-
1
-
-
19444375492
-
Mammalian flavin-containing monooxygenases: structure/function, genetic polymorphisms and role in drug metabolism
-
Krueger S.K., and Williams D.E. Mammalian flavin-containing monooxygenases: structure/function, genetic polymorphisms and role in drug metabolism. Pharmacol Ther 106 (2005) 357-387
-
(2005)
Pharmacol Ther
, vol.106
, pp. 357-387
-
-
Krueger, S.K.1
Williams, D.E.2
-
2
-
-
0026495269
-
Use of thiocarbamides as selective substrate probes for isoforms of flavin-containing monooxygenases
-
Guo W.X., Poulsen L.L., and Ziegler D.M. Use of thiocarbamides as selective substrate probes for isoforms of flavin-containing monooxygenases. Biochem Pharmacol 44 (1992) 2029-2037
-
(1992)
Biochem Pharmacol
, vol.44
, pp. 2029-2037
-
-
Guo, W.X.1
Poulsen, L.L.2
Ziegler, D.M.3
-
3
-
-
0034241811
-
Size limits of thiocarbamides accepted as substrates by human flavin-containing monooxygenase 1
-
Kim Y.M., and Ziegler D.M. Size limits of thiocarbamides accepted as substrates by human flavin-containing monooxygenase 1. Drug Metab Dispos 28 (2000) 1003-1006
-
(2000)
Drug Metab Dispos
, vol.28
, pp. 1003-1006
-
-
Kim, Y.M.1
Ziegler, D.M.2
-
4
-
-
0036609143
-
Thiourea toxicity in mouse C3H/10T12 cells expressing human flavin-dependent monooxygenase 3
-
Smith P.B., and Crespi C. Thiourea toxicity in mouse C3H/10T12 cells expressing human flavin-dependent monooxygenase 3. Biochem Pharmacol 63 (2002) 1941-1948
-
(2002)
Biochem Pharmacol
, vol.63
, pp. 1941-1948
-
-
Smith, P.B.1
Crespi, C.2
-
5
-
-
2442686708
-
Human flavin-containing monooxygenase form 2 S-oxygenation: sulfenic acid formation from thioureas and oxidation of glutathione
-
Henderson M.C., Krueger S.K., Stevens J.F., and Williams D.E. Human flavin-containing monooxygenase form 2 S-oxygenation: sulfenic acid formation from thioureas and oxidation of glutathione. Chem Res Toxicol 17 (2004) 633-640
-
(2004)
Chem Res Toxicol
, vol.17
, pp. 633-640
-
-
Henderson, M.C.1
Krueger, S.K.2
Stevens, J.F.3
Williams, D.E.4
-
6
-
-
0028302414
-
A nomenclature for the mammalian flavin-containing monooxygenase gene family based on amino acid sequence identities
-
Lawton M.P., Cashman J.R., Cresteil T., Dolphin C.T., Elfarra A.A., Hines R.N., et al. A nomenclature for the mammalian flavin-containing monooxygenase gene family based on amino acid sequence identities. Arch Biochem Biophys 308 (1994) 254-257
-
(1994)
Arch Biochem Biophys
, vol.308
, pp. 254-257
-
-
Lawton, M.P.1
Cashman, J.R.2
Cresteil, T.3
Dolphin, C.T.4
Elfarra, A.A.5
Hines, R.N.6
-
7
-
-
1342309263
-
Organization and evolution of the flavin-containing monooxygenase genes of human and mouse: identification of novel gene and pseudogene clusters
-
Hernandez D., Janmohamed A., Chandan P., Phillips I.R., and Shephard E.A. Organization and evolution of the flavin-containing monooxygenase genes of human and mouse: identification of novel gene and pseudogene clusters. Pharmacogenetics 14 (2004) 117-130
-
(2004)
Pharmacogenetics
, vol.14
, pp. 117-130
-
-
Hernandez, D.1
Janmohamed, A.2
Chandan, P.3
Phillips, I.R.4
Shephard, E.A.5
-
8
-
-
0036076899
-
