-
1
-
-
19444375492
-
Mammalian flavin-containing monooxygenases: Structure/function, genetic polymorphisms and role in drug metabolism
-
KRUEGER SK, WILLIAMS DE: Mammalian flavin-containing monooxygenases: structure/function, genetic polymorphisms and role in drug metabolism. Pharmacol. Ther. (2005) 106(3):357-387.
-
(2005)
Pharmacol. Ther
, vol.106
, Issue.3
, pp. 357-387
-
-
KRUEGER, S.K.1
WILLIAMS, D.E.2
-
2
-
-
0028945438
-
Structural and catalytic properties of the mammalian flavin-containing monooxygenase
-
CASHMAN JR: Structural and catalytic properties of the mammalian flavin-containing monooxygenase. Chem. Res. Toxicol. (1995) 8(2):166-181.
-
(1995)
Chem. Res. Toxicol
, vol.8
, Issue.2
, pp. 166-181
-
-
CASHMAN, J.R.1
-
3
-
-
0036076899
-
Alternative processing of the human FMO6 gene renders transcripts incapable of encoding a functional flavin-containing monooxygenase
-
HINES RN, HOPP KA, FRANCO J, SAEIAN K, BEGUN FP: Alternative processing of the human FMO6 gene renders transcripts incapable of encoding a functional flavin-containing monooxygenase. Mol. Pharmacol. (2002) 62(2):320-325.
-
(2002)
Mol. Pharmacol
, vol.62
, Issue.2
, pp. 320-325
-
-
HINES, R.N.1
HOPP, K.A.2
FRANCO, J.3
SAEIAN, K.4
BEGUN, F.P.5
-
4
-
-
1342309263
-
Organization and evolution of the flavin-containing monooxygenase genes of human and mouse: Identification of novel gene and pseudogene clusters
-
HERNANDEZ D, JANMOHAMED A, CHANDAN P, PHILLIPS IR, SHEPHARD EA: Organization and evolution of the flavin-containing monooxygenase genes of human and mouse: identification of novel gene and pseudogene clusters. Pharmacogenetics (2004) 14(2):117-130.
-
(2004)
Pharmacogenetics
, vol.14
, Issue.2
, pp. 117-130
-
-
HERNANDEZ, D.1
JANMOHAMED, A.2
CHANDAN, P.3
PHILLIPS, I.R.4
SHEPHARD, E.A.5
-
5
-
-
12244306252
-
Identification of novel variants of the flavin-containing monooxygenase gene family in African Americans
-
FURNES B, FENG J, SOMMER SS, SCHLENK D: Identification of novel variants of the flavin-containing monooxygenase gene family in African Americans. Drug Metab. Dispos. (2003) 31(2):187-193.
-
(2003)
Drug Metab. Dispos
, vol.31
, Issue.2
, pp. 187-193
-
-
FURNES, B.1
FENG, J.2
SOMMER, S.S.3
SCHLENK, D.4
-
6
-
-
0037390952
-
Biochemical and clinical aspects of the human flavin-containing monooxygenase form 3 (FMO3) related to trimethylaminuria
-
CASHMAN JR, CAMP K, FAKHARZADEH SS et al.: Biochemical and clinical aspects of the human flavin-containing monooxygenase form 3 (FMO3) related to trimethylaminuria. Curr. Drug Metab. (2003) 4(2):151-170.
-
(2003)
Curr. Drug Metab
, vol.4
, Issue.2
, pp. 151-170
-
-
CASHMAN, J.R.1
CAMP, K.2
FAKHARZADEH, S.S.3
-
8
-
-
1542541519
-
Chemoprevention strategies using NSAIDs and COX-2 inhibitors
-
KELLER JJ, GIARDIELLO FM: Chemoprevention strategies using NSAIDs and COX-2 inhibitors. Cancer Biol. Ther. (2003) 2(4 Suppl. 1):S140-S149.
-
(2003)
Cancer Biol. Ther
, vol.2
, Issue.4 SUPPL. 1
-
-
KELLER, J.J.1
GIARDIELLO, F.M.2
-
9
-
-
11144226352
-
Genetic polymorphisms of human flavin monooxygenase 3 in sulindac-mediated primary chemoprevention of familial adenomatous polyposis
-
HISAMUDDIN IM, WEHBI MA, CHAO A et al.: Genetic polymorphisms of human flavin monooxygenase 3 in sulindac-mediated primary chemoprevention of familial adenomatous polyposis. Clin. Cancer Res. (2004) 10(24):8357-8362.
-
(2004)
Clin. Cancer Res
, vol.10
, Issue.24
, pp. 8357-8362
-
-
HISAMUDDIN, I.M.1
WEHBI, M.A.2
CHAO, A.3
-
10
-
-
0035201442
-
Population distribution of human flavin-containmg monooxygenase form 3: Gene polymorphisms
-
CASHMAN JR, ZHANG J, LEUSHNER J, BRAUN A: Population distribution of human flavin-containmg monooxygenase form 3: gene polymorphisms. Drug Metab. Dispos. (2001) 29(12):1629-1637.
-
(2001)
Drug Metab. Dispos
, vol.29
, Issue.12
, pp. 1629-1637
-
-
CASHMAN, J.R.1
ZHANG, J.2
LEUSHNER, J.3
BRAUN, A.4
-
11
-
-
26444452200
-
Genetic polymorphisms of flavin monooxygenase 3 in sulindac-induced regression of colorectal adenomas in familial adenomatous polyposis
-
HISAMUDDIN IM, WEHBI MA, SCHMOTZER B et al.: Genetic polymorphisms of flavin monooxygenase 3 in sulindac-induced regression of colorectal adenomas in familial adenomatous polyposis. Cancer Epidemiol. Biomark. Prev. (2005) 14(10):2366-2369.
