메뉴 건너뛰기




Volumn 40, Issue 3, 1998, Pages 272-285

Molecular and functional characteristics of MAP-2a: Ability of MAP-2a versus MAP-2b to induce stable microtubules in COS cells

Author keywords

Acetylated tubulin; MAP 2 isoforms; MAP 2a; MAP 2b; Microtubule bundling; Microtubules; Nocodazole; Transient transfections

Indexed keywords

MICROTUBULE ASSOCIATED PROTEIN 2; NOCODAZOLE;

EID: 0031747115     PISSN: 08861544     EISSN: None     Source Type: Journal    
DOI: 10.1002/(SICI)1097-0169(1998)40:3<272::AID-CM6>3.0.CO;2-F     Document Type: Article
Times cited : (31)

References (33)
  • 1
    • 0027723742 scopus 로고
    • Characterization of the transcripts encoding two isoforms of human microtubule-associated protein-2 (MAP-2)
    • Albala, J.S., Kalcheva, N., and Shafit-Zagardo, B. (1993): Characterization of the transcripts encoding two isoforms of human microtubule-associated protein-2 (MAP-2). Gene 136:377-378.
    • (1993) Gene , vol.136 , pp. 377-378
    • Albala, J.S.1    Kalcheva, N.2    Shafit-Zagardo, B.3
  • 2
    • 0028997083 scopus 로고
    • Human microtubule-associated protein-2c localizes to dendrites and axons in fetal spinal motor neurons
    • Abala, J.S., Kress, Y., Liu, W-K., Weidenheim, K., Yen, S-H., and Shafit-Zagardo, B. (1995): Human microtubule-associated protein-2c localizes to dendrites and axons in fetal spinal motor neurons. J. Neurochem. 64:2480-2490.
    • (1995) J. Neurochem. , vol.64 , pp. 2480-2490
    • Abala, J.S.1    Kress, Y.2    Liu, W.-K.3    Weidenheim, K.4    Yen, S.-H.5    Shafit-Zagardo, B.6
  • 3
    • 0028282932 scopus 로고
    • Phosphorylation of microtubule-associated proteins MAP-2a, b and MAP-2c at Ser 136 by proline-directed kinases in vivo and in vitro
    • Berling, B., Wille, H., Roll, B., Mandelkow, E. M., Garner, C., and Mandelkow, E. (1994): Phosphorylation of microtubule-associated proteins MAP-2a, b and MAP-2c at Ser 136 by proline-directed kinases in vivo and in vitro. Eur. J. Cell Biol. 64:120-130.
    • (1994) Eur. J. Cell Biol. , vol.64 , pp. 120-130
    • Berling, B.1    Wille, H.2    Roll, B.3    Mandelkow, E.M.4    Garner, C.5    Mandelkow, E.6
  • 4
    • 0026729767 scopus 로고
    • Projection domains of MAP-2 and tau determine the spacing between microtubules in dendrites and axons
    • Chen, J., Kanai, Y., Cowan, N., and Hirokawa, N. (1992): Projection domains of MAP-2 and tau determine the spacing between microtubules in dendrites and axons. Nature 360:674-677.
    • (1992) Nature , vol.360 , pp. 674-677
    • Chen, J.1    Kanai, Y.2    Cowan, N.3    Hirokawa, N.4
  • 5
    • 0006227378 scopus 로고    scopus 로고
    • MAP-2a an alternatively spliced variant of microtubule-associated protein 2
    • Chung, W.J., Kindler, S., Seidenbecher, C., and Garner, C.C. (1996): MAP-2a an alternatively spliced variant of microtubule-associated protein 2. J. Neurochem. 66:1273-1281.
    • (1996) J. Neurochem. , vol.66 , pp. 1273-1281
    • Chung, W.J.1    Kindler, S.2    Seidenbecher, C.3    Garner, C.C.4
  • 6
    • 0029977256 scopus 로고    scopus 로고
    • MAP2 are preferentially expressed in the spinal cord
    • Couchie, D., Chabas, S., Mavilia, C., and Nunez, J. (1996): MAP2 are preferentially expressed in the spinal cord. FEBS Lett. 388:76-79.
    • (1996) FEBS Lett. , vol.388 , pp. 76-79
    • Couchie, D.1    Chabas, S.2    Mavilia, C.3    Nunez, J.4
  • 7
    • 0024801318 scopus 로고
    • Sequence of a human MAP-2 region sharing epitopes with Alzheimer neurofibrillary tangles
    • Dammerman, M., Yen, S.-H., and Shafit-Zagardo, B. (1989): Sequence of a human MAP-2 region sharing epitopes with Alzheimer neurofibrillary tangles. J. Neurosci. Res. 24:487-495.