Alternative processing of the human FMO6 gene renders transcripts incapable of encoding a functional flavin-containing monooxygenase
-
Hines R.N., Hopp K.A., Franco J., Saeian K., and Begun F.P. Alternative processing of the human FMO6 gene renders transcripts incapable of encoding a functional flavin-containing monooxygenase. Mol Pharmacol 62 (2002) 320-325
-
(2002)
Mol Pharmacol
, vol.62
, pp. 320-325
-
-
Hines, R.N.1
Hopp, K.A.2
Franco, J.3
Saeian, K.4
Begun, F.P.5
-
9
-
-
0021747810
-
Rabbit lung flavin-containing monooxygenase is immunochemically and catalytically distinct from the liver enzyme
-
Williams D.E., Ziegler D.M., Nordin D.J., Hale S.E., and Masters B.S. Rabbit lung flavin-containing monooxygenase is immunochemically and catalytically distinct from the liver enzyme. Biochem Biophys Res Commun 125 (1984) 116-122
-
(1984)
Biochem Biophys Res Commun
, vol.125
, pp. 116-122
-
-
Williams, D.E.1
Ziegler, D.M.2
Nordin, D.J.3
Hale, S.E.4
Masters, B.S.5
-
10
-
-
0021957282
-
Identification of distinct hepatic and pulmonary forms of microsomal flavin-containing monooxygenase in the mouse and rabbit
-
Tynes R.E., Sabourin P.J., and Hodgson E. Identification of distinct hepatic and pulmonary forms of microsomal flavin-containing monooxygenase in the mouse and rabbit. Biochem Biophys Res Commun 126 (1985) 1069-1075
-
(1985)
Biochem Biophys Res Commun
, vol.126
, pp. 1069-1075
-
-
Tynes, R.E.1
Sabourin, P.J.2
Hodgson, E.3
-
11
-
-
0025219896
-
The flavin-containing monooxygenase enzymes expressed in rabbit liver and lung are products of related but distinctly different genes
-
Lawton M.P., Gasser R., Tynes R.E., Hodgson E., and Philpot R.M. The flavin-containing monooxygenase enzymes expressed in rabbit liver and lung are products of related but distinctly different genes. J Biol Chem 265 (1990) 5855-5861
-
(1990)
J Biol Chem
, vol.265
, pp. 5855-5861
-
-
Lawton, M.P.1
Gasser, R.2
Tynes, R.E.3
Hodgson, E.4
Philpot, R.M.5
-
12
-
-
0026937248
-
Guinea pig or rabbit lung flavin-containing monooxygenases with distinct mobilities in SDS-PAGE are allelic variants that differ at only two positions
-
Nikbakht K.N., Lawton M.P., and Philpot R.M. Guinea pig or rabbit lung flavin-containing monooxygenases with distinct mobilities in SDS-PAGE are allelic variants that differ at only two positions. Pharmacogenetics 2 (1992) 207-216
-
(1992)
Pharmacogenetics
, vol.2
, pp. 207-216
-
-
Nikbakht, K.N.1
Lawton, M.P.2
Philpot, R.M.3
-
13
-
-
0031588975
-
Pulmonary flavin-containing monooxygenase (FMO) in rhesus macaque: expression of FMO2 protein, mRNA and analysis of the cDNA
-
Yueh M.-F., Krueger S.K., and Williams D.E. Pulmonary flavin-containing monooxygenase (FMO) in rhesus macaque: expression of FMO2 protein, mRNA and analysis of the cDNA. Biochim Biophys Acta 1350 (1997) 267-271
-
(1997)
Biochim Biophys Acta
, vol.1350
, pp. 267-271
-
-
Yueh, M.-F.1
Krueger, S.K.2
Williams, D.E.3
-
14
-
-
29944437885
-
Quantitative analysis of FMO gene mRNA levels in human tissues
-
Zhang J., and Cashman J.R. Quantitative analysis of FMO gene mRNA levels in human tissues. Drug Metab Dispos 34 (2006) 19-26