-
(2005)
Cancer Epidemiol. Biomark. Prev
, vol.14
, Issue.10
, pp. 2366-2369
-
-
HISAMUDDIN, I.M.1
WEHBI, M.A.2
SCHMOTZER, B.3
-
12
-
-
33847342912
-
Effect of genetic variants of the human flavin-containing monooxygenase 3 on N- and S-oxygenation activities
-
SHIMIZU M, YANO H, NAGASHIMA S et al.: Effect of genetic variants of the human flavin-containing monooxygenase 3 on N- and S-oxygenation activities. Drug Metab. Dispos. (2007) 35 (3):328-330.
-
(2007)
Drug Metab. Dispos
, vol.35
, Issue.3
, pp. 328-330
-
-
SHIMIZU, M.1
YANO, H.2
NAGASHIMA, S.3
-
13
-
-
33646712592
-
The role of flavin-containing monooxygenase (FMO) in the metabolism of tamoxifen and other tertiary amines
-
KRUEGER SK, VANDYKE JE, WILLIAMS DE, HINES RN: The role of flavin-containing monooxygenase (FMO) in the metabolism of tamoxifen and other tertiary amines. Drug Metab. Rev. (2006) 38(1-2):139-147.
-
(2006)
Drug Metab. Rev
, vol.38
, Issue.1-2
, pp. 139-147
-
-
KRUEGER, S.K.1
VANDYKE, J.E.2
WILLIAMS, D.E.3
HINES, R.N.4
-
14
-
-
0043092271
-
Identification of tamoxifen-DNA adducts in monkeys treated with tamoxifen
-
SHIBUTANI S, SUZUKI N, LAXMI YR et al.: Identification of tamoxifen-DNA adducts in monkeys treated with tamoxifen. Cancer Res. (2003) 63(15):4402-4406.
-
(2003)
Cancer Res
, vol.63
, Issue.15
, pp. 4402-4406
-
-
SHIBUTANI, S.1
SUZUKI, N.2
LAXMI, Y.R.3
-
15
-
-
0034989609
-
Understanding the genotoxicity of tamoxifen?
-
PHILLIPS DH: Understanding the genotoxicity of tamoxifen? Carcinogenesis (2001) 22(6):839-849.
-
(2001)
Carcinogenesis
, vol.22
, Issue.6
, pp. 839-849
-
-
PHILLIPS, D.H.1
-
16
-
-
18944400868
-
Formation of tamoxifen-DNA adducts in human endometrial explants exposed to α-hydroxytamoxifen
-
KIM SY, SUZUKI N, LAXMI YR et al.: Formation of tamoxifen-DNA adducts in human endometrial explants exposed to α-hydroxytamoxifen. Chem. Res. Toxicol. (2005) 18(5):889-895.
-
(2005)
Chem. Res. Toxicol
, vol.18
, Issue.5
, pp. 889-895
-
-
KIM, S.Y.1
SUZUKI, N.2
LAXMI, Y.R.3
-
17
-
-
0033763393
-
Oxidation of ranitidine by isozymes of flavin-containing monooxygenase and cytochrome P450
-
CHUNG WG, PARK CS, ROH HK, LEE WK, CHA YN: Oxidation of ranitidine by isozymes of flavin-containing monooxygenase and cytochrome P450. Jpn J. Pharmacol. (2000) 84(2):213-220.
-
(2000)
Jpn J. Pharmacol
, vol.84
, Issue.2
, pp. 213-220
-
-
CHUNG, W.G.1
PARK, C.S.2
ROH, H.K.3
LEE, W.K.4
CHA, Y.N.5
-
18
-
-
0034053228
-
Phenotypes of flavin-containing monooxygenase activity determined by ranitidine N-oxidation are positively correlated with genotypes of linked FMO3 gene mutations in a Korean population
-
KANG JH, CHUNG WG, LEE KH et al.: Phenotypes of flavin-containing monooxygenase activity determined by ranitidine N-oxidation are positively correlated with genotypes of linked FMO3 gene mutations in a Korean population. Pharmacogenetics (2000) 10(1):67-78.
-
(2000)
Pharmacogenetics
, vol.10
, Issue.1
, pp. 67-78
-
-
KANG, J.H.1
CHUNG, W.G.2
LEE, K.H.3
-
19
-
-
9244265499
-
Benzydamine metabolism in vivo is impaired in patients with deficiency of flavin-containing monooxygenase 3
-
MAYATEPEK E, FLOCK B, ZSCHOCKE J: Benzydamine metabolism in vivo is impaired in patients with deficiency of flavin-containing monooxygenase 3. Pharmacogenetics (2004) 14(11):775-777.
-
(2004)
Pharmacogenetics
, vol.14
, Issue.11
, pp. 775-777
-
-
MAYATEPEK, E.1
FLOCK, B.2
ZSCHOCKE, J.3
-
20
-
-
0032981915
-
N-oxygenation of amphetamine and methamphetamine by the human flavin-containing monooxygenase (form 3): Role in bioactivation and detoxication
-
CASHMAN JR, XIONG YN, XU L, JANOWSKY A: N-oxygenation of amphetamine and methamphetamine by the human flavin-containing monooxygenase (form 3): role in bioactivation and detoxication. J. Pharmacol. Exp. Ther. (1999) 288(3):1251-1260.
-
(1999)
J. Pharmacol. Exp. Ther
, vol.288
, Issue.3
, pp. 1251-1260
-
-
CASHMAN, J.R.1
XIONG, Y.N.2
XU, L.3
JANOWSKY, A.4
-
21
-
-
0029793702
-
Cisapride. Drug interactions of clinical significance
-
BEDFORD TA, ROWBOTHAM DJ: Cisapride. Drug interactions of clinical significance. Drug Saf. (1996) 15(3):167-175.