    • (1989) J. Neurosci. Res. , vol.24 , pp. 487-495
    • Dammerman, M.1    Yen, S.-H.2    Shafit-Zagardo, B.3
  • 8
    • 0027519666 scopus 로고
    • An isoform of microtubule-associated protein 2 (MAP-2) containing four repeats of the tubulin-binding motif
    • Doll, T., Meichsner, M., Riederer, B.M., Honneger, P., and Matus, A. (1993): An isoform of microtubule-associated protein 2 (MAP-2) containing four repeats of the tubulin-binding motif. J. Cell Sci. 106:633-640.
    • (1993) J. Cell Sci. , vol.106 , pp. 633-640
    • Doll, T.1    Meichsner, M.2    Riederer, B.M.3    Honneger, P.4    Matus, A.5
  • 10
    • 0024573607 scopus 로고
    • Establishment of a stable, acetylated microtubule bundles during neuronal commitment
    • Falconer, M.M., Vielkind, U., and Brown, D.L. (1989): Establishment of a stable, acetylated microtubule bundles during neuronal commitment. Cell Motil. Cytoskel. 12:169-180.
    • (1989) Cell Motil. Cytoskel. , vol.12 , pp. 169-180
    • Falconer, M.M.1    Vielkind, U.2    Brown, D.L.3
  • 11
    • 0030228573 scopus 로고    scopus 로고
    • Four repeat high-mol-wt MAP2 forms in rat dorsal root ganglia
    • Forleo, P., Couchie, D., Chabas, S., and Nunez, J. (1996): Four repeat high-mol-wt MAP2 forms in rat dorsal root ganglia. J. Mol. Neurosci. 7:193-201.
    • (1996) J. Mol. Neurosci. , vol.7 , pp. 193-201
    • Forleo, P.1    Couchie, D.2    Chabas, S.3    Nunez, J.4
  • 12
    • 0028827092 scopus 로고
    • Identification of new exon of the brain microtubule-associated protein 2
    • Guilleminot, J., Langkopf, A., Nunez, J. (1995): Identification of new exon of the brain microtubule-associated protein 2. C.R. Acad. Sci. Paris 318:959-964.
    • (1995) C.R. Acad. Sci. Paris , vol.318 , pp. 959-964
    • Guilleminot, J.1    Langkopf, A.2    Nunez, J.3
  • 13
    • 0028153172 scopus 로고
    • Localization of specific epitopes on human microtubule-associated protein 2
    • Kalcheva, N., Albala, J.S., Binder, L.I., and Shafit-Zagardo, B. (1994): Localization of specific epitopes on human microtubule-associated protein 2. J. Neurochem. 63:2336-2341.
    • (1994) J. Neurochem. , vol.63 , pp. 2336-2341
    • Kalcheva, N.1    Albala, J.S.2    Binder, L.I.3    Shafit-Zagardo, B.4
  • 14
    • 0029166735 scopus 로고
    • Three unique 5′ untranslated regions are spliced to common coding exons of high- and low-molecular-weight microtubule-associated protein-2
    • Kalcheva, N., and Shafit-Zagardo, B. (1995a): Three unique 5′ untranslated regions are spliced to common coding exons of high- and low-molecular-weight microtubule-associated protein-2. J. Neurochem. 65:1472-1480.
    • (1995) J. Neurochem. , vol.65 , pp. 1472-1480
    • Kalcheva, N.1    Shafit-Zagardo, B.2
  • 15
    • 0028793125 scopus 로고
    • Genomic structure of human microtubule-associated protein 2 (MAP-2) and characterization of additional MAP-2 isoforms
    • Kalcheva, N., Albala, J.S., O'Guin, K., Rubino, H., Garner, G., and Shatit-Zagardo, B. (1995b): Genomic structure of human microtubule-associated protein 2 (MAP-2) and characterization of additional MAP-2 isoforms. Proc. Natl. Acad. Sci. U.S.A. 92:10894-10898.
    • (1995) Proc. Natl. Acad. Sci. U.S.A. , vol.92 , pp. 10894-10898
    • Kalcheva, N.1    Albala, J.S.2    O'Guin, K.3    Rubino, H.4    Garner, G.5    Shatit-Zagardo, B.6
  • 16
    • 0031037198 scopus 로고    scopus 로고
    • Expression of microtubule-associated protein-2a and other novel microtubule-associated protein-2 transcripts in human fetal spinal cord