-
(2006)
Drug Metab Dispos
, vol.34
, pp. 19-26
-
-
Zhang, J.1
Cashman, J.R.2
-
15
-
-
0032515069
-
The flavin-containing monooxygenase 2 gene (FMO2) of humans, but not of other primates, encodes a truncated, nonfunctional protein
-
Dolphin C.T., Beckett D.J., Janmohamed A., Cullingford T.E., Smith R.L., Shephard E.A., et al. The flavin-containing monooxygenase 2 gene (FMO2) of humans, but not of other primates, encodes a truncated, nonfunctional protein. J Biol Chem 273 (1998) 30599-30607
-
(1998)
J Biol Chem
, vol.273
, pp. 30599-30607
-
-
Dolphin, C.T.1
Beckett, D.J.2
Janmohamed, A.3
Cullingford, T.E.4
Smith, R.L.5
Shephard, E.A.6
-
16
-
-
0036136926
-
Identification of active flavin-containing monooxygenase isoform 2 in human lung and characterization of expressed protein
-
Krueger S.K., Martin S.R., Yueh M.F., Pereira C.B., and Williams D.E. Identification of active flavin-containing monooxygenase isoform 2 in human lung and characterization of expressed protein. Drug Metab Dispos 30 (2002) 34-41
-
(2002)
Drug Metab Dispos
, vol.30
, pp. 34-41
-
-
Krueger, S.K.1
Martin, S.R.2
Yueh, M.F.3
Pereira, C.B.4
Williams, D.E.5
-
17
-
-
0034329485
-
Ethnic differences in human flavin-containing monooxygenase 2 (FMO2) polymorphisms: detection of expressed protein in African-Americans
-
Whetstine J.R., Yueh M.-F., McCarver D.G., Williams D.E., Park C.-S., Kang J.H., et al. Ethnic differences in human flavin-containing monooxygenase 2 (FMO2) polymorphisms: detection of expressed protein in African-Americans. Toxicol Appl Pharmacol 168 (2000) 216-224
-
(2000)
Toxicol Appl Pharmacol
, vol.168
, pp. 216-224
-
-
Whetstine, J.R.1
Yueh, M.-F.2
McCarver, D.G.3
Williams, D.E.4
Park, C.-S.5
Kang, J.H.6
-
18
-
-
12244306252
-
Identification of novel variants of the flavin-containing monooxygenase gene family in African Americans
-
Furnes B., Feng J., Sommer S.S., and Schlenk D. Identification of novel variants of the flavin-containing monooxygenase gene family in African Americans. Drug Metab Dispos 31 (2003) 187-193
-
(2003)
Drug Metab Dispos
, vol.31
, pp. 187-193
-
-
Furnes, B.1
Feng, J.2
Sommer, S.S.3
Schlenk, D.4
-
19
-
-
0036037640
-
Genetic polymorphisms of flavin-containing monooxygenase (FMO)
-
Krueger S.K., Williams D.E., Yueh M.F., Martin S.R., Hines R.N., Raucy J.L., et al. Genetic polymorphisms of flavin-containing monooxygenase (FMO). Drug Metab Rev 34 (2002) 523-532
-
(2002)
Drug Metab Rev
, vol.34
, pp. 523-532
-
-
Krueger, S.K.1
Williams, D.E.2
Yueh, M.F.3
Martin, S.R.4
Hines, R.N.5
Raucy, J.L.6
-
20
-
-
9444240466
-
Differences in Fmo2*1 allelic frequency between hispanics of Puerto Rican and Mexican descent
-
Krueger S.K., Siddens L.K., Martin S.R., Yu Z., Pereira C.B., Cabacungan E.T., et al. Differences in Fmo2*1 allelic frequency between hispanics of Puerto Rican and Mexican descent. Drug Metab Dispos 32 (2004) 1337-1340
-
(2004)
Drug Metab Dispos
, vol.32
, pp. 1337-1340
-
-
Krueger, S.K.1
Siddens, L.K.2
Martin, S.R.3
Yu, Z.4
Pereira, C.B.5
Cabacungan, E.T.6
-
21
-
-
20244385460
-
Haplotype and functional analysis of four flavin-containing monooxygenase isoform 2 (FMO2) polymorphisms in Hispanics