-
(1996)
Drug Saf
, vol.15
, Issue.3
, pp. 167-175
-
-
BEDFORD, T.A.1
ROWBOTHAM, D.J.2
-
22
-
-
0033820669
-
The involvement of flavin-containing monooxygenase but not CYP3A4 in metabolism of itopride hydrochloride, a gastroprokinetic agent: Comparison with cisapride and mosapride citrate
-
MUSHIRODA T, DOUYA R, TAKAHARA E, NAGATA O: The involvement of flavin-containing monooxygenase but not CYP3A4 in metabolism of itopride hydrochloride, a gastroprokinetic agent: comparison with cisapride and mosapride citrate. Drug Metab. Dispos. (2000) 28(10):1231-1237.
-
(2000)
Drug Metab. Dispos
, vol.28
, Issue.10
, pp. 1231-1237
-
-
MUSHIRODA, T.1
DOUYA, R.2
TAKAHARA, E.3
NAGATA, O.4
-
23
-
-
0035061010
-
Trimethylaminuria: The fish malodor syndrome
-
MITCHELL SC, SMITH RL: Trimethylaminuria: the fish malodor syndrome. Drug Metab. Dispos. (2001) 29(4 Part 2):517-521.
-
(2001)
Drug Metab. Dispos
, vol.29
, Issue.4 PART 2
, pp. 517-521
-
-
MITCHELL, S.C.1
SMITH, R.L.2
-
25
-
-
0034905367
-
In vivo variability of TMA oxidation is partially mediated by polymorphisms of the FMO3 gene
-
LAMBERT DM, MAMER OA, AKERMAN BR et al.: In vivo variability of TMA oxidation is partially mediated by polymorphisms of the FMO3 gene. Mol. Genet. Metab. (2001) 73(3):224-229.
-
(2001)
Mol. Genet. Metab
, vol.73
, Issue.3
, pp. 224-229
-
-
LAMBERT, D.M.1
MAMER, O.A.2
AKERMAN, B.R.3
-
26
-
-
0032888716
-
Trimethylaminuria is caused by mutations of the FMO3 gene in a North American cohort
-
AKERMAN BR, LEMASS H, CHOW LM et al.: Trimethylaminuria is caused by mutations of the FMO3 gene in a North American cohort. Mol. Genet. Metab. (1999) 68(1):24-31.
-
(1999)
Mol. Genet. Metab
, vol.68
, Issue.1
, pp. 24-31
-
-
AKERMAN, B.R.1
LEMASS, H.2
CHOW, L.M.3
-
27
-
-
0030897424
-
Studies on the discontinuous N-oxidation of trimethylamine among Jordanian, Ecuadorian and New Guinean populations
-
MITCHELL SC, ZHANG AQ, BARRETT T, AYESH R, SMITH RL: Studies on the discontinuous N-oxidation of trimethylamine among Jordanian, Ecuadorian and New Guinean populations. Pharmacogenetics (1997) 7(1):45-50.
-
(1997)
Pharmacogenetics
, vol.7
, Issue.1
, pp. 45-50
-
-
MITCHELL, S.C.1
ZHANG, A.Q.2
BARRETT, T.3
AYESH, R.4
SMITH, R.L.5
-
28
-
-
0027272625
-
The fish odour syndrome: Biochemical, familial, and clinical aspects
-
AYESH R, MITCHELL SC, ZHANG A, SMITH RL: The fish odour syndrome: biochemical, familial, and clinical aspects. BMJ (1993) 307(6905):655-657.
-
(1993)
BMJ
, vol.307
, Issue.6905
, pp. 655-657
-
-
AYESH, R.1
MITCHELL, S.C.2
ZHANG, A.3
SMITH, R.L.4
-
29
-
-
33645664025
-
Diagnosis and management of trimethylaminuria (FMO3 deficiency) in children
-
CHALMERS RA, BAIN MD, MICHELAKAKIS H, ZSCHOCKE J, ILES RA: Diagnosis and management of trimethylaminuria (FMO3 deficiency) in children. J. Inherit. Metab. Dis. (2006) 29(1):162-172.
-
(2006)
J. Inherit. Metab. Dis
, vol.29
, Issue.1
, pp. 162-172
-
-
CHALMERS, R.A.1
BAIN, M.D.2
MICHELAKAKIS, H.3
ZSCHOCKE, J.4
ILES, R.A.5
-
30
-
-
0030812964
-
Trimethylaminuria associated with seizures and behavioural disturbance: A case report
-
MCCONNELL HW, MITCHELL SC, SMITH RL, BREWSTER M: Trimethylaminuria associated with seizures and behavioural disturbance: a case report. Seizure (1997) 6(4):317-321.
-
(1997)
Seizure
, vol.6
, Issue.4
, pp. 317-321
-
-
MCCONNELL, H.W.1
MITCHELL, S.C.2
SMITH, R.L.3
BREWSTER, M.4
-
31
-
-
0344837748
-
Fish odour syndrome with features of both primary and secondary trimerhylaminuria
-
FRASER-ANDREWS EA, MANNING NJ, ASHTON GH et al.: Fish odour syndrome with features of both primary and secondary trimerhylaminuria. Clin. Exp. Dermatol. (2003) 28(2):203-205.
-
(2003)
Clin. Exp. Dermatol
, vol.28
, Issue.2
, pp. 203-205
-
-
FRASER-ANDREWS, E.A.1
MANNING, N.J.2
ASHTON, G.H.3
-
32
-
-
0033582091
-
Trimethylaminuria: Susceptibility of heterozygotes
-
MITCHELL SC: Trimethylaminuria: susceptibility of heterozygotes. Lancet (1999) 354(9196):2164-2165.
-
(1999)
Lancet
, vol.354
, Issue.9196
, pp. 2164-2165
-
-
MITCHELL, S.C.1
-
33
-
-
0033523477
-
Mild trimethylaminuria caused by common variants in FMO3 gene
-
ZSCHOCKE J, KOHLMUELLER RD, QUAK E et al.: Mild trimethylaminuria caused by common variants in FMO3 gene. Lancet (1999) 354(9181):834-835.
