Injectable Biodegradable Systems

Biodegradable Systems in Tissue Engineering and Regenerative Medicine

Volumn , Issue , 2004, Pages 13-28

  Boesel, L F ^a   Reis, Rui L ^a  

^a UNIVERSITY OF MINHO   (Portugal)

Author keywords

[No Author keywords available]

Indexed keywords

EID: 37349082947     PISSN: None     EISSN: None     Source Type: Book    
DOI: 10.1201/9780203491232-7     Document Type: Chapter

References (55)

1. Hubbell, J.A., Synthetic biodegradable polymers for tissue engineering and drug delivery, Curr. Opin. Solid State & Mater. Sci., 3, 246, 1998.
2. Hatefi, A. and Amsden B., Biodegradable injectable in situ forming drug delivery systems, J. Control. Release, 80, 9, 2002.
3. Dordunoo, S.K. et al., Release of taxol from poly(ɛ-caprolactone) pastes: effect of water-soluble additives, J. Control. Release, 44, 87, 1997.
4. Zhang, X. et al., Development of biodegradable polymeric paste formulations for taxol: an in vitro and in vivo study, Int. J. Pharm., 137, 199, 1996.
5. Winternitz, C.I. et al., Development of a polymeric surgical paste formulation for taxol, Pharm. Res., 13, 368, 1996.
6. Davis, P.A. and Cousins, S., Biodegradable Injectable Drug Delivery Polymer, U.S. Patent 5,384,333, 1995.
7. Lautenschlager, E.P., Stupp, S.I., and Keller, J.C., Structure and properties of acrylic bone cement, in Functional Behaviour of Orthopaedic Biomaterials. Vol. II: Applications, Ducheyne, P. and Hastings, G.W., Eds., CRC, Boca Raton, 1984, chap. 4.
8. Hill-West, J. et al., Prevention of postoperative adhesions in the rat by in situ photopolymerization of bioresorbable hydrogel barriers, Obstet. Gynecol., 83, 59, 1994.
9. Metter, A.T., Anseth, K.S., and Bowman, C.N., Fundamental studies of a novel, biodegradable PEGb-PLA hydrogel, Polymer, 41, 3993, 2000.
10. Lu, S. and Anseth, K.S., Photopolymerization of multilaminated poly(HEMA) hydrogels for controlled release, J. Control. Release, 57, 291, 1999.
11. Méndez, J.A. et al., Self-curing acrylic formulations containing PMMA/PCL composites: properties and antibiotic release behavior, J. Biomed. Mater. Res., 61, 66, 2002.
12. Gerhart, T.N. et al., Antibiotic release from an experimental biodegradable bone cement, J. Orthopaed. Res., 6, 585, 1988.
13. Boesel, L.F. et al., Hydrogels and hydrophilic partially degradable bone cements based on biodegradable blends incorporating starch, in Biodegradable Polymers and Plastics, Chiellini, E., Ed., Kluwer Academic, Dordrecht, 2003, chap. 16.
14. Dunn, R.L. et al., Biodegradable In-Situ Forming Implants and Methods for Producing the Same, U.S. Patent 5,340,849, 1994.
15. Anseth, K.S., Shastri, V.R., and Langer, R., Photopolymerizable degradable polyanhydrides, Nat. Biotech., 17, 156, 1999.
16. Bryant, S.J. and Anseth, K.S., The effect of hydrogel thickness on tissue engineered cartilage in photocrosslinked poly(ethylene oxide) networks, Biomaterials, 22, 619, 2001.
17. Mason, M.N. et al., Predicting controlled-release behaviour of degradable PLA-b-PEG-b-PLA hydrogels, Macromolecules, 34, 4630, 2001.
18. Eliaz, R.E. and Kost, J., Characterization of a polymeric PLGA-injectable implant delivery system for the controlled release of proteins, J. Biomed. Mater. Res., 50, 388, 2000.
19. Shah, N.H. et al., A biodegradable injectable implant for delivering micro and macromolecules using poly(lactic-co-glycolic) acid (PLGA) copolymers, J. Control. Release, 27, 139, 1993.
20. Lambert, W.J. and Peck, K.D., Development of an in situ forming biodegradable poly(lactide-coglycolide) system for the controlled release of proteins, J. Control. Release, 33, 189, 1995.
21. Chandrashekar, B.L. et al., Controlled Release Liquid Delivery Compositions with Low Initial Drug Burst, U.S. Patent 6,143,314, 2000.
22. Jain, R.A., The manufacturing techniques of various drug loaded biodegradable poly(lactide-coglycolide) (PLGA) devices, Biomaterials, 21, 2475, 2000.
23. Eliaz, R.E. and Szoka, F.C., Jr., Robust and prolonged gene expression from injectable polymeric implants, Gene Therapy, 9, 1230, 2002.
24. Chenite, A. et al., Novel injectable neutral solutions of chitosan form biodegradable gels in situ, Biomaterials, 21, 2155, 2000.
25. Qiu, Y. and Park, K., Environment-sensitive hydrogels for drug delivery. Adv. Drug Del. Rev., 53, 321, 2001.
26. Johnston, T.P. and Palmer, W.K., Mechanism of poloxamer 407 induced hypertriglyceridemia in the rat, Biochem. Pharmacol., 46, 1037, 1993.
27. Jeong, B. et al., Biodegradable block copolymers as injectable drug delivery systems, Nature, 388, 860, 1997.