    • Kalcheva, N., Weidenheim, K.M., Kress, Y., and Shafit-Zagardo, B. (1997): Expression of microtubule-associated protein-2a and other novel microtubule-associated protein-2 transcripts in human fetal spinal cord. J. Neurochem, 68:383-391.
    • (1997) J. Neurochem , vol.68 , pp. 383-391
    • Kalcheva, N.1    Weidenheim, K.M.2    Kress, Y.3    Shafit-Zagardo, B.4
  • 17
    • 0018332641 scopus 로고
    • The periodic association of MAP-2 with brain microtubules in vitro
    • Kim, H., Binder, L.I., and Rosenbaum, J.L. (1979): The periodic association of MAP-2 with brain microtubules in vitro. J. Cell Biol. 80:266-276.
    • (1979) J. Cell Biol. , vol.80 , pp. 266-276
    • Kim, H.1    Binder, L.I.2    Rosenbaum, J.L.3
  • 18
    • 0028027393 scopus 로고
    • Four repeat MAP2 isoforms in human and rat brain
    • Kindler, S., and Garner, C.C. (1994): Four repeat MAP2 isoforms in human and rat brain. Mol. Brain Res. 26:218-224.
    • (1994) Mol. Brain Res. , vol.26 , pp. 218-224
    • Kindler, S.1    Garner, C.C.2
  • 19
    • 0025278299 scopus 로고
    • Complete cDNA sequence encoding rat high and low molecular weight MAP-2
    • Kindler, S., Schwanke, B., Schulz, B., and Garner, C.C. (1990): Complete cDNA sequence encoding rat high and low molecular weight MAP-2. Nucleic Acids Res. 18:2822.
    • (1990) Nucleic Acids Res. , vol.18 , pp. 2822
    • Kindler, S.1    Schwanke, B.2    Schulz, B.3    Garner, C.C.4
  • 20
    • 0024109687 scopus 로고
    • Epitopes that span the tau molecule are shared with paired helical filaments
    • Kosik, K.S., Orecchio, L.O., Binder, L.,I., Trojanowski, J.Q., Lee, V., M-Y., and Lee, G. (1988): Epitopes that span the tau molecule are shared with paired helical filaments. Neuron 1:817-825.
    • (1988) Neuron , vol.1 , pp. 817-825
    • Kosik, K.S.1    Orecchio, L.O.2    Binder, L.I.3    Trojanowski, J.Q.4    Lee, V.5    M-Y6    Lee, G.7
  • 21
    • 0014949207 scopus 로고
    • Cleavage of structural proteins during the assembly of the head of bacteriophage T4
    • Laemmli, U.K. (1970): Cleavage of structural proteins during the assembly of the head of bacteriophage T4. Nature 227:680-685.
    • (1970) Nature , vol.227 , pp. 680-685
    • Laemmli, U.K.1
  • 22
    • 0026670808 scopus 로고
    • Microtubule-bundling studies revised: Is there a role for MAP-2?
    • Lee, G., and Brandt, R. (1992): Microtubule-bundling studies revised: Is there a role for MAP-2? Trends Cell Biol. 2:286-289.
    • (1992) Trends Cell Biol. , vol.2 , pp. 286-289
    • Lee, G.1    Brandt, R.2
  • 23
    • 0024326799 scopus 로고
    • Organization of microtubules in dendriles und axons is determined a short hydrophobic zipper in microtubule-associated proteins MAP-2 and tau
    • Lewis, S.A., Ivanov, I. E., Lee, G-H., and Cowan, N.J. (1989): Organization of microtubules in dendriles und axons is determined a short hydrophobic zipper in microtubule-associated proteins MAP-2 and tau. Nature 342:498-505.
    • (1989) Nature , vol.342 , pp. 498-505
    • Lewis, S.A.1    Ivanov, I.E.2    Lee, G.-H.3    Cowan, N.J.4
  • 24
    • 0025082438 scopus 로고
    • Microtubule-associated proteins
    • Matus, A. (1990): Microtubule-associated proteins. Cur. Opin. Cell Biol. 2:10-14.
    • (1990) Cur. Opin. Cell Biol. , vol.2 , pp. 10-14
    • Matus, A.1
  • 25
    • 0024761741 scopus 로고
    • The RII subunit of cAMP-dependent protein kinase binds to a common amino-terminal domain in microtubule associated proteins 2A, 2B and 2C
    • Obar, R.A., Dingus, J., Baylay, H., and Valee, R.B. (1989): The RII subunit of cAMP-dependent protein kinase binds to a common amino-terminal domain in microtubule associated proteins 2A, 2B and 2C. Neuron 3:639-645.
    • (1989) Neuron , vol.3 , pp. 639-645