-
(1999)
Lancet
, vol.354
, Issue.9181
, pp. 834-835
-
-
ZSCHOCKE, J.1
KOHLMUELLER, R.D.2
QUAK, E.3
-
34
-
-
0036786378
-
Interindividual differences of human flavin-containing monooxygenase 3: Genetic polymorphisms and functional variation
-
CASHMAN JR, ZHANG J: Interindividual differences of human flavin-containing monooxygenase 3: genetic polymorphisms and functional variation. Drug Metab. Dispos. (2002) 30(10):1043-1052.
-
(2002)
Drug Metab. Dispos
, vol.30
, Issue.10
, pp. 1043-1052
-
-
CASHMAN, J.R.1
ZHANG, J.2
-
35
-
-
0030472235
-
Exacerbation of symptoms of fish-odour syndrome during menstruation
-
ZHANG AQ, MITCHELL SC, SMITH RL: Exacerbation of symptoms of fish-odour syndrome during menstruation. Lancet (1996) 348(9043):1740-1741.
-
(1996)
Lancet
, vol.348
, Issue.9043
, pp. 1740-1741
-
-
ZHANG, A.Q.1
MITCHELL, S.C.2
SMITH, R.L.3
-
36
-
-
1642390782
-
Effects of the dietary supplements, activated charcoal and copper chlorophyllin, on urinary excretion of nimethylamine in Japanese trimethylaminuria patients
-
YAMAZAKI H, FUJIEDA M, TOGASHI M et al.: Effects of the dietary supplements, activated charcoal and copper chlorophyllin, on urinary excretion of nimethylamine in Japanese trimethylaminuria patients. Life Sci. (2004) 74(22):2739-2747.
-
(2004)
Life Sci
, vol.74
, Issue.22
, pp. 2739-2747
-
-
YAMAZAKI, H.1
FUJIEDA, M.2
TOGASHI, M.3
-
37
-
-
0032802490
-
In vitro and in vivo inhibition of human flavin-containing monooxygenase form 3 (FMO3) in the presence of dietary indoles
-
CASHMAN JR, XIONG Y, LIN J et al.: In vitro and in vivo inhibition of human flavin-containing monooxygenase form 3 (FMO3) in the presence of dietary indoles. Biochem. Pharmacol. (1999) 58(6):1047-1055.
-
(1999)
Biochem. Pharmacol
, vol.58
, Issue.6
, pp. 1047-1055
-
-
CASHMAN, J.R.1
XIONG, Y.2
LIN, J.3
-
38
-
-
33646812867
-
Mutation, polymorphism and perspectives for the future of human flavin-containing monooxygenase 3
-
ZHOU J, SHEPHARD EA: Mutation, polymorphism and perspectives for the future of human flavin-containing monooxygenase 3. Mutat. Res. (2006) 612(3):165-171.
-
(2006)
Mutat. Res
, vol.612
, Issue.3
, pp. 165-171
-
-
ZHOU, J.1
SHEPHARD, E.A.2
-
39
-
-
0030377670
-
The fish-odor syndrome
-
MITCHELL SC: The fish-odor syndrome. Perspect. Biol. Med. (1996) 39(4):514-526.
-
(1996)
Perspect. Biol. Med
, vol.39
, Issue.4
, pp. 514-526
-
-
MITCHELL, S.C.1
-
40
-
-
0033029263
-
Dietary precursors of trimethylamine in man: A pilot study
-
ZHANG AQ, MITCHELL SC, SMITH RL: Dietary precursors of trimethylamine in man: a pilot study. Food Chem. Toxicol. (1999) 37(5):515-520.
-
(1999)
Food Chem. Toxicol
, vol.37
, Issue.5
, pp. 515-520
-
-
ZHANG, A.Q.1
MITCHELL, S.C.2
SMITH, R.L.3
-
41
-
-
7144253814
-
Mutations of the flavin-containing monooxygenase gene (FMO3) cause trimethylaminuria, a defect in detoxication
-
TREACY EP, AKERMAN BR, CHOW LM et al.: Mutations of the flavin-containing monooxygenase gene (FMO3) cause trimethylaminuria, a defect in detoxication. Hum. Mol. Genet. (1998) 7(5):839-845.
-
(1998)
Hum. Mol. Genet
, vol.7
, Issue.5
, pp. 839-845
-
-
TREACY, E.P.1
AKERMAN, B.R.2
CHOW, L.M.3
-
42
-
-
0036265797
-
Human flavin-containing monooxygenase (form 3): Polymorphisms and variations in chemical metabolism
-
CASHMAN JR: Human flavin-containing monooxygenase (form 3): polymorphisms and variations in chemical metabolism. Pharmacogenomics (2002) 3(3):325-339.
-
(2002)
Pharmacogenomics
, vol.3
, Issue.3
, pp. 325-339
-
-
CASHMAN, J.R.1
-
43
-
-
0023811530
-
Purification and comparison of liver microsomal flavin-containing monooxygenase from normal and streptozotocin-diabetic rats
-
ROUER E, ROUET P, DELPECH M, LEROUX JP: Purification and comparison of liver microsomal flavin-containing monooxygenase from normal and streptozotocin-diabetic rats. Biochem. Pharmacol. (1988) 37(18):3455-3459.
-
(1988)
Biochem. Pharmacol
, vol.37
, Issue.18
, pp. 3455-3459
-
-
ROUER, E.1
ROUET, P.2
DELPECH, M.3
LEROUX, J.P.4
-
44
-
-
0033913769
-
Potentiation of thioacetamide liver injury in diabetic rats is due to induced CYP2E1
-
WANG T, SHANKAR K, RONIS MJ, MEHENDALE HM: Potentiation of thioacetamide liver injury in diabetic rats is due to induced CYP2E1. J. Pharmacol. Exp. Ther. (2000) 294(2):473-479.