-
Krueger S.K., Siddens L.K., Henderson M.C., Andreasen E.A., Tanguay R.L., Pereira C.B., et al. Haplotype and functional analysis of four flavin-containing monooxygenase isoform 2 (FMO2) polymorphisms in Hispanics. Pharmacogenet Genomics 15 (2005) 245-256
-
(2005)
Pharmacogenet Genomics
, vol.15
, pp. 245-256
-
-
Krueger, S.K.1
Siddens, L.K.2
Henderson, M.C.3
Andreasen, E.A.4
Tanguay, R.L.5
Pereira, C.B.6
-
22
-
-
3843070896
-
S-oxygenation of the thioether organophosphate insecticides phorate and disulfoton by human lung flavin-containing monooxygenase 2
-
Henderson M.C., Krueger S.K., Siddens L.K., Stevens J.F., and Williams D.E. S-oxygenation of the thioether organophosphate insecticides phorate and disulfoton by human lung flavin-containing monooxygenase 2. Biochem Pharmacol 68 (2004) 959-967
-
(2004)
Biochem Pharmacol
, vol.68
, pp. 959-967
-
-
Henderson, M.C.1
Krueger, S.K.2
Siddens, L.K.3
Stevens, J.F.4
Williams, D.E.5
-
23
-
-
0036296503
-
The FMO2 gene of laboratory rats, as in most humans, encodes a truncated protein
-
Lattard V., Longin-Sauvageon C., Krueger S.K., Williams D.E., and Benoit E. The FMO2 gene of laboratory rats, as in most humans, encodes a truncated protein. Biochem Biophys Res Commun 292 (2002) 558-563
-
(2002)
Biochem Biophys Res Commun
, vol.292
, pp. 558-563
-
-
Lattard, V.1
Longin-Sauvageon, C.2
Krueger, S.K.3
Williams, D.E.4
Benoit, E.5
-
24
-
-
6944230852
-
Identification and characterization of the FMO2 gene in Rattus norvegicus: a good model to study metabolic and toxicological consequences of the FMO2 polymorphism
-
Hugonnard M., Benoit E., Longin-Sauvageon C., and Lattard V. Identification and characterization of the FMO2 gene in Rattus norvegicus: a good model to study metabolic and toxicological consequences of the FMO2 polymorphism. Pharmacogenetics 14 (2004) 647-655
-
(2004)
Pharmacogenetics
, vol.14
, pp. 647-655
-
-
Hugonnard, M.1
Benoit, E.2
Longin-Sauvageon, C.3
Lattard, V.4
-
25
-
-
0026919310
-
The flavin-containing monooxygenase in mouse lung: evidence for expression of multiple forms
-
Venkatesh K., Blake B., Levi P.E., and Hodgson E. The flavin-containing monooxygenase in mouse lung: evidence for expression of multiple forms. J Biochem Toxicol 7 (1992) 163-169
-
(1992)
J Biochem Toxicol
, vol.7
, pp. 163-169
-
-
Venkatesh, K.1
Blake, B.2
Levi, P.E.3
Hodgson, E.4
-
26
-
-
2942596156
-
Cell-, tissue-, sex- and developmental stage-specific expression of mouse flavin-containing monooxygenases (Fmos)
-
Janmohamed A., Hernandez D., Phillips I.R., and Shephard E.A. Cell-, tissue-, sex- and developmental stage-specific expression of mouse flavin-containing monooxygenases (Fmos). Biochem Pharmacol 68 (2004) 73-83
-
(2004)
Biochem Pharmacol
, vol.68
, pp. 73-83
-
-
Janmohamed, A.1
Hernandez, D.2
Phillips, I.R.3
Shephard, E.A.4
-
27
-
-
0000428146
-
Analysis and characterization of enzymes
-
Hayes A.W. (Ed), Raven Press, New York
-
Guengerich F.P. Analysis and characterization of enzymes. In: Hayes A.W. (Ed). Principles and Methods of Toxicology (1989), Raven Press, New York 777-814.