28. Chung, Y.M. et al., Sol-gel transition temperature of PLGA-g-PEG aqueous solutions, Biomacromolecules, 3, 511, 2002.
29. Gutowska, A., Jeong, B., and Jasionowski, M., Injectable gels for tissue engineering, The Anatomical Record, 263, 342, 2001.
30. Duranti, F. et al., Injectable hyaluronic acid gel for tissue augmentation. A clinical and histological study, Dermatol. Surg., 24, 1317, 1998.
31. Radomsky, M.L. et al., Novel formulation of fibroblast growth factor-2 in a hyaluronan gel accelerates fracture healing in nonhuman primates, J. Orthopaed. Res., 17, 607, 1999.
32. Anseth, K.S. et al., In situ forming degradable networks and their application in tissue engineering and drug delivery, J. Control. Release, 78, 199, 2002.
33. Siegal, R.A., Modeling of drug release from porous polymers, in Controlled Release of Drugs, Polymer and Aggregate System, Rosoff, M., Ed., VCH Publishers, New York, 1990, pp. 1–51.
34. Einmahl, S. et al., Therapeutic applications of viscous and injectable poly(ortho esters), Adv. Drug Del. Rev., 53, 45, 2001.
35. Merkli, A. et al., Purity and stability assessment of a semi-solid poly(ortho ester) used in drug delivery system, Biomaterials, 17, 897, 1996.
36. Schwach-Abdellaoui, K., Heller, J., and Gurny, R., Hydrolysis and erosion studies of autocatalyzed poly(ortho esters) containing lactoyl-lactyl acid dimers, Macromolecules, 32, 301, 1999.
37. Merkli, A. et al., Semi-solid hydrophobic bioerodible poly(ortho ester) for potential application in glaucoma filtering surgery, J. Control. Release, 29, 105, 1994.
38. Einmahl, S. et al., Concomitant and controlled release of dexamethasone and 5-fluorouracil from poly(ortho ester), Int. J. Pharm., 185, 189, 1999.
39. Zignani, M. et al., Improved biocompatibility of a viscous bioerodible poly(ortho ester) by controlling the environmental pH during degradation, Biomaterials, 21, 1773, 2000.
40. Kang, J.C. and Schwendeman, S.P., Comparison of the effects of Mg(OH)2 and sucrose on the stability of bovine serum albumin encapsulated in injectable poly(D,L-lactide-co-glycolide) implants, Biomaterials, 23, 239, 2002.
41. Jeong, B., Bae, Y.H., and Kim, S.W., Thermoreversible gelation of PEG-PLGA-PEG triblock copolymer aqueous solutions, Macromolecules, 32, 7064, 1999.
42. Jeong, B. et al., In situ gelation of PEG-PLGA-PEG triblock copolymer aqueous solutions and degradation thereof, J. Biomed. Mater. Res., 50, 171, 2000.
43. Jeong, B. et al., Biodegradable thermoreversible gelling PLGA-g-PEG copolymer, Chem. Commun., 16, 1516, 2001.
44. Jeong, B. et al., Thermogelling biodegradable polymers with hydrophilic backbones: PEG-g-PLGA, Macromolecules, 33, 8317, 2000.
45. Jeong, B. and Gutowska, A., Lessons from nature: stimuli-responsive polymers and their biomedical applications, Trends in Biotechnol., 20, 305, 2002.
46. Jeong, B. et al., Thermogelling biodegradable copolymer aqueous solutions for injectable protein delivery and tissue engineering, Biomacromolecules, 3, 865, 2002.
47. Chenite, A. et al., Rheological characterisation of thermogelling chitosan/glycerol-phosphate solutions, Carbohyd. Polym., 46, 39, 2001.
48. Ruel-Gariépy, E. et al., Characterization of thermosensitive chitosan gels for the sustained delivery of drugs, Int. J. Pharm., 203, 89, 2000.
49. Lee, K.Y., Alsberg, E., and Mooney, D.J., Degradable and injectable poly(aldehyde guluronate) hydrogels for bone tissue engineering, J. Biomed. Mater. Res., 56, 228, 2001.
50. West, J.L. and Hubbell, J.A., Polymeric biomaterials with degradation sites for proteases involved in cell migration, Macromolecules, 32, 241, 1999.
51. Mann, B.K. et al., Smooth muscle cell growth in photopolymerized hydrogels with cell adhesive and proteolytically degradable domains: synthetic ECM analogs for tissue engineering, Biomaterials, 22, 3045, 2001.
52. Sawhney, A.S., Pathak, C.P., and Hubbell, J.A., Bioerodible hydrogels based on photopolymerized poly(ethylene glycol)-co-poly(a-hydroxy acid) diacrylate macromers, Macromolecules, 26, 581, 1993.
53. Brem, H. et al., Placebo-controlled trial of safety and efficacy of intraoperative controlled delivery by biodegradable polymers of chemotherapy for recurrent gliomas, Lancet, 345, 1008, 1995.
54. Nguyen, K.T. and West, J.L., Photopolymerizable hydrogels for tissue engineering applications, Biomaterials, 23, 4307, 2002.
55. Wise, D.L. et al., Bioerodible Polymeric Semi-interpenetrating Network Alloys for Internal Fixation Devices and Bone Cements, U.S. Patent 6,486,232, 2002.