-
(2000)
J. Pharmacol. Exp. Ther
, vol.294
, Issue.2
, pp. 473-479
-
-
WANG, T.1
SHANKAR, K.2
RONIS, M.J.3
MEHENDALE, H.M.4
-
45
-
-
33644973332
-
Insulin in flavin-containing monooxygenase regulation. Flavin-containing moncoxygenase and cytochrome P450 activities in experimental diabetes
-
BORBAS T, BENKO B, DALMADI B, SZABO I, TIHANYI K: Insulin in flavin-containing monooxygenase regulation. Flavin-containing moncoxygenase and cytochrome P450 activities in experimental diabetes. Eur. J. Pharm. Sci. (2006) 28(1-2):51-58.
-
(2006)
Eur. J. Pharm. Sci
, vol.28
, Issue.1-2
, pp. 51-58
-
-
BORBAS, T.1
BENKO, B.2
DALMADI, B.3
SZABO, I.4
TIHANYI, K.5
-
46
-
-
0031570778
-
Regulation of mouse liver flavin-containing monooxygenases 1 and 3 by sex steroids
-
FALLS JG, RYU DY, CAO Y, LEVI PE, HODGSON E: Regulation of mouse liver flavin-containing monooxygenases 1 and 3 by sex steroids. Arch. Biochem. Biophys. (1997) 342(2):212-223.
-
(1997)
Arch. Biochem. Biophys
, vol.342
, Issue.2
, pp. 212-223
-
-
FALLS, J.G.1
RYU, D.Y.2
CAO, Y.3
LEVI, P.E.4
HODGSON, E.5
-
47
-
-
2442654220
-
Genes for systemic vascular complications are differentially expressed in the livers of type 2 diabetic patients
-
TAKAMURA T, SAKURAI M, OTA T et al.: Genes for systemic vascular complications are differentially expressed in the livers of type 2 diabetic patients. Diabetologia (2004) 47(4):638-647.
-
(2004)
Diabetologia
, vol.47
, Issue.4
, pp. 638-647
-
-
TAKAMURA, T.1
SAKURAI, M.2
OTA, T.3
-
48
-
-
0033828360
-
Abnormalities of flavin monooxygenase as an etiology for sideroblastic anemia
-
BARBER M, CONRAD ME, UMBREIT JN, BARTON JC, MOORE EG: Abnormalities of flavin monooxygenase as an etiology for sideroblastic anemia. Am. J. Hematol. (2000) 65(2):149-153.
-
(2000)
Am. J. Hematol
, vol.65
, Issue.2
, pp. 149-153
-
-
BARBER, M.1
CONRAD, M.E.2
UMBREIT, J.N.3
BARTON, J.C.4
MOORE, E.G.5
-
49
-
-
0037509928
-
Regulatory defects in liver and intestine implicate abnormal hepcidin and Cybrd1 expression in mouse hemochromatosis
-
MUCKENTHALER M, ROY CN, CUSTODIO AO et al.: Regulatory defects in liver and intestine implicate abnormal hepcidin and Cybrd1 expression in mouse hemochromatosis. Nat. Genet. (2003) 34(1):102-107.
-
(2003)
Nat. Genet
, vol.34
, Issue.1
, pp. 102-107
-
-
MUCKENTHALER, M.1
ROY, C.N.2
CUSTODIO, A.O.3
-
51
-
-
29144492916
-
Polymorphisms of the flavin containing monooxygenase 3 (FMO3) gene do not predispose to essential hypertension in Caucasians
-
DOLAN C, SHIELDS DC, STANTON A et al.: Polymorphisms of the flavin containing monooxygenase 3 (FMO3) gene do not predispose to essential hypertension in Caucasians. BMC Med Genet. (2005) 6:41.
-
(2005)
BMC Med Genet
, vol.6
, pp. 41
-
-
DOLAN, C.1
SHIELDS, D.C.2
STANTON, A.3
-
52
-
-
0034946354
-
Effect of salinity on flavin-containing monooxygenase expression and activity in rainbow trout (Oncorhynchus mykiss)
-
LARSEN BK, SCHLENK D: Effect of salinity on flavin-containing monooxygenase expression and activity in rainbow trout (Oncorhynchus mykiss). J. Comp. Physiol. [B] (2001) 171(5):421-429.
-
(2001)
J. Comp. Physiol. [B]
, vol.171
, Issue.5
, pp. 421-429
-
-
LARSEN, B.K.1
SCHLENK, D.2
-
53
-
-
0030877007
-
Detoxication of tyramine by the flavin-containing monooxygenase: Stereoselective formation of the trans oxime
-
LIN J, CASHMAN JR: Detoxication of tyramine by the flavin-containing monooxygenase: stereoselective formation of the trans oxime. Chem. Res. Toxicol. (1997) 10(8):842-852.
-
(1997)
Chem. Res. Toxicol
, vol.10
, Issue.8
, pp. 842-852
-
-
LIN, J.1
CASHMAN, J.R.2
-
54
-
-
0033959521
-
Population-specific polymorphisms of the human FMO3 gene: Significance for detoxication
-
CASHMAN JR, AKERMAN BR, FORREST SM, TREACY EP: Population-specific polymorphisms of the human FMO3 gene: significance for detoxication. Drug Metab. Dispos. (2000) 28(2):169-173.
-
(2000)
Drug Metab. Dispos
, vol.28
, Issue.2
, pp. 169-173
-
-
CASHMAN, J.R.1
AKERMAN, B.R.2
FORREST, S.M.3
TREACY, E.P.4
-
55
-
-
23044469807
-
Discovery of novel flavin-containing monooxygenase 3 (FMO3) single nucleotide polymorphisms and functional analysis of upsteam haplotype variants
-
KOUKOURITAKI SB, POCH MT, CABACUNGAN ET, MCCARVER DG, HINES RN: Discovery of novel flavin-containing monooxygenase 3 (FMO3) single nucleotide polymorphisms and functional analysis of upsteam haplotype variants. Mol. Pharmacol. (2005) 68(2):383-392.
