Development of a polymeric surgical paste formulation for taxol

Pharmaceutical Research

Volumn 13, Issue 3, 1996, Pages 368-375

  Winternitz, Charles I ^a   Jackson, John K ^a   Oktaba, Ann Marie ^b   Burt, Helen M ^a  

^a UNIVERSITY OF BRITISH COLUMBIA   (Canada)

^b Angiogenesis Technologies Inc   (Canada)

Author keywords

Biodegradable polymers; Methoxypolyethylene glycol; Poly( caprolactone); Sustained release; Taxol

Indexed keywords

ANGIOGENESIS INHIBITOR; METHOXYPOLYETHYLENEGLYCOL; PACLITAXEL; POLYCAPROLACTONE; POLYMER; UNCLASSIFIED DRUG;

ANGIOGENESIS; ANIMAL CELL; ANIMAL TISSUE; ARTICLE; CHICKEN; CHORIOALLANTOIS; DRUG ACTIVITY; DRUG FORMULATION; DRUG RELEASE; GEL PERMEATION CHROMATOGRAPHY; NONHUMAN; PRIORITY JOURNAL; SCANNING ELECTRON MICROSCOPY; SUSTAINED RELEASE PREPARATION; TENSILE STRENGTH; THERMAL ANALYSIS;

ALLANTOIS; ANIMALS; ANTINEOPLASTIC AGENTS, PHYTOGENIC; CHEMISTRY, PHARMACEUTICAL; CHICK EMBRYO; CHORION; NEOVASCULARIZATION, PHYSIOLOGIC; OINTMENTS; PACLITAXEL; POLYESTERS; POLYETHYLENE GLYCOLS;

EID: 0030003465     PISSN: 07248741     EISSN: None     Source Type: Journal    
DOI: 10.1023/A:1016032207246     Document Type: Article

References (26)

1. C. M. Spencer and D. Faulds. Paclitaxel: a review of its pharmacodynamic and pharmacokinetic properties and therapeutic potential in the treatment of cancer. Drugs. 48:794-847 (1994).
2. N. Onetto, R. Canetta, B. Winograd, R. Catane, M. Dougan, J. Grechko, J. Burroughs and M. Rozencweig. Overview of taxol safety. Journal of the National Cancer Institute Monographs. 15:131-139 (1993).
3. A. M. C. Oktaba, W. L. Hunter and A. L. Arsenault. Taxol: a potent inhibitor of angiogenesis and tumor angiogenesis. Submitted to International Journal of Cancer. (1995).
4. J. Folkman and M. Klagsburg. Angiogenic factors. Science. 235:442-447 (1987).
5. M. E. Stearns and M. Wang. Taxol blocks processes essential for prostate tumour cell (PC-3 ML) invasion and metastases. Cancer Research. 52:3776-3781 (1992).
6. V. T. Devita, Jr., S. Hellman and S. A. Rosenberg, (eds.) Cancer: Principles and Practice of Oncology. 3rd ed. Philadelphia: J. B. Lippincott Co., 1989.
7. F. H. Hochberg and A. Pruitt. Assumptions in the radiotherapy of glioblastoma. Neurology. 30:907-911 (1980).
8. K. E. Wallner, J. H. Galicich, G. Krol, E. Arbit and M. G. Malkin. Patterns of failure following treatment for glioblastoma multiforme and anaplastic astrocytoma. International Journal of Radiation Oncology Biology and Physics. 16:1405-1409 (1988).
9. C. G. Pitt. Poly-ε-caprolactone and its copolymers. In M. Chasinand R. Langer eds. Biodegradable Polymers as Drug Delivery Systems, Marcel Dekker: New York, 1990, pp. 71-120.
10. C. G. Pitt, M. M. Gratzl, A. R. Jeffcoat, R. Zweidinger and A. Schindler. Sustained drug delivery ststems II: factors affecting release rates from poly(ε-caprolactone) and related biodegradable polyesters. Journal of Pharmaceutical Sciences. 68:1534-1538 (1979).
11. G. Perego, G. D. Cella, N. N. Aldini, M. Fini and R. Giardino. Preparation of a new nerve guide from a poly(L-lactide-co-6-caprolactone). Biomaterials. 15:189-193 (1994).
12. P. Bruin, J. Smedinga, A. J. Pennings and M. F. Jonkman. Biodegradable lysine diisocyanate-based poly(glycolide-co-ε-caprolactone)-urethane network in artificial skin. Biomaterials. 11:291-295 (1990).
13. C. G. Pitt, M. M. Gratzl, G. L. Kimmel, J. Surles and A. Schindler. Aliphatic polyesters II. The degradation of poly(DL-lactide), poly(ε-caprolactone), and their copolymers in vivo. Biomaterials. 2:215-220 (1981).
14. S. C. Woodward, P. S. Brewer, F. Moatamed, A. Schindler and C. G. Pitt. The intracellular degradation of poly(ε-caprolactone). Journal of Biomedical Materials Research. 19:437-444 (1985).
15. O. F. Solomon and I. Z. Ciuta. Détermination di la viscosité intrinsèque de solutions de polymères par une simple détermination de la viscosité. Journal of Applied Polymer Science. 6:683-686 (1962).
16. J. D. Dugan, Jr., M. T. Lawton, B. Glaser and H. Brem. A new technique for explantation and in vitro cultivation of chicken embryos. The Anatomical Record. 229:125-128 (1991).
17. S. L. Rosen. Fundamental Principles of Polymeric Materials. (Second Edition) John Wiley & Sons, Inc., New York, 1993.
18. J. M. G. Cowie. Polymers: Chemistry & Physics of Modern Materials. International Textbook Company Limited, Aylesbury, 1973.
19. J. D. Adams, K. P. Flora, B. R. Goldspiel, J. W. Wilson, S. G. Arbuck and R. Finley. Taxol: a history of pharmaceutical development and current pharmaceutical concerns. Journal of the National Cancer Institute Monographs. 15:141-147 (1993).
20. R. Bawa, R. A. Siegel, B. Marasca, M. Karel and R. Langer. An explanation for the controlled release of macromolecules from polymers. Journal of Controlled Release. 1:259-267 (1985).
21. R. A. Siegel and R. Langer. Mechanistic studies of macromolecular drug release from macroporous polymers. II. Models for the slow kinetics of drug release. Journal of Controlled Release. 14:153-167 (1990).
22. C. Sturesson, J. Carlfors, K. Edsman and M. Andersson. Preparation of biodegradable poly(lactic-co-glycolic) acid microspheres and their in vitro release of timolol maleate. International Journal of Pharmaceutics. 89:235-244 (1993).
23. J. Folkman. Toward an understanding of angiogenesis: search and discovery. Perspectives in Biology and Medicine. 29:10-36 (1985).
24. R. Steiner. Angiostatic activity of anticancer agents in the chick embryo chorioallantoic membrane (CHE-CAM) assay. In R. Steiner, P. B. Weiszand R. Langer eds. Angiogenesis, Birkhauser Verlag: Berlin, 1992, pp. 449-454.
25. O. Kubo, Y. Tajika, Y. Muragaki, H. Hiyama, K. Takakura, M. Yoshida and M. Kumakura. Local chemotherapy with slowly-releasing anticancer drug-polymers for malignant brain tumors. Journal of Controlled Release. 32:1-8 (1994).
26. K. A. Walter, M. A. Cahan, A. Gur, B. Tyler, J. Hilton, O. M. Colvin, P. C. Burger, A. Domb and H. Brem. Interstitial taxol delivered from a biodegradable polymer implant against experimental malignant glioma. Cancer Research. 54:2207-2212 (1994).