-
(1989)
Principles and Methods of Toxicology
-
-
Guengerich, F.P.1
-
28
-
-
0017184389
-
A rapid and sensitive method for the quantitation of microgram quantities of protein utilizing the principle of protein-dye binding
-
Bradford M.M. A rapid and sensitive method for the quantitation of microgram quantities of protein utilizing the principle of protein-dye binding. Anal Biochem 72 (1976) 248-254
-
(1976)
Anal Biochem
, vol.72
, pp. 248-254
-
-
Bradford, M.M.1
-
29
-
-
0021141593
-
Spectrophotometric assay of the flavin-containing monooxygenase and changes in its activity in female mouse liver with nutritional and diurnal conditions
-
Dixit A., and Roche T.E. Spectrophotometric assay of the flavin-containing monooxygenase and changes in its activity in female mouse liver with nutritional and diurnal conditions. Arch Biochem Biophys 233 (1984) 50-63
-
(1984)
Arch Biochem Biophys
, vol.233
, pp. 50-63
-
-
Dixit, A.1
Roche, T.E.2
-
30
-
-
0025295344
-
Stereoselective sulfoxidation of a series of alkyl p-tolyl sulfides by microsomal and purified flavin-containing monooxygenases
-
Rettie A.E., Bogucki B.D., Lim I., and Meier G.P. Stereoselective sulfoxidation of a series of alkyl p-tolyl sulfides by microsomal and purified flavin-containing monooxygenases. Mol Pharmacol 37 (1990) 643-651
-
(1990)
Mol Pharmacol
, vol.37
, pp. 643-651
-
-
Rettie, A.E.1
Bogucki, B.D.2
Lim, I.3
Meier, G.P.4
-
31
-
-
0037129827
-
-
Vandesompele J, De Preter K, Pattyn F, Poppe B, Van Roy N, De Paepe A, et al. Accurate normalization of real-time quantitative RT-PCR data by geometric averaging of multiple internal control genes. Genome Biol 2002; 3:RESEARCH0034.1-12.
-
-
-
-
32
-
-
0028343305
-
Prochiral sulfoxidation as a probe for multiple forms of the microsomal flavin-containing monooxygenase: studies with rabbit FMO1, FMO2, FMO3, and FMO5 expressed in Escherichia coli
-
Rettie A.E., Lawton M.P., Sadeque A.J., Meier G.P., and Philpot R.M. Prochiral sulfoxidation as a probe for multiple forms of the microsomal flavin-containing monooxygenase: studies with rabbit FMO1, FMO2, FMO3, and FMO5 expressed in Escherichia coli. Arch Biochem Biophys 311 (1994) 369-377
-
(1994)
Arch Biochem Biophys
, vol.311
, pp. 369-377
-
-
Rettie, A.E.1
Lawton, M.P.2
Sadeque, A.J.3
Meier, G.P.4
Philpot, R.M.5
-
33
-
-
0035039094
-
Characterization of expressed full-length and truncated FMO2 from rhesus monkey
-
Krueger S.K., Yueh M.-F., Martin S.R., Pereira C.B., and Williams D.E. Characterization of expressed full-length and truncated FMO2 from rhesus monkey. Drug Metab Dispos 29 (2001) 693-700
-
(2001)
Drug Metab Dispos
, vol.29
, pp. 693-700
-
-
Krueger, S.K.1
Yueh, M.-F.2
Martin, S.R.3
Pereira, C.B.4
Williams, D.E.5
-
34
-
-
33646168728
-
Per cell" normalization method for mRNA measurement by quantitative PCR and microarrays
-
Kanno J., Aisaki K., Igarashi K., Nakatsu N., Ono A., Kodama Y., et al. Per cell" normalization method for mRNA measurement by quantitative PCR and microarrays. BMC Genomics 7 (2006) 64
-
(2006)
BMC Genomics
, vol.7
, pp. 64
-
-
Kanno, J.1
Aisaki, K.2
Igarashi, K.3
Nakatsu, N.4
Ono, A.5
Kodama, Y.6
|