-
(2005)
Mol. Pharmacol
, vol.68
, Issue.2
, pp. 383-392
-
-
KOUKOURITAKI, S.B.1
POCH, M.T.2
CABACUNGAN, E.T.3
MCCARVER, D.G.4
HINES, R.N.5
-
56
-
-
0042383168
-
Deleterious mutations in the flavin-containing monooxygenase 3 (FMO3) gene causing trimethylaminuria
-
ZHANG J, TRAN Q, LATTARD V, CASHMAN JR: Deleterious mutations in the flavin-containing monooxygenase 3 (FMO3) gene causing trimethylaminuria. Pharmacogenetics (2003) 13(8):495-500.
-
(2003)
Pharmacogenetics
, vol.13
, Issue.8
, pp. 495-500
-
-
ZHANG, J.1
TRAN, Q.2
LATTARD, V.3
CASHMAN, J.R.4
-
57
-
-
33646428097
-
A spectrum of molecular variation in a cohort of Italian families with trimethylaminuria: Identification of three novel mutations of the FMO3 gene
-
TERESA E, LONARDO F, FIUMARA A et al.: A spectrum of molecular variation in a cohort of Italian families with trimethylaminuria: identification of three novel mutations of the FMO3 gene. Mol. Genet. Metab. (2006) 88(2):192-195.
-
(2006)
Mol. Genet. Metab
, vol.88
, Issue.2
, pp. 192-195
-
-
TERESA, E.1
LONARDO, F.2
FIUMARA, A.3
-
58
-
-
0037460496
-
Primary trimethylaminuria or fish odor syndrome. A novel mutation in the first documented case in Spain
-
MAZON RAMOS A, GIL-SETAS A, BERRADE ZUBIRI S et al.: Primary trimethylaminuria or fish odor syndrome. A novel mutation in the first documented case in Spain. Med. Clin. (Barc.) (2003) 120(6):219-221.
-
(2003)
Med. Clin. (Barc.)
, vol.120
, Issue.6
, pp. 219-221
-
-
MAZON RAMOS, A.1
GIL-SETAS, A.2
BERRADE ZUBIRI, S.3
-
59
-
-
0034523352
-
Compound heterozygosity for missense mutations in the flavin-containing monooxygenase 3 (FMO3) gene in patients with fish-odour syndrome
-
DOLPHIN CT, JANMOHAMED A, SMITH RL, SHEPHARD EA, PHILLIPS IR: Compound heterozygosity for missense mutations in the flavin-containing monooxygenase 3 (FMO3) gene in patients with fish-odour syndrome. Pharmacogenetics (2000) 10(9):799-807.
-
(2000)
Pharmacogenetics
, vol.10
, Issue.9
, pp. 799-807
-
-
DOLPHIN, C.T.1
JANMOHAMED, A.2
SMITH, R.L.3
SHEPHARD, E.A.4
PHILLIPS, I.R.5
-
60
-
-
0030667523
-
Missense mutation in flavin-containing mono-oxygenase 3 gene, FMO3, underlies fish-odour syndrome
-
DOLPHIN CT, JANMOHAMED A, SMITH RL, SHEPHARD EA, PHILLIPS IR: Missense mutation in flavin-containing mono-oxygenase 3 gene, FMO3, underlies fish-odour syndrome. Nat. Genet. (1997) 17(4):491-494.
-
(1997)
Nat. Genet
, vol.17
, Issue.4
, pp. 491-494
-
-
DOLPHIN, C.T.1
JANMOHAMED, A.2
SMITH, R.L.3
SHEPHARD, E.A.4
PHILLIPS, I.R.5
-
61
-
-
34547668504
-
Functional characterization of genetic variants of human FMO3 associated with trimethylaminuria
-
YEUNG CK, ADMAN ET, RETTIE AE: Functional characterization of genetic variants of human FMO3 associated with trimethylaminuria. Arch. Biochem. Biophys. (2007) 464(2):251-259.
-
(2007)
Arch. Biochem. Biophys
, vol.464
, Issue.2
, pp. 251-259
-
-
YEUNG, C.K.1
ADMAN, E.T.2
RETTIE, A.E.3
-
62
-
-
0033008190
-
Sequence variations in the flavin-containing mono-oxygenase 3 gene (FMO3) in fish odour syndrome
-
BASARAB T, ASHTON GH, MENAGE HP, MCGRATH JA: Sequence variations in the flavin-containing mono-oxygenase 3 gene (FMO3) in fish odour syndrome. Br. J. Dermatol. (1999) 140(1):164-167.
-
(1999)
Br. J. Dermatol
, vol.140
, Issue.1
, pp. 164-167
-
-
BASARAB, T.1
ASHTON, G.H.2
MENAGE, H.P.3
MCGRATH, J.A.4
-
63
-
-
33845940735
-
Identification and functional analysis of common human flavin-containing monooxygenase 3 genetic variants
-
KOUKOURITAKI SB, POCH MT, HENDERSON MC et al.: Identification and functional analysis of common human flavin-containing monooxygenase 3 genetic variants. J. Pharmacol. Exp. Ther. (2007) 320(1):266-273.
-
(2007)
J. Pharmacol. Exp. Ther
, vol.320
, Issue.1
, pp. 266-273
-
-
KOUKOURITAKI, S.B.1
POCH, M.T.2
HENDERSON, M.C.3
-
64
-
-
1642350733
-
A mutation in the flavin-containing monooxygenase 3 gene and its effects on catalytic activity for N-oxidation of trimethylamine in vitro
-
KUBOTA M, NAKAMOTO Y, NAKAYAMA K et al.: A mutation in the flavin-containing monooxygenase 3 gene and its effects on catalytic activity for N-oxidation of trimethylamine in vitro. Drug Metab. Pharmacokinet. (2002) 17(3):207-213.