    • Obar, R.A.1    Dingus, J.2    Baylay, H.3    Valee, R.B.4
  • 26
    • 0024346422 scopus 로고
    • Embryonic MAP-2 lacks the cross-linking sidearm sequences and dendritic targeting signal of adult MAP-2
    • Papandrikopoulou, A., Doll, T., Tucker, R.P., Garner, C.C., and Matus, A (1990): Embryonic MAP-2 lacks the cross-linking sidearm sequences and dendritic targeting signal of adult MAP-2. Nature 340:650-652.
    • (1990) Nature , vol.340 , pp. 650-652
    • Papandrikopoulou, A.1    Doll, T.2    Tucker, R.P.3    Garner, C.C.4    Matus, A.5
  • 27
    • 0024410833 scopus 로고
    • MAP 1A and MAP 1B are structurally related microtubule associated proteins with distinct developmental patterns in the CNS
    • Schoenfeld, T.A., McKerracher, L., Obar, R., Vallee, R.B. (1989): MAP 1A and MAP 1B are structurally related microtubule associated proteins with distinct developmental patterns in the CNS. J. Neurosci. 9:1712-1730.
    • (1989) J. Neurosci. , vol.9 , pp. 1712-1730
    • Schoenfeld, T.A.1    McKerracher, L.2    Obar, R.3    Vallee, R.B.4
  • 28
    • 0024221264 scopus 로고
    • Astrocytes regulate GFAP mRNA levels by cyclic AMP and protein kinase-C-dependent mechanism
    • Shafit-Zagardo, B., Kume-Iwaki, A., and Goldman, J.E. (1989): Astrocytes regulate GFAP mRNA levels by cyclic AMP and protein kinase-C-dependent mechanism. Glia 1: 346-354.
    • (1989) Glia , vol.1 , pp. 346-354
    • Shafit-Zagardo, B.1    Kume-Iwaki, A.2    Goldman, J.E.3
  • 29
    • 0031030967 scopus 로고    scopus 로고
    • Distribution and subcellular localization of high molecular weight microtubule-associated protein-2 expressing exon 8 in brain and spinal cord
    • Shafit-Zagardo, B., Kalcheva, N., Dickson, D., Davies, P., and Kress, Y. (1997): Distribution and subcellular localization of high molecular weight microtubule-associated protein-2 expressing exon 8 in brain and spinal cord. J. Neurochem. 68:862-873.
    • (1997) J. Neurochem. , vol.68 , pp. 862-873
    • Shafit-Zagardo, B.1    Kalcheva, N.2    Dickson, D.3    Davies, P.4    Kress, Y.5
  • 30
    • 0031853417 scopus 로고    scopus 로고
    • Making sense of the multiple MAP-2 transcripts and their role in the neuron
    • Shafit-Zagardo, B., and Kalcheva, N. (1998): Making sense of the multiple MAP-2 transcripts and their role in the neuron. Mol. Neurobiol. 16(2):149-162.
    • (1998) Mol. Neurobiol. , vol.16 , Issue.2 , pp. 149-162
    • Shafit-Zagardo, B.1    Kalcheva, N.2
  • 31
    • 0009482260 scopus 로고
    • Electrophoretic transfer of proteins from polyacrylamide gels to nitrocellulose sheets: Procedure and some applications
    • Towbin, H., Staehelin, T., and Gordon, J. (1979): Electrophoretic transfer of proteins from polyacrylamide gels to nitrocellulose sheets: Procedure and some applications. Proc. Natl. Acad. Sci. U.S.A. 76:4350-4354.
    • (1979) Proc. Natl. Acad. Sci. U.S.A. , vol.76 , pp. 4350-4354
    • Towbin, H.1    Staehelin, T.2    Gordon, J.3
  • 32
    • 0020183553 scopus 로고
    • Electron microscopy of MAP2 (microtubule-associated protein 2)
    • Voter, W.A., and Erickson, H.P. (1982): Electron microscopy of MAP2 (microtubule-associated protein 2). J Ultrastruct. Res. 80:374-382.
    • (1982) J Ultrastruct. Res. , vol.80 , pp. 374-382
    • Voter, W.A.1    Erickson, H.P.2
  • 33
    • 0024209675 scopus 로고
    • Complete sequence of a cDNA encoding mouse MAP2
    • Wang, D., Lewis, S.A., and Cowan, N.J. (1988): Complete sequence of a cDNA encoding mouse MAP2. Nucleic Acids Res. 16, 11369.
    • (1988) Nucleic Acids Res. , vol.16 , pp. 11369
    • Wang, D.1    Lewis, S.A.2    Cowan, N.J.3


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.