICROTUBULE; MORPHOGENESIS; MOUSE; NERVE CELL; NERVE CELL DIFFERENTIATION; NERVE FIBER GROWTH; NEUROPATHOLOGY; NONHUMAN; PRIORITY JOURNAL; SURVIVAL;

ANIMALS; ANIMALS, NEWBORN; AXONAL TRANSPORT; AXONS; CELL MOVEMENT; CELLS, CULTURED; CEREBRAL CORTEX; DENDRITES; GENE TARGETING; GENES, REPORTER; HIPPOCAMPUS; IMMUNOHISTOCHEMISTRY; MICE; MICE, KNOCKOUT; MICROTUBULE-ASSOCIATED PROTEINS; MICROTUBULES; NEURONS; RECOMBINANT FUSION PROTEINS;

ANIMALIA;

EID: 0035494477     PISSN: 00219525     EISSN: None     Source Type: Journal    
DOI: 10.1083/jcb.200106025     Document Type: Article

References (49)

1. Thalamocortical axons extend along a chondroitin sulfate proteoglycan-enriched pathway coincident with the neocorticaI subplate and distinct from the efferent path
2. Expression and distribution of phosphorylated MAP1B in growing axons of cultured hippocampal neurons
3. Attenuation of microtubule-associated protein 1B expression by antisense oligodeoxynucleotides inhibits initiation of neurite outgrowth
4. Suppression of MAP2 in cultured cerebellar macroneurons inhibits minor neurite formation
5. Mice lacking p35, a neuronal specific activator of Cdk5, display cortical lamination defects, seizures, and adult lethality
6. Projection domains of MAP2 and tau determine spacings between microtubules in dendrites and axons
7. Microtubule-associated protein 2c reorganizes both microtubules and microfilaments into distinct cytological structures in an actin-binding protein-280-deficient melanoma cell line
8. Doublecortin is the major gene causing X-linked subcortical laminar heteroropia (SCLH)
9. Neuronal abnormalities in microtubule-associated protein 1B mutant mice
10. Doublecortin is a developmentally regulated, microtubule-associated protein expressed in migrating and differentiating neurons
11. Going new places using an old MAP: Tau, microtubules and human neurodegenerative disease
12. Doublecortin, a brain-specific gene mutated in human X-linked lissencephaly and double cortex syndrome, encodes a putative signaling
13. Doublecortin is a microtubule-associated protein and is expressed widely by migrating neurons
14. Events governing organization of postmigratory neurons: Studies on brain development in normal and reeler mice
15. Perinatal lethality of microtubule-associated protein 1B-deficient mice expressing alternative isoforms of the protein at low levels
16. Rat hippocampal neurons in low-density culture
17. Dynamic behaviors of growth cones extending in the corpus callosum of living cortical brain slices observed with video microscopy
18. Altered microtubule organization in small-calibre axons of mice lacking tau protein
19. Molecular architecture and dynamics of the neuronal cytoskeleton
20. Microtubule organization and dynamics dependent on microtubule-associated proteins
21. Graded reduction of Pafahlbl (LisI) activity results in neuronal migration defects and early embryonic lethality
22. Localization of specific epitopes on human microtubule-associated protein 2
23. Genomic structure of human microtubule-associated protein 2 (MAP-2) and characterization of additional MAP-2 isoforms
24. MAP1B is required for axon guidance and is involved in the development of the central and peripheral nervous system
25. Identification of radial glial cells within the developing murine central nervous system: Studies based upon a new histochemical marker
26. Visualization of the dynamics of synaptic vesicle and plasma membrane proteins in living axons
27. The microtubule binding domain of microtubule-associated protein MAP1B contains a repeated sequence motif unrelated to that of MAP2 and tau
28. Targeted disruption of the cyclin-dependent kinase 5 gene results in abnormal corticogenesis, neuronal pathology and perinatal death
29. Evidence for the participation of the neuron-specific CDK5 activator P35 during laminin-enhanced axonal growth
30. Specification of cerebral cortical areas
31. Polarity of microtubule assemblies during neuronal cell migration
32. Isolation of a Miller-Dieker lissencephaly gene containing G protein, beta-subunit-like repeats
33. Phosphorylation of microtubule-associated protein 2 (MAP2) and its relevance for the regulation of the neuronal cytoskeleton function
34. Reduction of microtubule catastrophe events by LISI, platelet-activating factor acetylhydrolase subunit
35. Microtubule-associated protein 1B: Molecular structure, localization, and phosphorylation-dependent expression in developing neurons
36. Antisense MAP-2 oligonucleotides induce changes in microtubule assembly and neuritic elongation in pre-existing neurites of rat cortical neurons
37. Scrambler and yorari disrupt the disabled gene and produce a reeler-like phenotype in mice
38. Axonal growth-associated proteins
39. BUdR as an S-phase marker for quantitative studies of cytokinetic behaviour in the murine cerebral ventricular zone
40. Delayed development of nervous system in mice homozygous for disrupted microtubule-associated protein 1B (MAP1B) gene
41. Defects in axonal elongation and neuronal migration in mice with disrupted tau and map1b genes
42. Microtubule behavior in the growth cones of living neurons during axon elongation
43. Making connection: Cytoskeletal rearrangements duting growth cone guidance
44. Novel features of the light chain of microtubule-associated protein MAP1B: Microtubule stabilization, self-interaction, actin filament binding, and regularion by heavy chain
45. Reeler/disabled-like disruption of neuronal migration in knockout mice lacking the VLDL receptor and ApoE receptor 2
46. Novel organization of microtubules in cultured central nervous system neurons: Formation of haitpin loops at ends of maturing neurites
47. The roles of microtubule-associated proteins in brain morphogenesis: A review
48. Depletion of casein kinase II by antisense oligonucleotide prevents neuritogenesis in neuroblastoma cells
49. A novel neurological mutant mouse, yotari, which exhibits reeler-like phenotype but expresses CR-50 antigen/ reelin