-
(2002)
Drug Metab. Pharmacokinet
, vol.17
, Issue.3
, pp. 207-213
-
-
KUBOTA, M.1
NAKAMOTO, Y.2
NAKAYAMA, K.3
-
65
-
-
0033918738
-
A novel mutation in the flavin-containing monooxygenase 3 gene, FM03, that causes fish-odour syndrome: Activity of the mutant enzyme assessed by proton NMR spectroscopy
-
MURPHY HC, DOLPHIN CT, JANMOHAMED A et al.: A novel mutation in the flavin-containing monooxygenase 3 gene, FM03, that causes fish-odour syndrome: activity of the mutant enzyme assessed by proton NMR spectroscopy. Pharmacogenetics (2000) 10(5):439-451.
-
(2000)
Pharmacogenetics
, vol.10
, Issue.5
, pp. 439-451
-
-
MURPHY, H.C.1
DOLPHIN, C.T.2
JANMOHAMED, A.3
-
66
-
-
34548795920
-
Genetic polymorphism of the flavin-containing monooxygenase 3 (FMO3) associated with trimethylaminuria (Fish odor syndrome): Observations from Japanese patients
-
YAMAZAKI H, SHIMIZU M: Genetic polymorphism of the flavin-containing monooxygenase 3 (FMO3) associated with trimethylaminuria (Fish odor syndrome): observations from Japanese patients. Curr. Drug Metab. (2007) 8(5):487-491.
-
(2007)
Curr. Drug Metab
, vol.8
, Issue.5
, pp. 487-491
-
-
YAMAZAKI, H.1
SHIMIZU, M.2
-
67
-
-
34047266588
-
Missense and nonsense mutations of the flavin-containing monooxygenase 3 gene in a Japanese cohort
-
SHIMIZU M, TOMIOKA S, MURAYAMA N, YAMAZAKI H: Missense and nonsense mutations of the flavin-containing monooxygenase 3 gene in a Japanese cohort. Drug Metab. Pharmacokinet. (2007) 22(1):61-64.
-
(2007)
Drug Metab. Pharmacokinet
, vol.22
, Issue.1
, pp. 61-64
-
-
SHIMIZU, M.1
TOMIOKA, S.2
MURAYAMA, N.3
YAMAZAKI, H.4
-
68
-
-
85012859655
-
Two novel single nucleotide polymorphisms (SNPs) of the FMO3 gene in Japanese
-
FUJIEDA M, YAMAZAKI H, TOGASHI M, SAITO T, KAMATAKI T: Two novel single nucleotide polymorphisms (SNPs) of the FMO3 gene in Japanese. Drug Metab. Pharmacokinet. (2003) 18(5):333-335.
-
(2003)
Drug Metab. Pharmacokinet
, vol.18
, Issue.5
, pp. 333-335
-
-
FUJIEDA, M.1
YAMAZAKI, H.2
TOGASHI, M.3
SAITO, T.4
KAMATAKI, T.5
-
69
-
-
0037974644
-
Two new polymorphisms of the FMO3 gene in Caucasian and African-American populations: Comparative genetic and functional studies
-
LATTARD V, ZHANG J, TRAN Q et al.: Two new polymorphisms of the FMO3 gene in Caucasian and African-American populations: comparative genetic and functional studies. Drug Metab. Dispos. (2003) 31(7):854-860.
-
(2003)
Drug Metab. Dispos
, vol.31
, Issue.7
, pp. 854-860
-
-
LATTARD, V.1
ZHANG, J.2
TRAN, Q.3
-
70
-
-
2442642701
-
Alternative processing events in human FMO genes
-
LATTARD V, ZHANG J, CASHMAN JR: Alternative processing events in human FMO genes. Mol. Pharmacol. (2004) 65(6):1517-1525.
-
(2004)
Mol. Pharmacol
, vol.65
, Issue.6
, pp. 1517-1525
-
-
LATTARD, V.1
ZHANG, J.2
CASHMAN, J.R.3
-
71
-
-
2942530688
-
The implications of polymorphisms in mammalian flavin-containing monooxygenases in drug discovery and development
-
CASHMAN JR: The implications of polymorphisms in mammalian flavin-containing monooxygenases in drug discovery and development. Drug Discov. Today (2004) 9(13):574-581.
-
(2004)
Drug Discov. Today
, vol.9
, Issue.13
, pp. 574-581
-
-
CASHMAN, J.R.1
-
72
-
-
0030791881
-
Human flavin-containing monooxygenase form 3: CDNA expression of the enzymes containing amino acid substitutions observed in individuals with trimethylaminuria
-
CASHMAN JR, BI YA, LIN J et al.: Human flavin-containing monooxygenase form 3: cDNA expression of the enzymes containing amino acid substitutions observed in individuals with trimethylaminuria. Chem. Res. Toxicol. (1997) 10(8):837-841.
-
(1997)
Chem. Res. Toxicol
, vol.10
, Issue.8
, pp. 837-841
-
-
CASHMAN, J.R.1
BI, Y.A.2
LIN, J.3
-
73
-
-
0346249629
-
Flavin monooxygenase 3 (FMO3) polymorphism in a white population: Allele frequencies, mutation linkage, and functional effects on clozapine and caffeine metabolism
-
SACHSE C, RUSCHEN S, DETTLING M et al.: Flavin monooxygenase 3 (FMO3) polymorphism in a white population: allele frequencies, mutation linkage, and functional effects on clozapine and caffeine metabolism. Clin. Pharmacol. Ther. (1999) 66(4):431-438.
-
(1999)
Clin. Pharmacol. Ther
, vol.66
, Issue.4
, pp. 431-438
-
-
SACHSE, C.1
RUSCHEN, S.2
DETTLING, M.3
-
74
-
-
27544496636
-
Some distinctions between flavin-containing and cytochrome P450 monooxygenases
-
CASHMAN JR: Some distinctions between flavin-containing and cytochrome P450 monooxygenases. Biochem. Biophys. Res. Commun. (2005) 338(1):599-604.
-
(2005)
Biochem. Biophys. Res. Commun
, vol.338
, Issue.1
, pp. 599-604
-
-
CASHMAN, J.R.1
-
75
-
-
37249047868
-
Identification of a novel R223Q missense mutation in the flavin-containing monooxygenase 3 gene in trimethylaminuria
-
PRETI G, UBRIANI R, KIM J et al.: Identification of a novel R223Q missense mutation in the flavin-containing monooxygenase 3 gene in trimethylaminuria. J. Invest. Dermatol. (2002) 119(1):207-350.
-
(2002)
J. Invest. Dermatol
, vol.119
, Issue.1
, pp. 207-350
-
-
PRETI, G.1
UBRIANI, R.2
KIM, J.3
-
76
-
-
0034280122
-
Human flavin-containing monooxygenase: Substrate specificity and role in drug metabolism
-
CASHMAN JR: Human flavin-containing monooxygenase: substrate specificity and role in drug metabolism. Curr. Drug Metab. (2000) 1(2):181-191.
-
(2000)
Curr. Drug Metab
, vol.1
, Issue.2
, pp. 181-191
-
-
CASHMAN, J.R.1
-
77
-
-
0030989682
-
-
TUGNAIT M, HAWES EM, MCKAY G et al.: N-oxygenation of clozapine by flavin-containing monooxygenase. Drug Metab. Dispos. (1997) 25(4):524-527.
-
TUGNAIT M, HAWES EM, MCKAY G et al.: N-oxygenation of clozapine by flavin-containing monooxygenase. Drug Metab. Dispos. (1997) 25(4):524-527.
-
-
-
-
78
-
-
33749010103
-
Enzyme-mediated protein haptenation of dapsone and sulfamethoxazole in human keratinocytes. II. Expression and role of flavin-containing monooxygenases and peroxidases
-
VYAS PM, ROYCHOWDHURY S, KOUKOURITAKI SB et al.: Enzyme-mediated protein haptenation of dapsone and sulfamethoxazole in human keratinocytes. II. Expression and role of flavin-containing monooxygenases and peroxidases. J. Pharmacol. Exp. Ther. (2006) 319(1):497-505.
-
(2006)
J. Pharmacol. Exp. Ther
, vol.319
, Issue.1
, pp. 497-505
-
-
VYAS, P.M.1
ROYCHOWDHURY, S.2
KOUKOURITAKI, S.B.3
-
79
-
-
0036893417
-
Effects of olopatadine, a new antiallergic agent, on human liver microsomal cytochrome P450 activities
-
KAJITA J, INANO K, FUSE E, KUWABARA T, KOBAYASHI H: Effects of olopatadine, a new antiallergic agent, on human liver microsomal cytochrome P450 activities. Drug Metab. Dispos. (2002) 30(12):1504-1511.
-
(2002)
Drug Metab. Dispos
, vol.30
, Issue.12
, pp. 1504-1511
-
-
KAJITA, J.1
INANO, K.2
FUSE, E.3
KUWABARA, T.4
KOBAYASHI, H.5
-
80
-
-
34247156182
-
Absorption and metabolism of albendazole after intestinal ischemia/reperfusion
-
MOLINA AJ, MERINO G, PRIETO JG et al.: Absorption and metabolism of albendazole after intestinal ischemia/reperfusion. Eur. J. Pharm. Sci. (2007) 31(1):16-24.
-
(2007)
Eur. J. Pharm. Sci
, vol.31
, Issue.1
, pp. 16-24
-
-
MOLINA, A.J.1
MERINO, G.2
PRIETO, J.G.3
-
81
-
-
0027261530
-
Chemical, enzymatic, and human enantioselective S-oxygenation of cimetidine
-
CASHMAN JR, PARK SB, YANG ZC et al.: Chemical, enzymatic, and human enantioselective S-oxygenation of cimetidine. Drug Metab. Dispos. (1993) 21(4):587-597.
-
(1993)
Drug Metab. Dispos
, vol.21
, Issue.4
, pp. 587-597
-
-
CASHMAN, J.R.1
PARK, S.B.2
YANG, Z.C.3
-
82
-
-
33645471799
-
Oxidative activarion of thiacetazone by the Mycobarterium tuberculosis flavin monooxygenase EtaA and human FMO1 and FMO3
-
QIAN L, ORTIZ DE MONTELLANO PR: Oxidative activarion of thiacetazone by the Mycobarterium tuberculosis flavin monooxygenase EtaA and human FMO1 and FMO3. Chem. Res. Toxicol. (2006) 19(3):443-449.
-
(2006)
Chem. Res. Toxicol
, vol.19
, Issue.3
, pp. 443-449
-
-
QIAN, L.1
ORTIZ DE MONTELLANO, P.R.2
-
83
-
-
0037378805
-
Cytochrome P450 2C8 and flavin-containing monooxygenases are involved in the metabolism of tazarotenic acid in humans
-
ATTAR M, DONG D, LING KH, TANG-LIU DD: Cytochrome P450 2C8 and flavin-containing monooxygenases are involved in the metabolism of tazarotenic acid in humans. Drug Metab. Dispos. (2003) 31(4):476-481.
-
(2003)
Drug Metab. Dispos
, vol.31
, Issue.4
, pp. 476-481
-
-
ATTAR, M.1
DONG, D.2
LING, K.H.3
TANG-LIU, D.D.4
|